Csap1 (common salivary protein 1) - Rat Genome Database

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Gene: Csap1 (common salivary protein 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Csap1
Name: common salivary protein 1
RGD ID: 708577
Description: Predicted to enable carbohydrate binding activity. Located in extracellular space. Orthologous to human ZG16B (zymogen granule protein 16B); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CSP1
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,414,952 - 13,420,913 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1013,416,336 - 13,420,908 (+)EnsemblGRCr8
mRatBN7.21012,910,368 - 12,916,336 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,914,455 - 12,916,334 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1017,659,247 - 17,661,218 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,148,033 - 17,150,004 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,647,212 - 12,649,183 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,230,181 - 13,230,577 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,230,158 - 13,230,575 (+)Ensemblrn6Rnor6.0
Rnor_5.01013,049,128 - 13,049,524 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1012,607,789 - 12,609,733 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Characterization of common salivary protein 1, a product of rat submandibular, sublingual, and parotid glands. Girard LR, etal., J Biol Chem 1993 Dec 15;268(35):26592-601.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548  


Genomics

Variants

.
Variants in Csap1
21 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:41
Count of miRNA genes:36
Interacting mature miRNAs:39
Transcripts:ENSRNOT00000075648
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat

Markers in Region
BI279212  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21012,915,953 - 12,916,129 (+)MAPPERmRatBN7.2
Rnor_6.01013,230,195 - 13,230,370NCBIRnor6.0
Rnor_5.01013,049,142 - 13,049,317UniSTSRnor5.0
Celera1012,609,351 - 12,609,526UniSTS
RH 3.4 Map10145.85UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
4 2 12 53 18 23 2 3 2 1 46 20 56 18 52 21

Sequence


Ensembl Acc Id: ENSRNOT00000075648   ⟹   ENSRNOP00000065441
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1013,416,336 - 13,420,908 (+)Ensembl
mRatBN7.2 Ensembl1012,914,455 - 12,916,334 (+)Ensembl
Rnor_6.0 Ensembl1013,230,158 - 13,230,575 (+)Ensembl
RefSeq Acc Id: NM_133622   ⟹   NP_598306
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,418,942 - 13,420,913 (+)NCBI
mRatBN7.21012,914,365 - 12,916,336 (+)NCBI
Rnor_6.01013,230,181 - 13,230,577 (+)NCBI
Rnor_5.01013,049,128 - 13,049,524 (+)NCBI
Celera1012,607,789 - 12,609,733 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085154   ⟹   XP_038941082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,414,952 - 13,420,913 (+)NCBI
mRatBN7.21012,910,368 - 12,916,336 (+)NCBI
Protein Sequences
Protein RefSeqs NP_598306 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941082 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA16140 (Get FASTA)   NCBI Sequence Viewer  
  EDM03792 (Get FASTA)   NCBI Sequence Viewer  
  EDM03793 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065441
  ENSRNOP00000065441.2
RefSeq Acc Id: NP_598306   ⟸   NM_133622
- Peptide Label: precursor
- UniProtKB: Q63015 (UniProtKB/TrEMBL),   M0R7K9 (UniProtKB/TrEMBL),   A6HCN7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065441   ⟸   ENSRNOT00000075648
RefSeq Acc Id: XP_038941082   ⟸   XM_039085154
- Peptide Label: isoform X1
- UniProtKB: M0R7K9 (UniProtKB/TrEMBL),   A6HCN7 (UniProtKB/TrEMBL),   Q63015 (UniProtKB/TrEMBL)
Protein Domains
Jacalin-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R7K9-F1-model_v2 AlphaFold M0R7K9 1-114 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708577 AgrOrtholog
BioCyc Gene G2FUF-25892 BioCyc
Ensembl Genes ENSRNOG00000049151 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075648 ENTREZGENE
  ENSRNOT00000075648.3 UniProtKB/TrEMBL
Gene3D-CATH 2.100.10.30 UniProtKB/TrEMBL
InterPro Jacalin-like_lectin_dom_sf UniProtKB/TrEMBL
  Mannose-bd_lectin UniProtKB/TrEMBL
  PolyBind_ProtTraffic UniProtKB/TrEMBL
KEGG Report rno:171161 UniProtKB/TrEMBL
NCBI Gene 171161 ENTREZGENE
PANTHER OS11G0524900 PROTEIN UniProtKB/TrEMBL
  ZYMOGEN GRANULE PROTEIN 16 HOMOLOG B UniProtKB/TrEMBL
PhenoGen Csap1 PhenoGen
RatGTEx ENSRNOG00000049151 RatGTEx
SMART Jacalin UniProtKB/TrEMBL
Superfamily-SCOP Mannose-bd_lectin UniProtKB/TrEMBL
UniProt A6HCN7 ENTREZGENE, UniProtKB/TrEMBL
  M0R7K9 ENTREZGENE, UniProtKB/TrEMBL
  Q63015 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-09-12 Csap1  common salivary protein 1  LOC171161  common salivary protein 1  Symbol changed 629549 APPROVED
2006-02-09 LOC171161  common salivary protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL