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Strain Registration

Strain: SHRSP.WKY-(D1Rat44-D1Arb21)/Izm

Symbol: SHRSP.WKY-(D1Rat44-D1Arb21)/Izm
Strain: SHRSP.WKY-(D1Rat44-D1Arb21)
Substrain: Izm
RGD ID: 2302106
Citation ID: RRID:RGD_2302106
Ontology ID: RS:0001680
Also Known As: SHRSPwch1.5;SHRSP.WKY-(D1Rat44-D1Arb21)/Izm;NBRP Rat No: 0226; SHRSP.WKY-(D1Rat44-D1Arb21)/Izm
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: SHRSP.WKY-(Klk1-D1Rat116)/Izm was backcrossed with SHRSP/Izm, resulting F1 were intercrossed to obtain F2 recombinant individuals were selected by marker assisted selection
Last Known Status: Cryopreserved Embryo
Research Usage Cardio Hypertension
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81160,283,901 - 191,848,948RGD_MAPPER_PIPELINE
mRatBN7.21150,872,626 - 182,418,476RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01161,493,758 - 199,254,774RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.01167,707,459 - 206,277,202RGD_MAPPER_PIPELINERnor_5.0
RGSC_v3.41153,754,139 - 187,092,492RGD_MAPPER_PIPELINERGSC_v3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Genetic effects of blood pressure quantitative trait Loci on hypertension-related organ damage: evaluation using multiple congenic strains. Ishikawa N, etal., Hypertens Res. 2008 Sep;31(9):1773-9.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D1Rat44)
Rat AssemblyChrPosition (strand)Source
GRCr81160,283,901 - 160,284,012 (+)Marker Load Pipeline
mRatBN7.21150,872,626 - 150,872,737 (+)MAPPER
Rnor_6.01161,493,758 - 161,493,868NCBI
Rnor_5.01167,707,459 - 167,707,569UniSTS
RGSC_v3.41153,754,139 - 153,754,250RGD
RGSC_v3.41153,754,140 - 153,754,250UniSTS
Celera1148,978,583 - 148,978,693UniSTS
RGSC_v3.11153,832,546 - 153,832,656RGD
RH 3.4 Map11161.5UniSTS
RH 3.4 Map11161.5RGD
RH 2.0 Map1770.2RGD
FHH x ACI Map169.91RGD
Cytogenetic Map1q32UniSTS

Flank 2 / 1 (D1Arb21)
Rat AssemblyChrPosition (strand)Source
GRCr81191,848,691 - 191,848,948 (+)Marker Load Pipeline
mRatBN7.21182,418,219 - 182,418,476 (+)MAPPER
Rnor_6.01199,254,518 - 199,254,774NCBI
Rnor_5.01206,276,946 - 206,277,202UniSTS
RGSC_v3.41187,092,235 - 187,092,492RGD
RGSC_v3.41187,092,236 - 187,092,492UniSTS
Celera1180,069,264 - 180,069,520UniSTS
RGSC_v3.11187,242,116 - 187,242,373RGD
FHH x ACI Map185.51RGD
FHH x ACI Map185.51UniSTS
Cytogenetic Map1q36UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Showed low glomerulosclerosis and low albuminuria as compared to other congenics though the blood pressure was high 2302104
strain_life_disease Had higher stroke latency 2302104
strain_phys_biochem blood pressure was not significantly higher than SHRSP/Izm after salt loading 2302104
strain_reproduction Good breeding performance 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-11 SHRSP.WKY-(D1Rat44-D1Arb21)/Izm    SHRSP.WKY-(D1Rat44-D1Arb21)/Izm    Name updated 68913 APPROVED
2012-05-11 SHRSP.WKY-(D1Rat44-D1Arb21)/Izm    SHRSP.WKY-(D1Rat44-D1Arb21)/Izm    Name updated 68913 APPROVED