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Diabetes Disease Portal – Rat Strain Models
The following tables list strains which have been annotated as models for the Diabetes Disease Portal. For mutant strains, the mutated gene is listed after the strain symbol. Control strains are listed for the respective strain, for given references. The strains listed below are curated with a set of special qualifiers indicating a MODEL of disease, whether induced or spontaneously exhibited. The MODEL qualifier indicates that the curated strain is a rat model developed and used to study human disease. This requires multiple references or a detailed description of disease phenotypes to support the classification.

A more extensive search for strains that exhibit specific diseases, including those not specifically defined as MODELs, can be completed using the Find Models by Disease or Phenotype tool.

Type 1 Diabetes
Strain Affected Gene Control(s) Reference(s)
BBDP/Rhw (MODEL: spontaneous) BBDR/Rhw 2306526; 61032; 1598569
BBDP/RhwMcwi (MODEL: spontaneous) BBDR/RhwMcwi 1598972; 6893459; 41412176; 7794858
BBDP/RhwMcwi (MODEL: treatment) BBDR/RhwMcwi 1598972; 6893459; 41412176; 7794858
BBDP/WorSunn (MODEL: spontaneous) BBDR/WorBrm; ACI.BBDP-(RT1u)(Gimap5)/Sunn 21201284; 1624306; 2303106; 10043114
BBDR/WorBrm (MODEL: induced) 2313207; 1624306
BRAT-Avpdi/BluHsd (MODEL: spontaneous) AVPdi 2314654; 2314661; 632128
KDP/Tky (MODEL:spontaneous) KND/Tky 41412159; 634732
LEW.1AR1-iddm/Ztm (MODEL: spontaneous) 11532657; 41412198
LH/Mav (MODEL: induced) LL/Mav 13441562

Type 2 Diabetes
Strain Affected Gene Control(s) Reference(s)
CD (MODEL: induced) 1354520
CDS.SBN-(D13Rat85-D13Mit4)/Ygl (MODEL:disease progression) 11528530
CDS/Sasz (MODEL: induced) CDR/Sasz 1342468
CDS/Ygl (MODEL: induced) CDR/Ygl; SBN/Ygl 1626640; 8552897
CRDH (MODEL: spontaneous) SHR; WKY 1354689; 724741
GK/KyoSwe (MODEL:spontaneous) 61082
GK/Ox (MODEL) 4889455
OLETF (MODEL: spontaneous) 61072
SDT.ZDF-Leprfa/Jtt (MODEL: spontaneous) Lepr 2314024; 2314025
SDT/Jcl (MODEL: spontaneous) F344/NSlc; Crlj:CD(SD); BN/Seac 628479; 2298688; 631173; 2312348; 19165123
ZDF (MODEL: spontaneous) 68929
ZDF-Leprfa/Drt (MODEL: spontaneous) Lepr 1354693

Didn’t find what you are looking for? Try the Find Models by Disease or Phenotype tool


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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.