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Strain Registration

Strain: F344-Hrkrh/Kyo

Symbol: F344-Hrkrh/Kyo
Strain: F344-Hrkrh
Substrain: Kyo
Full Name: Hairless Kyoto, Hanako
RGD ID: 2314230
Citation ID: RRID:RGD_2314230
Ontology ID: RS:0001882
Also Known As: F344-hrk/Kyo;NBRP Rat No: 0471; F344-hrk/Kyo; F344-Hrkrh/Kyo; F344-Hr^[krh]/Kyo
Type: mutant
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: A mutant rat showing abnormal skin phenotype was found in the G1 rats produced by ENU mutagenesis (phenotype-driven).
Coat Color: Albino
Last Known Status: Cryopreserved Sperm
Research Usage Dermatology; Urology





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table

Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio

References

References - curated
# Reference Title Reference Citation
1. Kyoto rhino rats derived by ENU mutagenesis undergo congenital hair loss and exhibit focal glomerulosclerosis. Kuramoto T, etal., Exp Anim. 2011;60(1):57-63. doi: 10.1538/expanim.60.57.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Hairless phenotype appears at 4-5 weeks of age. Wrinkled skin. Sebum-filled hair follicle. 1302502
strain_reproduction Male rats show good breeding performance. Females are fertile, but have poor breeding performance. Maintained in heterozygous condition by backcrossing onto F344/NSlc. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-22 F344-Hrkrh/Kyo  Hairless Kyoto, Hanako  F344-HrKrh/Kyo  Hairless Kyoto, Hanako  Symbol updated 68687 APPROVED
2014-03-25 F344-HrKrh/Kyo  Hairless Kyoto, Hanako  F344-HrKrh/Kyo  Hairless Kyoto, Hanako  Symbol updated 68687 APPROVED
2010-10-22 F344-HrKrh/Kyo  Hairless Kyoto, Hanako  F344-hrk/Kyo  Hairless Kyoto, Hanako  Symbol and/or name change 68913 APPROVED
2010-10-22 F344-HrKrh/Kyo  Hairless Kyoto, Hanako  F344-HrKrh/Kyo  Hairless Kyoto, Hanako  Symbol and/or name change 68913 APPROVED