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Strain Registration

Strain: IER/Ihr

Symbol: IER/Ihr
Strain: IER
Substrain: Ihr
RGD ID: 631285
Citation ID: RRID:RGD_631285
Ontology ID: RS:0000405
Also Known As: IER;IGER;NBRP Rat No: 0291
Type: inbred
Available Source: National BioResource Project for the Rat in Japan
Origination: Institute of Experimental Animals of Shiga University, Medical Science, Ohtsu, Japan
Description: A mutant rat strain which is a useful model for human cataract.
Last Known Status: Live Animals
Research Usage Neurobiology; Ophthalmology





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
IER/IhrRatIER/Ihr  IEA 7241799 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
IER/IhrRatlens clarity trait  EXP 68701 RGD 

Phenotype Values via Phenominer Click to see Annotation Detail View

Related Phenotype Data for Term "IER/Ihr" (RS:0000405)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Disease Annotations     Click to see Annotation Detail View
cataract  (IAGP)


Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Genetic analysis of cataract in Ihara epileptic rat. Yokoyama M, etal., Mamm Genome 2001 Mar;12(3):207-11.

Region

Strain QTL Data
Symbol Name Trait
Lecl1 Lens clarity QTL 1 lens clarity trait   (VT:0001304)    
Lecl2 Lens clarity QTL 2 lens clarity trait   (VT:0001304)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Animals could be divided into early-onset group (EOG) which developed cataract in 4 months and late-onset group (LOG) which developed it in 8 months or more. 68701
strain_life_disease These animals exhibit both cataract and epilepsy phenotypically.F1 animals did not develop cataract, both males and females of the F2 and the backcross developed cataract. 68701

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-16 IER/Ihr    IER/Ihr    Name updated 68913 APPROVED
2012-05-16 IER/Ihr    IER/Ihr    Name updated 68913 APPROVED