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Gene: Pnck (pregnancy up-regulated nonubiquitous CaM kinase) Rattus norvegicus

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Symbol:

Pnck

Name:

pregnancy up-regulated nonubiquitous CaM kinase

RGD ID:

69249

Description:

Enables calcium/calmodulin-dependent protein kinase activity. Predicted to be involved in signal transduction. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human PNCK (pregnancy up-regulated nonubiquitous CaM kinase); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

calcium/calmodulin-dependent protein kinase 1 beta; calcium/calmodulin-dependent protein kinase 1, beta; calcium/calmodulin-dependent protein kinase type 1B; caM kinase I beta; caM kinase IB; caM-KI beta; Camk1b; caMKI-beta; LOC100360379; pregnancy up-regulated non-ubiquitously-expressed CaM kinase homolog; pregnancy upregulated non-ubiquitously expressed CaM kinase; Protein Kinase-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	156,520,751 - 156,524,828 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	156,520,753 - 156,525,352 (-)	Ensembl				GRCr8
mRatBN7.2	X	151,369,406 - 151,373,508 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	151,369,410 - 151,373,446 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	153,510,581 - 153,514,481 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	157,073,812 - 157,077,712 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	154,745,644 - 154,749,544 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	157,150,071 - 157,154,558 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	157,150,655 - 157,154,555 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	152,900,009 - 152,904,076 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	45,741,127 - 45,741,920 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	136,516,497 - 136,520,397 (+)	NCBI		Celera
RGSC_v3.1	X	159,628,959 - 159,632,860 (-)	NCBI
Cytogenetic Map	X	q37	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

actinomycin D (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

amitrole (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

choline (ISO)

chrysene (ISO)

cisplatin (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

ethanol (EXP,ISO)

fipronil (EXP)

folic acid (ISO)

L-methionine (ISO)

lead(0) (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

methylmercury chloride (ISO)

Nutlin-3 (ISO)

PCB138 (ISO)

phenylmercury acetate (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

Soman (EXP)

sulforaphane (ISO)

testosterone (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

signal transduction (IBA)

Cellular Component

cytoplasm (IBA,IEA)

nucleus (IEA)

Molecular Function

ATP binding (IEA)

calcium/calmodulin-dependent protein kinase activity (IBA,IDA,IEA)

calmodulin binding (IBA,IEA)

kinase activity (IEA)

nucleotide binding (IEA)

protein kinase activity (IEA)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

transferase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Isoform-specific activation and structural diversity of calmodulin kinase I.	Naito Y, etal., J Biol Chem 1997 Dec 19;272(51):32704-8.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
8.	Differential regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinase isoforms.	Tokumitsu H, etal., Biochemistry 2001 Nov 20;40(46):13925-32.
9.	Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin-dependent protein kinase I isoforms.	Yokokura H, etal., Biochim Biophys Acta 1997 Mar 7;1338(1):8-12.

Additional References at PubMed

PMID:11264466	PMID:19292454	PMID:22871113

Genomics

Comparative Map Data

Pnck
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	156,520,751 - 156,524,828 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	156,520,753 - 156,525,352 (-)	Ensembl				GRCr8
mRatBN7.2	X	151,369,406 - 151,373,508 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	151,369,410 - 151,373,446 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	153,510,581 - 153,514,481 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	157,073,812 - 157,077,712 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	154,745,644 - 154,749,544 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	157,150,071 - 157,154,558 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	157,150,655 - 157,154,555 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	152,900,009 - 152,904,076 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	45,741,127 - 45,741,920 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	136,516,497 - 136,520,397 (+)	NCBI		Celera
RGSC_v3.1	X	159,628,959 - 159,632,860 (-)	NCBI
Cytogenetic Map	X	q37	NCBI

PNCK
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	153,669,733 - 153,687,771 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	153,669,730 - 153,689,033 (-)	Ensembl			hg38	GRCh38
GRCh37	X	152,935,188 - 152,953,226 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	152,588,417 - 152,592,974 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	X	153,168,872 - 153,173,500 (-)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	141,592,549 - 141,597,177 (-)	NCBI		HuRef
CHM1_1	X	152,809,688 - 152,814,316 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	151,943,398 - 151,961,436 (-)	NCBI		T2T-CHM13v2.0

Pnck
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	72,699,598 - 72,703,723 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	72,699,600 - 72,703,723 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	73,655,992 - 73,660,117 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	73,655,994 - 73,660,117 (-)	Ensembl			mm10	GRCm38
MGSCv37	X	70,901,333 - 70,905,167 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	69,908,714 - 69,912,548 (-)	NCBI		MGSCv36	mm8
Celera	X	64,909,809 - 64,913,643 (-)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	37.38	NCBI

Pnck
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955580	401,297 - 405,065 (-)	Ensembl
ChiLan1.0	NW_004955580	401,411 - 406,663 (-)	NCBI	ChiLan1.0	ChiLan1.0

PNCK
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	153,709,882 - 153,714,516 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	153,713,486 - 153,718,120 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	143,220,029 - 143,224,659 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	153,106,491 - 153,123,897 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	153,106,491 - 153,123,897 (-)	Ensembl			panPan2	panpan1.1

PNCK
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	121,489,041 - 121,491,356 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	121,489,040 - 121,491,431 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	106,819,067 - 106,822,956 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	124,631,200 - 124,635,086 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	124,631,204 - 124,635,176 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	120,400,661 - 120,404,547 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	122,915,659 - 122,919,533 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	122,677,778 - 122,681,665 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pnck
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	118,815,663 - 118,819,645 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936809	553,431 - 557,427 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936809	553,438 - 557,385 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PNCK
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	124,425,872 - 124,429,261 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	124,425,867 - 124,430,000 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	141,989,364 - 141,993,498 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PNCK
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	128,099,736 - 128,104,348 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	128,099,682 - 128,103,121 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666065	65,961,824 - 65,966,436 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pnck
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624946	376,856 - 391,192 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624946	377,454 - 391,055 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pnck
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	129,276,468 - 129,280,278 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	343
Count of miRNA genes:	218
Interacting mature miRNAs:	252
Transcripts:	ENSRNOT00000024227
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	105359969	157758123	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	118973754	157758123	Rat

Markers in Region

RH137751

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	151,369,452 - 151,369,587 (-)	MAPPER	mRatBN7.2
Rnor_6.0	X	157,154,378 - 157,154,512	NCBI	Rnor6.0
Rnor_5.0	1	152,903,895 - 152,904,029	UniSTS	Rnor5.0
RGSC_v3.4	X	159,555,568 - 159,555,702	UniSTS	RGSC3.4
Celera	1	136,520,220 - 136,520,354	UniSTS
RH 3.4 Map	1	1646.0	UniSTS
Cytogenetic Map	X	q37	UniSTS

UniSTS:546957

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	151,369,441 - 151,370,707 (-)	MAPPER	mRatBN7.2
Rnor_6.0	X	157,153,258 - 157,154,523	NCBI	Rnor6.0
Rnor_5.0	1	152,902,775 - 152,904,040	UniSTS	Rnor5.0
Celera	1	136,519,100 - 136,520,365	UniSTS
Cytogenetic Map	X	q37	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	9	53	140	83	79	57	20	57	6	212	97	5	122	43	81	22	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229573	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229575	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008773628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB004267	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC096338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474099	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D86556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000090795 ⟹ ENSRNOP00000074179

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	156,520,753 - 156,524,653 (-)	Ensembl
mRatBN7.2 Ensembl	X	151,369,410 - 151,373,310 (-)	Ensembl
Rnor_6.0 Ensembl	X	157,150,655 - 157,154,555 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095467 ⟹ ENSRNOP00000094811

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	156,520,753 - 156,524,789 (-)	Ensembl
mRatBN7.2 Ensembl	X	151,369,410 - 151,373,446 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000126122 ⟹ ENSRNOP00000099713

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	156,520,753 - 156,525,352 (-)	Ensembl

RefSeq Acc Id:

NM_017275 ⟹ NP_058971

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	156,520,753 - 156,524,653 (-)	NCBI
mRatBN7.2	X	151,369,410 - 151,373,310 (-)	NCBI
Rnor_6.0	X	157,150,655 - 157,154,555 (+)	NCBI
Rnor_5.0	1	152,900,009 - 152,904,076 (+)	NCBI
RGSC_v3.4	X	45,741,127 - 45,741,920 (+)	RGD
Celera	1	136,516,497 - 136,520,397 (+)	NCBI

Sequence:

show sequence

AAGGCATCTTACGTCCGCAGCCCACCACCCTCACACACACCTGTGACGCCCGGCGCGCCCCCCT
GCCCGCACGCGCACAGCCCACGCAGCTCTGGACACAGGCGGCTGAGGTTGCGGAGTCCCCCCAC
GCTGAGGCGCCAGGGGCCAAGCAGCGATTAGGGGGCTGCGTGGGTGGCTGTGGTCGTGACAGGT
GGCTGCAAGCAGGGTCGCAGACATGCTGCTGCTCAAGAAACAGACGGAGGACATCAGCAGTGTC
TATGAGATCCGGGAGAAGCTGGGCTCGGGTGCCTTCTCTGAGGTGATGCTGGCCCAGGAAAGGG
GCTCTGCTCATCTTGTGGCCCTCAAGTGCATTCCCAAGAAAGCACTTCGGGGCAAGGAGGCCCT
GGTGGAGAATGAGATCGCAGTACTCCGCAGGATTAGCCACCCCAACATTGTGGCTCTGGAGGAC
GTCCACGAGAGCCCTTCCCATCTCTACTTGGCCATGGAGCTGGTAACAGGTGGTGAACTGTTTG
ACCGAATCATGGAGCGGGGCTCCTACACAGAGAAGGATGCGAGCCACCTTGTAGGGCAGGTCCT
TGGTGCTGTCTCCTACCTTCATAGCCTGGGCATCGTGCACCGGGACCTCAAGCCTGAAAACCTC
CTCTATGCCACACCTTTTGAGGACTCCAAGATCATGGTCTCTGACTTTGGCCTGTCCAAAATTC
AAGCTGGCAACATGCTAGGCACAGCCTGTGGGACCCCAGGATATGTGGCCCCAGAGCTCCTGGA
GCAGAAACCCTACGGGAAGGCCGTAGATGTGTGGGCCCTGGGTGTCATCTCCTACATCCTGCTG
TGTGGGTACCCCCCCTTCTATGATGAGAGCGATCCTGAACTCTTCAGCCAGATTCTGAGGGCCA
GCTACGAGTTTGACTCTCCCTTTTGGGATGACATCTCAGAATCAGCCAAAGACTTCATTCGGCA
CCTTCTGGAACGTGATCCCCAGAAGAGGTTCACCTGCCAACAGGCCTTACAGCATCTCTGGATC
TCTGGGGATGCAGCCTTGGACAGGGACATCCTAGGTTCTGTCAGTGAGCAGATCCAGAAGAATT
TTGCCAGGACCCACTGGAAGCGTGCATTCAATGCCACATCATTCCTACGTCACATCCGTAAGCT
GGGACAGAGCCCAGAGGGTGAGGAGGCCTCCAGGCAGGGTATGACCCGTCACAGCCACCCAGGC
CTTGGGACTAGCCAGTCTCCCAAGTGGTGACAACCAGGTGGATGCCAAGGAAGGCCAAGTGGAC
TGACTCCTAGCTTTTCTTTCCTCCAGCCCTTTTGATCTCCTTCCCTGATCCTTGTCCCCCGGAC
TGGCCTCTGTTGGAAAGTCCAAGACCGTGGGTGTGATGCATGGCACTGGGGTATGGGGCTTCCC
AAGTATGTCCCCAGCCTCTGTCCTTTGTTGCTGCCACCCTCTATGGAAACTGAGGAGGTATTCA
AAAATGGATTTGGGGCCATCCTTCCTGCACCTTGCACGCACATATGCATTGCGTGGCTGTTCTG
TGCTTTGCTGACTGTGGGTGGTCCTGCTTGTGTTGTAGCCCTTTAGTTCCTCCTCTTTCCAACC
AATAAAGACAAACAGAAC

hide sequence

RefSeq Acc Id:

XM_006229572 ⟹ XP_006229634

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	156,520,751 - 156,524,760 (-)	NCBI
mRatBN7.2	X	151,369,406 - 151,373,373 (-)	NCBI
Rnor_6.0	X	157,150,604 - 157,154,558 (+)	NCBI
Rnor_5.0	1	152,900,009 - 152,904,076 (+)	NCBI

Sequence:

show sequence

ACTGGGGGCAAACAGGCGAGCGGAACCGGCGGGCCGGGGCGTACAGGGACCAAGGCATCTTAGC
TCCGCAGCCCACCACCCTCACACACACCTGTGACGCCCGGCGCGCCCCCCTGCCCGCACGCGCA
CAGCCCACGCAGCTCTGGACACAGGCGGCTGAGGTTGCGGAGTCCCCCCACGCTGAGGCGCCAG
GGGCCAAGCAGCGATTAGGGGGCTGCGTGGGTGGCTGTGGTCGTGACAGGTGGCTGCAAGCAGG
GTCGCAGGTGCATTCGAGCGGGTTGGTGACCTACGTGGTGTGTGCTTGAGCTGAGCCACTATGG
AAGACATGCTGCTGCTCAAGAAACAGACGGAGGACATCAGCAGTGTCTATGAGATCCGGGAGAA
GCTGGGCTCGGGTGCCTTCTCTGAGGTGATGCTGGCCCAGGAAAGGGGCTCTGCTCATCTTGTG
GCCCTCAAGTGCATTCCCAAGAAAGCACTTCGGGGCAAGGAGGCCCTGGTGGAGAATGAGATCG
CAGTACTCCGCAGGATTAGCCACCCCAACATTGTGGCTCTGGAGGACGTCCACGAGAGCCCTTC
CCATCTCTACTTGGCCATGGAGCTGGTAACAGGTGGTGAACTGTTTGACCGAATCATGGAGCGG
GGCTCCTACACAGAGAAGGATGCGAGCCACCTTGTAGGGCAGGTCCTTGGTGCTGTCTCCTACC
TTCATAGCCTGGGCATCGTGCACCGGGACCTCAAGCCTGAAAACCTCCTCTATGCCACACCTTT
TGAGGACTCCAAGATCATGGTCTCTGACTTTGGCCTGTCCAAAATTCAAGCTGGCAACATGCTA
GGCACAGCCTGTGGGACCCCAGGATATGTGGCCCCAGAGCTCCTGGAGCAGAAACCCTACGGGA
AGGCCGTAGATGTGTGGGCCCTGGGTGTCATCTCCTACATCCTGCTGTGTGGGTACCCCCCCTT
CTATGATGAGAGCGATCCTGAACTCTTCAGCCAGATTCTGAGGGCCAGCTACGAGTTTGACTCT
CCCTTTTGGGATGACATCTCAGAATCAGCCAAAGACTTCATTCGGCACCTTCTGGAACGTGATC
CCCAGAAGAGGTTCACCTGCCAACAGGCCTTACAGCATCTCTGGATCTCTGGGGATGCAGCCTT
GGACAGGGACATCCTAGGTTCTGTCAGTGAGCAGATCCAGAAGAATTTTGCCAGGACCCACTGG
AAGCGTGCATTCAATGCCACATCATTCCTACGTCACATCCGTAAGCTGGGACAGAGCCCAGAGG
GTGAGGAGGCCTCCAGGCAGGGTATGACCCGTCACAGCCACCCAGGCCTTGGGACTAGCCAGTC
TCCCAAGTGGTGACAACCAGGTGGATGCCAAGGAAGGCCAAGTGGACTGACTCCTAGCTTTTCT
TTCCTCCAGCCCTTTTGATCTCCTTCCCTGATCCTTGTCCCCCGGACTGGCCTCTGTTGGAAAG
TCCAAGACCGTGGGTGTGATGCATGGCACTGGGGTATGGGGCTTCCCAAGTATGTCCCCAGCCT
CTGTCCTTTGTTGCTGCCACCCTCTATGGAAACTGAGGAGGTATTCAAAAATGGATTTGGGGGC
CATCCTTCCTGCACCTTGCACGCACATATGCATTGCGTGGCTGTTCTGTGCTTTGCTGACTGTG
GGTGGTCCTGCTTGTGTTGTAGCCCTTTAGTTCCTCCTCTTTCCAACCAATAAAGACAAACAGA
ACAAT

hide sequence

RefSeq Acc Id:

XM_006229573 ⟹ XP_006229635

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	156,520,751 - 156,524,828 (-)	NCBI
mRatBN7.2	X	151,369,406 - 151,373,508 (-)	NCBI
Rnor_6.0	X	157,150,511 - 157,154,558 (+)	NCBI
Rnor_5.0	1	152,900,009 - 152,904,076 (+)	NCBI

Sequence:

show sequence

GCTCGGCGACACAACAGCTACTGCGCTAGGAGACATTGCGGCGGCGGTGGCGGCGTTGGCAGCA
GCTGCAGACATGCTGCTGCTCAAGAAACAGACGGAGGACATCAGCAGTGTCTATGAGATCCGGG
AGAAGCTGGGCTCGGGTGCCTTCTCTGAGGTGATGCTGGCCCAGGAAAGGGGCTCTGCTCATCT
TGTGGCCCTCAAGTGCATTCCCAAGAAAGCACTTCGGGGCAAGGAGGCCCTGGTGGAGAATGAG
ATCGCAGTACTCCGCAGGATTAGCCACCCCAACATTGTGGCTCTGGAGGACGTCCACGAGAGCC
CTTCCCATCTCTACTTGGCCATGGAGCTGGTAACAGGTGGTGAACTGTTTGACCGAATCATGGA
GCGGGGCTCCTACACAGAGAAGGATGCGAGCCACCTTGTAGGGCAGGTCCTTGGTGCTGTCTCC
TACCTTCATAGCCTGGGCATCGTGCACCGGGACCTCAAGCCTGAAAACCTCCTCTATGCCACAC
CTTTTGAGGACTCCAAGATCATGGTCTCTGACTTTGGCCTGTCCAAAATTCAAGCTGGCAACAT
GCTAGGCACAGCCTGTGGGACCCCAGGATATGTGGCCCCAGAGCTCCTGGAGCAGAAACCCTAC
GGGAAGGCCGTAGATGTGTGGGCCCTGGGTGTCATCTCCTACATCCTGCTGTGTGGGTACCCCC
CCTTCTATGATGAGAGCGATCCTGAACTCTTCAGCCAGATTCTGAGGGCCAGCTACGAGTTTGA
CTCTCCCTTTTGGGATGACATCTCAGAATCAGCCAAAGACTTCATTCGGCACCTTCTGGAACGT
GATCCCCAGAAGAGGTTCACCTGCCAACAGGCCTTACAGCATCTCTGGATCTCTGGGGATGCAG
CCTTGGACAGGGACATCCTAGGTTCTGTCAGTGAGCAGATCCAGAAGAATTTTGCCAGGACCCA
CTGGAAGCGTGCATTCAATGCCACATCATTCCTACGTCACATCCGTAAGCTGGGACAGAGCCCA
GAGGGTGAGGAGGCCTCCAGGCAGGGTATGACCCGTCACAGCCACCCAGGCCTTGGGACTAGCC
AGTCTCCCAAGTGGTGACAACCAGGTGGATGCCAAGGAAGGCCAAGTGGACTGACTCCTAGCTT
TTCTTTCCTCCAGCCCTTTTGATCTCCTTCCCTGATCCTTGTCCCCCGGACTGGCCTCTGTTGG
AAAGTCCAAGACCGTGGGTGTGATGCATGGCACTGGGGTATGGGGCTTCCCAAGTATGTCCCCA
GCCTCTGTCCTTTGTTGCTGCCACCCTCTATGGAAACTGAGGAGGTATTCAAAAATGGATTTGG
GGGCCATCCTTCCTGCACCTTGCACGCACATATGCATTGCGTGGCTGTTCTGTGCTTTGCTGAC
TGTGGGTGGTCCTGCTTGTGTTGTAGCCCTTTAGTTCCTCCTCTTTCCAACCAATAAAGACAAA
CAGAACAAT

hide sequence

RefSeq Acc Id:

XM_006229575 ⟹ XP_006229637

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	156,520,751 - 156,524,713 (-)	NCBI
mRatBN7.2	X	151,369,406 - 151,373,373 (-)	NCBI
Rnor_6.0	X	157,150,604 - 157,154,558 (+)	NCBI
Rnor_5.0	1	152,900,009 - 152,904,076 (+)	NCBI

Sequence:

show sequence

ACTGGGGGCAAACAGGCGAGCGGAACCGGCGGGCCGGGGCGTACAGGGACCAAGGCATCTTAGC
TCCGCAGCCCACCACCCTCACACACACCTGTGACGCCCGGCGCGCCCCCCTGCCCGCACGCGCA
CAGCCCACGCAGCTCTGGACACAGGCGGCTGAGGTTGCGGAGTCCCCCCACGCTGAGGCGCCAG
GGGCCAAGCAGCGATTAGGGGGCTGCGTGGGTGGCTGTGGTCGTGACAGGTGGCTGCAAGCAGG
GTCGCAGGTGCATTCGAGCGGACATGCTGCTGCTCAAGAAACAGACGGAGGACATCAGCAGTGT
CTATGAGATCCGGGAGAAGCTGGGCTCGGGTGCCTTCTCTGAGGTGATGCTGGCCCAGGAAAGG
GGCTCTGCTCATCTTGTGGCCCTCAAGTGCATTCCCAAGAAAGCACTTCGGGGCAAGGAGGCCC
TGGTGGAGAATGAGATCGCAGTACTCCGCAGGATTAGCCACCCCAACATTGTGGCTCTGGAGGA
CGTCCACGAGAGCCCTTCCCATCTCTACTTGGCCATGGAGCTGGTAACAGGTGGTGAACTGTTT
GACCGAATCATGGAGCGGGGCTCCTACACAGAGAAGGATGCGAGCCACCTTGTAGGGCAGGTCC
TTGGTGCTGTCTCCTACCTTCATAGCCTGGGCATCGTGCACCGGGACCTCAAGCCTGAAAACCT
CCTCTATGCCACACCTTTTGAGGACTCCAAGATCATGGTCTCTGACTTTGGCCTGTCCAAAATT
CAAGCTGGCAACATGCTAGGCACAGCCTGTGGGACCCCAGGATATGTGGCCCCAGAGCTCCTGG
AGCAGAAACCCTACGGGAAGGCCGTAGATGTGTGGGCCCTGGGTGTCATCTCCTACATCCTGCT
GTGTGGGTACCCCCCCTTCTATGATGAGAGCGATCCTGAACTCTTCAGCCAGATTCTGAGGGCC
AGCTACGAGTTTGACTCTCCCTTTTGGGATGACATCTCAGAATCAGCCAAAGACTTCATTCGGC
ACCTTCTGGAACGTGATCCCCAGAAGAGGTTCACCTGCCAACAGGCCTTACAGCATCTCTGGAT
CTCTGGGGATGCAGCCTTGGACAGGGACATCCTAGGTTCTGTCAGTGAGCAGATCCAGAAGAAT
TTTGCCAGGACCCACTGGAAGCGTGCATTCAATGCCACATCATTCCTACGTCACATCCGTAAGC
TGGGACAGAGCCCAGAGGGTGAGGAGGCCTCCAGGCAGGGTATGACCCGTCACAGCCACCCAGG
CCTTGGGACTAGCCAGTCTCCCAAGTGGTGACAACCAGGTGGATGCCAAGGAAGGCCAAGTGGA
CTGACTCCTAGCTTTTCTTTCCTCCAGCCCTTTTGATCTCCTTCCCTGATCCTTGTCCCCCGGA
CTGGCCTCTGTTGGAAAGTCCAAGACCGTGGGTGTGATGCATGGCACTGGGGTATGGGGCTTCC
CAAGTATGTCCCCAGCCTCTGTCCTTTGTTGCTGCCACCCTCTATGGAAACTGAGGAGGTATTC
AAAAATGGATTTGGGGGCCATCCTTCCTGCACCTTGCACGCACATATGCATTGCGTGGCTGTTC
TGTGCTTTGCTGACTGTGGGTGGTCCTGCTTGTGTTGTAGCCCTTTAGTTCCTCCTCTTTCCAA
CCAATAAAGACAAACAGAACAAT

hide sequence

RefSeq Acc Id:

XM_008773628 ⟹ XP_008771850

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	156,520,751 - 156,524,298 (-)	NCBI
mRatBN7.2	X	151,369,406 - 151,372,964 (-)	NCBI
Rnor_6.0	X	157,150,944 - 157,154,558 (+)	NCBI

Sequence:

show sequence

CAAGGGCCCTATGGGTGGAGGTGGGTCTCATGAACCAGGATCAGAGTGTATGGAGCCTTCTGGA
AAATAGTCGGCAGTTCTGGCTCGATGTGTGGAGGCAGAAAAGGGGTGTCATAGTGTTGGTAGCC
AACATTAGACATGCTGCTGCTCAAGAAACAGACGGAGGACATCAGCAGTGTCTATGAGATCCGG
GAGAAGCTGGGCTCGGGTGCCTTCTCTGAGGTGATGCTGGCCCAGGAAAGGGGCTCTGCTCATC
TTGTGGCCCTCAAGTGCATTCCCAAGAAAGCACTTCGGGGCAAGGAGGCCCTGGTGGAGAATGA
GATCGCAGTACTCCGCAGGATTAGCCACCCCAACATTGTGGCTCTGGAGGACGTCCACGAGAGC
CCTTCCCATCTCTACTTGGCCATGGAGCTGGTAACAGGTGGTGAACTGTTTGACCGAATCATGG
AGCGGGGCTCCTACACAGAGAAGGATGCGAGCCACCTTGTAGGGCAGGTCCTTGGTGCTGTCTC
CTACCTTCATAGCCTGGGCATCGTGCACCGGGACCTCAAGCCTGAAAACCTCCTCTATGCCACA
CCTTTTGAGGACTCCAAGATCATGGTCTCTGACTTTGGCCTGTCCAAAATTCAAGCTGGCAACA
TGCTAGGCACAGCCTGTGGGACCCCAGGATATGTGGCCCCAGAGCTCCTGGAGCAGAAACCCTA
CGGGAAGGCCGTAGATGTGTGGGCCCTGGGTGTCATCTCCTACATCCTGCTGTGTGGGTACCCC
CCCTTCTATGATGAGAGCGATCCTGAACTCTTCAGCCAGATTCTGAGGGCCAGCTACGAGTTTG
ACTCTCCCTTTTGGGATGACATCTCAGAATCAGCCAAAGACTTCATTCGGCACCTTCTGGAACG
TGATCCCCAGAAGAGGTTCACCTGCCAACAGGCCTTACAGCATCTCTGGATCTCTGGGGATGCA
GCCTTGGACAGGGACATCCTAGGTTCTGTCAGTGAGCAGATCCAGAAGAATTTTGCCAGGACCC
ACTGGAAGCGTGCATTCAATGCCACATCATTCCTACGTCACATCCGTAAGCTGGGACAGAGCCC
AGAGGGTGAGGAGGCCTCCAGGCAGGGTATGACCCGTCACAGCCACCCAGGCCTTGGGACTAGC
CAGTCTCCCAAGTGGTGACAACCAGGTGGATGCCAAGGAAGGCCAAGTGGACTGACTCCTAGCT
TTTCTTTCCTCCAGCCCTTTTGATCTCCTTCCCTGATCCTTGTCCCCCGGACTGGCCTCTGTTG
GAAAGTCCAAGACCGTGGGTGTGATGCATGGCACTGGGGTATGGGGCTTCCCAAGTATGTCCCC
AGCCTCTGTCCTTTGTTGCTGCCACCCTCTATGGAAACTGAGGAGGTATTCAAAAATGGATTTG
GGGGCCATCCTTCCTGCACCTTGCACGCACATATGCATTGCGTGGCTGTTCTGTGCTTTGCTGA
CTGTGGGTGGTCCTGCTTGTGTTGTAGCCCTTTAGTTCCTCCTCTTTCCAACCAATAAAGACAA
ACAGAACAAT

hide sequence

RefSeq Acc Id:

XM_063279872 ⟹ XP_063135942

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	156,520,751 - 156,524,767 (-)	NCBI

RefSeq Acc Id:

XM_063279873 ⟹ XP_063135943

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	156,520,751 - 156,524,717 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_058971	(Get FASTA)	NCBI Sequence Viewer
	XP_006229634	(Get FASTA)	NCBI Sequence Viewer
	XP_006229635	(Get FASTA)	NCBI Sequence Viewer
	XP_006229637	(Get FASTA)	NCBI Sequence Viewer
	XP_008771850	(Get FASTA)	NCBI Sequence Viewer
	XP_063135942	(Get FASTA)	NCBI Sequence Viewer
	XP_063135943	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA19879	(Get FASTA)	NCBI Sequence Viewer
	BAA28263	(Get FASTA)	NCBI Sequence Viewer
	EDL85037	(Get FASTA)	NCBI Sequence Viewer
	EDL85038	(Get FASTA)	NCBI Sequence Viewer
	EDL85039	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074179
	ENSRNOP00000074179.1
	ENSRNOP00000094811
	ENSRNOP00000094811.1
	ENSRNOP00000099713
GenBank Protein	O70150	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_058971 ⟸ NM_017275

- UniProtKB:

O08767 (UniProtKB/Swiss-Prot), O70150 (UniProtKB/Swiss-Prot), A6KRX3 (UniProtKB/TrEMBL), A6KRX2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAV
LRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLH
SLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKA
VDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQ
KRFTCQQALQHLWISGDAALDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGE
EASRQGMTRHSHPGLGTSQSPKW

hide sequence

RefSeq Acc Id:	XP_006229635 ⟸ XM_006229573
- Peptide Label:	isoform X2
- UniProtKB:	O08767 (UniProtKB/Swiss-Prot), O70150 (UniProtKB/Swiss-Prot), A6KRX3 (UniProtKB/TrEMBL), A6KRX2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAV LRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLH SLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKA VDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQ KRFTCQQALQHLWISGDAALDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGE EASRQGMTRHSHPGLGTSQSPKW hide sequence

RefSeq Acc Id:	XP_006229634 ⟸ XM_006229572
- Peptide Label:	isoform X1
- UniProtKB:	A6KRX1 (UniProtKB/TrEMBL), A6KRX2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEDMLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENE IAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVS YLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPY GKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLER DPQKRFTCQQALQHLWISGDAALDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSP EGEEASRQGMTRHSHPGLGTSQSPKW hide sequence

RefSeq Acc Id:	XP_006229637 ⟸ XM_006229575
- Peptide Label:	isoform X2
- UniProtKB:	O08767 (UniProtKB/Swiss-Prot), O70150 (UniProtKB/Swiss-Prot), A6KRX3 (UniProtKB/TrEMBL), A6KRX2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAV LRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLH SLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKA VDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQ KRFTCQQALQHLWISGDAALDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGE EASRQGMTRHSHPGLGTSQSPKW hide sequence

RefSeq Acc Id:	XP_008771850 ⟸ XM_008773628
- Peptide Label:	isoform X2
- UniProtKB:	O08767 (UniProtKB/Swiss-Prot), O70150 (UniProtKB/Swiss-Prot), A6KRX3 (UniProtKB/TrEMBL), A6KRX2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAV LRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLH SLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKA VDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQ KRFTCQQALQHLWISGDAALDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGE EASRQGMTRHSHPGLGTSQSPKW hide sequence

Ensembl Acc Id:

ENSRNOP00000074179 ⟸ ENSRNOT00000090795

Ensembl Acc Id:

ENSRNOP00000094811 ⟸ ENSRNOT00000095467

RefSeq Acc Id:	XP_063135942 ⟸ XM_063279872
- Peptide Label:	isoform X2
- UniProtKB:	O70150 (UniProtKB/Swiss-Prot), O08767 (UniProtKB/Swiss-Prot), A6KRX2 (UniProtKB/TrEMBL), A6KRX3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135943 ⟸ XM_063279873
- Peptide Label:	isoform X3
- UniProtKB:	A6KRX2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000099713 ⟸ ENSRNOT00000126122

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O70150-F1-model_v2	AlphaFold	O70150	1-343	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69249	AgrOrtholog
BioCyc Gene	G2FUF-669	BioCyc
Ensembl Genes	ENSRNOG00000058317	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000090795	ENTREZGENE
	ENSRNOT00000090795.2	UniProtKB/Swiss-Prot
	ENSRNOT00000095467	ENTREZGENE
	ENSRNOT00000095467.1	UniProtKB/Swiss-Prot
	ENSRNOT00000126122	ENTREZGENE
Gene3D-CATH	Phosphorylase Kinase, domain 1	UniProtKB/Swiss-Prot
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot
InterPro	CaMKI_beta_STKc	UniProtKB/Swiss-Prot
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot
	Prot_kinase_dom	UniProtKB/Swiss-Prot
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot
KEGG Report	rno:29660	UniProtKB/Swiss-Prot
NCBI Gene	29660	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN KINASE	UniProtKB/Swiss-Prot
Pfam	Pkinase	UniProtKB/Swiss-Prot
PhenoGen	Pnck	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000058317	RatGTEx
SMART	S_TKc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot
TIGR	TC231859
UniProt	A0ABK0L641_RAT	UniProtKB/TrEMBL
	A6KRX1	ENTREZGENE, UniProtKB/TrEMBL
	A6KRX2	ENTREZGENE, UniProtKB/TrEMBL
	A6KRX3	ENTREZGENE, UniProtKB/TrEMBL
	KCC1B_RAT	UniProtKB/Swiss-Prot
	O08767	ENTREZGENE
	O70150	ENTREZGENE
UniProt Secondary	O08767	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-11-22	Pnck	pregnancy up-regulated nonubiquitous CaM kinase	Pnck	pregnancy upregulated non-ubiquitously expressed CaM kinase	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-04-17	Pnck	pregnancy upregulated non-ubiquitously expressed CaM kinase	LOC100360379	Protein Kinase-like	Data merged from RGD:2322274	737654	PROVISIONAL
2010-05-06	LOC100360379	Protein Kinase-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2003-04-09	Pnck	pregnancy upregulated non-ubiquitously expressed CaM kinase	Camk1b	calcium/calmodulin-dependent protein kinase 1, beta	Symbol and Name updated	629477	APPROVED
2002-06-10	Camk1b	calcium/calmodulin-dependent protein kinase 1, beta			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	alternatively spliced form CaM kiinase Ibeta2 is exprssed in cerebrum and cerebellum; alternatively spliced form CaM kinase IbetaI is expressed in liver, heart, lung, and kidney, spleen, and testis	68883

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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