Mx2 (MX dynamin like GTPase 2) - Rat Genome Database

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Gene: Mx2 (MX dynamin like GTPase 2) Rattus norvegicus
Analyze
Symbol: Mx2
Name: MX dynamin like GTPase 2
RGD ID: 628821
Description: Predicted to enable GTP binding activity; GTPase activity; and microtubule binding activity. Involved in response to virus. Located in cytoplasm. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate cancer. Orthologous to several human genes including MX1 (MX dynamin like GTPase 1); PARTICIPATES IN influenza A pathway; measles pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: interferon-induced GTP-binding protein Mx2; interferon-induced GTP-binding protein Mx3; Mx3; myxovirus (influenza virus) resistance 2; myxovirus (influenza virus) resistance 3; myxovirus resistance protein 2; myxovirus resistance protein 3
RGD Orthologs
Human
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,375,101 - 50,399,373 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1150,375,191 - 50,402,478 (+)EnsemblGRCr8
mRatBN7.21136,905,698 - 36,936,308 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,906,111 - 36,930,342 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1145,604,887 - 45,630,454 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,276,267 - 38,301,834 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,436,195 - 37,461,762 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01138,035,306 - 38,066,185 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,035,450 - 38,059,950 (+)Ensemblrn6Rnor6.0
Rnor_5.01141,545,958 - 41,570,577 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41137,548,650 - 37,572,717 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1136,790,647 - 36,814,700 (+)NCBICelera
RGSC_v3.11137,608,291 - 37,630,303 (+)NCBI
RH 3.4 Map11263.01RGD
Cytogenetic Map11q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aconitine  (EXP)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
amphotericin B  (ISO)
atrazine  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bromuconazole  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
corn oil  (EXP)
cyclophosphamide  (ISO)
decabromodiphenyl ether  (EXP)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dieldrin  (EXP)
diethyl maleate  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
fentanyl  (EXP)
formaldehyde  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
irinotecan  (ISO)
lead diacetate  (EXP)
lipopolysaccharide  (ISO)
metformin  (EXP)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
okadaic acid  (ISO)
organophosphorus compound  (EXP)
orphenadrine  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (EXP)
perfluorooctanoic acid  (ISO)
phenformin  (EXP)
phenobarbital  (EXP)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tamibarotene  (ISO)
tauroursodeoxycholic acid  (EXP)
temozolomide  (ISO)
testosterone  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
tofacitinib  (ISO)
topotecan  (EXP)
triclosan  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)
zinc atom  (EXP)
zinc sulfate  (ISO)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IDA,IEA,ISO)
exocytic vesicle  (ISO)
microtubule  (IBA)
nuclear pore  (ISO)
nucleus  (IBA,ISO)
plasma membrane  (IBA)
presynapse  (IEA)
synapse  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
3. Activity of rat Mx proteins against a rhabdovirus. Meier E, etal., J Virol 1990 Dec;64(12):6263-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9371647   PMID:12477932   PMID:14687945   PMID:15047845   PMID:15767791   PMID:16202617   PMID:16780588   PMID:18504258   PMID:20167191   PMID:20428112   PMID:21478870   PMID:21859714  
PMID:24500530   PMID:25295396   PMID:25416956   PMID:28064310   PMID:31505169  


Genomics

Comparative Map Data
Mx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,375,101 - 50,399,373 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1150,375,191 - 50,402,478 (+)EnsemblGRCr8
mRatBN7.21136,905,698 - 36,936,308 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,906,111 - 36,930,342 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1145,604,887 - 45,630,454 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,276,267 - 38,301,834 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,436,195 - 37,461,762 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01138,035,306 - 38,066,185 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,035,450 - 38,059,950 (+)Ensemblrn6Rnor6.0
Rnor_5.01141,545,958 - 41,570,577 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41137,548,650 - 37,572,717 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1136,790,647 - 36,814,700 (+)NCBICelera
RGSC_v3.11137,608,291 - 37,630,303 (+)NCBI
RH 3.4 Map11263.01RGD
Cytogenetic Map11q12NCBI
MX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382141,362,027 - 41,409,393 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2141,361,957 - 41,409,417 (+)Ensemblhg38GRCh38
GRCh372142,733,954 - 42,781,320 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,655,820 - 41,702,739 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342141,655,819 - 41,702,739NCBI
Celera2127,932,197 - 27,979,096 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2128,202,853 - 28,249,753 (+)NCBIHuRef
CHM1_12142,294,753 - 42,341,669 (+)NCBICHM1_1
T2T-CHM13v2.02139,750,638 - 39,798,083 (+)NCBIT2T-CHM13v2.0
MX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22237,443,072 - 37,490,730 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12132,297,379 - 32,344,569 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02127,696,457 - 27,744,105 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12141,024,562 - 41,071,653 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,032,681 - 41,071,653 (+)EnsemblpanPan2panpan1.1
MX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13135,860,596 - 35,883,607 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3135,860,590 - 35,951,350 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3135,005,886 - 35,038,055 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03135,368,501 - 35,400,678 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3135,367,708 - 35,468,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13135,264,320 - 35,296,463 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03135,242,367 - 35,274,518 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03135,736,514 - 35,768,675 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
MX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13204,798,629 - 204,831,957 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113204,798,633 - 204,821,612 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213215,036,188 - 215,059,001 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,281,752 - 85,326,736 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl285,289,689 - 85,326,735 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605413,133,992 - 13,178,868 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Mx2
79 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:236
Count of miRNA genes:176
Interacting mature miRNAs:194
Transcripts:ENSRNOT00000002695
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
RH94601  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map11263.01UniSTS
Cytogenetic Map11q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002695   ⟹   ENSRNOP00000002695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1138,035,696 - 38,059,577 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083067   ⟹   ENSRNOP00000075302
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1150,375,191 - 50,400,082 (+)Ensembl
mRatBN7.2 Ensembl1136,906,111 - 36,930,342 (+)Ensembl
Rnor_6.0 Ensembl1138,035,450 - 38,059,312 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087603   ⟹   ENSRNOP00000075496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1150,375,291 - 50,402,478 (+)Ensembl
mRatBN7.2 Ensembl1136,906,111 - 36,930,342 (+)Ensembl
Rnor_6.0 Ensembl1138,035,611 - 38,059,950 (+)Ensembl
RefSeq Acc Id: NM_134350   ⟹   NP_599177
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,375,306 - 50,399,373 (+)NCBI
mRatBN7.21136,905,903 - 36,929,972 (+)NCBI
Rnor_6.01138,035,513 - 38,059,580 (+)NCBI
Rnor_5.01141,545,958 - 41,570,577 (+)NCBI
RGSC_v3.41137,548,650 - 37,572,717 (+)RGD
Celera1136,790,647 - 36,814,700 (+)RGD
Sequence:
RefSeq Acc Id: XM_039088055   ⟹   XP_038943983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,375,101 - 50,399,373 (+)NCBI
mRatBN7.21136,905,698 - 36,930,468 (+)NCBI
RefSeq Acc Id: XM_063270316   ⟹   XP_063126386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,375,245 - 50,399,373 (+)NCBI
RefSeq Acc Id: XM_063270317   ⟹   XP_063126387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,375,245 - 50,399,373 (+)NCBI
RefSeq Acc Id: XM_063270318   ⟹   XP_063126388
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,375,298 - 50,399,373 (+)NCBI
RefSeq Acc Id: NP_599177   ⟸   NM_134350
- UniProtKB: Q499Q3 (UniProtKB/TrEMBL),   A6IQG6 (UniProtKB/TrEMBL),   A0A0G2KA85 (UniProtKB/TrEMBL),   A0A0G2KAR4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075496   ⟸   ENSRNOT00000087603
Ensembl Acc Id: ENSRNOP00000002695   ⟸   ENSRNOT00000002695
Ensembl Acc Id: ENSRNOP00000075302   ⟸   ENSRNOT00000083067
RefSeq Acc Id: XP_038943983   ⟸   XM_039088055
- Peptide Label: isoform X1
- UniProtKB: Q499Q3 (UniProtKB/TrEMBL),   A6IQG6 (UniProtKB/TrEMBL),   A0A0G2KA85 (UniProtKB/TrEMBL),   A0A0G2KAR4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126386   ⟸   XM_063270316
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KAR4 (UniProtKB/TrEMBL),   A6IQG6 (UniProtKB/TrEMBL),   Q499Q3 (UniProtKB/TrEMBL),   A0A0G2KA85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126387   ⟸   XM_063270317
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KAR4 (UniProtKB/TrEMBL),   A6IQG6 (UniProtKB/TrEMBL),   Q499Q3 (UniProtKB/TrEMBL),   A0A0G2KA85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126388   ⟸   XM_063270318
- Peptide Label: isoform X1
- UniProtKB: A0A0G2KAR4 (UniProtKB/TrEMBL),   A6IQG6 (UniProtKB/TrEMBL),   Q499Q3 (UniProtKB/TrEMBL),   A0A0G2KA85 (UniProtKB/TrEMBL)
Protein Domains
Dynamin-type G   GED

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18589-F1-model_v2 AlphaFold P18589 1-659 view protein structure
AF-P18590-F1-model_v2 AlphaFold P18590 1-659 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698098
Promoter ID:EPDNEW_R8618
Type:multiple initiation site
Name:Mx2_1
Description:MX dynamin like GTPase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01138,035,498 - 38,035,558EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628821 AgrOrtholog
BioCyc Gene G2FUF-21683 BioCyc
Ensembl Genes ENSRNOG00000001963 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000083067 ENTREZGENE
  ENSRNOT00000087603 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
  Dynamin, middle domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7938638 IMAGE-MGC_LOAD
InterPro Dynamin_central UniProtKB/Swiss-Prot
  Dynamin_GTPase UniProtKB/Swiss-Prot
  Dynamin_GTPase_CS UniProtKB/Swiss-Prot
  Dynamin_N UniProtKB/Swiss-Prot
  Dynamin_SF UniProtKB/Swiss-Prot
  G_DYNAMIN_dom UniProtKB/Swiss-Prot
  GED UniProtKB/Swiss-Prot
  GED_dom UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
MGC_CLONE MGC:124566 IMAGE-MGC_LOAD
NCBI Gene 286918 ENTREZGENE
PANTHER INTERFERON-INDUCED GTP-BINDING PROTEIN MX1 UniProtKB/Swiss-Prot
  PTHR11566 UniProtKB/Swiss-Prot
Pfam Dynamin_M UniProtKB/Swiss-Prot
  Dynamin_N UniProtKB/Swiss-Prot
  GED UniProtKB/Swiss-Prot
PhenoGen Mx2 PhenoGen
PRINTS DYNAMIN UniProtKB/Swiss-Prot
PROSITE G_DYNAMIN_1 UniProtKB/Swiss-Prot
  G_DYNAMIN_2 UniProtKB/Swiss-Prot
  GED UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001963 RatGTEx
SMART DYNc UniProtKB/Swiss-Prot
  GED UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2KA85 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2KAR4 ENTREZGENE, UniProtKB/TrEMBL
  A6IQG6 ENTREZGENE, UniProtKB/TrEMBL
  MX2_RAT UniProtKB/Swiss-Prot
  MX3_RAT UniProtKB/Swiss-Prot
  P18589 ENTREZGENE
  P18590 ENTREZGENE
  Q499Q3 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-29 Mx2  MX dynamin like GTPase 2  Mx2  myxovirus (influenza virus) resistance 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-04-21 Mx2  myxovirus (influenza virus) resistance 2  Mx3  myxovirus (influenza virus) resistance 3  Data merged from RGD:621298 737654 APPROVED
2003-02-27 Mx2  myxovirus (influenza virus) resistance 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Mx3  myxovirus (influenza virus) resistance 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression stimulated by alpha/beta interferon 728936