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Strain Registration

Strain: F344/Stm

Symbol: F344/Stm
Strain: F344
Substrain: Stm
RGD ID: 1302686
Citation ID: RRID:RGD_1302686
Ontology ID: RS:0000428
Also Known As: NBRP Rat No: 0140; MDC-01-73
Type: inbred
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Derived from F344/DuCrlj rats that were purchased from Charles River Kanagawa, Japan. These are maintained by brother and sister mating.
Inbred Generations: F23
Last Known Status: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm
Research Usage Diabetes Obesity; Cancer





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table

Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio

References

References - curated
# Reference Title Reference Citation
1. Identification of QTLs involved in the development of amygdala kindling in the rat. Hashimoto R, etal., Exp Anim. 2013;62(3):181-7.
2. Propylnitrosourea-induced T-lymphomas in LEXF RI strains of rats: genetic analysis. Lu LM, etal., Br J Cancer 1999 May;80(5-6):855-61.
3. A set of highly informative rat simple sequence length polymorphism (SSLP) markers and genetically defined rat strains. Mashimo T, etal., BMC Genet. 2006 Apr 4;7:19.
4. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
5. RGD Strain RSO annotation pipeline RGD Automated Pipelines
6. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
7. The LEXF: a new set of rat recombinant inbred strains between LE/Stm and F344. Shisa H, etal., Mamm Genome 1997 May;8(5):324-7.

Region

Strain Samples in RGD with Damaging Variants (Polyphen)
AssemblySample 
Rnor_5.0 F344/Stm (KyushuU) View Damaging Variants
Rnor_6.0 F344/Stm (2019) View Damaging Variants
mRatBN7.2 F344/Stm (2019) View Damaging Variants


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other A BAC library for this strain is available from the RIKEN BioResource Center. 2292911
strain_reproduction Good breeding performance. 628402

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-09 F344/Stm    F344/Stm    Name updated 68913 APPROVED
2012-05-09 F344/Stm    F344/Stm    Name updated 68913 APPROVED