Strain Report - Rat Genome Database

Strain Report - Rat Genome Database

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Strain Registration

General

Strain: MNR/N
Symbol:	MNR/N
Strain:	MNR
Substrain:	N
Full Name:	Maudsely non-reactive
RGD ID:	10026
Citation ID:	RRID:RRRC_00174
Ontology ID:	RS:0000583
Type:	inbred
Available Source:	Not Available
Origination:	NIH Animal Genetic Resource
Description:	To N 1964 at F18+? from Maas. Developed by Broadhurst, 1954, from a commercial stock, with selection for low defecation response in an open field. A number of parallel sublines are in existence; these differ at least at the agouti and the major histocompatibility loci.
Genetic Markers:	A,B,c,h.
Coat Color:	Albino.
Inbred Generations:	F79+?.
Last Known Status:	Extinct

Annotation Click to see Annotation Detail View

References

References - curated

#	Reference Title	Reference Citation
1.	Inbred Strains	Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
2.	Update to previous Strain Data	Festing, MFW, Personal Communication Update, Feb-2000
3.	NIH Rat Strain Data	NIH Rat Strain Data
4.	Data registered by the Rat Resource & Research Center	Personal Communication with Rat Resource & Research Center
5.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_behavior	The strain is widely used in behaviour research, and characteristics have been described by Harrington (1971a,b, 1972, 1979a-i). Long latency to emerge into a familiar (11/12) and novel (12/12) environment in females (Harrington 1971a). Low open field defecation (12/12 males, 11/12 to 9/12 depending on subline in females) (Harrington 1972). High wheel activity (1/12) (Harrington 1971b). Low open-field defecation (8/8) in hybrid offspring (Rick and Fulker 1972).	1004
strain_behavior	The strain is widely used in behaviour research, and characteristics have been described by Harrington (1971a,b, 1972, 1979a-i). Long latency to emerge into a familiar (11/12) and novel (12/12) environment in females (Harrington 1971a). Low open field defecation (12/12 males, 11/12 to 9/12 depending on subline in females) (Harrington 1972). High wheel activity (1/12) (Harrington 1971b). Low open-field defecation (8/8) in hybrid offspring (Rick and Fulker 1972).	634612
strain_characteristics	Other papers comparing MR and MNR or MR and MNRA include Commissaris et al (1992), Abel et al, (1992), Sara et al, (1993), Buda et al, (1994), Sara et al, (1994), Verbanac et al, (1993)	1004
strain_characteristics	Other papers comparing MR and MNR or MR and MNRA include Commissaris et al (1992), Abel et al, (1992), Sara et al, (1993), Buda et al, (1994), Sara et al, (1994), Verbanac et al, (1993)	634612
strain_phys_biochem	Low blood pressure (23/23), reaching 118_1.1 (SEM) mmHg at 10 weeks of age (Tanase et al 1982). Low 10-week body weight in males (1/23) (Tanase et al 1982).	1004
strain_phys_biochem	Low blood pressure (23/23), reaching 118_1.1 (SEM) mmHg at 10 weeks of age (Tanase et al 1982). Low 10-week body weight in males (1/23) (Tanase et al 1982).	634612
strain_reproduction	Good breeding performance (3/12) and large litter size (3/12) (Hansen et al 1973). See also MR. An extensive review of the differences between MR and MNR is given by Broadhurst (1975).	1004
strain_reproduction	Good breeding performance (3/12) and large litter size (3/12) (Hansen et al 1973). See also MR. An extensive review of the differences between MR and MNR is given by Broadhurst (1975).	634612

External Database Links

Database	Acc Id	Source(s)
RRRC	RRRC:00174	RGD