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Strains Help
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| RGD Definition | ||||
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"Rats that are used in a laboratory come from different sources; most of these are derived from Rattus norvegicus. An inbred strain is one whose background can be defined and is named by the nomenclature conventions." Normally the strains are named following the nomenclature guidelines. This is generally a unique, brief symbol made up of upper case, roman letters or a combination of letters and numbers beginning with a letter. RGD is endeavouring to create a comprehensive list of Rat strains in use by the community so that information about strain characteristics and availability can be maintained and made available to the widest audience. We are looking for community support in this effort in the following ways:
Please contact strains@rgd.mcw.edu to submit your strain data. We can send the strain template and the guidelines for completing the template. [ back to top ] |
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| Finding Strain information | ||||
1. Using the General Search The general RGD search available at the top of each page is a quick route to finding strains. This will search Strain symbols and names only. (See General RGD Search help for more information). 2. Using the Strain Search Form - Provides more customizable options Quick Guide
Note: Selecting a 'primary' strain such as BN (no substrain designation) will show the data for BN and all associated substrains of BN in RGD (BN/Cub-lx, BN/SsNHsd, etc). Selecting a strain with a specific substrain designation will show you the data for that strain alone. This is to facilitate comparison of strains and substrain information. Below is a more detailed explanation of each element of the search form, which will allow you greater flexibility to refine your searches. Enter a strain symbol, alias or keyword to search for. The asterisk '*' is an accepted wildcard. Sample keyword searches include Hypertension, Diabetes, cancer, etc. The returned list of hits shows the keyword in the context of the text in the strain record to aid in identification of meaningful hits. Restrict the strain fields searched, multiple selections are allowed, the fields contain information on the following:
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The strain report contains links to information and resources related to this strain, including QTLs mapped using this strain and references containing information about these strains. [ back to top ] |
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| The Strain Report | ||||
| The following fields are present on the Strain report:
The official strain symbol (combination of strain and substrain designations) The official strain symbol The official substrain symbol - typically this is a collection of ILAR lab
codes defining the history of this particular strain. The common full text name for the strain Known labs or companies who can provide this strain to other researchers. Type of strain - inbred,
congenic, consomic,
outbred. Links to other substrains of this strain, or the main strain for this substrain.
These pages often have extra information about a particular strain, especially
the parental strain page (e.g. BN would be the parental strain for the BN/Ssn
substrain). Genotype for standard genetic markers used in the characterization of inbred
strains. The coat color of this strain - e.g. Albino, brown, white. The number of generations that this strain has been inbred at the time the
data was curated. An indication of the number of SSLP markers that have been characterized in
this strain. If present, this data is available via the FTP site (SSLPS_ALLELES
file) and is also integrated into GenomeScanner
for the selection of polymorphic markers between strains. A textual description of notes obtained from the literature on the following
subjects: References curated by the RGD curation team that contain information pertaining
to this strain. [ back to top ] |
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