Stxbp5 (syntaxin binding protein 5) - Rat Genome Database

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Gene: Stxbp5 (syntaxin binding protein 5) Rattus norvegicus
Analyze
Symbol: Stxbp5
Name: syntaxin binding protein 5
RGD ID: 708517
Description: Enables syntaxin-1 binding activity. Involved in synaptic vesicle cycle. Is active in several cellular components, including Schaffer collateral - CA1 synapse; presynaptic cytosol; and synaptic vesicle. Is extrinsic component of presynaptic membrane. Orthologous to human STXBP5 (syntaxin binding protein 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lethal(2) giant larvae protein homolog 3; syntaxin binding protein 5 (tomosyn); syntaxin-binding protein 5; tomosyn; tomosyn-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr816,002,738 - 6,155,528 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl16,002,738 - 6,155,528 (-)EnsemblGRCr8
mRatBN7.214,182,489 - 4,335,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13,859,705 - 4,009,270 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.019,860,141 - 10,009,704 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014,141,857 - 4,291,422 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013,858,917 - 4,011,684 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13,858,909 - 4,011,511 (-)Ensemblrn6Rnor6.0
Rnor_5.015,532,156 - 5,682,250 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414,428,182 - 4,579,373 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera12,725,757 - 2,875,514 (-)NCBICelera
RGSC_v3.114,428,181 - 4,579,373 (-)NCBI
Cytogenetic Map1p13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter. Baba T, etal., J Cell Biol. 2005 Sep 26;170(7):1113-25. doi: 10.1083/jcb.200504055.
2. Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn. Cazares VA, etal., J Neurosci. 2016 Nov 2;36(44):11208-11222. doi: 10.1523/JNEUROSCI.1297-16.2016.
3. Tomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis. Cheviet S, etal., J Cell Sci. 2006 Jul 15;119(Pt 14):2912-20. Epub 2006 Jun 20.
4. Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process. Fujita Y, etal., Neuron 1998 May;20(5):905-15.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Molecular anatomy of a trafficking organelle. Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46.
9. Three splicing variants of tomosyn and identification of their syntaxin-binding region. Yokoyama S, etal., Biochem Biophys Res Commun 1999 Mar 5;256(1):218-22.
Additional References at PubMed
PMID:12782620   PMID:12832401   PMID:14983051   PMID:15240567   PMID:15316007   PMID:16033762   PMID:16505218   PMID:18936251   PMID:19258327   PMID:20633536   PMID:20978127   PMID:21330375  
PMID:21810271   PMID:23519441   PMID:24782308   PMID:25063806   PMID:28746398   PMID:29269412  


Genomics

Comparative Map Data
Stxbp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr816,002,738 - 6,155,528 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl16,002,738 - 6,155,528 (-)EnsemblGRCr8
mRatBN7.214,182,489 - 4,335,290 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx13,859,705 - 4,009,270 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.019,860,141 - 10,009,704 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014,141,857 - 4,291,422 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.013,858,917 - 4,011,684 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13,858,909 - 4,011,511 (-)Ensemblrn6Rnor6.0
Rnor_5.015,532,156 - 5,682,250 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.414,428,182 - 4,579,373 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera12,725,757 - 2,875,514 (-)NCBICelera
RGSC_v3.114,428,181 - 4,579,373 (-)NCBI
Cytogenetic Map1p13NCBI
STXBP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386147,204,417 - 147,390,473 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6147,203,710 - 147,391,010 (+)Ensemblhg38GRCh38
GRCh376147,525,553 - 147,711,609 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366147,566,565 - 147,748,588 (+)NCBIBuild 36Build 36hg18NCBI36
Build 346147,566,567 - 147,748,584NCBI
Celera6148,265,949 - 148,449,151 (+)NCBICelera
Cytogenetic Map6q24.3NCBI
HuRef6145,089,042 - 145,275,226 (+)NCBIHuRef
CHM1_16147,788,922 - 147,975,011 (+)NCBICHM1_1
T2T-CHM13v2.06148,397,706 - 148,583,768 (+)NCBIT2T-CHM13v2.0
Stxbp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39109,631,285 - 9,776,987 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl109,631,291 - 9,776,823 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38109,755,547 - 9,901,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl109,755,547 - 9,901,079 (-)Ensemblmm10GRCm38
MGSCv37109,475,345 - 9,620,838 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36109,445,737 - 9,590,873 (-)NCBIMGSCv36mm8
Celera109,659,963 - 9,805,506 (-)NCBICelera
Cytogenetic Map10A1NCBI
cM Map103.21NCBI
Stxbp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543913,580,113 - 13,743,430 (-)Ensembl
ChiLan1.0NW_00495543913,580,106 - 13,743,430 (-)NCBIChiLan1.0ChiLan1.0
STXBP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25167,213,043 - 167,398,975 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16165,106,847 - 165,292,795 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06145,006,696 - 145,192,467 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16149,719,064 - 149,905,007 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6149,719,064 - 149,902,662 (+)EnsemblpanPan2panpan1.1
STXBP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1138,271,238 - 38,439,088 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl138,271,154 - 38,434,042 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha139,170,639 - 39,338,349 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0138,443,072 - 38,612,992 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl138,443,201 - 38,605,356 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1138,320,755 - 38,488,319 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0138,190,698 - 38,358,426 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0138,529,557 - 38,697,531 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Stxbp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946133,351,292 - 133,522,798 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936489612,124 - 768,722 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936489449,029 - 771,870 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STXBP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl118,345,363 - 18,513,252 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1118,343,826 - 18,512,750 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2120,543,226 - 20,705,846 (-)NCBISscrofa10.2Sscrofa10.2susScr3
STXBP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11324,365,022 - 24,559,249 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1324,367,627 - 24,559,269 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040200,313,238 - 200,504,306 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stxbp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478510,692,257 - 10,874,285 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478510,692,573 - 10,874,358 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Stxbp5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12227,168,368 - 227,311,888 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Stxbp5
1177 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:217
Count of miRNA genes:79
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000040559, ENSRNOT00000044778, ENSRNOT00000049699
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
RH144675  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.214,185,283 - 4,185,446 (+)MAPPERmRatBN7.2
Rnor_6.013,861,708 - 3,861,870NCBIRnor6.0
Rnor_5.015,534,947 - 5,535,109UniSTSRnor5.0
RGSC_v3.414,427,937 - 4,428,099UniSTSRGSC3.4
Celera12,725,512 - 2,725,674UniSTS
RH 3.4 Map177.6UniSTS
Cytogenetic Map1p13UniSTS
BF390393  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.214,279,606 - 4,279,826 (+)MAPPERmRatBN7.2
Rnor_6.013,956,028 - 3,956,247NCBIRnor6.0
Rnor_5.015,627,828 - 5,628,047UniSTSRnor5.0
RGSC_v3.414,522,518 - 4,522,736UniSTSRGSC3.4
Celera12,819,704 - 2,819,923UniSTS
RH 3.4 Map177.2UniSTS
Cytogenetic Map1p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_030843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_178345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_178346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF118889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF118890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U92072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000040559   ⟹   ENSRNOP00000044738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,002,738 - 6,155,528 (-)Ensembl
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)Ensembl
Rnor_6.0 Ensembl13,861,953 - 4,011,511 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000044778   ⟹   ENSRNOP00000039502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,007,712 - 6,155,528 (-)Ensembl
mRatBN7.2 Ensembl14,187,467 - 4,335,101 (-)Ensembl
Rnor_6.0 Ensembl13,862,091 - 4,011,161 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000049699   ⟹   ENSRNOP00000049322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,002,738 - 6,155,528 (-)Ensembl
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)Ensembl
Rnor_6.0 Ensembl13,858,909 - 4,011,353 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094037   ⟹   ENSRNOP00000087436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,002,738 - 6,155,528 (-)Ensembl
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096129   ⟹   ENSRNOP00000095824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,002,738 - 6,155,528 (-)Ensembl
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100093   ⟹   ENSRNOP00000092275
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,002,738 - 6,155,528 (-)Ensembl
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115103   ⟹   ENSRNOP00000092947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,002,738 - 6,155,528 (-)Ensembl
mRatBN7.2 Ensembl14,185,529 - 4,335,101 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133785   ⟹   ENSRNOP00000099537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl16,002,738 - 6,155,188 (-)Ensembl
RefSeq Acc Id: NM_030843   ⟹   NP_110470
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,002,738 - 6,155,528 (-)NCBI
mRatBN7.214,182,493 - 4,335,290 (-)NCBI
Rnor_6.013,861,953 - 4,011,511 (-)NCBI
Rnor_5.015,532,156 - 5,682,250 (-)NCBI
RGSC_v3.414,428,182 - 4,579,373 (-)RGD
Celera12,725,757 - 2,875,514 (-)RGD
Sequence:
RefSeq Acc Id: NM_178345   ⟹   NP_848035
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,002,738 - 6,155,528 (-)NCBI
mRatBN7.214,182,493 - 4,335,290 (-)NCBI
Rnor_6.013,862,091 - 4,011,161 (-)NCBI
Rnor_5.015,532,156 - 5,682,250 (-)NCBI
RGSC_v3.414,428,182 - 4,579,373 (-)RGD
Celera12,725,895 - 2,875,164 (-)NCBI
Sequence:
RefSeq Acc Id: NM_178346   ⟹   NP_848036
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,002,738 - 6,155,528 (-)NCBI
mRatBN7.214,182,493 - 4,335,290 (-)NCBI
Rnor_6.013,862,091 - 4,011,161 (-)NCBI
Rnor_5.015,532,156 - 5,682,250 (-)NCBI
RGSC_v3.414,428,182 - 4,579,373 (-)RGD
Celera12,725,895 - 2,875,164 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091853   ⟹   XP_038947781
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,002,738 - 6,155,528 (-)NCBI
mRatBN7.214,182,489 - 4,335,267 (-)NCBI
RefSeq Acc Id: XM_039091859   ⟹   XP_038947787
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,023,032 - 6,155,528 (-)NCBI
mRatBN7.214,202,786 - 4,335,271 (-)NCBI
RefSeq Acc Id: XM_039091862   ⟹   XP_038947790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,025,299 - 6,155,528 (-)NCBI
mRatBN7.214,206,799 - 4,335,271 (-)NCBI
RefSeq Acc Id: XM_039091865   ⟹   XP_038947793
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,025,299 - 6,155,528 (-)NCBI
mRatBN7.214,207,771 - 4,335,271 (-)NCBI
RefSeq Acc Id: XM_039091874   ⟹   XP_038947802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,025,299 - 6,155,528 (-)NCBI
mRatBN7.214,207,771 - 4,335,270 (-)NCBI
RefSeq Acc Id: XM_039091879   ⟹   XP_038947807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,023,032 - 6,155,528 (-)NCBI
mRatBN7.214,202,787 - 4,335,270 (-)NCBI
RefSeq Acc Id: XM_039091888   ⟹   XP_038947816
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,030,452 - 6,155,528 (-)NCBI
mRatBN7.214,210,040 - 4,335,270 (-)NCBI
RefSeq Acc Id: XM_063274968   ⟹   XP_063131038
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,002,738 - 6,155,504 (-)NCBI
RefSeq Acc Id: XM_063274970   ⟹   XP_063131040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,014,622 - 6,155,528 (-)NCBI
RefSeq Acc Id: XM_063274990   ⟹   XP_063131060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,002,738 - 6,155,528 (-)NCBI
RefSeq Acc Id: XM_063275001   ⟹   XP_063131071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,002,738 - 6,155,528 (-)NCBI
RefSeq Acc Id: XR_005492935
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,015,963 - 6,155,528 (-)NCBI
mRatBN7.214,195,715 - 4,335,271 (-)NCBI
RefSeq Acc Id: XR_005492948
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr816,015,963 - 6,155,528 (-)NCBI
mRatBN7.214,195,715 - 4,335,270 (-)NCBI
RefSeq Acc Id: NP_110470   ⟸   NM_030843
- Peptide Label: isoform m
- UniProtKB: A6JP29 (UniProtKB/TrEMBL),   A0A8I6GF49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_848036   ⟸   NM_178346
- Peptide Label: isoform s
- UniProtKB: A6JP28 (UniProtKB/TrEMBL),   A0A8I6GF49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_848035   ⟸   NM_178345
- Peptide Label: isoform b
- UniProtKB: Q9WU71 (UniProtKB/Swiss-Prot),   Q9Z152 (UniProtKB/Swiss-Prot),   Q9WU70 (UniProtKB/Swiss-Prot),   A6JP31 (UniProtKB/TrEMBL),   A0A8I6APW1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039502   ⟸   ENSRNOT00000044778
Ensembl Acc Id: ENSRNOP00000049322   ⟸   ENSRNOT00000049699
Ensembl Acc Id: ENSRNOP00000044738   ⟸   ENSRNOT00000040559
RefSeq Acc Id: XP_038947781   ⟸   XM_039091853
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QLQ5 (UniProtKB/TrEMBL),   A6JP30 (UniProtKB/TrEMBL),   A0A8L2QJB5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947787   ⟸   XM_039091859
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038947807   ⟸   XM_039091879
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038947790   ⟸   XM_039091862
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038947793   ⟸   XM_039091865
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038947802   ⟸   XM_039091874
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038947816   ⟸   XM_039091888
- Peptide Label: isoform X9
Ensembl Acc Id: ENSRNOP00000087436   ⟸   ENSRNOT00000094037
Ensembl Acc Id: ENSRNOP00000092947   ⟸   ENSRNOT00000115103
Ensembl Acc Id: ENSRNOP00000092275   ⟸   ENSRNOT00000100093
Ensembl Acc Id: ENSRNOP00000095824   ⟸   ENSRNOT00000096129
RefSeq Acc Id: XP_063131071   ⟸   XM_063275001
- Peptide Label: isoform X11
- UniProtKB: A0A8I6ADC8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131060   ⟸   XM_063274990
- Peptide Label: isoform X10
- UniProtKB: A0A8I6ADC8 (UniProtKB/TrEMBL),   A0A8I6AIJ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131038   ⟸   XM_063274968
- Peptide Label: isoform X2
- UniProtKB: A0A8I6APW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063131040   ⟸   XM_063274970
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000099537   ⟸   ENSRNOT00000133785
Protein Domains
v-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WU70-F1-model_v2 AlphaFold Q9WU70 1-1152 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689488
Promoter ID:EPDNEW_R11
Type:single initiation site
Name:Stxbp5_1
Description:syntaxin binding protein 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014,011,415 - 4,011,475EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708517 AgrOrtholog
BioCyc Gene G2FUF-62422 BioCyc
Ensembl Genes ENSRNOG00000013351 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000040559 ENTREZGENE
  ENSRNOT00000049699 ENTREZGENE
  ENSRNOT00000049699.7 UniProtKB/Swiss-Prot
  ENSRNOT00000115103 ENTREZGENE
  ENSRNOT00000133785 ENTREZGENE
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
  2.130.10.10 UniProtKB/Swiss-Prot
InterPro Lethal2_giant UniProtKB/Swiss-Prot
  Lgl_C_dom UniProtKB/Swiss-Prot
  LLGL2 UniProtKB/Swiss-Prot
  V_SNARE_CC UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:81022 UniProtKB/Swiss-Prot
NCBI Gene 81022 ENTREZGENE
PANTHER LETHAL 2 GIANT LARVAE PROTEIN UniProtKB/Swiss-Prot
  SYNTAXIN-BINDING PROTEIN 5 UniProtKB/Swiss-Prot
Pfam Lgl_C UniProtKB/Swiss-Prot
  LLGL UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Stxbp5 PhenoGen
PRINTS LETHAL2GIANT UniProtKB/Swiss-Prot
PROSITE V_SNARE UniProtKB/Swiss-Prot
  WD_REPEATS_1 UniProtKB/Swiss-Prot
  WD_REPEATS_2 UniProtKB/Swiss-Prot
  WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013351 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot
  SSF50978 UniProtKB/Swiss-Prot
UniProt A0A8I6ADC8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIJ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APW1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GF49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QJB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QLQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LDK6_RAT UniProtKB/TrEMBL
  A6JP28 ENTREZGENE, UniProtKB/TrEMBL
  A6JP29 ENTREZGENE, UniProtKB/TrEMBL
  A6JP30 ENTREZGENE, UniProtKB/TrEMBL
  A6JP31 ENTREZGENE, UniProtKB/TrEMBL
  Q9WU70 ENTREZGENE
  Q9WU71 ENTREZGENE
  Q9Z152 ENTREZGENE
  STXB5_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q9WU71 UniProtKB/Swiss-Prot
  Q9Z152 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Stxbp5  syntaxin binding protein 5  Stxbp5  syntaxin binding protein 5 (tomosyn)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Stxbp5  syntaxin binding protein 5 (tomosyn)      Symbol and Name status set to approved 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference