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Strain Registration

Strain: LE-Tg(ChAT-cre)5.1DeisRrrc

Symbol: LE-Tg(ChAT-cre)5.1DeisRrrc
Strain: LE-Tg(ChAT-cre)5.1
Substrain: DeisRrrc
RGD ID: 10401204
Citation ID: RRID:RRRC_00658
Ontology ID: RS:0004039
Also Known As: LE-Tg(ChAT-cre)5.1Deis
Type: transgenic
Available Source: Rat Resource and Research Center
Origination: Rat Resource and Research Center
Description: Cre gene was introduced immediately before the ATG of the mouse choline acetyltransferase (Chat) gene in BAC RP23-246B12. This strain is estimated to carry 6 copies of the transgene at the integration site.
Coat Color: Black hooded
Last Known Status: Live Animals; Cryopreserved Sperm (as of 2017-05-31)






References

References - curated
# Reference Title Reference Citation
1. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Witten IB, etal., Neuron. 2011 Dec 8;72(5):721-33. doi: 10.1016/j.neuron.2011.10.028.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other Can be used to selectively target cholinergic neurons in rats 2292495
strain_reproduction Transgene positive animal mated to outbred Long Evans animal. Use hemizygous transgene positive animals for experiments. 2292495
strain_reproduction Litter size:11-15; Weaning Age: 3 weeks 2292495

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-12-05 LE-Tg(ChAT-cre)5.1DeisRrrc    LE-Tg(ChAT-cre)5.1Deis    Symbol and/or name change 68913 APPROVED
2017-05-31 LE-Tg(ChAT-cre)5.1Deis    LE-Tg(ChAT-Cre)5.1Deis    Symbol updated 68687 APPROVED
2017-05-31 LE-Tg(ChAT-cre)5.1Deis    LE-Tg(ChAT-Cre)5.1Deis    Symbol updated 68687 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00658 RGD