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Gene: Stab2 (stabilin 2) Rattus norvegicus

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Symbol:

Stab2

Name:

stabilin 2

RGD ID:

628822

Description:

Enables hyaluronic acid binding activity. Involved in endocytosis. Located in external side of plasma membrane. Orthologous to human STAB2 (stabilin 2); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL-2; Hare; hyaluronan receptor for endocytosis; LOC299701; RGD1560941; similar to stabilin-2; stabilin-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	STAB2 (stabilin 2)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Stab2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Stab2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	STAB2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	STAB2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Stab2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	STAB2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	STAB2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Stab2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Stab2 (stabilin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	STAB2 (stabilin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Stab2 (stabilin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	stab2 (stabilin 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	stab2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	stab2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	23,136,938 - 23,342,633 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	23,136,941 - 23,320,562 (-)	Ensembl				GRCr8
mRatBN7.2	7	21,249,426 - 21,433,051 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	21,249,391 - 21,434,042 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	23,223,948 - 23,405,067 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	25,386,660 - 25,567,761 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	25,163,729 - 25,344,850 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	27,369,853 - 27,552,078 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	27,369,853 - 27,552,078 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	27,488,874 - 27,666,514 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	23,470,117 - 23,497,983 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	18,430,372 - 18,608,299 (-)	NCBI		Celera
RGSC_v3.1	7	23,490,342 - 23,518,256 (-)	NCBI
Cytogenetic Map	7	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hepatocellular carcinoma (ISO)

Prostatic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (EXP)

17beta-estradiol (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-palmitoylglycerol (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

allethrin (EXP)

alpha-Zearalanol (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP)

cadmium atom (EXP)

cadmium dichloride (EXP)

cantharidin (ISO)

Cuprizon (EXP)

cyhalothrin (EXP)

cypermethrin (EXP)

dibenz[a,h]anthracene (ISO)

dioxygen (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenthion (ISO)

fenvalerate (EXP)

glafenine (EXP)

hydralazine (ISO)

mono(2-ethylhexyl) phthalate (ISO)

oxaliplatin (EXP)

paracetamol (ISO)

PCB138 (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

pyrethrins (EXP)

resveratrol (ISO)

sodium arsenate (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

triclosan (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell adhesion (IEA)

defense response to bacterium (IEA,ISO)

defense response to Gram-positive bacterium (IEA,ISO,ISS)

endocytosis (IDA,IEA)

hyaluronan catabolic process (IEA,ISO)

receptor-mediated endocytosis (IEA,ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISO)

external side of plasma membrane (IDA)

membrane (IEA)

plasma membrane (IEA,ISO)

Molecular Function

calcium ion binding (IEA)

cargo receptor activity (IEA,ISO)

hyaluronic acid binding (IDA,IEA)

low-density lipoprotein particle binding (IEA,ISO)

low-density lipoprotein particle receptor activity (IEA,ISO)

protein binding (ISO)

scavenger receptor activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Molecular Cloning and Functional Expression of the Rat 175-kDa Hyaluronan Receptor for Endocytosis.	Zhou B, etal., Mol Biol Cell 2002 Aug;13(8):2853-68.

Additional References at PubMed

PMID:11829752	PMID:12077138	PMID:12645574	PMID:12933790	PMID:15208308	PMID:15572036	PMID:19359419	PMID:21810271	PMID:23530033	PMID:25253654

Genomics

Comparative Map Data

Stab2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	23,136,938 - 23,342,633 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	23,136,941 - 23,320,562 (-)	Ensembl				GRCr8
mRatBN7.2	7	21,249,426 - 21,433,051 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	21,249,391 - 21,434,042 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	23,223,948 - 23,405,067 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	25,386,660 - 25,567,761 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	25,163,729 - 25,344,850 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	27,369,853 - 27,552,078 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	27,369,853 - 27,552,078 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	27,488,874 - 27,666,514 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	23,470,117 - 23,497,983 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	18,430,372 - 18,608,299 (-)	NCBI		Celera
RGSC_v3.1	7	23,490,342 - 23,518,256 (-)	NCBI
Cytogenetic Map	7	q13	NCBI

STAB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	103,587,273 - 103,766,719 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	103,587,273 - 103,766,719 (+)	Ensembl			hg38	GRCh38
GRCh37	12	103,981,051 - 104,160,497 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	102,505,199 - 102,684,632 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	12	102,483,535 - 102,662,967	NCBI
Celera	12	103,644,967 - 103,824,194 (+)	NCBI		Celera
Cytogenetic Map	12	q23.3	NCBI
HuRef	12	101,040,941 - 101,220,117 (+)	NCBI		HuRef
CHM1_1	12	103,947,453 - 104,126,824 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	103,548,545 - 103,728,010 (+)	NCBI		T2T-CHM13v2.0

Stab2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	86,677,058 - 86,843,902 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	86,677,062 - 86,843,889 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	86,841,194 - 87,008,038 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	86,841,198 - 87,008,025 (-)	Ensembl			mm10	GRCm38
MGSCv37	10	86,303,955 - 86,470,687 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	86,271,007 - 86,437,741 (-)	NCBI		MGSCv36	mm8
Celera	10	88,822,759 - 88,979,326 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	43.14	NCBI

Stab2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	38,393,650 - 38,533,815 (+)	Ensembl
ChiLan1.0	NW_004955405	38,393,636 - 38,533,701 (+)	NCBI	ChiLan1.0	ChiLan1.0

STAB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	111,733,831 - 111,829,524 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	111,648,668 - 111,825,921 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	101,165,854 - 101,343,144 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	104,561,264 - 104,738,599 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	104,561,264 - 104,738,599 (+)	Ensembl			panPan2	panpan1.1

STAB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	42,187,074 - 42,328,874 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	42,187,790 - 42,328,883 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	42,558,264 - 42,698,952 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	42,846,797 - 42,986,317 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	42,846,735 - 42,986,317 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	42,113,980 - 42,253,105 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	42,212,117 - 42,351,533 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	42,481,549 - 42,622,125 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Stab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	17,667,645 - 17,820,561 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	10,678,115 - 10,833,963 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	10,678,074 - 10,817,870 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STAB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	5	80,692,459 - 80,863,221 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	84,332,946 - 84,425,221 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

STAB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	98,780,148 - 98,953,871 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	98,779,921 - 98,954,913 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666037	146,038,165 - 146,206,183 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Stab2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624750	4,866,792 - 5,016,335 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624750	4,866,438 - 5,016,958 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Stab2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	1	165,955,547 - 166,134,795 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Stab2
1750 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	31
Count of miRNA genes:	29
Interacting mature miRNAs:	29
Transcripts:	ENSRNOT00000059538
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354644	Spl4	Serum phospholipid level QTL 4	4.9		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	7	21541977	51639954	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	1	23748937	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	7216097	52216097	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	10517086	62346019	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1709527	46709527	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	10112916	60150541	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	9460877	54460877	Rat
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	29716167	Rat
1354637	Scl30	Serum cholesterol level QTL 30	3.7		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	7	21541977	51639954	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34650782	Rat
1354639	Spl5	Serum phospholipid level QTL 5	3.9		blood LDL phospholipid amount (VT:0010505)	blood low density lipoprotein phospholipid level (CMO:0001568)	7	21541977	35707405	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	32612984	Rat
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1669658	46669658	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	10112916	99900612	Rat
2290372	Gluco33	Glucose level QTL 33	2.71		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	1	31777942	Rat
1300149	Cm6	Cardiac mass QTL 6	4.09		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	7	1	104117804	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	32612984	Rat
1582260	Bw72	Body weight QTL 72	3.2	0.0043	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582261	Bw69	Body weight QTL 69	3.2	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1582262	Bw75	Body weight QTL 75	3	0.0038	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	39960528	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	21541977	86817926	Rat
1300138	Hrtrt9	Heart rate QTL 9	4.72		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	10498820	55498820	Rat
61369	Mcs2	Mammary carcinoma susceptibility QTL 2	3.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	20920494	37412865	Rat
738033	Anxrr6	Anxiety related response QTL 6	4.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	7	17460447	62460447	Rat
70207	Niddm31	Non-insulin dependent diabetes mellitus QTL 31	3.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	20057232	65057232	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
10	9	49	160	91	88	59	55	59	6	281	134	11	132	70	78	29	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001246357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY007370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GQ477370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000059538 ⟹ ENSRNOP00000056294

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	23,136,941 - 23,320,562 (-)	Ensembl
mRatBN7.2 Ensembl	7	21,249,391 - 21,434,042 (-)	Ensembl
Rnor_6.0 Ensembl	7	27,369,853 - 27,552,078 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099162 ⟹ ENSRNOP00000091563

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	23,136,951 - 23,320,562 (-)	Ensembl
mRatBN7.2 Ensembl	7	21,250,313 - 21,434,042 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112055 ⟹ ENSRNOP00000078245

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	23,136,951 - 23,320,562 (-)	Ensembl
mRatBN7.2 Ensembl	7	21,249,391 - 21,434,042 (-)	Ensembl

RefSeq Acc Id:

NM_001246357 ⟹ NP_001233286

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	23,136,951 - 23,320,562 (-)	NCBI
mRatBN7.2	7	21,249,426 - 21,433,051 (-)	NCBI
Rnor_6.0	7	27,369,853 - 27,552,078 (-)	NCBI
Rnor_5.0	7	27,488,874 - 27,666,514 (-)	NCBI
Celera	7	18,430,372 - 18,608,299 (-)	NCBI

Sequence:

show sequence

ATGGGAAGGAGCAAGCTTTTCCTCAGCATGCTGCTGCCTTTAATTCCTCTCTTCCTGGGGCTGG
TTGTGCAAAATGCCTGCTCCCCAACTGAAGGCCCAGAACTGGCAAAAAGATGTGATAAGAAGTC
TACTCTAACCATCAAGACGGAGTGCCAATCCTGCTCAGCTAACTTTGCAGTCAAGTGTCCAGAT
GGCTACATCAAGGTTACCAGTGGCTCTGCTGGGGTTCGAGATTGCAGGTATTCGCTTGACATCC
AGTCATACGTTCTGGCCATCCCTGGATGCCGCCATATCTGTAGGAAGGATTATCTACAACCTCA
ATGTTGTCCAGGACACTGGGGCCCAGACTGCATGGAGTGCCCAGGAGGAGCAAGGGCACCATGC
GGTGGCAGGGGCGTTTGTGACGAAGGCATGGAAGGGACTGGAAGCTGCTCCTGCCAAGCAGGCT
TCAGTGGAACAGCCTGTGAAGCCTGTGCTACTGACAACGTTTTTGGGCCCAACTGTTCAGCAGT
CTGCAGCTGTGTCCACGGTGTGTGCAACAGCGGGCTCAACGGTGACGGAACCTGTGAGTGCTTG
TCTGCATACAGGGGTCCCAAGTGCGACAAGCCCATCCCGGAGTGTGCAACCTTGCTCTGCCCAG
AAAACTCCAGATGTTCACCTTCCAGCAAAGATGAAACTAAACTTCAGTGCAAATGCCTTCCCAA
TTACGAAGGGGACGGCCATAACTGCAAGCCCATCAACCCATGTTTAAAAACCATCTGCCACCCT
CACGCAAGTTGTTCCTACCTGGGACCAAATCGGCACAGTTGCATATGCCAAAAAGGCTACCAAG
GAGATGGTCAAGTGTGTCTGCCAGTGGACCCCTGCCAAACGAACTATGGAAAGTGCCCTCCAGA
GTCTACAGTGTGCAAATACGACGGGCCTGGACAGTCCCACTGCGAGTGTAAAGAACATTACCGC
AATTTTGTACCTGGAGTGGGGTGCAGTATGACGGATATCTGTGAATCGAACAACCCATGTCATA
AGAATGCAAACTGCAGCACAGTCTCACCAGGCAAAACCAAATGCACTTGCCAGAAAGGTTATGT
GGGCGATGGCCTGAACTGCTATGGAAACATCATGCAGAGACTCAGAGAATTAAATACTGAACCC
AGAGGGATGTGGCAAGGACAGCTGACCTCTTTCATCTCCATCCTGGACAGGACTTATGCCTGGC
CGCTGAGCAACCTGGGACCCTTCACTGTGCTGCTGCCCTCAGACAAGGGGCTAAAAGGGGTTGA
TGTAAAGGAGCTCTTGATGGACAAAGAGGCTGCTCGGTACTTCGCGAAGCTCCACATCATTGCT
GGGCAAATGAGCATGGAGCAGATGTATCACTTGGACACCTTCTACACCTTGACGGGAAAGTCAG
GGGAAATCTTCAACAAAGATAAGGACAATCAACTAAAGCTCAAACTTCATGGAAGCAAAGTAGT
GAAAATTATCCAGGGGAACATCGTTGCTTCAAATGGGCTTGTGCATATCCTGGACAGAGCCATG
GACAAGACAGAACCCACATTTGCAAGCAACCCCCAGCAAACCATCATGGCGATGCTACAACCAA
GATATGGCAGGTTCAGATCTTTGCTAGAGAAAACCAATGTTGGACAAATCCTAGATGAAGGTGG
ACCATACACCATTTTTGTTCCAAGTAATGAAGCATTGAGCAACATGAAGGCTGACATCTTGGAC
TACCTCCTTTCTCCAGAGGGCTCTCGGAAACTTCTGGAACTCGTCAGATACCACATTGTTGCGT
TTACTCAGCTGGAAGTAGCCACTCTGGTCTCGACGCCTCACATCAGGAGCATGGCCAACCAGAT
CATCAAGTTTAACATAACCAGCAAAGGGCAGATTCTGGCAAACAACGTGGCCATGGATGAAACC
GAAGTCGCTGCCAAAAATGGCCGAATTTACACACTGACGGGAGTCCTCATTCCTCCCTCCATCC
TCCCGATTCTTCCCCACCGATGCAATGAAACAAAGATCGAGCTGAAACTGGGCACTTGCGTGAG
CTGTTCCACGAAACACTGGAGCAAATGCCCTGCTGACTCAAAGCCCGCGACAATCTTCTCGTCC
TGTTTCTACAGCAGCAGAGTACGGAACCTGAAAAGTGGCTGTGCCCGATATTGTAATGTGACTG
TGGAGATACCCAGATGCTGCAAAGGTTTCTTTGGGCCCGACTGCACCCCATGTCCAGGAGGCTT
CTTGACTCCATGTTCCGGAAATGGGCAGTGCATGGACGGACTTGCTGGCAACGGGACTTGCATT
TGCCAGGATGGCTTCCAAGGTTCCATGTGTCAGTTCTGCTCCGACCCCAACAGATACGGACCCC
GGTGTAACAGAACCTGCCTGTGTGTTCATGGGACATGTGACAACAGACTGGACAGCGATGGAGC
CTGCCTGTCAGGGACATGCCGAGAAGGCACAGCTGGGCGGTTCTGTGACAAGCAGACATCAGCC
TGTGGGCCCTATGTGCAATTTTGTCACATTCATGCCTCCTGTGAATACAGCAATAAGACAGCCA
GCAACCCTCCTGGGCCTGGGGATGAAATTGAGACACAACTTCAGAAGGCAGAATGCATCCAAAC
CAGCACCGGGACATACAGCTGTGTGTGCCAGCAGGGCTGGACAGGGAACGGAAGAGACTGTGTG
GGGATCAACAACTGCCTGCTGCCTAGCTCTGGTGGCTGCCACGACAATGCCACCTGCTTATATG
TAGGCCCTGGGCAGAATGAATGTGAGTGCAAGAAAGGATTTCGAGGAAACGGGATTGACTGTGA
ACCCATCATATCATGCTTGGAACAAACAGAGAAATGTCACCCCCTGGCCACCTGTCAGTCCACT
TCCTCTGGTGTTTGGAGCTGTGTTTGCCGAGAGGGCTATGAAGGAAATGGTGTCCTGTGCTACG
GCAATGTGCTCATGGAACTGTCGTTTCTGCCTGAAGCAGCTGTGTTTTACCAGTGGATAAATAA
TGCTTCCCTGCAGTCCGTGCTGTCTACCACCTCGAATCTCACTGTCCTTGTGCCATCCCGGCGA
GCCTTTGAAGACATGGACCAGAATGAGAAAAGCTTCTGGCTGTCACGGAACAATATTCCAGCCC
TGATAAAATACCACATACTACTAGGCAAGTATGGAGTGGCTGATCTGCAGGCCCTGTCATCACC
TCACATGCTAGCGACATCCTTGCAGGGAAACTTCCTTCAGCTGGACAAGGCAGATGGGAACATC
ACAATCGAAGGGGCATCCATTGTGGATGGTGACAATGCAGCCACAAACGGGGTGGTCCACATCA
TCAACAAGGTGCTGGTCCCCCAAAGAGGCCTAACTGGCTCTTTACCAAGTCTACTCACCCGTCT
GGAGCAGATGCCCGACTATTCCATTTTCCGAGGTTACATTATTCATTACAACCTGGCAAGTGCA
ATCGAGTCTGCAGATGCTTATACTGTGTTCGTGCCAAACAATGAAGCCATCGAAAACTATATCA
GGGAGAAGAAAGCCACATCTCTAAAGGAAGATATTCTACGGTACCATGTGGTCCTGGGGGAAAA
GCTCCTGAAGAATGACTTGCATAACGGCATGCACCGAGAGACCATGCTGGGGTTCTCCTACCTC
CTTGCCTTCTTTCTCCGCAATGACCAGCTGTATGTAAATGAAGCTCCAATAAACTACACCAATG
TGGCCACTGATAAAGGAGTGATCCATGGTCTGGAGAAAGTTCTGGAAATTCAGAAGAACAGATG
TGACAATAATGACACCATTATTGTGAGAGGGGAGTGTGGAAAGTGTTCCCAGCAAGCCCCCTGC
CCACTCGAGACAAAACCACTTAGAGAGACGAGGAAATGCATCTATTCCATCTACTTCATGGGGA
AGAGATCCGTATTCATCGGGTGCCAGCCACAGTGTGTGAGAACCATCATTACAAGAGCCTGCTG
TGCTGGCTTCTTTGGCCCACAATGCCAAGCCTGCCCCGGGAGAGGTCAGAATGTGTGCTCTGGG
AACGGCTTCTGTCTGGACGGTGTGAATGGCACTGGCACGTGCCAGTGCGGGCTGGGCTTCAATG
GGACAGCCTGTGAAACCTGCACTGAGGGGAAGTATGGTATCCACTGCGACCAAGCATGCTCTTG
TGTCCATGGGAGATGTAGCCAAGGACCCTTGGGAGACGGCTCCTGTGACTGTGACGTCGGCTGG
CGAGGAGTGAAGTGTGACATGGAGATCACCACAGACAACTGCAACGGGACCTGTCACACCAGTG
CCAACTGCCTTCTGGATCCGGACGGCAAAGCCTCGTGCAAATGTGCGGCAGGATTCCGAGGGAA
TGGAACGGTCTGCACAGCCATCAATGCCTGTGAGACCAGCAATGGAGGATGTTCTACAAAGGCC
GACTGTAAAAGAACCACCCCAGGAAACCGGGTGTGTGTGTGCAAGGCAGGCTATACCGGCGACG
GCATCGTGTGCCTTGAAATCAACCCGTGTTTGGAGAACCATGGTGGCTGTGACAGAAATGCAGA
GTGCACACAGACAGGGCCCAACCAGGCCGTCTGTAACTGCTTGCCGAAGTACACTGGAGATGGA
AAGGTCTGCTCGCTTATCAATGTCTGCCTAACGAACAATGGCGGCTGCAGTCCATTTGCCTTCT
GCAACTACACTGAGCAAGATCAAAGGATATGTACCTGCAAGCCAGACTACACGGGTGATGGAAT
CGTCTGCCGGGGCAGCATCTACGGGGAGCTTCCCAAGAACCCCTCGACGTCCCAGTACTTCTTC
CAGTTGCAGGAGCATGCTGTCCGAGAGCTTGCTGGACCTGGCCCCTTCACCGTGTTCGCGCCCT
TGTCTAGCTCCTTCAATCATGAGCCCCGGATTAAAGACTGGGATCAGCAGGGCCTCATGTCCCA
GGTTCTTCGCTATCACGTGGTGGGCTGCCAGCAGCTGCTGCTGGACAACCTAAAAGTGACCACA
AGTGCCACGACCCTCCAAGGAGAGCCAGTTTCCATCTCTGTCTCTCAGGACACTGTGTTCATAA
ACAATGAGGCGAAGGTCCTGTCCAGTGACATCATCAGCACCAATGGCGTCATCCACGTTATAGA
CAAGTTGCTGTCTCCCAAAAACTTGCTTATCACCCCCAAAGATGCCTTGGGCAGGGTTCTGCAA
AATCTTACTACAGTGGCAGCAAACCACGGATATACCAAATTCAGCAAGTTGATACAGGACTCAG
GCTTGCTGTCAGTCATCACTGACTCCATCCACACCCCAGTCACTGTCTTCTGGCCTACGGACAA
AGCCCTGGAAGCCTTGCCCCCAGAGCAGCAGGACTTCCTGTTCAATCAAGACAACAAGGACAAG
CTGAAGTCTTACCTGAAGTTCCACGTGATCCGAGACTCCAAGGCTTTAGCTTCAGACCTCCCCA
GGTCTGCTTCCTGGAAGACCCTGCAAGGCTCAGAGCTGAGTGTGAGGTGTGGAACTGGCAGTGA
CATCGGTGAGCTCTTTCTAAACGAACAAATGTGCAGGATCATACAACGGGGACTCTTGTTTGAC
GTGGGTGTGGCCTATGGCATTGACTGCCTACTCATGAATCCTACCCTAGGTGGCCGCTGTGACA
CTTTTACTACCTTCGATATTCCGGGGGAGTGCGGGAGCTGCATCTTCACTCCCAGATGCCCACT
GAAGAGCAAGCCAAAGGGCGTGAAGAAGAAGTGTATCTACAACCCGTTACCTTTCAGGAGGAAC
GTGGAAGGCTGCCAGAACCTGTGCACCCTGGTGATCCAAACCCCCAGGTGCTGCCATGGTTACT
TCATGCCAGACTGTCAGGCCTGCCCTGGAGGACCAGATACACCGTGTAACAACCGGGGCATGTG
CCGCGATCTGTACACACCCATGGGACAGTGCCTATGCCACACCGGCTTCAACGGGACAGCCTGC
GAGCTCTGCTGGCATGGGAGATTTGGGCCTGACTGTCAGCCCTGCAGCTGCTCCGAGCATGGAC
AGTGTGATGAGGGGATCACAGGCTCCGGGGAGTGCCTCTGTGAAACAGGGTGGACAGGCCGCTT
CTGTGACACTCCCACAGCTGTGATTCCAGTGTGCACACCTGCTTGCTCCGTGCACGCCACCTGT
ACGGAGAACAACGCGTGTGTGTGTAACTTGAACTACGAAGGTGACGGACTCACATGCACAGTCG
TGGACTTCTGCAAACAGAACAACGGGGGCTGTGCGAAGGTCGCTAAGTGCTCCCAGAAAGGCAC
CCAAGTCTCTTGCAGCTGCAAGAAAGGCTACAAGGGGGATGGCTACAGCTGCATAGAGATAGAC
CCCTGTGCAGACGGTGTCAACGGGGGATGCCATGAGCACGCCACCTGCAGGATGACGGGCCCAG
GCAAGCATAAGTGTGAATGTAAAAGTCACTATGTCGGGGACGGAGTGGACTGTGAGCCTGAGCA
GCTGCCGCTCGACCGTTGCTTACAGGACAACGGACAGTGCCACCCAGATGCCAGCTGTGCAGAC
CTTCACTTCCAGGACACGACCGTAGGAGTATTCCATCTACGCTCCCCACTGGGCCAGTACAAAC
TGACATTTGACAAAGCCAAAGAAGCCTGTGCCAAAGAAGCTGCGACCATAGCCACCTACAACCA
GCTCTCCTATGCCCAGAAGGCCAAGTATCACCTGTGCTCGGCCGGCTGGCTGGAGAGTGGGCGG
GTTGCCTACCCCACGACCTATGCCTCTCAGAAGTGTGGTGCAAACGTTGTTGGGATCGTAGACT
ACGGATCCAGGGCCAACAAGAGTGAAATGTGGGATGTCTTCTGTTACCGGATGAAAGATGTGAA
CTGCACCTGCAAGGCAGGCTATGTGGGAGATGGCTTCTCGTGCAGTGGGAACCTGCTGCAGGTC
CTCATGTCCTTCCCCTCGCTCACAAACTTCCTGACAGAGGTGCTGGCTTTTTCCAAGAGCTCAG
CCCGAGGACAGGCATTTTTGAAACACCTGACTGACCTGTCCATCCGCGGCACCCTGTTTGTGCC
ACAGAACAGTGGGCTACCGGGAAATAAGAGCCTGTCAGGCCGGGACATTGAGCACCACCTCACT
AATGTCAACGTCTCCTTTTACAATGACCTTGTCAATGGTACCTTTCTGAGGACTATGCTGGGAA
GCCAACTGCTCATTACCTCCAGCCAGGACCAGCTCCACCAAGAGACCAGGTTTGTGGATGGAAG
ATCCATTCTGCAGTGGGACATCATCGCCGCCAATGGAATCCTCCATATTATTTCTGAACCTTTG
AGAGCTCCTCCCACGGCAGCAACGGCTGCCCACTCTGGCCTGGGGACAGGTATATTCTGTGCCG
TCGTCCTGGTCACTGGTGCGATTGCTCTGGCTGCTTACTCTTACTTCCGGCTAAAGCAGCGAAC
CACTGGTTTCCAGCGTTTTGAGTCAGAAGAGGACATTGATGTCTTGGCTTTTGGCAAGCAGCAG
CCCAAGAATATCGCAAACCCTCTGTATGAGACCTCAGCGCCGGCACCCCCAGAGTCCTCCTGTG
ACCCCTTCACAGACCCTGGAGAACAGGATCTGGAGGACAGCGACCCTCTGGGGGCACTGCGGTC
CTGA

hide sequence

RefSeq Acc Id:

XM_039078515 ⟹ XP_038934443

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	23,136,938 - 23,320,691 (-)	NCBI
mRatBN7.2	7	21,249,426 - 21,433,031 (-)	NCBI

RefSeq Acc Id:

XM_039078516 ⟹ XP_038934444

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	23,136,938 - 23,320,691 (-)	NCBI
mRatBN7.2	7	21,249,426 - 21,433,031 (-)	NCBI

RefSeq Acc Id:

XM_063263071 ⟹ XP_063119141

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	23,136,938 - 23,342,633 (-)	NCBI

RefSeq Acc Id:

XM_063263072 ⟹ XP_063119142

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	23,136,938 - 23,320,692 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001233286	(Get FASTA)	NCBI Sequence Viewer
	XP_038934443	(Get FASTA)	NCBI Sequence Viewer
	XP_038934444	(Get FASTA)	NCBI Sequence Viewer
	XP_063119141	(Get FASTA)	NCBI Sequence Viewer
	XP_063119142	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG13634	(Get FASTA)	NCBI Sequence Viewer
	ADM89077	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000056294
	ENSRNOP00000091563
GenBank Protein	Q8CFM6	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001233286 ⟸ NM_001246357
- Peptide Label:	precursor
- UniProtKB:	E0X583 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGRSKLFLSMLLPLIPLFLGLVVQNACSPTEGPELAKRCDKKSTLTIKTECQSCSANFAVKCPD GYIKVTSGSAGVRDCRYSLDIQSYVLAIPGCRHICRKDYLQPQCCPGHWGPDCMECPGGARAPC GGRGVCDEGMEGTGSCSCQAGFSGTACEACATDNVFGPNCSAVCSCVHGVCNSGLNGDGTCECL SAYRGPKCDKPIPECATLLCPENSRCSPSSKDETKLQCKCLPNYEGDGHNCKPINPCLKTICHP HASCSYLGPNRHSCICQKGYQGDGQVCLPVDPCQTNYGKCPPESTVCKYDGPGQSHCECKEHYR NFVPGVGCSMTDICESNNPCHKNANCSTVSPGKTKCTCQKGYVGDGLNCYGNIMQRLRELNTEP RGMWQGQLTSFISILDRTYAWPLSNLGPFTVLLPSDKGLKGVDVKELLMDKEAARYFAKLHIIA GQMSMEQMYHLDTFYTLTGKSGEIFNKDKDNQLKLKLHGSKVVKIIQGNIVASNGLVHILDRAM DKTEPTFASNPQQTIMAMLQPRYGRFRSLLEKTNVGQILDEGGPYTIFVPSNEALSNMKADILD YLLSPEGSRKLLELVRYHIVAFTQLEVATLVSTPHIRSMANQIIKFNITSKGQILANNVAMDET EVAAKNGRIYTLTGVLIPPSILPILPHRCNETKIELKLGTCVSCSTKHWSKCPADSKPATIFSS CFYSSRVRNLKSGCARYCNVTVEIPRCCKGFFGPDCTPCPGGFLTPCSGNGQCMDGLAGNGTCI CQDGFQGSMCQFCSDPNRYGPRCNRTCLCVHGTCDNRLDSDGACLSGTCREGTAGRFCDKQTSA CGPYVQFCHIHASCEYSNKTASNPPGPGDEIETQLQKAECIQTSTGTYSCVCQQGWTGNGRDCV GINNCLLPSSGGCHDNATCLYVGPGQNECECKKGFRGNGIDCEPIISCLEQTEKCHPLATCQST SSGVWSCVCREGYEGNGVLCYGNVLMELSFLPEAAVFYQWINNASLQSVLSTTSNLTVLVPSRR AFEDMDQNEKSFWLSRNNIPALIKYHILLGKYGVADLQALSSPHMLATSLQGNFLQLDKADGNI TIEGASIVDGDNAATNGVVHIINKVLVPQRGLTGSLPSLLTRLEQMPDYSIFRGYIIHYNLASA IESADAYTVFVPNNEAIENYIREKKATSLKEDILRYHVVLGEKLLKNDLHNGMHRETMLGFSYL LAFFLRNDQLYVNEAPINYTNVATDKGVIHGLEKVLEIQKNRCDNNDTIIVRGECGKCSQQAPC PLETKPLRETRKCIYSIYFMGKRSVFIGCQPQCVRTIITRACCAGFFGPQCQACPGRGQNVCSG NGFCLDGVNGTGTCQCGLGFNGTACETCTEGKYGIHCDQACSCVHGRCSQGPLGDGSCDCDVGW RGVKCDMEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFRGNGTVCTAINACETSNGGCSTKA DCKRTTPGNRVCVCKAGYTGDGIVCLEINPCLENHGGCDRNAECTQTGPNQAVCNCLPKYTGDG KVCSLINVCLTNNGGCSPFAFCNYTEQDQRICTCKPDYTGDGIVCRGSIYGELPKNPSTSQYFF QLQEHAVRELAGPGPFTVFAPLSSSFNHEPRIKDWDQQGLMSQVLRYHVVGCQQLLLDNLKVTT SATTLQGEPVSISVSQDTVFINNEAKVLSSDIISTNGVIHVIDKLLSPKNLLITPKDALGRVLQ NLTTVAANHGYTKFSKLIQDSGLLSVITDSIHTPVTVFWPTDKALEALPPEQQDFLFNQDNKDK LKSYLKFHVIRDSKALASDLPRSASWKTLQGSELSVRCGTGSDIGELFLNEQMCRIIQRGLLFD VGVAYGIDCLLMNPTLGGRCDTFTTFDIPGECGSCIFTPRCPLKSKPKGVKKKCIYNPLPFRRN VEGCQNLCTLVIQTPRCCHGYFMPDCQACPGGPDTPCNNRGMCRDLYTPMGQCLCHTGFNGTAC ELCWHGRFGPDCQPCSCSEHGQCDEGITGSGECLCETGWTGRFCDTPTAVIPVCTPACSVHATC TENNACVCNLNYEGDGLTCTVVDFCKQNNGGCAKVAKCSQKGTQVSCSCKKGYKGDGYSCIEID PCADGVNGGCHEHATCRMTGPGKHKCECKSHYVGDGVDCEPEQLPLDRCLQDNGQCHPDASCAD LHFQDTTVGVFHLRSPLGQYKLTFDKAKEACAKEAATIATYNQLSYAQKAKYHLCSAGWLESGR VAYPTTYASQKCGANVVGIVDYGSRANKSEMWDVFCYRMKDVNCTCKAGYVGDGFSCSGNLLQV LMSFPSLTNFLTEVLAFSKSSARGQAFLKHLTDLSIRGTLFVPQNSGLPGNKSLSGRDIEHHLT NVNVSFYNDLVNGTFLRTMLGSQLLITSSQDQLHQETRFVDGRSILQWDIIAANGILHIISEPL RAPPTAATAAHSGLGTGIFCAVVLVTGAIALAAYSYFRLKQRTTGFQRFESEEDIDVLAFGKQQ PKNIANPLYETSAPAPPESSCDPFTDPGEQDLEDSDPLGALRS hide sequence

Ensembl Acc Id:

ENSRNOP00000056294 ⟸ ENSRNOT00000059538

RefSeq Acc Id:	XP_038934444 ⟸ XM_039078516
- Peptide Label:	isoform X3
- UniProtKB:	F1LZZ6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934443 ⟸ XM_039078515
- Peptide Label:	isoform X1
- UniProtKB:	F1LZZ6 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000078245 ⟸ ENSRNOT00000112055

Ensembl Acc Id:

ENSRNOP00000091563 ⟸ ENSRNOT00000099162

RefSeq Acc Id:	XP_063119141 ⟸ XM_063263071
- Peptide Label:	isoform X2
- UniProtKB:	F1LZZ6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063119142 ⟸ XM_063263072
- Peptide Label:	isoform X4
- UniProtKB:	F1LZZ6 (UniProtKB/TrEMBL)

Protein Domains

EGF-like FAS1 Laminin EGF-like Link

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8CFM6-F1-model_v2	AlphaFold	Q8CFM6	1-1431	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628822	AgrOrtholog
BioCyc Gene	G2FUF-34542	BioCyc
Ensembl Genes	ENSRNOG00000038948	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000059538	ENTREZGENE
	ENSRNOT00000099162	ENTREZGENE
Gene3D-CATH	2.30.180.10	UniProtKB/Swiss-Prot
	3.10.100.10	UniProtKB/Swiss-Prot
	Laminin	UniProtKB/Swiss-Prot
	Tie2 ligand-binding domain superfamily	UniProtKB/Swiss-Prot
InterPro	C-type_lectin-like/link_sf	UniProtKB/Swiss-Prot
	CTDL_fold	UniProtKB/Swiss-Prot
	EGF-like_Ca-bd_dom	UniProtKB/Swiss-Prot
	EGF-like_dom	UniProtKB/Swiss-Prot
	EGF_dom	UniProtKB/Swiss-Prot
	FAS1_dom_sf	UniProtKB/Swiss-Prot
	FAS1_domain	UniProtKB/Swiss-Prot
	Growth_fac_rcpt_cys_sf	UniProtKB/Swiss-Prot
	Laminin_EGF	UniProtKB/Swiss-Prot
	Link_dom	UniProtKB/Swiss-Prot
NCBI Gene	282580	ENTREZGENE
PANTHER	STABILIN	UniProtKB/Swiss-Prot
	STABILIN-2	UniProtKB/Swiss-Prot
Pfam	EGF_3	UniProtKB/Swiss-Prot
	Fasciclin	UniProtKB/Swiss-Prot
	Xlink	UniProtKB/Swiss-Prot
PhenoGen	Stab2	PhenoGen
PROSITE	EGF_1	UniProtKB/Swiss-Prot
	EGF_2	UniProtKB/Swiss-Prot
	EGF_3	UniProtKB/Swiss-Prot
	EGF_LAM_1	UniProtKB/Swiss-Prot
	FAS1	UniProtKB/Swiss-Prot
	LINK_1	UniProtKB/Swiss-Prot
	LINK_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000038948	RatGTEx
SMART	EGF	UniProtKB/Swiss-Prot
	EGF_CA	UniProtKB/Swiss-Prot
	FAS1	UniProtKB/Swiss-Prot
	LINK	UniProtKB/Swiss-Prot
Superfamily-SCOP	EGF/Laminin	UniProtKB/Swiss-Prot
	SSF56436	UniProtKB/Swiss-Prot
	SSF57184	UniProtKB/Swiss-Prot
	SSF82153	UniProtKB/Swiss-Prot
UniProt	A0A8I6G2H4_RAT	UniProtKB/TrEMBL
	A0A8I6GJ29_RAT	UniProtKB/TrEMBL
	E0X583	ENTREZGENE, UniProtKB/TrEMBL
	F1LZZ6	ENTREZGENE, UniProtKB/TrEMBL
	Q8CFM6	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-29	Stab2	stabilin 2	RGD1560941	similar to stabilin-2	Data merged from RGD:1560941	737654	PROVISIONAL
2013-05-24	Stab2	stabilin 2	LOC691926	similar to Stabilin-2 precursor (Hyaluronan receptor for endocytosis)	Data merged from RGD:1593355	1643240	APPROVED
2008-04-30	RGD1560941	similar to stabilin-2	RGD1560941_predicted	similar to stabilin-2 (predicted)	'predicted' is removed	2292626	APPROVED
2006-11-20	LOC691926	similar to Stabilin-2 precursor (Hyaluronan receptor for endocytosis)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-07	RGD1560941_predicted	similar to stabilin-2 (predicted)	LOC299701	similar to stabilin-2	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC299701	similar to stabilin-2			Symbol and Name status set to provisional	70820	PROVISIONAL
2004-09-10	Stab2	stabilin 2			Symbol and Name status set to approved	1299863	APPROVED
2003-02-27	Stab2	stabilin 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD