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Gene Ontology, Phenotype, Pathway info
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Genes, QTL & Strains related to Disease
Data mining, analysis and visualization
Phenotypes & Traits linked to the genome
Phenotype data, Assays, Husbandry and more
Pathway reports and diagrams
Featured RGD Video Tutorials

Introduction to Biomedical Ontologies #4:  Ontology Term Enrichment Using RatMine

You have a list of genes that might be of interest, but…now what? Click this icon to learn what ontology term enrichment analysis is and how you can use the "widgets" in RatMine to quickly and easily extract enrichment data for your list of genes or proteins.  Or, if you are new to ontologies, start at the beginning of this video series by clicking the Introduction to Biomedical Ontologies Video Series icon below.
 

Introduction to the RGD Phenotypes and Models Portal

In addition to genomic and genetic data, RGD is an excellent source of information about rat strains and their associated physiology, phenotypes and diseases.  Click this icon to learn how to navigate RGD's Phenotypes and Models Portal to find the information you need.

The Introduction to Biomedical Ontologies Video Series

Are you new to the field of Biomedical Ontologies, or just want to become more savvy about their use?  Then this video series is a great place to start.  Click this icon to learn more about ontologies and their annotations.

Click here to access RGD's Rat Community Videos page.  This page includes all of the tutorial videos that RGD has produced, plus other videos of interest to rat researchers.
 Conference Watch
Gordon Conference: Chemistry & Biology of Peptides - Peptides as Signals, BioMaterials and Therapeutics, Ventura Beach Marriott, Ventura, CA, USA - February 19-24, 2012; Application deadline January 22, 2012
Ubiquitin Research in Drug Discovery Conference, Las Vegas, NV, USA - February 27-28, 2012; 10% off registration before January 27, 2012
Systems Biology: Global Regulation of Gene Expression, Cold Spring Harbor, NY, USA - March 20-24, 2012; Abstract Deadline: January 13, 2012
Keystone Symposium: Molecular Basis of Vascular Inflammation and Atherosclerosis, Big Sky, MT, USA - March 25-30, 2012; Late Abstract Deadline: Jan 3, 2012
Gordon Conference: DNA Damage, Mutation & Cancer, Ventura Beach Marriott, Ventura, CA, USA - March 25-30, 2012; Application deadline February 26, 2012
International Society for Biocuration: Biocuration 2012, Washington, DC, USA - April 2-4, 2012; Oral presentation/poster deadline: November 30, 2011
Molecular Pathways in Organ Development & Disease, Cold Spring Harbor, NY, USA - April 17-21, 2012; Abstract Deadline: February 3, 2012
American Physiological Society: Experimental Biology 2012, San Diego, CA, USA - April 21-25, 2012; Late-breaking abstract submissions: November 22, 2011 to February 23, 2012
FASEB: Biology of the Immune System, Capitol Peaks Conference Center, Snowmass Village, CO, USA - June 24-29, 2012; Application deadline: June 8, 2012
Gordon Conference: Enzymes, Coenzymes & Metabolic Pathways, Waterville Valley Resort, Waterville Valley, NH, USA - July 15-20, 2012; Application deadline June 17, 2012
                   
Interleukin-6
Signaling Pathway
RGD has just released the interactive pathway diagram for Interleukin-6 signaling. Click here to explore this important pro-inflammatory pathway.
GBrowse Disease
Tracks
RGD's Rat and Human Genome Browsers now include Disease Tracks where genes, QTLs or strains annotated to disease terms in a given category are displayed. Click here to check it out!
Toll-like Receptor
Signaling Pathway
RGD has released the Toll-like signaling pathway diagram. Click here to explore this first line of defense initiated by the innate immune system.
Virtual Physiological Rat

Congratulations to MCW's Dr. Daniel Beard! The NIH's National Institute of General Medical Sciences just funded a grant to establish a National Center for Systems Biology and create the "Virtual Physiological Rat"--a tool to leverage diverse rat data to model complex diseases. Click here for more information.

Glucose Homeostasis
Pathway Suite Network
Glucose homeostasis relies on a finely-tuned, coordinated network of metabolic, regulatory and signaling pathways. Click here to explore the network of pathway suites involving homeostasis of this essential fuel.
Calendar PDF
Now Available
A high-resolution PDF copy of RGD's 2012 Rat Calendar is available on the RGD FTP site. If you would like a copy of this year's fun collection of rat photos and drawings but aren't close enough to stop by and pick one up, click here to download your copy!
Developmental
Pathway Suite
Several signaling pathways play essential roles in developmental processes and also serve important functions in the adult. Click here to explore this collection of important signaling pathways.
New QTL Report Pages

RGD announces the release of new QTL Report pages. Pages include valuable new data types, and more intuitive organization makes it easier to navigate to the information you need. To explore the new page format, click here.

Hedgehog Signaling
Pathway
RGD announces the release of Hedgehog signaling pathway. Click here to explore this pathway with very important roles in embryogenesis and also in the adult.
Ontology Browser and Report Pages

RGD announces the release of new Ontology Report pages and a new Ontology Browser. New browser functionality facilitates navigation up and down the tree, and better organization of annotations on report pages clarify data presentation. To explore the new page format, click here.

Physiological Pathway
Diagram Tutorial
RGD's Physiological pathway diagrams provide an interactive way to visualize and explore systems-level networks. To help you navigate these, RGD has released a video tutorial outlining the features of the diagrams. Click here to learn more.
Respiratory Disease Portal

RGD announces the release of the Respiratory Disease Portal. Click here to explore genes, QTLs and strains linked to diseases such as asthma, COPD, Cystic Fibrosis and more, as well as associated phenotypes, pathways and biological processes.

Harlan Strain
Cryopreservation
Harlan Laboratories has announced that they will be stopping production of certain strains due to low demand. Click here for more information about which strains are currently targeted and what your alternatives are if you use any of these strains for your research.
 Latest News
    02/07 - RGD releases the Interleukin-6 signaling pathway
    02/06 - Toll-like receptor signaling pathway is now available at RGD.
    02/03 - Physiological Pathway Diagram Tutorial
    01/27 - RGD releases the glucose homeostasis pathway suite network, a suite of pathway suites for glucose homeostasis
    01/26 - RGD releases a developmental pathway suite
    01/16 - Hedgehog signaling pathway diagram now available at RGD
    12/21 - RGD releases new Disease Tracks on rat and human GBrowse
    12/19 - RGD's 2012 Rat Calendar now available for download
    10/25 - RGD releases a "pathway suite network" for balancing inflammatory responses
    10/12 - RGD releases pathways related to inflammation
    9/29 - RGD announces the release the of de novo pyrimidine biosynthetic pathway
    09/14 - Harlan announces strains for cryopreservation
    09/12 - Photos and other artwork needed for RGD's 2012 Rat Calendar
    07/01 - RGD releases the Respiratory Disease Portal
    07/01 - RGD releases three new renin-angiotensin system-related pathway diagrams
    06/02 – RGD releases a new protein kinase C signaling pathway diagram
    05/23 - RGD releases a new Overgo Probe Designer tool
    05/06 – RGD announces the retirement of the MCW BioMart tool
    05/03 - RGD releases a collection of interactive pathway diagrams for the anti-estrogen drugs
    04/20 – Gene type and RefSeq status information added to gene search results
    04/13 – RGD's pathway portal is featured in the new publication by Petri et al in the journal Database
    03/21 - RGD releases steroid hormone-related pathways including Estrogen Signaling and the Steroid Hormone Biosynthesis Pathway Suite
    03/08 - Autophagy pathway diagram now available at RGD