Tubb4b (tubulin, beta 4B class IVb) - Rat Genome Database

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Gene: Tubb4b (tubulin, beta 4B class IVb) Rattus norvegicus
Analyze
Symbol: Tubb4b
Name: tubulin, beta 4B class IVb
RGD ID: 735101
Description: Predicted to enable GTP binding activity and double-stranded RNA binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in flagellated sperm motility; microtubule cytoskeleton organization; and mitotic cell cycle. Predicted to be located in axonemal microtubule. Predicted to be active in cytoplasm; microtubule; and sperm flagellum. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness. Orthologous to human TUBB4B (tubulin beta 4B class IVb); INTERACTS WITH (+)-schisandrin B; (S)-colchicine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC73008; Tubb2; Tubb2c; tubulin beta-2C chain; tubulin beta-4B chain; tubulin, beta 2C; tubulin, beta, 2; tubulin, beta2-like; Unknown (protein for MGC:73008)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,435,999 - 28,438,455 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl328,435,148 - 28,439,719 (-)EnsemblGRCr8
mRatBN7.238,037,838 - 8,040,294 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,037,799 - 8,040,296 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,142,521 - 11,144,977 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,728,750 - 19,731,206 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,918,593 - 17,921,049 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,441,585 - 2,444,369 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,441,733 - 2,444,281 (-)Ensemblrn6Rnor6.0
Rnor_5.032,422,868 - 2,425,649 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.433,387,050 - 3,389,500 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera32,864,558 - 2,867,008 (-)NCBICelera
RGSC_v3.133,387,049 - 3,389,500 (-)NCBI
Cytogenetic Map3p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-colchicine  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
7,12-dimethyltetraphene  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
azathioprine  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP)
bromobenzene  (EXP)
buspirone  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
diallyl trisulfide  (ISO)
diazinon  (EXP)
dibenzo[a,l]pyrene  (ISO)
diclofenac  (ISO)
dioxygen  (ISO)
dopamine  (EXP)
doxorubicin  (ISO)
enniatin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenoldopam  (EXP)
fenvalerate  (EXP)
finasteride  (EXP)
flutamide  (EXP)
furan  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
indometacin  (EXP)
isoflavones  (EXP)
ivermectin  (ISO)
lead(II) chloride  (ISO)
leflunomide  (ISO)
levofloxacin  (EXP)
Licochalcone B  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
microcystin-LR  (EXP)
N-(6-acetamidohexyl)acetamide  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nitrates  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP,ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
propiconazole  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP,ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP,ISO)
trovafloxacin  (EXP,ISO)
tungsten  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vincaleukoblastine  (EXP)
vincristine  (EXP,ISO)
vitamin E  (ISO)
zearalenone  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axonemal microtubule  (IEA,ISO)
cytoplasm  (IBA)
cytoskeleton  (IEA)
microtubule  (IBA,IEA,ISO)
sperm flagellum  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Information Derived from GenBank Report RGD, Sept. 2003
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:11487543   PMID:15489334   PMID:17634366   PMID:19666135   PMID:20131911   PMID:20458337   PMID:21266579   PMID:21525035   PMID:21630459   PMID:22120110   PMID:22871113   PMID:23106098  
PMID:23376485   PMID:23533145   PMID:23979707   PMID:24625528   PMID:24769233   PMID:25002582   PMID:25763846   PMID:25931508   PMID:26316108   PMID:29476059   PMID:31904090   PMID:35352799  


Genomics

Comparative Map Data
Tubb4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8328,435,999 - 28,438,455 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl328,435,148 - 28,439,719 (-)EnsemblGRCr8
mRatBN7.238,037,838 - 8,040,294 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl38,037,799 - 8,040,296 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx311,142,521 - 11,144,977 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0319,728,750 - 19,731,206 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0317,918,593 - 17,921,049 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.032,441,585 - 2,444,369 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl32,441,733 - 2,444,281 (-)Ensemblrn6Rnor6.0
Rnor_5.032,422,868 - 2,425,649 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.433,387,050 - 3,389,500 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera32,864,558 - 2,867,008 (-)NCBICelera
RGSC_v3.133,387,049 - 3,389,500 (-)NCBI
Cytogenetic Map3p13NCBI
TUBB4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389137,241,287 - 137,243,707 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9137,241,287 - 137,243,707 (+)Ensemblhg38GRCh38
GRCh379140,135,739 - 140,138,159 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369139,255,532 - 139,257,980 (+)NCBIBuild 36Build 36hg18NCBI36
Celera9110,651,151 - 110,653,744 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,595,024 - 109,597,472 (+)NCBIHuRef
CHM1_19140,284,445 - 140,286,893 (+)NCBICHM1_1
T2T-CHM13v2.09149,478,956 - 149,481,376 (+)NCBIT2T-CHM13v2.0
Tubb4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39225,112,170 - 25,114,714 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl225,112,172 - 25,114,714 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38225,222,158 - 25,224,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl225,222,160 - 25,224,702 (-)Ensemblmm10GRCm38
MGSCv37225,077,678 - 25,080,222 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36225,044,171 - 25,046,650 (-)NCBIMGSCv36mm8
Celera224,949,941 - 24,952,486 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map217.08NCBI
Tubb4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555135,235,629 - 5,239,370 (+)Ensembl
ChiLan1.0NW_0049555135,237,050 - 5,239,370 (+)NCBIChiLan1.0ChiLan1.0
TUBB4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,155,911 - 2,159,194 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,158,244 - 2,160,933 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09108,300,868 - 108,303,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19137,269,849 - 137,271,758 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9137,268,942 - 137,271,758 (+)EnsemblpanPan2panpan1.1
TUBB4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,432,114 - 48,434,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,427,766 - 48,571,640 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha947,618,435 - 47,620,948 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0949,293,272 - 49,295,782 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,289,395 - 49,295,750 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,069,677 - 48,072,187 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,368,505 - 48,371,015 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,415,650 - 48,418,163 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tubb4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,623,429 - 202,625,856 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936669749,202 - 751,739 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936669749,203 - 751,622 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TUBB4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21314,135,349 - 314,137,803 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TUBB4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112945,643 - 948,087 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12945,459 - 948,065 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660584,357,929 - 4,360,605 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tubb4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624760712,987 - 717,951 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624760715,013 - 717,462 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tubb4b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1511,957,339 - 11,959,817 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tubb4b
9 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:82
Interacting mature miRNAs:85
Transcripts:ENSRNOT00000013863
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3136721849Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000013863   ⟹   ENSRNOP00000013863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl328,435,999 - 28,439,719 (-)Ensembl
mRatBN7.2 Ensembl38,037,799 - 8,040,296 (-)Ensembl
Rnor_6.0 Ensembl32,441,733 - 2,444,281 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000024947   ⟹   ENSRNOP00000024947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl328,435,148 - 28,438,457 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102939   ⟹   ENSRNOP00000078046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl328,436,149 - 28,438,457 (-)Ensembl
mRatBN7.2 Ensembl38,037,988 - 8,040,296 (-)Ensembl
RefSeq Acc Id: NM_199094   ⟹   NP_954525
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8328,435,999 - 28,438,455 (-)NCBI
mRatBN7.238,037,838 - 8,040,294 (-)NCBI
Rnor_6.032,441,589 - 2,444,348 (-)NCBI
Rnor_5.032,422,868 - 2,425,649 (-)NCBI
RGSC_v3.433,387,050 - 3,389,500 (-)RGD
Celera32,864,558 - 2,867,008 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_954525 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH60597 (Get FASTA)   NCBI Sequence Viewer  
  EDL93630 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024947
GenBank Protein Q6P9T8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_954525   ⟸   NM_199094
- UniProtKB: Q6P9T8 (UniProtKB/Swiss-Prot),   A6JT17 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013863   ⟸   ENSRNOT00000013863
Ensembl Acc Id: ENSRNOP00000078046   ⟸   ENSRNOT00000102939
Ensembl Acc Id: ENSRNOP00000024947   ⟸   ENSRNOT00000024947
Protein Domains
Tubulin/FtsZ 2-layer sandwich   Tubulin/FtsZ GTPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P9T8-F1-model_v2 AlphaFold Q6P9T8 1-445 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691861
Promoter ID:EPDNEW_R2386
Type:multiple initiation site
Name:Tubb4b_1
Description:tubulin, beta 4B class IVb
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.032,444,348 - 2,444,408EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735101 AgrOrtholog
BioCyc Gene G2FUF-50476 BioCyc
Ensembl Genes ENSRNOG00000010170 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000024947 ENTREZGENE
Gene3D-CATH 1.10.287.600 UniProtKB/Swiss-Prot
  3.30.1330.20 UniProtKB/Swiss-Prot
  3.40.50.1440 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6889737 IMAGE-MGC_LOAD
InterPro Beta-tubulin_BS UniProtKB/Swiss-Prot
  Beta_tubulin UniProtKB/Swiss-Prot
  Tub_FtsZ_C UniProtKB/Swiss-Prot
  Tubulin UniProtKB/Swiss-Prot
  Tubulin/FtsZ_2-layer-sand-dom UniProtKB/Swiss-Prot
  Tubulin/FtsZ_C_sf UniProtKB/Swiss-Prot
  Tubulin/FtsZ_GTPase_sf UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
  Tubulin_CS UniProtKB/Swiss-Prot
  Tubulin_FtsZ_GTPase UniProtKB/Swiss-Prot
KEGG Report rno:296554 UniProtKB/Swiss-Prot
MGC_CLONE MGC:73008 IMAGE-MGC_LOAD
NCBI Gene 296554 ENTREZGENE
PANTHER PTHR11588 UniProtKB/Swiss-Prot
Pfam Tubulin UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
PhenoGen Tubb4b PhenoGen
PRINTS BETATUBULIN UniProtKB/Swiss-Prot
  TUBULIN UniProtKB/Swiss-Prot
PROSITE TUBULIN UniProtKB/Swiss-Prot
  TUBULIN_B_AUTOREG UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010170 RatGTEx
SMART Tubulin UniProtKB/Swiss-Prot
  Tubulin_C UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52490 UniProtKB/Swiss-Prot
  SSF55307 UniProtKB/Swiss-Prot
UniProt A0A8I5Y8E3_RAT UniProtKB/TrEMBL
  A6JT17 ENTREZGENE, UniProtKB/TrEMBL
  G3V7C6_RAT UniProtKB/TrEMBL
  Q6P9T8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-10-19 Tubb4b  tubulin, beta 4B class IVb  Tubb2c  tubulin, beta 2C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-10-12 Tubb2c  tubulin, beta 2C  Tubb4b  tubulin, beta 4B class IVb  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-10-10 Tubb4b  tubulin, beta 4B class IVb  Tubb2c  tubulin, beta 2c  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tubb2c  tubulin, beta 2c  Tubb2  tubulin, beta, 2  Symbol and Name updated 1299863 APPROVED
2005-07-08 Tubb2  tubulin, beta, 2  MGC73008  Unknown (protein for MGC:73008)  Symbol and Name updated 1299863 APPROVED