Tox2 (TOX high mobility group box family member 2) - Rat Genome Database

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Gene: Tox2 (TOX high mobility group box family member 2) Rattus norvegicus
Analyze
Symbol: Tox2
Name: TOX high mobility group box family member 2
RGD ID: 735184
Description: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in female gonad development; positive regulation of transcription by RNA polymerase II; and response to gonadotropin. Predicted to be active in nucleus. Orthologous to human TOX2 (TOX high mobility group box family member 2); INTERACTS WITH 4,4'-sulfonyldiphenol; alpha-Zearalanol; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GCX-1; Gcx1; granulosa cell HMG box protein 1; granulosa cell HMG-box protein 1; granulosa cell HMG-box protein-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83172,272,718 - 172,400,235 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3172,272,736 - 172,400,233 (+)EnsemblGRCr8
mRatBN7.23151,853,294 - 151,980,086 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3151,853,294 - 151,980,749 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3155,660,818 - 155,787,503 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03164,159,772 - 164,286,456 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03161,903,840 - 162,030,363 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03159,569,329 - 159,694,756 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3159,569,363 - 159,694,756 (+)Ensemblrn6Rnor6.0
Rnor_5.03165,761,081 - 165,890,364 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43154,075,542 - 154,205,141 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3150,510,051 - 150,636,666 (+)NCBICelera
RGSC_v3.13153,981,577 - 154,111,177 (+)NCBI
Cytogenetic Map3q42NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells. Kajitani T, etal., Endocrinology 2004 May;145(5):2307-18. Epub 2004 Feb 05.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:25352127  


Genomics

Comparative Map Data
Tox2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83172,272,718 - 172,400,235 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3172,272,736 - 172,400,233 (+)EnsemblGRCr8
mRatBN7.23151,853,294 - 151,980,086 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3151,853,294 - 151,980,749 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3155,660,818 - 155,787,503 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03164,159,772 - 164,286,456 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03161,903,840 - 162,030,363 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03159,569,329 - 159,694,756 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3159,569,363 - 159,694,756 (+)Ensemblrn6Rnor6.0
Rnor_5.03165,761,081 - 165,890,364 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43154,075,542 - 154,205,141 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3150,510,051 - 150,636,666 (+)NCBICelera
RGSC_v3.13153,981,577 - 154,111,177 (+)NCBI
Cytogenetic Map3q42NCBI
TOX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382043,914,852 - 44,069,616 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2043,914,844 - 44,069,616 (+)Ensemblhg38GRCh38
GRCh372042,543,492 - 42,698,256 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362041,976,906 - 42,131,670 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342041,978,220 - 42,131,666NCBI
Celera2039,250,919 - 39,406,866 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2039,278,939 - 39,434,941 (+)NCBIHuRef
CHM1_12042,447,111 - 42,601,501 (+)NCBICHM1_1
T2T-CHM13v2.02045,648,018 - 45,804,192 (+)NCBIT2T-CHM13v2.0
Tox2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392163,045,047 - 163,166,092 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2163,045,045 - 163,166,090 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382163,203,058 - 163,324,172 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2163,203,125 - 163,324,170 (+)Ensemblmm10GRCm38
MGSCv372163,051,190 - 163,148,838 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362162,895,900 - 163,014,543 (+)NCBIMGSCv36mm8
Celera2169,172,013 - 169,272,833 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map284.14NCBI
Tox2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544513,208,413 - 13,314,827 (-)Ensembl
ChiLan1.0NW_00495544513,210,606 - 13,343,344 (-)NCBIChiLan1.0ChiLan1.0
TOX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22149,645,134 - 49,802,367 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12049,638,242 - 49,795,474 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02040,242,893 - 40,400,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12041,336,616 - 41,493,142 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2041,336,612 - 41,493,142 (+)EnsemblpanPan2panpan1.1
TOX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12431,523,323 - 31,656,361 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2431,522,798 - 31,656,373 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2431,165,908 - 31,298,502 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02432,230,525 - 32,363,312 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2432,230,481 - 32,363,312 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12431,494,246 - 31,626,728 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02431,606,016 - 31,738,798 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02432,148,382 - 32,281,033 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640180,531,824 - 180,659,438 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365302,646,774 - 2,727,618 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365302,646,783 - 2,774,162 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1746,433,025 - 46,577,072 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11746,433,005 - 46,577,076 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21751,986,557 - 52,002,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TOX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1219,747,852 - 19,902,892 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl219,747,857 - 19,902,828 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605068,423,983 - 68,579,003 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tox2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479010,339,858 - 10,467,837 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479010,339,928 - 10,467,855 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tox2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15154,663,143 - 154,787,094 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:334
Count of miRNA genes:206
Interacting mature miRNAs:238
Transcripts:ENSRNOT00000064159
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3166376089177728348Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161799493176036425Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 66 156 85 87 56 89 56 6 325 184 9 139 62 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000064159   ⟹   ENSRNOP00000061248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3172,272,736 - 172,400,233 (+)Ensembl
mRatBN7.2 Ensembl3151,875,774 - 151,979,990 (+)Ensembl
Rnor_6.0 Ensembl3159,569,363 - 159,694,756 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113439   ⟹   ENSRNOP00000080355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3172,346,542 - 172,400,233 (+)Ensembl
mRatBN7.2 Ensembl3151,927,058 - 151,979,990 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119983   ⟹   ENSRNOP00000085812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3172,272,736 - 172,398,961 (+)Ensembl
mRatBN7.2 Ensembl3151,853,294 - 151,980,749 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000124880   ⟹   ENSRNOP00000101723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3172,274,007 - 172,400,233 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139569   ⟹   ENSRNOP00000109615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3172,316,233 - 172,400,233 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000160364   ⟹   ENSRNOP00000103545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3172,315,796 - 172,400,233 (+)Ensembl
RefSeq Acc Id: NM_199392   ⟹   NP_955424
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,272,785 - 172,399,469 (+)NCBI
mRatBN7.23151,853,294 - 151,979,990 (+)NCBI
Rnor_6.03159,569,363 - 159,694,756 (+)NCBI
Rnor_5.03165,761,081 - 165,890,364 (+)NCBI
RGSC_v3.43154,075,542 - 154,205,141 (+)RGD
Celera3150,510,051 - 150,636,666 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235578   ⟹   XP_006235640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,272,718 - 172,400,235 (+)NCBI
mRatBN7.23151,853,327 - 151,979,319 (+)NCBI
Rnor_6.03159,569,329 - 159,694,341 (+)NCBI
Rnor_5.03165,761,081 - 165,890,364 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591794   ⟹   XP_017447283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,274,904 - 172,400,235 (+)NCBI
mRatBN7.23151,855,409 - 151,979,549 (+)NCBI
Rnor_6.03159,571,476 - 159,694,414 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105118   ⟹   XP_038961046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,272,975 - 172,400,235 (+)NCBI
mRatBN7.23151,853,581 - 151,979,549 (+)NCBI
RefSeq Acc Id: XM_039105119   ⟹   XP_038961047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,275,084 - 172,400,235 (+)NCBI
mRatBN7.23151,869,922 - 151,979,549 (+)NCBI
RefSeq Acc Id: XM_039105120   ⟹   XP_038961048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,314,282 - 172,400,235 (+)NCBI
mRatBN7.23151,895,425 - 151,979,549 (+)NCBI
RefSeq Acc Id: XM_039105121   ⟹   XP_038961049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,272,962 - 172,400,235 (+)NCBI
mRatBN7.23151,854,700 - 151,980,086 (+)NCBI
RefSeq Acc Id: XM_063283868   ⟹   XP_063139938
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83172,272,974 - 172,400,235 (+)NCBI
RefSeq Acc Id: NP_955424   ⟸   NM_199392
- UniProtKB: A0A8I6G6H2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235640   ⟸   XM_006235578
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A4F5 (UniProtKB/TrEMBL),   A0A8I6G6H2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447283   ⟸   XM_017591794
- Peptide Label: isoform X2
- UniProtKB: Q76IQ7 (UniProtKB/Swiss-Prot),   A0A8I6G6H2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061248   ⟸   ENSRNOT00000064159
RefSeq Acc Id: XP_038961046   ⟸   XM_039105118
- Peptide Label: isoform X2
- UniProtKB: Q76IQ7 (UniProtKB/Swiss-Prot),   A0A8I6G6H2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961049   ⟸   XM_039105121
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038961047   ⟸   XM_039105119
- Peptide Label: isoform X2
- UniProtKB: Q76IQ7 (UniProtKB/Swiss-Prot),   A0A8I6G6H2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961048   ⟸   XM_039105120
- Peptide Label: isoform X2
- UniProtKB: Q76IQ7 (UniProtKB/Swiss-Prot),   A0A8I6G6H2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085812   ⟸   ENSRNOT00000119983
Ensembl Acc Id: ENSRNOP00000080355   ⟸   ENSRNOT00000113439
RefSeq Acc Id: XP_063139938   ⟸   XM_063283868
- Peptide Label: isoform X3
- UniProtKB: A0A8I6G6H2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000103545   ⟸   ENSRNOT00000160364
Ensembl Acc Id: ENSRNOP00000109615   ⟸   ENSRNOT00000139569
Ensembl Acc Id: ENSRNOP00000101723   ⟸   ENSRNOT00000124880
Protein Domains
HMG box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76IQ7-F1-model_v2 AlphaFold Q76IQ7 1-473 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692633
Promoter ID:EPDNEW_R3156
Type:single initiation site
Name:Tox2_1
Description:TOX high mobility group box family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03159,569,323 - 159,569,383EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735184 AgrOrtholog
BioCyc Gene G2FUF-46919 BioCyc
Ensembl Genes ENSRNOG00000008146 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000064159 ENTREZGENE
  ENSRNOT00000139569 ENTREZGENE
Gene3D-CATH 1.10.30.10 UniProtKB/Swiss-Prot
InterPro HMG_box_dom UniProtKB/Swiss-Prot
  HMG_box_dom_sf UniProtKB/Swiss-Prot
  TOX_HMG-box_domain UniProtKB/Swiss-Prot
KEGG Report rno:311615 UniProtKB/Swiss-Prot
NCBI Gene 311615 ENTREZGENE
PANTHER AGAP000281-PA UniProtKB/Swiss-Prot
  TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 2 UniProtKB/Swiss-Prot
Pfam HMG_box UniProtKB/Swiss-Prot
PhenoGen Tox2 PhenoGen
PRINTS HIGHMOBLTY12 UniProtKB/Swiss-Prot
PROSITE HMG_BOX_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008146 RatGTEx
SMART HMG UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47095 UniProtKB/Swiss-Prot
UniProt A0A8I6A4F5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G6H2 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LC33_RAT UniProtKB/TrEMBL
  A0ABK0LJI7_RAT UniProtKB/TrEMBL
  A0ABK0LW91_RAT UniProtKB/TrEMBL
  F1M8E3_RAT UniProtKB/TrEMBL
  Q76IQ7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Tox2  TOX high mobility group box family member 2  Gcx1  granulosa cell HMG-box protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Gcx1  granulosa cell HMG-box protein 1  GCX-1  granulosa cell HMG-box protein-1  Symbol and Name updated 1299863 APPROVED