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Summary
Mutant Strains
Annotation
Phenotype Values via
References
References - curated
Additional Information
RGD Curation Notes
Nomenclature History
Strain Registration
General
Strain: KHR/Kyo
Symbol:
KHR/Kyo
Strain:
KHR
Substrain:
Kyo
Full Name:
kaken hairless rat
RGD ID:
1302639
Citation ID:
RRID:RGD_1302639
Ontology ID:
RS:0000415
Alleles:
Oca2
Also Known As:
MDC-02-12; NBRP Rat No: 0007
Type:
mutant
Available Source:
National BioResource Project for the Rat in Japan
Origination:
National BioResource Project for the Rat in Japan
Description:
Kaken hairless rat were detected by Kimura from Gunn
Coat Color:
albino
Inbred Generations:
F67
Last Known Status:
Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2024-09-24)
Research Usage
Dermatology
Position
Rat Assembly
Chr
Position (strand)
Source
JBrowse
GRCr8
1
116,252,026 - 116,581,838
RGD_MAPPER_PIPELINE
mRatBN7.2
1
107,116,278 - 107,446,093
RGD_MAPPER_PIPELINE
mRatBN7.2
Rnor_6.0
1
114,661,970 - 114,987,433
RGD_MAPPER_PIPELINE
Rnor6.0
Rnor_5.0
1
115,683,593 - 115,991,040
RGD_MAPPER_PIPELINE
Rnor5.0
Mutant Strains
KHR/Kyo-/+
KHR/Kyo-/-
Annotation
Click to see Annotation Summary View
Phenotype Values via Phenominer
Click to see Annotation Summary View
Related Phenotype Data for Term "KHR/Kyo" (RS:0000415)
Rat Strains:
KHR/Kyo
Clinical Measurements:
activated partial thromboplastin time
blood band neutrophil count to total leukocyte count ratio
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood hemoglobin level
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
blood segmented neutrophil count to total leukocyte count ratio
body temperature
body weight
both adrenal glands weight to body weight ratio
both adrenal glands wet weight
both kidneys wet weight
both kidneys wet weight as percentage of body weight
both testes wet weight
both testes wet weight to body weight ratio
brain weight to body weight ratio
brain wet weight
heart rate
heart weight to body weight ratio
heart wet weight
hematocrit
liver weight as percentage of body weight
liver wet weight
lung weight to body weight ratio
lung wet weight
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
mean corpuscular volume
non-specified leukocyte count to total leukocyte count ratio
plasma alanine aminotransferase activity level
plasma albumin level
plasma albumin to plasma total protein ratio
plasma alkaline phosphatase activity level
plasma aspartate aminotransferase activity level
plasma chloride level
plasma creatinine level
plasma glucose level
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
plasma phosphate level
plasma potassium level
plasma sodium level
plasma total bilirubin level
plasma total cholesterol level
plasma total protein level
plasma triglyceride level
plasma urea nitrogen level
platelet count
prothrombin time
red blood cell count
spleen weight to body weight ratio
spleen wet weight
systolic blood pressure
timed urine volume
timed urine volume to body weight ratio
total plasma calcium level
urine chloride excretion rate to body weight ratio
urine chloride level
urine potassium excretion rate to body weight ratio
urine potassium level
urine sodium excretion rate to body weight ratio
urine sodium level
white blood cell count
Experimental Conditions:
0.9% sodium chloride solution
fasting
specific pathogen-free condition
Measurement Methods:
automated blood electrolyte analysis
automated cell/particle size/count analysis method
automated coagulometer method
automated differential white blood cell count test
automated plasma albumin analysis
automated plasma analysis
automated plasma creatinine analysis
automated plasma protein analysis
automated plasma total protein analysis
automated urine analysis
digital rectal thermometry
metabolic cage urine volume measurement method
Shimadzu electronic balance post excision weight measurement
tail cuff photoplethysmography
whole body digital scale
Phenotype Values via PhenoMiner
Click to see Annotation Summary View
10
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All Rows
Options:
View chart
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Download data table
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View expanded data table
Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio
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References
References - curated
1 to 3 of 3 rows
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#
Reference Title
Reference Citation
1.
Strains registered by the National Bio Resource Project for the Rat in Japan
Personal Communication with NBRP
2.
RGD Strain RSO annotation pipeline
RGD Automated Pipelines
3.
SNP and haplotype mapping for genetic analysis in the rat.
Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
1 to 3 of 3 rows
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Region
Additional Information
RGD Curation Notes
Note Type
Note
Reference
strain_characteristics
This strain has deletion mutation in
Oca2
, pink-eyed dilution. A 80-kb deletion was identified in the region containing five basic keratin (
krt
) genes
1302502
strain_reproduction
Heterozygous female and homozygous male are mated.
1302502
Nomenclature History
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2012-05-04
KHR/Kyo
kaken hairless rat
KHR/Kyo
kaken hairless rat
Name updated
68913
APPROVED