Diabetes Portal - Related Links
Databases and Websites:
RGD Phenotypes and Models: Diabetes
RGD Type 2 Diabetes Mellitus Pathway Interactive Diagram
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIDDK - National Diabetes Information Clearinghouse (NDIC)
NIDDK - National Diabetes Education Program
NIDDK - The Weight-control Information Network
NIDDK - The NIDDK Reference Collection
The Diabetes Research Institute
American Diabetes Association: Research
The Juvenile Diabetes Research Foundation International (JDRF)
Centers for Disease Control and Prevention - Diabetes Public Health Resource
The Joslin Diabetes Center: Research
OMIM Home Page
OMIM - Type 1 Diabetes/IDDM
OMIM - Type 2 Diabetes/NIDDM
OMIM - Maturity Onset Diabetes of the Young/MODY
OMIM - Permanent Neonatal Diabetes Mellitus
OMIM - Insulin
OMIM - Obesity
OMIM - Abdominal Obesity-Metabolic Syndrome
OMIM - Hypertension
The Human Gene Mutation Database
NCBI - Genes and Disease Home Page
Genes and Disease - Type 1 Diabetes
Genes and Disease - Obesity
Review Articles:
Type 1 Diabetes:
Genetics of type 1A diabetes. Concanno, Rich and Nepom, N Engl J Med. 2009 Apr 16;360(16):1646-54.
Genome-wide association studies in type 1 diabetes. Grant and Hakonarson, Curr Diab Rep. 2009 Apr;9(2):157-63.
An update on preventive and regenerative therapies in diabetes mellitus. Reimann et al, Pharmacol Ther. 2009 Mar;121(3):317-31.
Gene therapy in type 1 diabetes. Bagley et al, Crit Rev Immunol. 2008;28(4):301-24.
Gene-gene interactions in the NOD mouse model of type 1 diabetes. Ridgway et al, Adv Immunol. 2008;100:151-75.
The genetic basis for type 1 diabetes. Mehers and Gillespie, Br Med Bull. 2008;88(1):115-29.
Autoimmune mechanisms in type 1 diabetes. Knip and Siljander, Autoimmun Rev. 2008 Jul;7(7):550-7.
Regulation of type 1 diabetes by NKT cells. Novak et al, Int Rev Immunol. 2007 Jan-Apr;26(1-2):49-72.
Genetics of type 1 diabetes mellitus. Bartsocas and Gerasimidi-Vazeou, Pediatr Endocrinol Rev. 2006 Aug;3 Suppl 3:508-13.
Type 2 Diabetes:
Testosterone in obesity, metabolic syndrome and type 2 diabetes. Stanworth and Jones, Front Horm Res. 2009;37:74-90.
Gene-environment interaction and the metabolic syndrome. Adamo and Tesson, Novartis Found Symp. 2008;293:103-19; discussion 119-27.
Metabolic syndrome: from epidemiology to systems biology. Lusis, Attie and Reue, Nat Rev Genet. 2008 Nov;9(11):819-30.
Type 2 diabetes: where we are today: an overview of disease burden, current treatments, and treatment strategies. Campbell, J Am Pharm Assoc (2003). 2009 Sep-Oct;49 Suppl 1:S3-9.
Fate of the beta-cell in the pathophysiology of type 2 diabetes. Campbell, J Am Pharm Assoc (2003). 2009 Sep-Oct;49 Suppl 1:S10-5.
Genetic dissection of type 2 diabetes. Ridderstråle and Groop, Mol Cell Endocrinol. 2009 Jan 15;297(1-2):10-7.
Agreement among type 2 diabetes linkage studies but a poor correlation with results from genome-wide association studies. Lillioja and Wilton, Diabetologia. 2009 Jun;52(6):1061-74.
Genetic determinants and molecular pathways in the pathogenesis of Type 2 diabetes. Jin and Patti, Clin Sci (Lond). 2009 Jan;116(2):99-111.
Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system. Hunter and Garvey, Am J Med. 1998 Oct;105(4):331-45.
Genetics of type 2 diabetes mellitus. Malecki, Diabetes Res Clin Pract. 2005 Jun;68 Suppl1:S10-21.
The cellular fate of glucose and its relevance in type 2 diabetes. Bouché et al, Endocr Rev. 2004 Oct;25(5):807-30.
Alterations of insulin signaling in type 2 diabetes: a review of the current evidence from humans. Fröjdö, Vidal and Pirola, Biochim Biophys Acta. 2009 Feb;1792(2):83-92.
Novel aspects of the molecular mechanisms controlling insulin secretion. Eliasson et al, J Physiol. 2008 Jul 15;586(14):3313-24.
MicroRNAs in diabetes: tiny players in big disease. Pandey et al, Cell Physiol Biochem. 2009;23(4-6):221-32.
Role of microRNAs in diabetes. Tang, Tang and Ozcan, Biochim Biophys Acta. 2008 Nov;1779(11):697-701.
