Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of TMEM33 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | Tmem33 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TMEM33 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of TMEM33 mRNA | CTD | PMID:35192832 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmem33 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM33 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TMEM33 mRNA] | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM33 mRNA | CTD | PMID:15034205 and PMID:19465110 | 2,4,6-tribromophenol | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of TMEM33 protein | CTD | PMID:31675489 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Tmem33 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TMEM33 mRNA | CTD | PMID:26251327 | 5-fluorouracil | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Fluorouracil results in decreased expression of TMEM33 mRNA | CTD | PMID:16510598 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of TMEM33 mRNA | CTD | PMID:31881176 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of TMEM33 mRNA | CTD | PMID:16483693 | antirheumatic drug | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TMEM33 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of TMEM33 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | increases methylation | ISO | TMEM33 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TMEM33 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TMEM33 mRNA | CTD | PMID:15034205 more ... | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TMEM33 promoter | CTD | PMID:23359474 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TMEM33 promoter | CTD | PMID:23359474 | bisphenol A | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TMEM33 protein | CTD | PMID:31675489 more ... | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TMEM33 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Tmem33 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TMEM33 mRNA | CTD | PMID:26063408 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of TMEM33 mRNA | CTD | PMID:24136188 | cadmium atom | multiple interactions | ISO | TMEM33 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TMEM33 mRNA | CTD | PMID:35301059 | cadmium dichloride | affects expression | ISO | Tmem33 (Mus musculus) | 6480464 | Cadmium Chloride affects the expression of TMEM33 mRNA | CTD | PMID:16842966 | cadmium dichloride | multiple interactions | ISO | TMEM33 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TMEM33 mRNA | CTD | PMID:35301059 | carbon nanotube | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | TMEM33 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TMEM33 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TMEM33 mRNA | CTD | PMID:37019170 | choline | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TMEM33 mRNA | CTD | PMID:20938992 | cisplatin | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of TMEM33 mRNA | CTD | PMID:27594783 | clofibrate | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Clofibrate results in increased expression of TMEM33 mRNA | CTD | PMID:23811191 | copper atom | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of TMEM33 mRNA | CTD | PMID:15467011 | copper(0) | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of TMEM33 mRNA | CTD | PMID:15467011 | copper(II) sulfate | increases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TMEM33 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TMEM33 mRNA | CTD | PMID:25562108 and PMID:27989131 | decabromodiphenyl ether | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of TMEM33 protein | CTD | PMID:31675489 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TMEM33 promoter | CTD | PMID:23359474 | ethanol | affects splicing | ISO | Tmem33 (Mus musculus) | 6480464 | Ethanol affects the splicing of TMEM33 mRNA | CTD | PMID:30319688 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of TMEM33 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TMEM33 mRNA | CTD | PMID:20938992 | geldanamycin | increases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of TMEM33 mRNA | CTD | PMID:26705709 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TMEM33 mRNA | CTD | PMID:22061828 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TMEM33 mRNA | CTD | PMID:33387578 | hypochlorous acid | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Hypochlorous Acid results in increased expression of TMEM33 mRNA | CTD | PMID:19376150 | isotretinoin | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of TMEM33 mRNA | CTD | PMID:20436886 | ivermectin | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TMEM33 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TMEM33 mRNA | CTD | PMID:20938992 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of TMEM33 mRNA | CTD | PMID:24136188 | methidathion | decreases expression | ISO | Tmem33 (Mus musculus) | 6480464 | methidathion results in decreased expression of TMEM33 mRNA | CTD | PMID:34813904 | methylmercury chloride | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of TMEM33 mRNA | CTD | PMID:28001369 | methylmercury chloride | increases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TMEM33 mRNA | CTD | PMID:28001369 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of TMEM33 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of TMEM33 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | Tmem33 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in increased expression of TMEM33 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | ISO | Tmem33 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TMEM33 mRNA | CTD | PMID:17562736 | pentachlorophenol | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of TMEM33 mRNA | CTD | PMID:23892564 | pirinixic acid | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TMEM33 mRNA | CTD | PMID:18301758 and PMID:23811191 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of TMEM33 mRNA | CTD | PMID:22698814 | propiconazole | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | propiconazole results in increased expression of TMEM33 mRNA | CTD | PMID:21278054 | resveratrol | increases expression | ISO | Tmem33 (Mus musculus) | 6480464 | resveratrol results in increased expression of TMEM33 protein | CTD | PMID:25505154 | resveratrol | multiple interactions | ISO | TMEM33 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TMEM33 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | TMEM33 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of TMEM33 protein | CTD | PMID:37664457 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of TMEM33 mRNA | CTD | PMID:19281266 | thimerosal | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of TMEM33 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TMEM33 mRNA | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TMEM33 mRNA | CTD | PMID:23179753 | vorinostat | decreases expression | ISO | TMEM33 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of TMEM33 mRNA | CTD | PMID:27188386 | |