Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Strain Registration

Strain: LEW-Pkd1em2Mcwi

Symbol: LEW-Pkd1em2Mcwi
Strain: LEW-Pkd1em2
Substrain: Mcwi
RGD ID: 10054430
Citation ID: RRID:RGD_10054430
Ontology ID: RS:0004002
Alleles: Pkd1em2Mcwi
Also Known As: LEW-Pkd1em2Mcwi; LEW-Pkd1^[em2Mcwi]
Type: mutant
Available Source: Contact MCW rat distribution at mcwcustomrats@mcw.edu
Origination: MCW Gene Editing Rat Resource Center
Description: CRISPR/Cas9 system was used to introduce a mutation in the Pkd1 gene of LEW/NCrl rat embryos. The resulting mutation is a 8-bp deletion in the Pkd1 gene.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,573,779 - 13,621,138RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01013,914,057 - 13,962,008RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01013,769,504 - 13,769,511RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41013,801,445 - 13,848,212RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Data registered by Dr. Melinda Dwinell’s group Personal communication between Dr. Melinda Dwinell’s group and the RGD curators

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Pkd1em2Mcwi-var1 chr10 13769504 13769511 CCGCTTTA - deletion Rnor_5.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 LEW-Pkd1em2Mcwi    LEW-Pkd1em2Mcwi    Symbol updated 68687 APPROVED
2016-03-16 LEW-Pkd1em2Mcwi    LEW-Pkd1em2Mcwi    Name updated 68913 APPROVED
2016-03-16 LEW-Pkd1em2Mcwi    LEW-Pkd1em2Mcwi    Symbol updated 68687 APPROVED
2016-03-16 LEW-Pkd1em2Mcwi    LEW-Pkd1em2Mcwi    Name updated 68913 APPROVED