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Strain Registration

Strain: F344.ACI-Lmx1aqc/Kyo

Symbol: F344.ACI-Lmx1aqc/Kyo
Strain: F344.ACI-Lmx1aqc
Substrain: Kyo
RGD ID: 1549813
Citation ID: RRID:RGD_1549813
Ontology ID: RS:0000303
Alleles: Lmx1a
Also Known As: NBRP No: 0005;F344.ACI-Lmx1aqc/Kyo;F344.ACI-Lmx1aqc/Kyo|\F344.ACI-qc/Kyo;Queue courte rats; F344.ACI-Lmx1aqc/Kyo; F344.ACI-Lmx1a^[qc]/Kyo
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: Institute of Laboratory Animals at Kyoto University, Japan
Description: Congenic strain created by backcrosses between ACI/Pas and F344/NSlc strains. The short-tail mutation, “queue courte” in French (with qc as a symbol), occurred spontaneously in 1994, in the ACI/Pas inbred strain of rat maintained at the Institute Pasteur (Paris, France), and was kept segregating in this stock. Since importation into the Institute of Laboratory Animals at Kyoto University, it has been maintained as a congenic strain F344.ACI-qc using F344/NSlc as an inbred partner.
Coat Color: Albino
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2020-11-12)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81379,009,379 - 86,178,819RGD_MAPPER_PIPELINE
mRatBN7.21376,476,229 - 83,646,358RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01382,428,914 - 89,598,805RGD_MAPPER_PIPELINERnor_6.0
Rnor_5.01387,308,435 - 94,225,670RGD_MAPPER_PIPELINERnor_5.0
RGSC_v3.41379,886,614 - 87,116,372RGD_MAPPER_PIPELINERGSC_v3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Mutation at the Lmx1a locus provokes aberrant brain development in the rat. Kuwamura M, etal., Brain Res Dev Brain Res 2005 Mar 31;155(2):99-106.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (Selp)
Rat AssemblyChrPosition (strand)Source
GRCr81379,009,379 - 79,044,994 (+)NCBI
GRCr8 Ensembl1379,009,475 - 79,044,987 (+)Ensembl
mRatBN7.21376,476,229 - 76,511,846 (+)NCBI
mRatBN7.2 Ensembl1376,476,295 - 76,511,845 (+)Ensembl
UTH_Rnor_SHR_Utx1379,094,917 - 79,130,437 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01380,398,945 - 80,434,427 (+)NCBI
UTH_Rnor_WKY_Bbb_1.01377,653,541 - 77,689,020 (+)NCBI
Rnor_6.01382,428,914 - 82,464,629 (+)NCBI
Rnor_6.0 Ensembl1382,429,063 - 82,464,628 (+)Ensembl
Rnor_5.01387,308,435 - 87,344,164 (+)NCBI
RGSC_v3.41379,886,614 - 79,922,180 (+)NCBI
Celera1376,209,805 - 76,244,685 (+)NCBI
RGSC_v3.11379,910,278 - 79,936,368 (+)NCBI
RH 3.4 Map13482.6RGD
Cytogenetic Map13q23NCBI

Flank 2 / 1 (Apoa2)
Rat AssemblyChrPosition (strand)Source
GRCr81386,176,767 - 86,178,819 (+)NCBI
GRCr8 Ensembl1386,174,741 - 86,179,410 (+)Ensembl
mRatBN7.21383,644,460 - 83,646,358 (+)NCBI
mRatBN7.2 Ensembl1383,644,470 - 83,646,355 (+)Ensembl
UTH_Rnor_SHR_Utx1386,150,563 - 86,152,200 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01387,548,803 - 87,550,440 (+)NCBI
UTH_Rnor_WKY_Bbb_1.01384,780,423 - 84,782,059 (+)NCBI
Rnor_6.01389,596,872 - 89,598,805 (+)NCBI
Rnor_6.0 Ensembl1389,597,138 - 89,598,802 (+)Ensembl
Rnor_5.01394,223,741 - 94,225,670 (+)NCBI
RGSC_v3.41387,114,734 - 87,116,372 (+)NCBI
Celera1383,275,901 - 83,277,538 (+)NCBI
RGSC_v3.11387,303,617 - 87,305,256 (+)NCBI
Cytogenetic Map13q24NCBI

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_anatomy Congenic strain has a short tail. 1549451
strain_anatomy Congenic strain demonstrates hypoplasia of the cerebellum and hippocampus and maldevelopment of the choroid plexus and corpus callosum. 1549451
strain_behavior Congenic strain shows neurological defects and abnormal behavior. 1549451

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-04 F344.ACI-Lmx1aqc/Kyo    F344.ACI-Lmx1aqc/Kyo    Name updated 68913 APPROVED
2012-05-04 F344.ACI-Lmx1aqc/Kyo    F344.ACI-Lmx1aqc/Kyo    Name updated 68913 APPROVED