Gene: Trpc7 (transient receptor potential cation channel, subfamily C, member 7) Rattus norvegicus
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Symbol:
Trpc7
Name:
transient receptor potential cation channel, subfamily C, member 7
RGD ID:
628820
Description:
Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within calcium ion transport and manganese ion transport. Located in perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human TRPC7 (transient receptor potential cation channel subfamily C member 7); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
capacitative calcium channel TRPC7; short transient receptor potential channel 7
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
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Orthologs 1
Homo sapiens (human):
TRPC7 (transient receptor potential cation channel subfamily C member 7)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):
Trpc7 (transient receptor potential cation channel, subfamily C, member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Trpc7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
TRPC7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
TRPC7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Trpc7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
TRPC7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
TRPC7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Trpc7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Trpc7 (transient receptor potential cation channel subfamily C member 7)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
SLC5A1 (solute carrier family 5 member 1)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
TRPC7 (transient receptor potential cation channel subfamily C member 7)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Trpc7 (transient receptor potential cation channel, subfamily C, member 7)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
trpc7a (transient receptor potential cation channel, subfamily C, member 7a)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
trpc7a (transient receptor potential cation channel, subfamily C, member 7a)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
trpc7b (transient receptor potential cation channel, subfamily C, member 7b)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|PhylomeDB)
Danio rerio (zebrafish):
trpc7b (transient receptor potential cation channel, subfamily C, member 7b)
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
trp-1
Alliance
DIOPT (OMA|PANTHER)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 17 7,707,954 - 7,839,064 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 17 7,714,505 - 7,838,745 (+) Ensembl GRCr8 mRatBN7.2 17 7,708,911 - 7,833,435 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 17 7,709,583 - 7,833,435 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 17 7,728,782 - 7,851,532 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 17 9,261,227 - 9,383,024 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 17 7,725,168 - 7,847,919 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 17 8,134,267 - 8,280,360 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 17 8,135,251 - 8,279,515 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 17 10,316,554 - 10,456,609 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 17 13,660,133 - 13,781,358 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 17 7,806,368 - 7,928,485 (+) NCBI Celera RGSC_v3.1 17 13,749,821 - 13,771,093 (+) NCBI Cytogenetic Map 17 p14 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Trpc7 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Trpc7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Trpc7 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Trpc7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Trpc7 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Trpc7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Trpc7 Rat 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO Trpc7 (Mus musculus) 6480464 2,3',4,4',5-pentachlorobiphenyl results in increased expression of TRPC7 mRNA CTD PMID:31388691 Trpc7 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of TRPC7 mRNA CTD PMID:32109520 Trpc7 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Trpc7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Trpc7 Rat 2-palmitoylglycerol increases expression ISO TRPC7 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of TRPC7 mRNA CTD PMID:37199045 Trpc7 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of TRPC7 mRNA CTD PMID:24780913 Trpc7 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of TRPC7 mRNA CTD PMID:25825206 Trpc7 Rat aflatoxin B1 decreases methylation ISO TRPC7 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of TRPC7 gene CTD PMID:27153756 Trpc7 Rat antirheumatic drug decreases expression ISO TRPC7 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of TRPC7 mRNA CTD PMID:24449571 Trpc7 Rat aristolochic acid A increases expression ISO TRPC7 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of TRPC7 mRNA CTD PMID:33212167 Trpc7 Rat ATP increases activity ISO Trpc7 (Mus musculus) 6480464 Adenosine Triphosphate results in increased activity of TRPC7 protein CTD PMID:19289841 Trpc7 Rat Azoxymethane multiple interactions ISO Trpc7 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TRPC7 more ... CTD PMID:29950665 Trpc7 Rat benzo[a]pyrene decreases methylation ISO TRPC7 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of TRPC7 5' UTR CTD PMID:27901495 Trpc7 Rat benzo[a]pyrene affects methylation ISO TRPC7 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of TRPC7 exon; Benzo(a)pyrene affects the methylation of TRPC7 promoter CTD PMID:27901495|PMID:30157460 Trpc7 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TRPC7 mRNA CTD PMID:25181051 Trpc7 Rat CGP 52608 multiple interactions ISO TRPC7 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to TRPC7 gene] CTD PMID:28238834 Trpc7 Rat dextran sulfate multiple interactions ISO Trpc7 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TRPC7 more ... CTD PMID:29950665 Trpc7 Rat folic acid decreases expression ISO Trpc7 (Mus musculus) 6480464 Folic Acid results in decreased expression of TRPC7 mRNA CTD PMID:25629700 Trpc7 Rat indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TRPC7 mRNA CTD PMID:22129741 Trpc7 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of TRPC7 gene CTD PMID:35440735 Trpc7 Rat microcystin RR increases expression ISO TRPC7 (Homo sapiens) 6480464 microcystin RR results in increased expression of TRPC7 protein CTD PMID:19111056 Trpc7 Rat ML-7 increases activity ISO Trpc7 (Mus musculus) 6480464 ML 7 results in increased activity of TRPC7 protein CTD PMID:17603544 Trpc7 Rat N-acetyl-L-cysteine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TRPC7 mRNA CTD PMID:22129741 Trpc7 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TRPC7 mRNA CTD PMID:22129741 Trpc7 Rat PCB138 multiple interactions ISO Trpc7 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Trpc7 Rat pirinixic acid increases expression ISO Trpc7 (Mus musculus) 6480464 pirinixic acid results in increased expression of TRPC7 mRNA CTD PMID:20813756 Trpc7 Rat prostaglandin E2 increases response to substance ISO TRPC7 (Homo sapiens) 6480464 TRPC7 results in increased susceptibility to Dinoprostone CTD PMID:16790996 Trpc7 Rat titanium dioxide multiple interactions ISO Trpc7 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TRPC7 more ... CTD PMID:29950665 Trpc7 Rat titanium dioxide decreases methylation ISO Trpc7 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of TRPC7 gene CTD PMID:35295148 Trpc7 Rat UTP increases activity ISO Trpc7 (Mus musculus) 6480464 Uridine Triphosphate results in increased activity of TRPC7 protein CTD PMID:19289841 Trpc7 Rat vinclozolin decreases methylation EXP 6480464 vinclozolin results in decreased methylation of TRPC7 gene CTD PMID:31682807