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Strain Registration

Strain: MSHRSP/Kpo

Symbol: MSHRSP/Kpo
Strain: MSHRSP
Substrain: Kpo
RGD ID: 10045578
Citation ID: RRID:RGD_10045578
Ontology ID: RS:0003924
Also Known As: M-SHRSP A3-T-B/Kpo; NBRP Rat No: 0733
Type: inbred
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Okamoto et al. found that a few rats developed higher blood pressure (over 230 mmHg) at 10 weeks old. They selected SHRSP rats that show severe hypertension from young age and M-SHRSP (malignant or precocious SHRSP) rat was established in 1985.
Coat Color: Albino
Inbred Generations: F183
Last Known Status: Cryopreserved Embryo
Research Usage Cardio-Hypertension






References

References - curated
# Reference Title Reference Citation
1. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Life expectancy of this strain is a half of SHRSP rat (male: average 90 days, female: average 120 days). This strain develop stroke symptoms earlier than SHRSP rat and the incidence of hypertensive cerebrovascular lesion is over 95%. Small or petechial hemorrhage is frequently observed in the base of the brain. 1302502
strain_reproduction Sib mating 1302502