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QTL Analysis Tools:
- Genome Annotation Tool
allows the user to input chromosomal location by base pairs or markers
and retrieve a file of ESTs, STS, genes, mRNAs from the region with
position, Unigene IDs, homolog information with direct links to NCBI.
- QTL Matchmaker allows the user to determine if sequences of interest lie within QTL regions in a single species or across species.
- single species
- cross species
Genome Browsers:
- Rat Genome Browser
In addition to the typical sequence tracks, RGD’s Genome Browser
provides QTL tracks and biological tracks for diseases, phenotypes,
pathways, gene function, biological process and cellular component.
- Human Genome Browser
RGD also provides a human genome browser with QTL, disease, pathway,
phenotype, biological process and cellular component tracks.
- GViewer
Gviewer provides users with complete genome view of gene and QTL
annotated to a function, biological process, cellular component,
phenotype, disease, or pathway.
- UCSC Browser
- Ensembl Browser
- NCBI Browser
GO Analysis Tools:
- GOMiner GoMiner leverages the Gene Ontology
to identify the biological processes, functions and components
represented in these lists. Instead of analyzing microarray results
with a gene-by-gene approach, GoMiner classifies the genes into
biologically coherent categories and assesses these categories. The
insights gained through GoMiner can generate hypotheses to guide
additional research.
- Onto-Express , Onto-Compare , Onto-Design , Onto-Translate OE
constructs functional profiles (using Gene Ontology terms) for the
following categories: biochemical function, biological process,
cellular role, cellular component, molecular function and chromosome
location. Statistical significance values are calculated for each
category. Additional tools are provided for microarray data storing and
analysis.
Other Tools:
- Genes2Diseases
is a database of candidate genes for mapped inherited human diseases.
The database is generated using an analysis of relations between
phenotypic features and chemical objects, and from chemical objects to
Gene Ontology protein function terms, based on the whole MEDLINE and
RefSeq databases. Can be used to view all GO terms associated with a
particular genetically inherited disease.
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