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Gene: Cyp4f4 (cytochrome P450, family 4, subfamily f, polypeptide 4) Rattus norvegicus

Analyze

No known orthologs.

Symbol:

Cyp4f4

Name:

cytochrome P450, family 4, subfamily f, polypeptide 4

RGD ID:

708363

Description:

Enables arachidonate monooxygenase activity; heme binding activity; and leukotriene-B4 20-monooxygenase activity. Involved in icosanoid catabolic process; omega-hydroxylase P450 pathway; and response to 3-methylcholanthrene. Predicted to be located in endoplasmic reticulum membrane. Biomarker of hypertrophic cardiomyopathy. Orthologous to human CYP4F11 (cytochrome P450 family 4 subfamily F member 11); PARTICIPATES IN arachidonic acid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 1-benzylpiperazine; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CYPIVF4; cytochrome P450 4F4; leukotriene-B4 20-monooxygenase

RGD Orthologs

Alliance Orthologs

More Info

homologs ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	12,367,711 - 12,384,010 (+)	NCBI		GRCr8
mRatBN7.2	7	11,717,208 - 11,733,507 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	11,717,208 - 11,733,506 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	14,527,006 - 14,543,308 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	16,404,445 - 16,420,747 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	14,284,640 - 14,300,959 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	14,891,062 - 14,907,250 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	14,891,001 - 14,907,305 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	15,045,084 - 15,061,272 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	13,293,080 - 13,309,416 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	13,293,079 - 13,309,415 (+)	NCBI
Celera	7	9,816,959 - 9,833,227 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hypertrophic cardiomyopathy (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1-benzylpiperazine (EXP)

17alpha-ethynylestradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3-methylcholanthrene (EXP)

acetamide (EXP)

allethrin (EXP)

amiodarone (EXP)

amitriptyline (EXP)

ammonium chloride (EXP)

barium sulfate (EXP)

benzo[a]pyrene (EXP)

beta-naphthoflavone (EXP)

bisphenol A (EXP)

buspirone (EXP)

cadmium dichloride (EXP)

clofibric acid (EXP)

clomipramine (EXP)

cobalt dichloride (EXP)

copper atom (EXP)

copper(0) (EXP)

cyhalothrin (EXP)

cypermethrin (EXP)

dichlorine (EXP)

doxorubicin (EXP)

endosulfan (EXP)

fenvalerate (EXP)

flutamide (EXP)

furan (EXP)

genistein (EXP)

glafenine (EXP)

imipramine (EXP)

ketoconazole (EXP)

kojic acid (EXP)

lead nitrate (EXP)

lipopolysaccharide (EXP)

manganese(II) chloride (EXP)

methamphetamine (EXP)

methoxychlor (EXP)

N-methyl-4-phenylpyridinium (EXP)

N-nitrosodiethylamine (EXP)

ozone (EXP)

pirinixic acid (EXP)

pregnenolone 16alpha-carbonitrile (EXP)

pyrethrins (EXP)

sodium dichromate (EXP)

Soman (EXP)

sunitinib (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichloroethene (EXP)

zinc atom (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

arachidonate metabolic process (IBA)

leukotriene B4 catabolic process (IBA,IDA)

omega-hydroxylase P450 pathway (IDA)

prostaglandin catabolic process (IDA)

response to 3-methylcholanthrene (IEP)

Cellular Component

endoplasmic reticulum membrane (IEA)

membrane (IEA)

Molecular Function

arachidonate monooxygenase activity (IBA,IDA)

arachidonate omega-hydroxylase activity (IEA)

heme binding (IDA,IEA)

iron ion binding (IEA)

leukotriene-B4 20-monooxygenase activity (IBA,IDA)

monooxygenase activity (IEA)

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

arachidonic acid metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats.	Aboutabl ME, etal., Br J Pharmacol. 2009 Dec;158(7):1808-19. doi: 10.1111/j.1476-5381.2009.00461.x.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	cDNA cloning of three new forms of rat brain cytochrome P450 belonging to the CYP4F subfamily.	Kawashima H and Strobel HW, Biochem Biophys Res Commun 1995 Dec 26;217(3):1137-44.
4.	Protein expression, characterization, and regulation of CYP4F4 and CYP4F5 cloned from rat brain.	Kawashima H, etal., Arch Biochem Biophys. 1997 Nov 1;347(1):148-54. doi: 10.1006/abbi.1997.0342.
5.	Covalent attachment of the heme prosthetic group in the CYP4F cytochrome P450 family.	LeBrun LA, etal., Biochemistry. 2002 May 7;41(18):5931-7.
6.	Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway.	Maayah ZH, etal., Arch Toxicol. 2014 Mar;88(3):725-38. doi: 10.1007/s00204-013-1159-5. Epub 2013 Nov 19.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes.	Xu F, etal., J Pharmacol Exp Ther. 2004 Mar;308(3):887-95. Epub 2003 Nov 21.

Additional References at PubMed

PMID:16182239

Genomics

Variants

Variants in Cyp4f4
69 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	33
Count of miRNA genes:	33
Interacting mature miRNAs:	33
Transcripts:	ENSRNOT00000041034
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	44782185	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	664270	26029351	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	5329019	50329019	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	9866467	60460686	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1	44822433	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
10755438	Coatc9	Coat color QTL 9		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	3529280	48529280	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	31962314	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	9462246	58265113	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	7573985	52573985	Rat
2317047	Wbc4	White blood cell count QTL 4		0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	7	1	35342956	Rat
10755440	Coatc10	Coat color QTL 10		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	7496499	52496499	Rat
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	27829089	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34000259	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	31962314	Rat

Markers in Region

D7Uwm5

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	11,716,588 - 11,716,821 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	14,890,443 - 14,890,675	NCBI	Rnor6.0
Rnor_5.0	7	15,044,465 - 15,044,697	UniSTS	Rnor5.0
RGSC_v3.4	7	13,292,461 - 13,292,693	UniSTS	RGSC3.4
RGSC_v3.1	7	13,292,460 - 13,292,693	RGD
Celera	7	9,816,340 - 9,816,572	UniSTS
Cytogenetic Map	7	q11	UniSTS

RH130999

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	11,733,137 - 11,733,353 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	14,906,881 - 14,907,096	NCBI	Rnor6.0
Rnor_5.0	7	15,060,903 - 15,061,118	UniSTS	Rnor5.0
RGSC_v3.4	7	13,309,047 - 13,309,262	UniSTS	RGSC3.4
Celera	7	9,832,858 - 9,833,073	UniSTS
RH 3.4 Map	7	63.7	UniSTS
Cytogenetic Map	7	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
7	5	28	113	91	90	59	19	59	6	174	67	93	36	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_173123	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U39206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000041034 ⟹ ENSRNOP00000039545

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	11,717,208 - 11,733,506 (+)	Ensembl
Rnor_6.0 Ensembl	7	14,891,001 - 14,907,305 (+)	Ensembl

RefSeq Acc Id:

NM_173123 ⟹ NP_775146

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	12,367,711 - 12,384,010 (+)	NCBI
mRatBN7.2	7	11,717,208 - 11,733,507 (+)	NCBI
Rnor_6.0	7	14,891,062 - 14,907,250 (+)	NCBI
Rnor_5.0	7	15,045,084 - 15,061,272 (+)	NCBI
RGSC_v3.4	7	13,293,080 - 13,309,416 (+)	RGD
Celera	7	9,816,959 - 9,833,227 (+)	RGD

Sequence:

show sequence

TGAGAGAAGGTGGCTGCTTAAGACCACCCATACTAAGTTAGACAGAGCACTGAACCTGGTTGCT
TATTTCTCCATAACCAACTCTCTGAAGCCAAACAGCCAGAGTGATCCTGTTGGCTTCAGACAGG
GGGGTTTCCAGGATGCCACAGTTGGACCTGTCCTGGCTGGGACTGAGGCTGGAGACATCCTTAC
CATGGCTGCTTTTGCTGCTGATCGGAGCTTCCTGGCTCTTGGTCCGTGTCTTGACTCAGACCTA
TATCTTCTACAGAACATATCAACATCTTTGTGATTTCCCTCAACCACCCAAATGGAATTGGTTC
TTGGGTCACCTGGGCATGATCACTCCCACTGAGCAAGGTCTGAAGCAGGTAACTAAGCTCGTGG
CCACCTACCCCCAGGGCTTCATGACATGGCTGGGTCCTATCCTCCCTATCATCACTCTGTGCCA
CCCTGACGTCATTCGATCTGTTCTCAGTGCCTCAGCTTCGGTTGCCCTAAAGGAAGTAATCTTC
TACAGCTTTCTGAAACCCTGGTTGGGGGATGGACTCCTGTTGAGCGATGGTGACAAGTGGAGCT
GCCACCGCCGCATGCTGACACCTGCCTTCCACTTCAACATCCTGAAACCCTATGTGAAGATTTT
CAACGACAGCACCAACATCATGCACGCCAAATGGCAGGACCTGGCCTCAGGAGGCAGCGCCCGT
CTGGACATGTTTAAGAACATCAGCCTGATGACCTTGGACAGTCTGCAGAAATGTGTCTTCAGTT
TTGATAGCAACTGCCAGGAGAAGCCCAGTGAGTATATTTCTGCCATCTTGGAGCTCAGTGCCCT
AGTGGCCAAACGGTACCAGCAGCTGCTTCTACACACAGACTCACTCTATCAGCTCACCCATAAT
GGTCGGCGCTTCCATAAGGCCTGCAAATTGGTACACAACTTCACAGACGCTGTCATCCAGGGTC
GACGACGCGCTCTCCCCAGTCAGCATGAGGATGATATCCTCAAGGCCAAGGCCAGGTCCAAAAC
TCTGGATTTCATTGATGTGCTGCTGCTGACCAAGGATGAAGATGGAAAGGAGCTGTCAGATGAA
GACATTAGAGCTGAGGCTGACACCTTCATGTTTGAAGGCCATGACACCACAGCCAGTGGGCTCT
CCTGGATCCTGTACAACCTTGCAAGGCACCCGGAATACCAGGAGCGCTGCCGGCAGGAGGTGCG
GGAGCTGCTGAGGGACCGAGAGTCTACAGAGATTGAATGGGACGACCTGGCCCAGCTGCCCTTC
CTGACCATGTGCATCAAGGAGAGTCTGCGACTGCATCCCCCAGTCACGGTCATCTCCCGTCGTT
GTACCCAAGACATCGTGCTCCCAGATGGCCGGGTCATCCCTAAAGGTGTCATCTGCATCATCAA
TATTTTCGCGACCCATCACAACCCAACTGTGTGGCCCGACCCTGAGGTCTATGATCCCTTCCGC
TTCGACCCAGAGAATATCAAGGACAGGTCACCTCTGGCTTTTATTCCCTTCTCCGCTGGGCCCA
GGAACTGCATAGGACAGACTTTTGCCATGAACGAGATGAAGGTGGCACTGGCGCTGACGCTGCT
GCGCTTCCGCGTCCTGCCGGATGACAAGGAGCCGCGCCGGAAGCCAGAGCTGATCCTGCGTGCG
GAGGGCGGACTGTGGCTGCGGGTGGAGCCACTGAGCACACAGTGACTACGTACATCTGGACGGG
TCCCACCCACCCACATACCTTTGTAGATGTCACCTGTGCCTGAGGCTCCTTGAATACCAGTAGG
GGGCTCTGGAGGACAACAGGGAACCAGCAGTTGTGGCAGGGAGGGAGATGGGGTTGGTGCCCAA
ATTCCTGACTTCATCTGGCCGTTCGTGGGCCTCTACACTGTCCTTTAGCCTAGTTGGACTTACT
CTCTTGGGCGACAGAGAGCTAAGGTAAGTGTCTAAGCAGGCTCGAGCTCACAGAATCTTTTAAA
TTGAGGTACATTTCCTGCCTTGACCTCCATTCTAATCTCAAAACTCTCATCCTGGGATTCTGAA
GTGTTTCTGTGAAAACTAAAATTTTAGGTTTATTAAACCTAACAAGTCTGCCAAAAAAAAAAAA
AAAAAA

hide sequence

RefSeq Acc Id:

XM_063263076 ⟹ XP_063119146

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	12,371,003 - 12,384,010 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_775146	(Get FASTA)	NCBI Sequence Viewer
	XP_063119146	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC52358	(Get FASTA)	NCBI Sequence Viewer
	EDL89477	(Get FASTA)	NCBI Sequence Viewer
	EDL89478	(Get FASTA)	NCBI Sequence Viewer
	EDL89479	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000039545.4
GenBank Protein	P51869	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_775146 ⟸ NM_173123

- UniProtKB:

P51869 (UniProtKB/Swiss-Prot), A6K957 (UniProtKB/TrEMBL), A0A8L2ULC7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPQLDLSWLGLRLETSLPWLLLLLIGASWLLVRVLTQTYIFYRTYQHLCDFPQPPKWNWFLGHL
GMITPTEQGLKQVTKLVATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFL
KPWLGDGLLLSDGDKWSCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQDLASGGSARLDMF
KNISLMTLDSLQKCVFSFDSNCQEKPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHNGRRF
HKACKLVHNFTDAVIQGRRRALPSQHEDDILKAKARSKTLDFIDVLLLTKDEDGKELSDEDIRA
EADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMC
IKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPE
NIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVLPDDKEPRRKPELILRAEGGL
WLRVEPLSTQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000039545 ⟸ ENSRNOT00000041034

RefSeq Acc Id:	XP_063119146 ⟸ XM_063263076
- Peptide Label:	isoform X1
- UniProtKB:	A6K958 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P51869-F1-model_v2	AlphaFold	P51869	1-522	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695074

Promoter ID:

EPDNEW_R5598

Type:

initiation region

Name:

Cyp4f4_1

Description:

cytochrome P450, family 4, subfamily f, polypeptide 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	14,891,045 - 14,891,105	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:708363	AgrOrtholog
BioCyc Gene	G2FUF-34815	BioCyc
Ensembl Genes	ENSRNOG00000032895	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000041034.5	UniProtKB/TrEMBL
Gene3D-CATH	1.10.630.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Cyt_P450	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cyt_P450_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cyt_P450_E_grp-I	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cyt_P450_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Cytochrome_P450_Monoox	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:286904	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	286904	ENTREZGENE
PANTHER	CYTOCHROME P450 4F2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CYTOCHROME P450 FAMILY 4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	p450	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Cyp4f4	PhenoGen
PRINTS	EP450I	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P450	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CYTOCHROME_P450	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000032895	RatGTEx
Superfamily-SCOP	SSF48264	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2ULC7	ENTREZGENE, UniProtKB/TrEMBL
	A6K957	ENTREZGENE, UniProtKB/TrEMBL
	A6K958	ENTREZGENE, UniProtKB/TrEMBL
	A6K959_RAT	UniProtKB/TrEMBL
	CP4F4_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-11-17	Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4		cytochrome P450 4F4	Name updated	1299863	APPROVED
2005-09-30	Cyp4f4				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)