Kif2a (kinesin family member 2A) - Rat Genome Database

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Gene: Kif2a (kinesin family member 2A) Rattus norvegicus
Analyze
Symbol: Kif2a
Name: kinesin family member 2A
RGD ID: 70974
Description: Enables protein kinase binding activity. Involved in anterograde axonal transport. Predicted to be located in microtubule cytoskeleton; nuclear lumen; and sperm principal piece. Predicted to be part of centriolar subdistal appendage and kinesin complex. Predicted to be active in GABA-ergic synapse; cytoplasm; and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 3. Orthologous to human KIF2A (kinesin family member 2A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Kif2; kinesin heavy chain family, member 2; kinesin heavy chain member 2; kinesin heavy chain member 2A; kinesin-2; kinesin-like protein KIF2A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8240,101,548 - 40,164,780 (-)NCBIGRCr8
mRatBN7.2238,367,998 - 38,431,237 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl238,367,998 - 38,431,508 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx245,491,535 - 45,554,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0243,550,214 - 43,613,432 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0238,397,498 - 38,460,714 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0238,145,507 - 38,208,765 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl238,147,601 - 38,208,719 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0257,240,240 - 57,302,984 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4238,079,564 - 38,143,398 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1238,002,008 - 38,013,924 (-)NCBI
Celera234,235,756 - 34,298,829 (-)NCBICelera
Cytogenetic Map2q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique. Debernardi S, etal., Genomics 1997 May 15;42(1):67-73.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B. Noda Y, etal., J Cell Biol. 1995 Apr;129(1):157-67. doi: 10.1083/jcb.129.1.157.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation. Watanabe T, etal., J Cell Biol. 2015 Aug 31;210(5):737-51. doi: 10.1083/jcb.201412075.
Additional References at PubMed
PMID:12477932   PMID:15843429   PMID:17728463   PMID:18411309   PMID:19946888   PMID:21399614   PMID:23213374   PMID:24339785   PMID:29476059   PMID:30053369   PMID:31041455   PMID:31514228  


Genomics

Comparative Map Data
Kif2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8240,101,548 - 40,164,780 (-)NCBIGRCr8
mRatBN7.2238,367,998 - 38,431,237 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl238,367,998 - 38,431,508 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx245,491,535 - 45,554,753 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0243,550,214 - 43,613,432 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0238,397,498 - 38,460,714 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0238,145,507 - 38,208,765 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl238,147,601 - 38,208,719 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0257,240,240 - 57,302,984 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4238,079,564 - 38,143,398 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1238,002,008 - 38,013,924 (-)NCBI
Celera234,235,756 - 34,298,829 (-)NCBICelera
Cytogenetic Map2q13NCBI
KIF2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38562,306,206 - 62,391,025 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl562,306,162 - 62,391,025 (+)EnsemblGRCh38hg38GRCh38
GRCh37561,602,033 - 61,686,852 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36561,637,746 - 61,717,967 (+)NCBINCBI36Build 36hg18NCBI36
Build 34561,678,712 - 61,717,967NCBI
Celera558,597,901 - 58,678,136 (+)NCBICelera
Cytogenetic Map5q12.1NCBI
HuRef558,558,087 - 58,639,465 (+)NCBIHuRef
CHM1_1561,601,610 - 61,682,674 (+)NCBICHM1_1
T2T-CHM13v2.0563,125,434 - 63,210,585 (+)NCBIT2T-CHM13v2.0
Kif2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913107,095,504 - 107,158,931 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13107,095,504 - 107,158,634 (-)EnsemblGRCm39 Ensembl
GRCm3813106,958,996 - 107,022,355 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13106,958,996 - 107,022,126 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713107,750,665 - 107,812,194 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613108,081,645 - 108,142,499 (-)NCBIMGSCv36mm8
Celera13111,296,434 - 111,357,980 (-)NCBICelera
Cytogenetic Map13D2.1NCBI
cM Map1358.06NCBI
Kif2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554466,244,547 - 6,279,089 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554466,244,547 - 6,279,080 (-)NCBIChiLan1.0ChiLan1.0
KIF2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2451,526,263 - 51,606,649 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1549,679,897 - 49,760,283 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0551,605,954 - 51,690,921 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1553,251,415 - 53,332,218 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl553,251,415 - 53,332,218 (-)Ensemblpanpan1.1panPan2
KIF2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1248,642,961 - 48,715,605 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl248,645,380 - 48,714,025 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha245,653,412 - 45,726,282 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0249,120,201 - 49,193,369 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl249,123,873 - 49,194,809 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1246,189,037 - 46,262,137 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0246,976,421 - 47,049,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0247,832,428 - 47,905,530 (+)NCBIUU_Cfam_GSD_1.0
Kif2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213197,386,873 - 197,421,209 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364806,324,216 - 6,357,741 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364806,324,214 - 6,357,696 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1641,016,674 - 41,102,545 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11641,016,680 - 41,101,122 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KIF2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1458,486,642 - 58,566,732 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl458,486,723 - 58,565,117 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660497,016,680 - 7,100,358 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248157,504,977 - 7,585,743 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248157,504,977 - 7,585,762 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kif2a
96 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:67
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000019189, ENSRNOT00000019225
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21159110056591100Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22238462767384627Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2141244106Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)22997159351729300Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
738012Anxrr3Anxiety related response QTL 33.8exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)2902351954023519Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22699957143154682Rat
731179Mamtr3Mammary tumor resistance QTL 30.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)23237377043665178Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2788777242804738Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1643006Pain1Pain QTL 13.630.005mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)22699957148268661Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)21185206249003364Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)228484589169504100Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)228484589169504100Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat

Markers in Region
RH132232  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2238,368,260 - 38,368,452 (+)MAPPERmRatBN7.2
Rnor_6.0238,145,770 - 38,145,961NCBIRnor6.0
Rnor_5.0257,240,503 - 57,240,694UniSTSRnor5.0
RGSC_v3.4238,079,827 - 38,080,018UniSTSRGSC3.4
Celera234,236,019 - 34,236,210UniSTS
RH 3.4 Map2177.2UniSTS
Cytogenetic Map2q14UniSTS
RH139596  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2238,367,968 - 38,368,164 (+)MAPPERmRatBN7.2
Rnor_6.0238,145,478 - 38,145,673NCBIRnor6.0
Rnor_5.0257,240,211 - 57,240,406UniSTSRnor5.0
RGSC_v3.4238,079,535 - 38,079,730UniSTSRGSC3.4
Celera234,235,727 - 34,235,922UniSTS
RH 3.4 Map2177.4UniSTS
Cytogenetic Map2q14UniSTS
RH140326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2238,369,417 - 38,369,665 (+)MAPPERmRatBN7.2
Rnor_6.0238,146,927 - 38,147,174NCBIRnor6.0
Rnor_5.0257,241,660 - 57,241,907UniSTSRnor5.0
RGSC_v3.4238,080,984 - 38,081,231UniSTSRGSC3.4
Celera234,237,176 - 34,237,423UniSTS
RH 3.4 Map2179.4UniSTS
Cytogenetic Map2q14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000019189   ⟹   ENSRNOP00000019189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl238,367,998 - 38,431,508 (-)Ensembl
Rnor_6.0 Ensembl238,147,601 - 38,208,719 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093988   ⟹   ENSRNOP00000095843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl238,367,998 - 38,402,893 (-)Ensembl
RefSeq Acc Id: NM_053376   ⟹   NP_445828
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8240,101,548 - 40,164,780 (-)NCBI
mRatBN7.2238,367,998 - 38,431,237 (-)NCBI
Rnor_6.0238,145,507 - 38,208,765 (-)NCBI
Rnor_5.0257,240,240 - 57,302,984 (-)NCBI
Celera234,235,756 - 34,298,829 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_445828 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD39241 (Get FASTA)   NCBI Sequence Viewer  
  AAH91304 (Get FASTA)   NCBI Sequence Viewer  
  EDM10287 (Get FASTA)   NCBI Sequence Viewer  
  EDM10288 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019189.6
  ENSRNOP00000095843.1
GenBank Protein Q9WV63 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445828   ⟸   NM_053376
- UniProtKB: Q9WV63 (UniProtKB/Swiss-Prot),   Q5BJW1 (UniProtKB/Swiss-Prot),   A6I5H9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019189   ⟸   ENSRNOT00000019189
Ensembl Acc Id: ENSRNOP00000095843   ⟸   ENSRNOT00000093988
Protein Domains
Kinesin motor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WV63-F1-model_v2 AlphaFold Q9WV63 1-705 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70974 AgrOrtholog
BioCyc Gene G2FUF-54524 BioCyc
Ensembl Genes ENSRNOG00000014000 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019189.7 UniProtKB/TrEMBL
  ENSRNOT00000093988.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7310909 IMAGE-MGC_LOAD
InterPro KIF2A-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin-like_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:84391 UniProtKB/TrEMBL
MGC_CLONE MGC:109252 IMAGE-MGC_LOAD
NCBI Gene 84391 ENTREZGENE
PANTHER KINESIN-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN-RELATED PROTEIN 6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam KIF2A-like_1st UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kif2a PhenoGen
PRINTS KINESINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014000 RatGTEx
SMART KISc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AU93_RAT UniProtKB/TrEMBL
  A6I5H9 ENTREZGENE, UniProtKB/TrEMBL
  F1M8L1_RAT UniProtKB/TrEMBL
  KIF2A_RAT UniProtKB/Swiss-Prot
  Q5BJW1 ENTREZGENE
  Q9WV63 ENTREZGENE
UniProt Secondary Q5BJW1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Kif2a  kinesin family member 2A  Kif2a  kinesin heavy chain member 2A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-29 Kif2a  kinesin heavy chain member 2A  Kif2a  kinesin family member 2A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Kif2a  kinesin family member 2A  Kif2  kinesin heavy chain family, member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Kif2  kinesin heavy chain family, member 2    kinesin heavy chain member 2  Name updated 1299863 APPROVED
2002-07-09 Kif2  kinesin heavy chain member 2      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function essential for the bipolarity of spindle assembly in cultured non-neuronal human, frog and hamster cells during mitosis 1358126
gene_function in mouse brain, involved in suppression of collateral branch extension during neuronal development, possibly by depolymerizing microtubules at the growth cone edge 1358127