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Strain Registration

Strain: WIC;WDB-Kiss1tm1Nurep

Symbol: WIC;WDB-Kiss1tm1Nurep
Strain: WIC;WDB-Kiss1tm1
Substrain: Nurep
RGD ID: 329848995
Citation ID: RRID:RGD_329848995
Ontology ID: RS:0005273
Also Known As: NBRP Rat No: 0956; WIC;WDB-Kiss1^[tm1Nurep]
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: The kisspeptin gene (Kiss1) is knocked out conditonally by the Cre recombinase. This strain was generated by K.I. Maeda (The University of Tokyo), H. Tsukamura, Y. Uenoyama, N. Inoue (Nagoya University), and M. Hirabayashi (National Institute for Physiological Sciences) for the purpose of producing conditional knockout rats of the Kiss1 gene in the hypothalamus. The targeting vector (loxP, Kiss1[exons 2 and 3], PGK promoter-neo, loxP) was introduced by electroporation targeting the Kiss1 gene in ES cells (WDB/Nips-ES1/Nips). Crossed with and maintained by the Wistar-Imamichi rats (Iar:Wistar-Imamichi, Institute for Animal Reproduction).
Coat Color: white
Last Known Status: Cryopreserved Sperm (as of 2023-06-07)






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP

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