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Strain Registration

Strain: W-Il2rgem1Hina

Symbol: W-Il2rgem1Hina
Strain: W-Il2rgem1
Substrain: Kyo
RGD ID: 9685757
Citation ID: RRID:RGD_9685757
Ontology ID: RS:0003857
Alleles: Il2rgem1Hina
Also Known As: Wistar-X-SCID; W-Il2rgKO /Hina; NBRP Rat No: 0696; W-Il2rgem1Hina; W-Il2rg^[em1Hina]
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: This strain was generated by electroporation method: introduction of Il2rg gene-targeting vector (PKG promoter-HSV TK, loxp Tk2 promoter-Neor loxp) into ES cells of Wistar rat(Crlj:Wistar)
Coat Color: Albino
Last Known Status: Cryopreserved Embryo (as of 2017-03-27)
Research Usage Immunology
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X66,395,330 - 66,399,026RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X71,165,378 - 71,169,078RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X72,017,856 - 72,021,516RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4X89,342,055 - 89,345,715RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics This strain shows severe combined immunodeficiency (SCID) caused by a 636-bp deletion between Exon7 and Intron8 in the Il2rg gene and knock-in of neomycin resistance gene. This strain can grow normally under SPF condition. 1302502
strain_reproduction Maintained by mating of hemizygous male and heterozygous female. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-27 W-Il2rgem1Hina    W-Il2rgem1Hina    Name updated 68913 APPROVED
2015-05-27 W-Il2rgem1Hina    W-Il2rgem1Hina    Name updated 68913 APPROVED