Lsr (lipolysis stimulated lipoprotein receptor) - Rat Genome Database

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Gene: Lsr (lipolysis stimulated lipoprotein receptor) Rattus norvegicus
Analyze
Symbol: Lsr
Name: lipolysis stimulated lipoprotein receptor
RGD ID: 69236
Description: Predicted to enable fatty acid binding activity and triglyceride binding activity. Involved in regulation of lipid metabolic process. Predicted to be located in tight junction. Predicted to be part of chylomicron; low-density lipoprotein particle; and very-low-density lipoprotein particle. Predicted to be active in plasma membrane and tricellular tight junction. Orthologous to human LSR (lipolysis stimulated lipoprotein receptor); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lipolysis-stimulated lipoprotein receptor; lipolysis-stimulated receptor; lipolysis-stimulated remnant receptor; Lisch7; liver-specific bHLH-Zip transcription factor; liver-specific bHLH-Zip transcription factor 7; MGC124592
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,313,830 - 95,329,471 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,313,033 - 95,329,354 (-)EnsemblGRCr8
mRatBN7.2186,185,769 - 86,201,952 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,186,431 - 86,201,952 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx191,606,550 - 91,622,061 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,072,713 - 100,088,227 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,364,848 - 93,380,361 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,383,515 - 89,399,041 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,383,519 - 89,399,041 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,539,042 - 90,554,631 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,993,858 - 86,009,382 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,555,106 - 80,570,632 (-)NCBICelera
RGSC_v3.1186,071,970 - 86,087,493 (-)NCBI
Cytogenetic Map1q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzene  (EXP)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (EXP)
chromium(6+)  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
corosolic acid  (ISO)
Cuprizon  (EXP)
daidzein  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fumonisin B1  (ISO)
furfural  (ISO)
genistein  (ISO)
genistein 7-O-beta-D-glucoside  (ISO)
glycitein  (ISO)
glycitin  (ISO)
ivermectin  (ISO)
methyl methanesulfonate  (ISO)
nickel sulfate  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
PhIP  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sotorasib  (ISO)
thapsigargin  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
trametinib  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
undecane  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
6. Identification of hypertension-related genes through an integrated genomic-transcriptomic approach. Yagil C, etal., Circ Res. 2005 Apr 1;96(6):617-25. Epub 2005 Feb 24.
7. Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver. Yen FT, etal., J Biol Chem 1999 May 7;274(19):13390-8.
Additional References at PubMed
PMID:12477932   PMID:15265030   PMID:15489334   PMID:16396499   PMID:19199708   PMID:20458337   PMID:21245199   PMID:22671589   PMID:24889144   PMID:25753034   PMID:35463981  


Genomics

Comparative Map Data
Lsr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,313,830 - 95,329,471 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl195,313,033 - 95,329,354 (-)EnsemblGRCr8
mRatBN7.2186,185,769 - 86,201,952 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,186,431 - 86,201,952 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx191,606,550 - 91,622,061 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,072,713 - 100,088,227 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,364,848 - 93,380,361 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,383,515 - 89,399,041 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,383,519 - 89,399,041 (-)Ensemblrn6Rnor6.0
Rnor_5.0190,539,042 - 90,554,631 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4185,993,858 - 86,009,382 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera180,555,106 - 80,570,632 (-)NCBICelera
RGSC_v3.1186,071,970 - 86,087,493 (-)NCBI
Cytogenetic Map1q21NCBI
LSR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,249,002 - 35,267,964 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,248,330 - 35,267,967 (+)Ensemblhg38GRCh38
GRCh371935,739,905 - 35,758,867 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,431,399 - 40,450,707 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341940,431,398 - 40,450,705NCBI
Celera1932,452,998 - 32,472,305 (+)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,248,032 - 32,267,353 (+)NCBIHuRef
CHM1_11935,741,429 - 35,760,743 (+)NCBICHM1_1
T2T-CHM13v2.01937,793,654 - 37,812,636 (+)NCBIT2T-CHM13v2.0
Lsr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,657,195 - 30,672,894 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,657,195 - 30,672,889 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38730,957,770 - 30,973,469 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,957,770 - 30,973,464 (-)Ensemblmm10GRCm38
MGSCv37731,742,789 - 31,758,488 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36730,666,535 - 30,681,964 (-)NCBIMGSCv36mm8
Celera725,523,836 - 25,539,535 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.27NCBI
Lsr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,548,775 - 4,563,988 (+)Ensembl
ChiLan1.0NW_0049554684,548,774 - 4,563,341 (+)NCBIChiLan1.0ChiLan1.0
LSR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,261,550 - 41,280,499 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,244,926 - 43,263,857 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,195,036 - 32,214,300 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11940,932,180 - 40,951,448 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,932,180 - 40,951,448 (+)EnsemblpanPan2panpan1.1
LSR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,319,672 - 117,333,426 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,319,658 - 117,333,419 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1116,722,466 - 116,736,112 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01117,919,393 - 117,933,029 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,919,398 - 117,933,130 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,482,103 - 117,495,734 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,107,976 - 117,121,600 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,163,563 - 118,177,212 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Lsr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,607,789 - 10,621,635 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365701,023,960 - 1,038,587 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365701,023,967 - 1,038,223 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LSR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,759,073 - 44,773,379 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1644,759,091 - 44,773,378 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,183,120 - 40,192,827 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LSR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,182,899 - 30,201,850 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,183,876 - 30,201,960 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660737,957,318 - 7,975,565 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lsr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247948,271,159 - 8,285,967 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247948,271,642 - 8,286,816 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lsr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12165,066,323 - 165,082,084 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lsr
33 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:97
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000028584, ENSRNOT00000028585, ENSRNOT00000044678
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)151940904101229020Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)18126986099645535Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16540563796805205Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)158769992103769992Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat

Markers in Region
RH144092  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2186,189,287 - 86,189,508 (+)MAPPERmRatBN7.2
Rnor_6.0189,386,377 - 89,386,597NCBIRnor6.0
Rnor_5.0190,541,904 - 90,542,124UniSTSRnor5.0
RGSC_v3.4185,996,718 - 85,996,938UniSTSRGSC3.4
Celera180,557,966 - 80,558,186UniSTS
RH 3.4 Map1843.6UniSTS
Cytogenetic Map1q21UniSTS
BQ210915  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2186,191,901 - 86,192,051 (+)MAPPERmRatBN7.2
Rnor_6.0189,388,991 - 89,389,140NCBIRnor6.0
Rnor_5.0190,544,518 - 90,544,667UniSTSRnor5.0
RGSC_v3.4185,999,332 - 85,999,481UniSTSRGSC3.4
Celera180,560,580 - 80,560,729UniSTS
RH 3.4 Map1844.0UniSTS
Cytogenetic Map1q21UniSTS
UniSTS:498304  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8195,314,910 - 95,315,351 (+)Marker Load Pipeline
mRatBN7.2186,187,507 - 86,187,948 (+)MAPPERmRatBN7.2
Rnor_6.0189,384,598 - 89,385,038NCBIRnor6.0
Rnor_5.0190,540,125 - 90,540,565UniSTSRnor5.0
RGSC_v3.4185,994,939 - 85,995,379UniSTSRGSC3.4
Celera180,556,187 - 80,556,627UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 90 59 6 354 190 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000028585   ⟹   ENSRNOP00000028585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,313,033 - 95,329,354 (-)Ensembl
mRatBN7.2 Ensembl186,186,431 - 86,201,952 (-)Ensembl
Rnor_6.0 Ensembl189,383,519 - 89,399,039 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000044678   ⟹   ENSRNOP00000041379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,313,830 - 95,329,354 (-)Ensembl
mRatBN7.2 Ensembl186,186,431 - 86,201,952 (-)Ensembl
Rnor_6.0 Ensembl189,383,519 - 89,399,041 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101470   ⟹   ENSRNOP00000093545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,313,830 - 95,329,354 (-)Ensembl
mRatBN7.2 Ensembl186,186,431 - 86,201,952 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116572   ⟹   ENSRNOP00000097477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,313,834 - 95,329,354 (-)Ensembl
mRatBN7.2 Ensembl186,186,431 - 86,201,952 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000140151   ⟹   ENSRNOP00000112306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl195,313,033 - 95,329,354 (-)Ensembl
RefSeq Acc Id: NM_032616   ⟹   NP_116005
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,313,830 - 95,329,354 (-)NCBI
mRatBN7.2186,186,427 - 86,201,952 (-)NCBI
Rnor_6.0189,383,517 - 89,399,041 (-)NCBI
Rnor_5.0190,539,042 - 90,554,631 (-)NCBI
RGSC_v3.4185,993,858 - 86,009,382 (-)RGD
Celera180,555,106 - 80,570,632 (-)RGD
Sequence:
RefSeq Acc Id: XM_006228844   ⟹   XP_006228906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,313,830 - 95,329,449 (-)NCBI
mRatBN7.2186,185,769 - 86,201,952 (-)NCBI
Rnor_6.0189,383,515 - 89,399,041 (-)NCBI
Rnor_5.0190,539,042 - 90,554,631 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006228845   ⟹   XP_006228907
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,313,830 - 95,329,471 (-)NCBI
mRatBN7.2186,185,769 - 86,201,952 (-)NCBI
Rnor_6.0189,383,515 - 89,399,041 (-)NCBI
Rnor_5.0190,539,042 - 90,554,631 (-)NCBI
Sequence:
RefSeq Acc Id: NP_116005   ⟸   NM_032616
- Peptide Label: precursor
- UniProtKB: Q9WU75 (UniProtKB/Swiss-Prot),   Q497B9 (UniProtKB/Swiss-Prot),   Q9WU76 (UniProtKB/Swiss-Prot),   Q9WU74 (UniProtKB/Swiss-Prot),   A6JA42 (UniProtKB/TrEMBL),   A0A8I6GKQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006228907   ⟸   XM_006228845
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006228906   ⟸   XM_006228844
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000028585   ⟸   ENSRNOT00000028585
Ensembl Acc Id: ENSRNOP00000041379   ⟸   ENSRNOT00000044678
Ensembl Acc Id: ENSRNOP00000093545   ⟸   ENSRNOT00000101470
Ensembl Acc Id: ENSRNOP00000097477   ⟸   ENSRNOT00000116572
Ensembl Acc Id: ENSRNOP00000112306   ⟸   ENSRNOT00000140151
Protein Domains
Ig-like V-type   Immunoglobulin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9WU74-F1-model_v2 AlphaFold Q9WU74 1-593 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689946
Promoter ID:EPDNEW_R462
Type:initiation region
Name:Lsr_1
Description:lipolysis stimulated lipoprotein receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0189,399,026 - 89,399,086EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69236 AgrOrtholog
BioCyc Gene G2FUF-60053 BioCyc
Ensembl Genes ENSRNOG00000021053 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000028585 ENTREZGENE
  ENSRNOT00000028585.8 UniProtKB/Swiss-Prot
  ENSRNOT00000044678 ENTREZGENE
  ENSRNOT00000044678.6 UniProtKB/Swiss-Prot
  ENSRNOT00000116572 ENTREZGENE
  ENSRNOT00000116572.1 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7936432 IMAGE-MGC_LOAD
InterPro Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_domain-LISCH7 UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  LISCH7 UniProtKB/Swiss-Prot
KEGG Report rno:64355 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124592 IMAGE-MGC_LOAD
NCBI Gene 64355 ENTREZGENE
PANTHER LIPOLYSIS-STIMULATED LIPOPROTEIN RECEPTOR UniProtKB/Swiss-Prot
  TRANSMEMBRANE AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam LSR UniProtKB/Swiss-Prot
PhenoGen Lsr PhenoGen
RatGTEx ENSRNOG00000021053 RatGTEx
SMART SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
TIGR TC232061
  TC232062
UniProt A0A8I6GKQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0MAN1_RAT UniProtKB/TrEMBL
  A6JA40 ENTREZGENE, UniProtKB/TrEMBL
  A6JA41 ENTREZGENE, UniProtKB/TrEMBL
  A6JA42 ENTREZGENE, UniProtKB/TrEMBL
  A6JA43_RAT UniProtKB/TrEMBL
  LSR_RAT UniProtKB/Swiss-Prot
  Q497B9 ENTREZGENE
  Q9WU74 ENTREZGENE
  Q9WU75 ENTREZGENE
  Q9WU76 ENTREZGENE
UniProt Secondary Q497B9 UniProtKB/Swiss-Prot
  Q9WU75 UniProtKB/Swiss-Prot
  Q9WU76 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Lsr  lipolysis stimulated lipoprotein receptor  Lisch7  liver-specific bHLH-Zip transcription factor 7  Symbol and Name updated 1299863 APPROVED
2002-06-10 Lisch7  liver-specific bHLH-Zip transcription factor 7      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_disease identified as a possible hypertension gene 1559295
gene_expression expressed in liver 68812