Scaf8 (SR-related CTD-associated factor 8) - Rat Genome Database

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Pathways
Gene: Scaf8 (SR-related CTD-associated factor 8) Rattus norvegicus
Analyze
Symbol: Scaf8
Name: SR-related CTD-associated factor 8
RGD ID: 708362
Description: Enables RNA polymerase binding activity and protein domain specific binding activity. Involved in mRNA processing and transcription by RNA polymerase II. Located in nuclear matrix. Orthologous to human SCAF8 (SR-related CTD associated factor 8); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CTD-binding SR-like protein rA8; LOC245926; putative RNA-binding protein 16; Rbm16; RNA binding motif protein 16; RNA-binding motif protein 16; SR-like CTD-associated factor 8; SR-related and CTD-associated factor 8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8146,132,972 - 46,321,162 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl146,132,873 - 46,261,174 (+)EnsemblGRCr8
mRatBN7.2143,727,686 - 43,855,889 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl143,727,794 - 43,804,977 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx144,268,763 - 44,345,933 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,255,999 - 50,333,169 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,344,267 - 44,421,443 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0144,017,801 - 44,120,619 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,019,059 - 44,120,615 (+)Ensemblrn6Rnor6.0
Rnor_5.0145,348,383 - 45,451,210 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4138,098,441 - 38,173,634 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera139,365,962 - 39,443,473 (+)NCBICelera
RGSC_v3.1138,101,385 - 38,176,578 (+)NCBI
Cytogenetic Map1q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II. Patturajan M, etal., Mol Cell Biol. 1998 Apr;18(4):2406-15.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins. Yuryev A, etal., Proc Natl Acad Sci U S A 1996 Jul 9;93(14):6975-80.
Additional References at PubMed
PMID:18550522   PMID:31104839  


Genomics

Comparative Map Data
Scaf8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8146,132,972 - 46,321,162 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl146,132,873 - 46,261,174 (+)EnsemblGRCr8
mRatBN7.2143,727,686 - 43,855,889 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl143,727,794 - 43,804,977 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx144,268,763 - 44,345,933 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0150,255,999 - 50,333,169 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,344,267 - 44,421,443 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0144,017,801 - 44,120,619 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl144,019,059 - 44,120,615 (+)Ensemblrn6Rnor6.0
Rnor_5.0145,348,383 - 45,451,210 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4138,098,441 - 38,173,634 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera139,365,962 - 39,443,473 (+)NCBICelera
RGSC_v3.1138,101,385 - 38,176,578 (+)NCBI
Cytogenetic Map1q11NCBI
SCAF8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386154,733,378 - 154,834,244 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6154,733,378 - 154,842,212 (+)Ensemblhg38GRCh38
GRCh376155,054,512 - 155,155,378 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366155,096,204 - 155,196,886 (+)NCBIBuild 36Build 36hg18NCBI36
Build 346155,146,624 - 155,247,304NCBI
Celera6155,788,784 - 155,889,386 (+)NCBICelera
Cytogenetic Map6q25.2NCBI
HuRef6152,617,284 - 152,717,924 (+)NCBIHuRef
CHM1_16155,317,340 - 155,417,990 (+)NCBICHM1_1
T2T-CHM13v2.06155,935,375 - 156,036,235 (+)NCBIT2T-CHM13v2.0
Scaf8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39173,165,247 - 3,249,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl173,165,247 - 3,249,134 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38173,114,972 - 3,198,859 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl173,114,972 - 3,198,859 (+)Ensemblmm10GRCm38
MGSCv37173,114,972 - 3,198,859 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36173,069,614 - 3,155,341 (+)NCBIMGSCv36mm8
Celera173,684,798 - 3,738,527 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map171.96NCBI
Scaf8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554397,282,264 - 7,333,560 (-)Ensembl
ChiLan1.0NW_0049554397,282,264 - 7,361,855 (-)NCBIChiLan1.0ChiLan1.0
SCAF8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25174,754,445 - 175,013,932 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16172,646,004 - 172,902,437 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06152,548,019 - 152,776,596 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16158,514,265 - 158,768,718 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6158,514,265 - 158,614,407 (+)EnsemblpanPan2panpan1.1
SCAF8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1144,562,589 - 44,777,864 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl144,562,567 - 44,683,903 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha145,392,943 - 45,614,868 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0144,739,807 - 44,961,881 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl144,739,839 - 44,821,101 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1144,607,055 - 44,828,954 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0144,479,298 - 44,700,580 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0145,034,853 - 45,256,810 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Scaf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946139,802,085 - 139,979,881 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364897,059,081 - 7,231,870 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364897,059,075 - 7,289,656 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCAF8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl112,040,485 - 12,122,337 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1111,888,108 - 12,122,435 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2113,973,896 - 14,165,698 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCAF8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11382,270,422 - 82,448,887 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1382,271,029 - 82,370,850 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604054,668,476 - 54,894,702 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scaf8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247853,465,821 - 3,559,757 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247853,349,809 - 3,559,895 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Scaf8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12195,511,355 - 195,640,186 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Scaf8
1704 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:487
Count of miRNA genes:249
Interacting mature miRNAs:291
Transcripts:ENSRNOT00000065733
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)14345783787558729Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14630261591302615Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)14345783787558729Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)14630261591302615Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)14212296887122968Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)14630261591302615Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14345783787558729Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)14630261591302615Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)13070837587558729Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13456572679565726Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)14630261591302615Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)14630261591302615Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)14350995288509952Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)14212296887122968Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)14630261591302615Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)14350995288509952Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat

Markers in Region
BF400103  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2143,811,657 - 43,811,829 (+)MAPPERmRatBN7.2
Rnor_6.0144,125,923 - 44,126,094NCBIRnor6.0
Rnor_6.0144,102,359 - 44,102,530NCBIRnor6.0
Rnor_5.0145,456,512 - 45,456,683UniSTSRnor5.0
Rnor_5.0145,432,644 - 45,432,815UniSTSRnor5.0
RGSC_v3.4138,180,500 - 38,180,671UniSTSRGSC3.4
Celera139,450,153 - 39,450,324UniSTS
RH 3.4 Map1438.88UniSTS
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001428710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006227858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010062883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010062884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010062888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010062890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010062896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010062898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U49055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000065733   ⟹   ENSRNOP00000062541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl146,132,948 - 46,210,260 (+)Ensembl
mRatBN7.2 Ensembl143,727,794 - 43,804,977 (+)Ensembl
Rnor_6.0 Ensembl144,019,059 - 44,120,615 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083425   ⟹   ENSRNOP00000073484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl146,132,980 - 46,261,174 (+)Ensembl
mRatBN7.2 Ensembl143,727,984 - 43,804,977 (+)Ensembl
Rnor_6.0 Ensembl144,019,207 - 44,119,980 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109313   ⟹   ENSRNOP00000078015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl146,132,873 - 46,210,258 (+)Ensembl
mRatBN7.2 Ensembl143,727,794 - 43,804,977 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118656   ⟹   ENSRNOP00000087677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl146,158,433 - 46,261,174 (+)Ensembl
mRatBN7.2 Ensembl143,753,147 - 43,804,977 (+)Ensembl
RefSeq Acc Id: NM_139094   ⟹   NP_620794
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,133,080 - 46,210,259 (+)NCBI
mRatBN7.2143,727,794 - 43,804,978 (+)NCBI
Rnor_6.0144,019,059 - 44,120,616 (+)NCBI
Rnor_5.0145,348,383 - 45,451,210 (+)NCBI
RGSC_v3.4138,098,441 - 38,173,634 (+)RGD
Celera139,365,962 - 39,443,473 (+)RGD
Sequence:
RefSeq Acc Id: XM_006227858   ⟹   XP_006227920
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,972 - 46,210,262 (+)NCBI
mRatBN7.2143,727,686 - 43,804,981 (+)NCBI
Rnor_6.0144,017,801 - 44,120,619 (+)NCBI
Rnor_5.0145,348,383 - 45,451,210 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098275   ⟹   XP_038954203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,976 - 46,261,166 (+)NCBI
mRatBN7.2143,727,784 - 43,855,889 (+)NCBI
RefSeq Acc Id: XM_039098309   ⟹   XP_038954237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,983 - 46,210,262 (+)NCBI
mRatBN7.2143,727,784 - 43,804,981 (+)NCBI
RefSeq Acc Id: XM_039098351   ⟹   XP_038954279
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,983 - 46,210,262 (+)NCBI
mRatBN7.2143,727,784 - 43,804,981 (+)NCBI
RefSeq Acc Id: XM_039098360   ⟹   XP_038954288
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,159,293 - 46,210,262 (+)NCBI
mRatBN7.2143,754,010 - 43,804,981 (+)NCBI
RefSeq Acc Id: XM_063280810   ⟹   XP_063136880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,984 - 46,292,359 (+)NCBI
RefSeq Acc Id: XM_063280821   ⟹   XP_063136891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,983 - 46,238,437 (+)NCBI
RefSeq Acc Id: XM_063280830   ⟹   XP_063136900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,133,070 - 46,261,166 (+)NCBI
RefSeq Acc Id: XM_063280834   ⟹   XP_063136904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,133,069 - 46,210,262 (+)NCBI
RefSeq Acc Id: XM_063280845   ⟹   XP_063136915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,983 - 46,261,166 (+)NCBI
RefSeq Acc Id: XM_063280850   ⟹   XP_063136920
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,133,067 - 46,210,262 (+)NCBI
RefSeq Acc Id: XR_010062883
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,984 - 46,321,162 (+)NCBI
RefSeq Acc Id: XR_010062884
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,984 - 46,321,162 (+)NCBI
RefSeq Acc Id: XR_010062888
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,984 - 46,321,162 (+)NCBI
RefSeq Acc Id: XR_010062890
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,983 - 46,321,162 (+)NCBI
RefSeq Acc Id: XR_010062896
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,983 - 46,321,162 (+)NCBI
RefSeq Acc Id: XR_010062898
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8146,132,983 - 46,261,166 (+)NCBI
RefSeq Acc Id: NP_620794   ⟸   NM_139094
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot),   F1LPT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227920   ⟸   XM_006227858
- Peptide Label: isoform X8
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000062541   ⟸   ENSRNOT00000065733
Ensembl Acc Id: ENSRNOP00000073484   ⟸   ENSRNOT00000083425
RefSeq Acc Id: XP_038954203   ⟸   XM_039098275
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038954279   ⟸   XM_039098351
- Peptide Label: isoform X5
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot),   A0A8I5XWQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038954237   ⟸   XM_039098309
- Peptide Label: isoform X2
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038954288   ⟸   XM_039098360
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A4L7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078015   ⟸   ENSRNOT00000109313
Ensembl Acc Id: ENSRNOP00000087677   ⟸   ENSRNOT00000118656
RefSeq Acc Id: XP_063136915   ⟸   XM_063280845
- Peptide Label: isoform X5
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot),   A0A8I5XWQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136891   ⟸   XM_063280821
- Peptide Label: isoform X1
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot),   F1LPT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136880   ⟸   XM_063280810
- Peptide Label: isoform X1
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot),   F1LPT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136920   ⟸   XM_063280850
- Peptide Label: isoform X6
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063136904   ⟸   XM_063280834
- Peptide Label: isoform X4
- UniProtKB: Q63623 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063136900   ⟸   XM_063280830
- Peptide Label: isoform X3
Protein Domains
CID   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63623-F1-model_v2 AlphaFold Q63623 1-1268 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689597
Promoter ID:EPDNEW_R122
Type:multiple initiation site
Name:Scaf8_1
Description:SR-related CTD-associated factor 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R123  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0144,018,959 - 44,019,019EPDNEW
RGD ID:13689603
Promoter ID:EPDNEW_R123
Type:initiation region
Name:Scaf8_2
Description:SR-related CTD-associated factor 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R122  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0144,019,237 - 44,019,297EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708362 AgrOrtholog
BioCyc Gene G2FUF-61668 BioCyc
Ensembl Genes ENSRNOG00000016919 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000065733 ENTREZGENE
  ENSRNOT00000083425 ENTREZGENE
  ENSRNOT00000109313 ENTREZGENE
Gene3D-CATH 1.25.40.90 UniProtKB/Swiss-Prot
  3.30.70.330 UniProtKB/Swiss-Prot
InterPro CID_dom UniProtKB/Swiss-Prot
  ENTH_VHS UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
  SCAF8_RRM UniProtKB/Swiss-Prot
  SR-CTD_assoc_factor UniProtKB/Swiss-Prot
KEGG Report rno:245926 UniProtKB/Swiss-Prot
NCBI Gene 245926 ENTREZGENE
PANTHER RNA PROCESSING PROTEIN LD23810P UniProtKB/Swiss-Prot
  SR-RELATED CTD ASSOCIATED FACTOR 8 UniProtKB/Swiss-Prot
Pfam CTD_bind UniProtKB/Swiss-Prot
  RRM_1 UniProtKB/Swiss-Prot
PhenoGen Scaf8 PhenoGen
PROSITE CID UniProtKB/Swiss-Prot
  RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016919 RatGTEx
SMART RPR UniProtKB/Swiss-Prot
  RRM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48464 UniProtKB/Swiss-Prot
  SSF54928 UniProtKB/Swiss-Prot
UniProt A0A0G2K5M7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5XWQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4L7 ENTREZGENE, UniProtKB/TrEMBL
  F1LPT8 ENTREZGENE, UniProtKB/TrEMBL
  Q63623 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Scaf8  SR-related CTD-associated factor 8  Rbm16  RNA binding motif protein 16  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rbm16  RNA binding motif protein 16  LOC245926    Symbol updated 1299863 APPROVED