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Strain Registration

Strain: SD;DA-Tg(Thy1-APP*)1Dspb

Symbol: SD;DA-Tg(Thy1-APP*)1Dspb
Strain: SD;DA-Tg(Thy1-APP*)1
Substrain: Dspb
RGD ID: 38599241
Citation ID: RRID:RGD_38599241
Ontology ID: RS:0004891
Also Known As: App(Swe/Ind)-Tg1 Dspb; NBRP Rat No: 0896
Type: transgenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Mutant human amyloid beta (APP*) combined Thy1 promoter which is specifically expressed in neurons, was induced to ES cells from DA strain rats, and chimera rats obtained from the ES cells. The F1 rats were backcrossed with Crl:CD (SD) strain rats and F3 rats was deposited to NBRP. The expression levels of mutant human APP mRNA are different among Lines (12>1>14>6).
Last Known Status: Cryopreserved Sperm (as of 2020-09-16)
Research Usage dementia






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP

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