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Gene: Osbpl1a (oxysterol binding protein-like 1A) Rattus norvegicus

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Symbol:

Osbpl1a

Name:

oxysterol binding protein-like 1A

RGD ID:

628888

Description:

Predicted to enable cholesterol binding activity. Predicted to be involved in lipid transport. Predicted to be located in late endosome and organelle membrane contact site. Predicted to be active in cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Orthologous to human OSBPL1A (oxysterol binding protein like 1A); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ORP-1; OSBP-related protein 1; oxysterol-binding protein-related protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	OSBPL1A (oxysterol binding protein like 1A)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther
Mus musculus (house mouse):	Osbpl1a (oxysterol binding protein-like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Osbpl1a (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	OSBPL1A (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	OSBPL1A (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Osbpl1a (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	OSBPL1A (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	OSBPL1A (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Osbpl1a (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Osbpl1a (oxysterol binding protein like 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	OSBPL1A (oxysterol binding protein like 1A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Osbpl1a (oxysterol binding protein-like 1A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	osbpl1a (oxysterol binding protein-like 1A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	osbpl1a (oxysterol binding protein-like 1A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	OSH2	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG3860	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG3860	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	obr-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	obr-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	SWH1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SWH1	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	osbpl1a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	4,178,734 - 4,383,511 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	4,179,631 - 4,369,421 (-)	Ensembl				GRCr8
mRatBN7.2	18	3,904,006 - 4,094,635 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	3,904,006 - 4,094,585 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	4,127,907 - 4,317,941 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	4,915,466 - 5,105,503 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	4,174,553 - 4,365,195 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	4,097,011 - 4,294,136 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	4,097,012 - 4,294,136 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	4,089,698 - 4,282,305 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	18	3,960,347 - 4,144,308 (-)	NCBI		Celera
Cytogenetic Map	18	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (EXP)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

buspirone (EXP)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clofibrate (ISO)

cocaine (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenthion (ISO)

fenvalerate (EXP)

fipronil (EXP)

fluoranthene (ISO)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

glyphosate (EXP)

L-methionine (ISO)

lead(0) (ISO)

levofloxacin (EXP)

methapyrilene (ISO)

methidathion (ISO)

methoxychlor (EXP)

N,N-diethyl-m-toluamide (EXP)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

nickel atom (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

pirinixic acid (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

selenium atom (ISO)

simvastatin (EXP)

tamoxifen (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

vitamin E (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cholesterol homeostasis (IEA,ISO)

lipid transport (IEA)

lysosome to ER cholesterol transport (IEA,ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IBA)

endoplasmic reticulum-endosome membrane contact site (IEA,ISO)

endosome (IEA,ISO)

late endosome (IEA,ISO,ISS)

organelle membrane contact site (IEA,ISO)

perinuclear endoplasmic reticulum (IBA)

plasma membrane (IBA)

Molecular Function

cholesterol binding (IBA,ISO)

lipid binding (IEA)

protein binding (IPI,ISO)

sterol sensor activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Structural basis of FFAT motif-mediated ER targeting.	Kaiser SE, etal., Structure. 2005 Jul;13(7):1035-45.
4.	Androgen-regulated expression of a novel member of the aldo-keto reductase superfamily in regrowing rat prostate.	Nishi N, etal., Endocrinology 2000 Sep;141(9):3194-9.
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.	Xu Y, etal., J Biol Chem 2001 May 25;276(21):18407-14.

Additional References at PubMed

PMID:16176980	PMID:17428193	PMID:19056867

Genomics

Comparative Map Data

Osbpl1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	4,178,734 - 4,383,511 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	4,179,631 - 4,369,421 (-)	Ensembl				GRCr8
mRatBN7.2	18	3,904,006 - 4,094,635 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	3,904,006 - 4,094,585 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	4,127,907 - 4,317,941 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	4,915,466 - 5,105,503 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	4,174,553 - 4,365,195 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	4,097,011 - 4,294,136 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	4,097,012 - 4,294,136 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	4,089,698 - 4,282,305 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	18	3,960,347 - 4,144,308 (-)	NCBI		Celera
Cytogenetic Map	18	p13	NCBI

OSBPL1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	24,162,045 - 24,397,824 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	24,162,045 - 24,397,880 (-)	Ensembl			hg38	GRCh38
GRCh37	18	21,742,009 - 21,977,788 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	19,996,007 - 20,231,788 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	18	19,996,010 - 20,231,788	NCBI
Celera	18	18,558,319 - 18,792,861 (-)	NCBI		Celera
Cytogenetic Map	18	q11.2	NCBI
HuRef	18	18,598,065 - 18,833,825 (-)	NCBI		HuRef
CHM1_1	18	21,669,277 - 21,904,868 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	24,356,384 - 24,592,191 (-)	NCBI		T2T-CHM13v2.0

Osbpl1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	12,886,955 - 13,074,933 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	12,888,371 - 13,074,898 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	12,753,898 - 12,941,871 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	12,755,314 - 12,941,841 (-)	Ensembl			mm10	GRCm38
MGSCv37	18	12,914,537 - 13,100,229 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	12,899,197 - 13,084,889 (-)	NCBI		MGSCv36	mm8
Celera	18	12,987,816 - 13,172,462 (-)	NCBI		Celera
Cytogenetic Map	18	A1	NCBI
cM Map	18	6.78	NCBI

Osbpl1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	12,530,135 - 12,718,703 (-)	Ensembl
ChiLan1.0	NW_004955402	12,530,130 - 12,718,703 (-)	NCBI	ChiLan1.0	ChiLan1.0

OSBPL1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	41,594,237 - 41,857,937 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	27,286,833 - 27,550,335 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	17,414,824 - 17,669,178 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	21,037,587 - 21,270,216 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	21,037,586 - 21,270,216 (-)	Ensembl			panPan2	panpan1.1

OSBPL1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	63,995,570 - 64,223,213 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	63,995,184 - 64,222,157 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	63,444,473 - 63,672,084 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	64,054,333 - 64,281,774 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	64,054,357 - 64,281,762 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	63,724,290 - 63,951,485 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	63,738,846 - 63,966,751 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	64,043,599 - 64,271,300 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Osbpl1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	60,070,367 - 60,269,932 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936550	3,544,419 - 3,746,059 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936550	3,545,941 - 3,745,716 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OSBPL1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	108,997,735 - 109,221,010 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	108,997,730 - 109,241,950 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	101,663,953 - 101,813,634 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OSBPL1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	56,122,942 - 56,370,730 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	56,144,766 - 56,369,599 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	30,889,832 - 31,120,382 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Osbpl1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	7,864,036 - 8,054,881 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624770	7,855,776 - 8,054,886 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Osbpl1a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	30,762,551 - 30,949,460 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Osbpl1a
1615 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	21
Count of miRNA genes:	21
Interacting mature miRNAs:	21
Transcripts:	ENSRNOT00000072478
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	26032889	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	44930869	Rat
1641910	Colcr3	Colorectal carcinoma resistance QTL 3	5.02	0.000007	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	1	25022372	Rat
1331781	Scl28	Serum cholesterol level QTL 28	3.995		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	1	25071266	Rat
6903356	Bp354	Blood pressure QTL 354	4.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	15642423	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	3811902	30809809	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34566578	Rat
6903345	Bp349	Blood pressure QTL 349	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	26032889	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	1	31610627	Rat
6903349	Bp351	Blood pressure QTL 351	3.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	54490981	Rat
6903351	Bp352	Blood pressure QTL 352	3.3		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	3917226	48917226	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34566578	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	4307354	49307354	Rat

Markers in Region

RH134647

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	3,905,580 - 3,906,784 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	4,097,677 - 4,098,880	NCBI	Rnor6.0
Rnor_5.0	18	4,090,364 - 4,091,567	UniSTS	Rnor5.0
Celera	18	3,961,013 - 3,962,216	UniSTS
RH 3.4 Map	18	83.01	UniSTS

RH141432

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	3,906,129 - 3,906,318 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	4,098,226 - 4,098,414	NCBI	Rnor6.0
Rnor_5.0	18	4,090,913 - 4,091,101	UniSTS	Rnor5.0
Celera	18	3,961,562 - 3,961,750	UniSTS

RH141518

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	3,913,347 - 3,913,567 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	4,105,448 - 4,105,667	NCBI	Rnor6.0
Rnor_5.0	18	4,098,135 - 4,098,354	UniSTS	Rnor5.0
Celera	18	3,968,784 - 3,969,003	UniSTS
RH 3.4 Map	18	81.11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_172023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096597	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096598	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277125	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277129	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010059548	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010059549	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB089316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228055	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000091909 ⟹ ENSRNOP00000072477

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	4,179,631 - 4,369,270 (-)	Ensembl
mRatBN7.2 Ensembl	18	3,904,006 - 4,094,585 (-)	Ensembl
Rnor_6.0 Ensembl	18	4,097,012 - 4,294,136 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119742 ⟹ ENSRNOP00000087195

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	4,179,644 - 4,278,013 (-)	Ensembl
mRatBN7.2 Ensembl	18	3,904,916 - 4,003,290 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000162073 ⟹ ENSRNOP00000109377

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	4,179,644 - 4,369,421 (-)	Ensembl

RefSeq Acc Id:

NM_172023 ⟹ NP_742020

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,179,643 - 4,369,270 (-)	NCBI
mRatBN7.2	18	3,904,915 - 4,094,555 (-)	NCBI
Rnor_6.0	18	4,097,011 - 4,294,136 (-)	NCBI
Rnor_5.0	18	4,089,698 - 4,282,305 (-)	NCBI
Celera	18	3,960,347 - 4,144,308 (-)	RGD

Sequence:

show sequence

GGGATCCTGGACCGTCCTCGTGAGAGTGGCCCTCGTGGGTGACCGGCGTCCAGTGGGCGCGGCC
CGGCCTGTGGTGGAGGCCGCCTCAGGAGCGGGACCCGCAATCCCGCAGGCCCAGCTGTGAGCAC
GTTATGCTGCTGGGTGAGAGCTCCACTTCTGTTTTTCAGTCCAGAAATGAACACAGAAGCCGAG
CAGCAGCTTCTCCATCACGCCAGGAATGGCAATGCTGAAGAAGTGAGGAAGCTGCTGGAAGCCA
TGGCGCGGGCTGAAGTGGTCGCTGACATTGACTGTAAAGGAAGAAGTAAGTCTAACTTGGGCTG
GACACCTCTTCATCTGGCATGCTATTTTGGACACAAACAAGTGGTCCAGGATCTGTTGAAGGCT
GGTGCCAAAGTGAACATGTTAAATGACATGGGGGACACGCCGCTGCACCGAGCTGCCTTCACAG
GACGAAAGGAGCTAGTAATGCTTCTTTTAGAATATAATGCTGACACTACTGTCGTAAATGGAAG
TGGACAGACAGCAAAAGAAGCCACCCATGACAAAGAAATCAGACAAATGCTTGAAGCTGTGGAA
AGGACTCAACAAAGAAAGCTTGAAGAATTGCTTCTAGGAGCAGCTAGAGAAGGAAGAACAGCTG
AAGTGTCAGCTCTGCTCAGCAGGCCCAATCCTCCTGATGTGAACTGCTCAGATCAGTTAGGAAA
TACTCCCTTGCACTGTGCAGCCTACCGGGCCCACAAGCAGTGTGTCTTAAAGCTTCTGAGAAGT
GGAGCTGACCCCAGCCTGAAGAACAAGAACGATCAGAAACCTCTTGACCTTGCCCATGGCACTG
AAATGAAACATATCCTTGTTGGTAATAAGGTTGTCCACAAAGCCCTGAAACGCTTTGAAGGCCC
TCTCTGGAAGAGTTCAAGATTTTTTGGCTGGAAGTTATTCTGGGTAGTGTTAGAACACGGCGTC
CTTTCCTGGTACAGGAAGCAGCCTGATGCAGTCCATAATTCTTACCGCCAAGGATGCAAACACC
TGACTCAAGCGGTGTGCACGGTGAAACCTACAGATGGCTGCCTCTTCTCTGTCCGATGCTTTGA
TGACACCGTTCATGGCTTTCGGGTTCCTAAGAACAGCCTACAGCAATCGAGAGAGAAGTGGCTG
GAAGCAATTGAAGAACATTCTGCATACAGCACTCACTACTGCTCCCAGGATCAGGTGACTGATG
ATGAAGAGGAAGATGTAGCTTCTGCCATGGACCTGAAGGAGTCCTTAGCGAGAGCACAAACATG
TCAACAGAGACTAGATAGGGAAATTTACAACTTTCTCAAAATGATTAAGGAGTGCGATGTGGCC
AAAGATATGCTTCCATCATTTCTTCAGAAAGCTGACGTGCTCTCCGAAGCTTCTAGAGAGACTT
GTGTGGCGCTGAGTGACTGTCTTAATCTCTTCACTAAACAGGAAGGGGTAAGGAATTTTAAATT
GGAACAGGAGCAAGAAAAAAACAAAATTTTGTCAGAAGCGCTGGAGACTTTAGCCACTGAGCAT
CATGAACTAGAACGATCCCTGGTTGAAGGATCTCCGCCTGTCAGCATCCTTAGTGAGGACGAGT
TCTATGATGCACTGTCAGGGTCCGAGTCCGAGGGGTCGCTGACTTGTCTGGAAGCTGTGACAGC
ACGCGCCTTTGAAGAGAACGAAGTGCCTGCGAACAGCGGGAAGCACAGAATGTCCGAAGGGAAG
GACTGTGGCGGAGGAGATGCGCTCTCCAACGGCATTAAAAAGCACAGAACAAGCCTGCCATCAC
CCATGTTCTCCAGAAATGACTTCAGCATCTGGAGCATCCTCAGGAAATGCATTGGGATGGAACT
GTCCAAGATCACAATGCCAGTCATCTTTAATGAGCCTCTGAGCTTTCTGCAGCGGCTGACTGAG
TACATGGAGCACACTTACCTCATCCACAAAGCCAGCTCATTCTCTGATCCTGTGGAAAGGATGC
AGTGTGTGGCTGCATTTGCTGTGTCTGCCGTTGCTTCTCAGTGGGAGCGCACTGGGAAACCCTT
CAACCCACTTCTGGGAGAGACTTACGAATTAGTTCGAGATGACCTTGGATTTAGGCTCATCTCA
GAGCAGGTCAGCCACCACCCCCCCATCAGTGCATTCCATGCAGAAGGACTCAACAACGATTTCA
TCTTCCATGGCTCAATTTACCCCAAGCTGAAGTTCTGGGGCAAGAGTGTAGAAGCAGAACCTAA
AGGGACCATCACCTTGGAGCTTTTAGAACACAACGAAGCATACACATGGACAAACCCCACCTGC
TGTGTGCATAACATCATCGTGGGCAAACTCTGGATCGAACAGTATGGCAATGTGGAAATCATAA
ACCACAAGACTGGGGACAAGTGTGTGTTGAATTTTAAGCCATGTGGTCTTTTTGGCAAGGAATT
ACACAAAGTTGAAGGCTACATACAAGATAAAAGCAAAAAGAAACTCTGTGCTCTCTACGGGAAG
TGGACCGAGTGCTTGTACAGTGTAGACCCTGCCACTTTTGACGCTTACAAAAAAAACGATAAGA
AAAACACAGAAGAGAAGAAGACCAGCAAACAGGCAAGCACATCTGAGGAGTCTGACGAAATGCC
AGTGCCGGACTCTGAGAGCGTATTTGTTATTCCTGGCAGTGCGCTCCTGTGGCGGATAGCCCCG
CGGCCTCCCAACTCTGCTCAGATGTATAATTTTACCAGCTTTGCCATGGTCTTGAATGAGGTAG
ACAAGGAGATGGAGACCGTGATTCCCAAGACTGACTGCAGGCTGCGGCCTGACATCAGAGCCAT
GGAGAACGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAACGACTCGAGGAAAAACAAAGAGCA
GCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACAAGGTGGTTTCATCAAGGCCCTA
ACCCCTACAGTGGAGCACAGGACTGGATTTATTCTGGCAGCTACTGGGACAGAAACTACTTCAA
TTTGCCTGATATTTATTAAAGTGCAGAGAAGTCCAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039096596 ⟹ XP_038952524

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,369,342 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,094,635 (-)	NCBI

RefSeq Acc Id:

XM_039096597 ⟹ XP_038952525

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,369,360 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,094,635 (-)	NCBI

RefSeq Acc Id:

XM_039096598 ⟹ XP_038952526

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,360,531 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,085,815 (-)	NCBI

RefSeq Acc Id:

XM_039096601 ⟹ XP_038952529

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,313,836 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,039,113 (-)	NCBI

RefSeq Acc Id:

XM_039096602 ⟹ XP_038952530

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,316,996 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,042,276 (-)	NCBI

RefSeq Acc Id:

XM_039096603 ⟹ XP_038952531

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,313,833 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,039,109 (-)	NCBI

RefSeq Acc Id:

XM_039096605 ⟹ XP_038952533

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,287,116 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,012,387 (-)	NCBI

RefSeq Acc Id:

XM_039096606 ⟹ XP_038952534

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,287,122 (-)	NCBI
mRatBN7.2	18	3,904,006 - 4,012,382 (-)	NCBI

RefSeq Acc Id:

XM_063277125 ⟹ XP_063133195

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,383,511 (-)	NCBI

RefSeq Acc Id:

XM_063277126 ⟹ XP_063133196

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,383,498 (-)	NCBI

RefSeq Acc Id:

XM_063277127 ⟹ XP_063133197

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,383,501 (-)	NCBI

RefSeq Acc Id:

XM_063277128 ⟹ XP_063133198

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,369,360 (-)	NCBI

RefSeq Acc Id:

XM_063277129 ⟹ XP_063133199

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,360,458 (-)	NCBI

RefSeq Acc Id:

XM_063277130 ⟹ XP_063133200

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,313,837 (-)	NCBI

RefSeq Acc Id:

XM_063277131 ⟹ XP_063133201

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,313,782 (-)	NCBI

RefSeq Acc Id:

XM_063277132 ⟹ XP_063133202

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,313,817 (-)	NCBI

RefSeq Acc Id:

XM_063277133 ⟹ XP_063133203

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,178,734 - 4,265,957 (-)	NCBI

RefSeq Acc Id:

XR_010059548

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,191,426 - 4,360,531 (-)	NCBI

RefSeq Acc Id:

XR_010059549

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	4,265,925 - 4,361,523 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_742020	(Get FASTA)	NCBI Sequence Viewer
	XP_038952524	(Get FASTA)	NCBI Sequence Viewer
	XP_038952525	(Get FASTA)	NCBI Sequence Viewer
	XP_038952526	(Get FASTA)	NCBI Sequence Viewer
	XP_038952529	(Get FASTA)	NCBI Sequence Viewer
	XP_038952530	(Get FASTA)	NCBI Sequence Viewer
	XP_038952531	(Get FASTA)	NCBI Sequence Viewer
	XP_038952533	(Get FASTA)	NCBI Sequence Viewer
	XP_038952534	(Get FASTA)	NCBI Sequence Viewer
	XP_063133195	(Get FASTA)	NCBI Sequence Viewer
	XP_063133196	(Get FASTA)	NCBI Sequence Viewer
	XP_063133197	(Get FASTA)	NCBI Sequence Viewer
	XP_063133198	(Get FASTA)	NCBI Sequence Viewer
	XP_063133199	(Get FASTA)	NCBI Sequence Viewer
	XP_063133200	(Get FASTA)	NCBI Sequence Viewer
	XP_063133201	(Get FASTA)	NCBI Sequence Viewer
	XP_063133202	(Get FASTA)	NCBI Sequence Viewer
	XP_063133203	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAC07227	(Get FASTA)	NCBI Sequence Viewer
	EDL75019	(Get FASTA)	NCBI Sequence Viewer
	EDL75020	(Get FASTA)	NCBI Sequence Viewer
	EDL75021	(Get FASTA)	NCBI Sequence Viewer
	EDL75022	(Get FASTA)	NCBI Sequence Viewer
	EDL75023	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072477
	ENSRNOP00000087195
	ENSRNOP00000109377
GenBank Protein	Q8K4M9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_742020 ⟸ NM_172023

- UniProtKB:

Q8K4M9 (UniProtKB/Swiss-Prot), A0A0G2K327 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNTEAEQQLLHHARNGNAEEVRKLLEAMARAEVVADIDCKGRSKSNLGWTPLHLACYFGHKQVV
QDLLKAGAKVNMLNDMGDTPLHRAAFTGRKELVMLLLEYNADTTVVNGSGQTAKEATHDKEIRQ
MLEAVERTQQRKLEELLLGAAREGRTAEVSALLSRPNPPDVNCSDQLGNTPLHCAAYRAHKQCV
LKLLRSGADPSLKNKNDQKPLDLAHGTEMKHILVGNKVVHKALKRFEGPLWKSSRFFGWKLFWV
VLEHGVLSWYRKQPDAVHNSYRQGCKHLTQAVCTVKPTDGCLFSVRCFDDTVHGFRVPKNSLQQ
SREKWLEAIEEHSAYSTHYCSQDQVTDDEEEDVASAMDLKESLARAQTCQQRLDREIYNFLKMI
KECDVAKDMLPSFLQKADVLSEASRETCVALSDCLNLFTKQEGVRNFKLEQEQEKNKILSEALE
TLATEHHELERSLVEGSPPVSILSEDEFYDALSGSESEGSLTCLEAVTARAFEENEVPANSGKH
RMSEGKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSF
LQRLTEYMEHTYLIHKASSFSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDL
GFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYT
WTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKL
CALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKTSKQASTSEESDEMPVPDSESVFVIPGSAL
LWRIAPRPPNSAQMYNFTSFAMVLNEVDKEMETVIPKTDCRLRPDIRAMENGEIDQASEEKKRL
EEKQRAARKNRSKSEEDWKTRWFHQGPNPYSGAQDWIYSGSYWDRNYFNLPDIY

hide sequence

Ensembl Acc Id:

ENSRNOP00000072477 ⟸ ENSRNOT00000091909

RefSeq Acc Id:	XP_038952525 ⟸ XM_039096597
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952524 ⟸ XM_039096596
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952526 ⟸ XM_039096598
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952530 ⟸ XM_039096602
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I6GFS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952529 ⟸ XM_039096601
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6GFS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952531 ⟸ XM_039096603
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I6GFS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952533 ⟸ XM_039096605
- Peptide Label:	isoform X9
- UniProtKB:	A6KLS6 (UniProtKB/TrEMBL), A0A8I6GFS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952534 ⟸ XM_039096606
- Peptide Label:	isoform X9
- UniProtKB:	A6KLS6 (UniProtKB/TrEMBL), A0A8I6GFS2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000087195 ⟸ ENSRNOT00000119742

RefSeq Acc Id:	XP_063133195 ⟸ XM_063277125
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133197 ⟸ XM_063277127
- Peptide Label:	isoform X2
- UniProtKB:	A6KLS5 (UniProtKB/TrEMBL), A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133196 ⟸ XM_063277126
- Peptide Label:	isoform X2
- UniProtKB:	A6KLS5 (UniProtKB/TrEMBL), A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133198 ⟸ XM_063277128
- Peptide Label:	isoform X2
- UniProtKB:	A6KLS5 (UniProtKB/TrEMBL), A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133199 ⟸ XM_063277129
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2K327 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133200 ⟸ XM_063277130
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6GFS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133202 ⟸ XM_063277132
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6GFS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133201 ⟸ XM_063277131
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6GFS2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133203 ⟸ XM_063277133
- Peptide Label:	isoform X10
- UniProtKB:	A6KLS7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000109377 ⟸ ENSRNOT00000162073

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8K4M9-F1-model_v2	AlphaFold	Q8K4M9	1-950	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700642

Promoter ID:

EPDNEW_R11165

Type:

single initiation site

Name:

Osbpl1a_1

Description:

oxysterol binding protein-like 1A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	4,294,114 - 4,294,174	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628888	AgrOrtholog
BioCyc Gene	G2FUF-8352	BioCyc
Ensembl Genes	ENSRNOG00000054058	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000091909	ENTREZGENE
	ENSRNOT00000119742	ENTREZGENE
	ENSRNOT00000162073	ENTREZGENE
Gene3D-CATH	1.25.40.20	UniProtKB/Swiss-Prot
	2.30.29.30	UniProtKB/Swiss-Prot
	2.40.160.120	UniProtKB/Swiss-Prot
	3.30.70.3490	UniProtKB/Swiss-Prot
InterPro	Ankyrin_rpt	UniProtKB/Swiss-Prot
	Ankyrin_rpt-contain_sf	UniProtKB/Swiss-Prot
	OSBP_sf	UniProtKB/Swiss-Prot
	Oxysterol-bd	UniProtKB/Swiss-Prot
	Oxysterol-bd_CS	UniProtKB/Swiss-Prot
	PH-like_dom_sf	UniProtKB/Swiss-Prot
	PH_domain	UniProtKB/Swiss-Prot
KEGG Report	rno:259221	UniProtKB/Swiss-Prot
NCBI Gene	259221	ENTREZGENE
PANTHER	OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 1	UniProtKB/Swiss-Prot
	PTHR10972	UniProtKB/Swiss-Prot
Pfam	Ank_2	UniProtKB/Swiss-Prot
	Oxysterol_BP	UniProtKB/Swiss-Prot
PhenoGen	Osbpl1a	PhenoGen
PRINTS	ANKYRIN	UniProtKB/Swiss-Prot
PROSITE	ANK_REP_REGION	UniProtKB/Swiss-Prot
	ANK_REPEAT	UniProtKB/Swiss-Prot
	OSBP	UniProtKB/Swiss-Prot
	PH_DOMAIN	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000054058	RatGTEx
SMART	ANK	UniProtKB/Swiss-Prot
	SM00233	UniProtKB/Swiss-Prot
Superfamily-SCOP	PH domain-like	UniProtKB/Swiss-Prot
	SSF144000	UniProtKB/Swiss-Prot
	SSF48403	UniProtKB/Swiss-Prot
UniProt	A0A0G2K327	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GFS2	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LF09_RAT	UniProtKB/TrEMBL
	A6KLS5	ENTREZGENE, UniProtKB/TrEMBL
	A6KLS6	ENTREZGENE, UniProtKB/TrEMBL
	A6KLS7	ENTREZGENE, UniProtKB/TrEMBL
	A6KLS8_RAT	UniProtKB/TrEMBL
	OSBL1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-01-20	Osbpl1a	oxysterol binding protein-like 1A			Symbol and Name status set to approved	1299863	APPROVED
2003-02-27	Osbpl1a	oxysterol binding protein-like 1A			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in various adult rat tissues and also the ventral and dorsolateral prostates	631985
gene_process	may be involved in growth-related processes in the prostate	631985

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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