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Gene: Ush2a (usherin) Rattus norvegicus

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Symbol:

Ush2a

Name:

usherin

RGD ID:

628777

Description:

Predicted to enable collagen binding activity; identical protein binding activity; and myosin binding activity. Involved in retina development in camera-type eye. Located in several cellular components, including photoreceptor connecting cilium; photoreceptor inner segment; and stereocilium. Human ortholog(s) of this gene implicated in Usher syndrome (multiple); nonsyndromic deafness; and retinitis pigmentosa (multiple). Orthologous to human USH2A (usherin); PARTICIPATES IN auditory mechanotransduction pathway; retinitis pigmentosa pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC102554234; LOC289369; RGD1560269; similar to usherin isoform B; Usher syndrome 2A; Usher syndrome 2A (autosomal recessive, mild); Usher syndrome 2A (autosomal recessive, mild) homolog; Usher syndrome 2A (autosomal recessive, mild) homolog (human); Usher syndrome 2A homolog; Usher syndrome 2A homolog (human); usher syndrome type IIa protein homolog; usher syndrome type-2A protein homolog; usherin-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	USH2A (usherin)	HGNC	Ensembl, HomoloGene, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Ush2a (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ush2a (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	USH2A (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	USH2A (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ush2a (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	USH2A (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	USH2A (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ush2a (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Ush2a (usherin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	GPATCH2 (G-patch domain containing 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Ush2a (usherin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	USH2A (usherin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	USH2A (usherin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ush2a (Usher syndrome 2A (autosomal recessive, mild))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	102,368,783 - 103,035,230 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	102,368,783 - 103,035,217 (+)	Ensembl				GRCr8
mRatBN7.2	13	99,837,445 - 100,503,935 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	99,837,445 - 100,503,922 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	102,352,932 - 103,019,370 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	103,742,004 - 104,408,169 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	100,938,790 - 101,610,718 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	106,750,738 - 107,434,195 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	106,751,625 - 107,427,329 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	111,395,505 - 112,057,548 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	104,481,807 - 104,606,485 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	99,331,812 - 99,994,577 (+)	NCBI		Celera
RGSC_v3.1	13	104,670,849 - 104,795,529 (+)	NCBI
Cytogenetic Map	13	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

autosomal dominant nonsyndromic deafness 36 (ISO)

Bardet-Biedl syndrome (ISO)

blindness (ISO)

cone-rod dystrophy (ISO)

cone-rod dystrophy 3 (ISO)

congenital stationary night blindness (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

Hearing Loss (ISO)

Joubert syndrome (ISO)

Leber congenital amaurosis (ISO)

macular degeneration (ISO)

nonsyndromic deafness (ISO)

optic atrophy (ISO)

prostate cancer (ISO)

Pulmonary Surfactant Metabolism Dysfunction 2 (ISO)

retinal degeneration (ISO)

retinitis pigmentosa (ISO)

retinitis pigmentosa 1 (ISO)

retinitis pigmentosa 39 (ISO)

retinitis pigmentosa-deafness syndrome (ISO)

sensorineural hearing loss (ISO)

Usher syndrome (ISO)

Usher syndrome type 1 (ISO)

Usher syndrome type 2 (ISO)

Usher syndrome type 2A (ISO,ISS)

Usher syndrome type 3A (ISO)

Vision Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

5-azacytidine (ISO)

5-fluorouracil (ISO)

acetamide (EXP)

acrolein (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

ammonium chloride (EXP)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

CGP 52608 (ISO)

doxorubicin (ISO)

fenthion (ISO)

folic acid (ISO)

glyphosate (EXP)

methamphetamine (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

N,N-diethyl-m-toluamide (EXP)

O-methyleugenol (ISO)

okadaic acid (ISO)

permethrin (EXP)

serpentine asbestos (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ morphogenesis (IBA)

establishment of protein localization (ISS)

hair cell differentiation (IEA,ISO)

inner ear receptor cell differentiation (IEA,ISO)

maintenance of animal organ identity (IEA,ISO)

photoreceptor cell maintenance (IEA,ISO)

retina development in camera-type eye (IEP)

sensory organ development (IEA)

sensory perception of light stimulus (IEA,ISO)

sensory perception of sound (IEA,ISO)

system development (IEA)

tissue development (IBA)

visual perception (IEA)

Cellular Component

basement membrane (IBA,IEA,ISO)

cytoplasm (IEA,ISO)

extracellular region (IEA)

neuronal cell body (IDA)

periciliary membrane compartment (IEA,ISO,ISS)

photoreceptor connecting cilium (IDA,IEA)

photoreceptor inner segment (IDA,IEA)

stereocilia ankle link (IEA,ISO,ISS)

stereocilia ankle link complex (ISS)

stereocilium (IDA,IEA,ISO)

stereocilium membrane (IEA,ISO)

terminal bouton (IDA)

USH2 complex (IEA,ISO,ISS)

Molecular Function

collagen binding (IEA,ISO)

myosin binding (IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

auditory mechanotransduction pathway (ISO)

retinitis pigmentosa pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Four USH2A founder mutations underlie the majority of Usher syndrome type 2 cases among non-Ashkenazi Jews.	Auslender N, etal., Genet Test. 2008 Jun;12(2):289-94. doi: 10.1089/gte.2007.0107.
2.	Molecular and in silico analyses of the full-length isoform of usherin identify new pathogenic alleles in Usher type II patients.	Baux D, etal., Hum Mutat. 2007 Aug;28(8):781-9.
3.	Genes and mutations causing retinitis pigmentosa.	Daiger SP, etal., Clin Genet. 2013 Aug;84(2):132-41. doi: 10.1111/cge.12203. Epub 2013 Jun 19.
4.	An USH2A founder mutation is the major cause of Usher syndrome type 2 in Canadians of French origin and confirms common roots of Quebecois and Acadians.	Ebermann I, etal., Eur J Hum Genet. 2009 Jan;17(1):80-4. doi: 10.1038/ejhg.2008.143. Epub 2008 Jul 30.
5.	Mutation of a gene encoding a protein with extracellular matrix motifs in Usher syndrome type IIa.	Eudy JD, etal., Science. 1998 Jun 12;280(5370):1753-7.
6.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7.	Identification of the mouse and rat orthologs of the gene mutated in Usher syndrome type IIA and the cellular source of USH2A mRNA in retina, a target tissue of the disease.	Huang D, etal., Genomics 2002 Aug;80(2):195-203.
8.	Novel USH2A compound heterozygous mutations cause RP/USH2 in a Chinese family.	Liu X, etal., Mol Vis. 2010 Mar 17;16:454-61.
9.	Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells.	Liu X, etal., Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4413-8. Epub 2007 Mar 5.
10.	Novel mutations in the long isoform of the USH2A gene in patients with Usher syndrome type II or non-syndromic retinitis pigmentosa.	McGee TL, etal., J Med Genet. 2010 Jul;47(7):499-506. doi: 10.1136/jmg.2009.075143. Epub 2010 May 27.
11.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
12.	Mutations in myosin VIIA (MYO7A) and usherin (USH2A) in Spanish patients with Usher syndrome types I and II, respectively.	Najera C, etal., Hum Mutat. 2002 Jul;20(1):76-7.
13.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
14.	Mutational spectrum in Usher syndrome type II.	Ouyang XM, etal., Clin Genet. 2004 Apr;65(4):288-93.
15.	Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.	Reiners J, etal., Hum Mol Genet. 2005 Dec 15;14(24):3933-43. Epub 2005 Nov 21.
16.	GOA pipeline	RGD automated data pipeline
17.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
19.	Missense mutation in the USH2A gene: association with recessive retinitis pigmentosa without hearing loss.	Rivolta C, etal., Am J Hum Genet. 2000 Jun;66(6):1975-8. Epub 2000 Apr 20.
20.	Review series: The cell biology of hearing.	Schwander M, etal., J Cell Biol. 2010 Jul 12;190(1):9-20. doi: 10.1083/jcb.201001138.
21.	Usher syndrome type 2 caused by activation of an USH2A pseudoexon: implications for diagnosis and therapy.	Vache C, etal., Hum Mutat. 2012 Jan;33(1):104-8. doi: 10.1002/humu.21634. Epub 2011 Nov 16.
22.	The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.	van Wijk E, etal., Hum Mol Genet. 2006 Mar 1;15(5):751-65. Epub 2006 Jan 24.
23.	Genomic structure and identification of novel mutations in usherin, the gene responsible for Usher syndrome type IIa.	Weston MD, etal., Am J Hum Genet. 2000 Apr;66(4):1199-210. Epub 2000 Mar 22.
24.	Genetic etiology study of the non-syndromic deafness in Chinese Hans by targeted next-generation sequencing.	Yang T, etal., Orphanet J Rare Dis. 2013 Jun 14;8:85. doi: 10.1186/1750-1172-8-85.

Additional References at PubMed

PMID:10090909	PMID:12433396	PMID:14676276	PMID:15671307	PMID:16301217	PMID:17567809	PMID:17906286	PMID:20502675	PMID:21212183	PMID:24334608	PMID:25406310

Genomics

Comparative Map Data

Ush2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	102,368,783 - 103,035,230 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	102,368,783 - 103,035,217 (+)	Ensembl				GRCr8
mRatBN7.2	13	99,837,445 - 100,503,935 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	99,837,445 - 100,503,922 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	102,352,932 - 103,019,370 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	103,742,004 - 104,408,169 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	100,938,790 - 101,610,718 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	106,750,738 - 107,434,195 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	106,751,625 - 107,427,329 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	111,395,505 - 112,057,548 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	104,481,807 - 104,606,485 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	99,331,812 - 99,994,577 (+)	NCBI		Celera
RGSC_v3.1	13	104,670,849 - 104,795,529 (+)	NCBI
Cytogenetic Map	13	q26	NCBI

USH2A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	215,622,891 - 216,423,448 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	215,622,891 - 216,423,448 (-)	Ensembl			hg38	GRCh38
GRCh37	1	215,796,233 - 216,596,790 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	213,862,859 - 214,663,361 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	212,735,682 - 212,985,133	NCBI
Celera	1	189,020,056 - 189,820,422 (-)	NCBI		Celera
Cytogenetic Map	1	q41	NCBI
HuRef	1	186,470,498 - 187,272,188 (-)	NCBI		HuRef
CHM1_1	1	217,068,567 - 217,869,890 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	214,863,291 - 215,663,779 (-)	NCBI		T2T-CHM13v2.0

Ush2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	187,995,035 - 188,697,694 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	187,994,220 - 188,697,238 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	188,262,838 - 188,965,497 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	188,262,023 - 188,965,041 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	190,086,717 - 190,788,920 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	189,963,822 - 190,665,716 (+)	NCBI		MGSCv36	mm8
Celera	1	195,189,439 - 195,876,703 (+)	NCBI		Celera
Cytogenetic Map	1	H6	NCBI
cM Map	1	92.29	NCBI

Ush2a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	1,838,885 - 2,496,980 (+)	Ensembl
ChiLan1.0	NW_004955406	1,837,831 - 2,499,664 (+)	NCBI	ChiLan1.0	ChiLan1.0

USH2A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	32,981,404 - 33,782,083 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	32,939,322 - 33,739,723 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	191,193,130 - 191,994,664 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	196,048,086 - 196,850,216 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	196,048,086 - 196,850,216 (-)	Ensembl			panPan2	panpan1.1

USH2A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	11,063,221 - 11,750,444 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	11,063,817 - 11,750,444 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	11,100,934 - 11,787,913 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	11,089,431 - 11,776,697 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	11,089,576 - 11,776,697 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	11,101,486 - 11,789,687 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	11,453,699 - 12,141,739 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	11,739,438 - 12,442,329 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ush2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	60,113,945 - 60,848,953 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936628	2,123,957 - 2,858,872 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936628	2,123,917 - 2,859,958 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

USH2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	10	5,825,591 - 6,662,733 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	7,790,789 - 8,411,655 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

USH2A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	13,171,499 - 13,950,553 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	13,173,576 - 13,947,724 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	13,613,553 - 14,394,397 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ush2a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624835	49,877 - 758,640 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624835	48,213 - 758,640 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Ush2a
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	66,389,009 - 67,059,300 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Ush2a
4287 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	128
Count of miRNA genes:	103
Interacting mature miRNAs:	114
Transcripts:	ENSRNOT00000004992
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

D13Got96

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	99,917,607 - 99,917,880 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	106,835,467 - 106,835,739	NCBI	Rnor6.0
Rnor_5.0	13	111,474,382 - 111,474,654	UniSTS	Rnor5.0
RGSC_v3.4	13	104,507,255 - 104,507,528	RGD	RGSC3.4
RGSC_v3.4	13	104,507,256 - 104,507,528	UniSTS	RGSC3.4
Celera	13	99,410,109 - 99,410,381	UniSTS
RGSC_v3.1	13	104,696,299 - 104,696,571	RGD
RH 3.4 Map	13	663.2	UniSTS
RH 3.4 Map	13	663.2	RGD
RH 2.0 Map	13	731.9	RGD
Cytogenetic Map	13	q26	UniSTS

D13Got101

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RGSC_v3.4	13	104,872,569 - 104,872,815	RGD	RGSC3.4
RGSC_v3.4	13	104,872,568 - 104,872,815	UniSTS	RGSC3.4
RGSC_v3.1	13	105,061,612 - 105,061,858	RGD
RH 3.4 Map	13	687.7	UniSTS
RH 3.4 Map	13	687.7	RGD
RH 2.0 Map	13	734.2	RGD
Cytogenetic Map	13	q26	UniSTS

RH137407

Rat Assembly	Chr	Position (strand)	Source
Celera	13	99,466,887 - 99,467,074	UniSTS
RH 3.4 Map	13	682.2	UniSTS
Cytogenetic Map	13	q26	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
6	2	30	142	60	63	34	15	34	6	154	63	3	124	49	75	29	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001302219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598757	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001840774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY077844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004992 ⟹ ENSRNOP00000004992

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	102,368,783 - 103,035,217 (+)	Ensembl
mRatBN7.2 Ensembl	13	99,837,445 - 100,503,922 (+)	Ensembl
Rnor_6.0 Ensembl	13	106,751,625 - 107,427,329 (+)	Ensembl

RefSeq Acc Id:

NM_001302219 ⟹ NP_001289148

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	102,368,783 - 103,035,230 (+)	NCBI
mRatBN7.2	13	99,837,445 - 100,503,935 (+)	NCBI
Rnor_6.0	13	106,751,625 - 107,427,328 (+)	NCBI
Celera	13	99,331,812 - 99,994,577 (+)	NCBI

Sequence:

show sequence

CTGTCCTCTCTAAGGACATCCTTACTCTGTCTTCCCTGTGAAAGTGTCTGCGGTCTCCCAGAGA
TGGAGAATCTCTGTATTCAAGTGCCCAGCCTTCCCAGTGTTCATGGTGAACAGAGCATCCCTGG
ACAGTAGTTGAGGAAAGCTTTCATCAGGTGAAGAATACTTTTCTGTCATCATGTATTACCTGGC
TCTCTCATCCGGCTTCCTGGGTCAGGCCATTAAAACATCGATCCTTGCCTATTTGGCCTCAGTG
TTGCTGGCTGCCTCGCAGGGCGTTTTCCCAAGGCTGGAGAACGTGGGTGCTTTCAAGAAGGTAT
CCATTGTGCCAACCCACGCCACGTGTGGATACCCAGGCCCCAGCACCTTTTGTCGTAGCGCCGT
GGCAGCTGAGCATGCGCAGTTGTGTGCCGAGAGGCTGTGTATCCAGGACTGCCCCTACCGCTCT
GCCTCTCCTCCCTATACCGCCCTCCTAGAAGGCCTCAGGAGCTGCATTCCTGCAGACCACGGTG
ATCTCCACCCTTACTCCAGAAGCAACTCCACGAGCTTCATATTCGGAAGTCACAAGAACTGCCC
CTCTCTACAGGCTCCGAGGCTGGCAGCAGAATTTACCTTAGCCGTGTGGTTGAAGCCCGAGCGA
GGCAGCACTATGTGTGTGCTAGAAAAGACAGCGGATGGGCAGATTGTGTTCAAAGTTACAATAT
CTGAGAGAGAGACCATGTTTTATTATCGCACAGTAAATGGTTTGCAGCCTCCAATAAAAGTAAT
GACACCAGGGAGAATTCTTATGAAGAAATGGATTCATCTCAGTGTGCAGGTGCATGAGACGGAA
GTCAGCTTCTTTGTGGATGGTTTGGAGGAGAACAGCACTGCATTCGATACAAGAACTCTCCGCG
ATTCAATCACGGACTCGGCCCCCAGCACTGTACTAATAGGACAGAGTTTAAACGGTTCAGAGCT
GTTTGTTGGAAGAATGCAAGATTTCCGATTGTACAACGTGTCACTTACAAACAGAGAGATTCTA
GAGCTCTTTTCTGGAGATCTCCCCCACTTGCACATCCAGTCACATTGCCGATGTCCAGGCAGCC
ATCCCCGTGTCCACCCCTCGGTTCAGCAGTATTGCATTCCCAATGGTGTGGAAGACACACTCCA
GCATCGAGTGTCACGGCTGAATCCTGAAGCCCACCCTCTCTCCTTCATCAATGATGACGACGTG
GCTACTTCATGGATCTCTCATGTGTTTACAGACATTACACAGCTCAATCAAGGAGTGGCAATCT
CTATAGACTTGGAAAATGGACAGTATCAGGTGTTTCAAATCACCATTCGGTTCTCCAGCCCACA
GCCTGTGGCGATGCGGATCCAGAGGAAGAAGGCAGACAAGTCTCTCTGGGAGGACTGGCAGTAT
TTTGCGAGAAATTGCAGTGTTTGGGGAATGAAAAACAATGGAGATCTGGAAAATCCCAATTCTG
TCAACTGTCTCCAGTTTCCTGATTTTATCCCGTTTTCCCACGGTAATGTCACCTTTGACCTCCT
AACATCTGGACAGAAGCATCGTCCTGGGGACTATGACTTTTACAACAGCTCATTGCTGCAAGAA
TTCATGACAGCCACTCAGATACGGCTGTACTTCCGAGGGCTGTTCTATCCCGCTTGGCACACTG
TTGACTCAAGACACAGATACTATGCAGTGGATGAGATCACCATCATTGGGAGATGTCAATGCCA
TGGCCATGCCGAGACCTGTGACAGAACCAGACGGCCTTACCAGTGTCTCTGCTCACCGCACAGC
TTCACTGAAGGGCCCCAGTGTGGTCGATGCTCCCCTCTTTATAATGACAAGCCTTTCCGCAGTG
GTAACAAAGTTCATGCATTCAACTGTAAGCCTTGTCAGTGCCATGGCCATGCCAGCAGCTGCCA
CTATGATGCTTCCATGGACCCATTTCCCCTGGAGTACAACAGAGGTGGCGGAGGAGTCTGTGAT
GACTGTCAGCACCACACAACAGGGAGAAACTGTGAGTCATGCCAGGACTACTTTTACCGACCCA
TTGGTGCCGATCCTGCTGACCCAGAGGTTTGCAAGCACTGTGACTGCAACAGGGACGGAACTAG
AAACGGCAGCCTCCTCTGTGACCTGGTTGGAGGCCAATGTGATTGTAAGAGACGTGTGTCTGGC
AGACGGTGCTTTCGGTGCCATATTGGGTTCTATGGCCTGCAGGCGCTGGATCCTGATGGCTGCC
GCCCCTGTGACTGTAATCCCTCTGGGACCGTGGATGGAGATATTACCTGTCACCACAATTCAGG
CCAGTGCTCATGCAAAGCGAACGTTATTGGGCTCCGATGCGATCGCTGCAGTTTCGGATTTAAG
TTTCTCCGGAGTTTGAACGCTGACGGATGTGAACCTTGCCATTGTAACCTCCATGGCTCGGTGA
ACCAACTCTGTGACCCACTCTCTGGGCAGTGTGTGTGCAAGAAGGAAGCTAAAGGACTTAGGTG
TGACGTTTGCAGAGAAAACTTTTATGGGCTGCCCTGGAGTGCTTGTGAGGTCTGTGATTGCAAC
AGGGCTGGCACCCAGGCTGGGACCGTGTGTGATGCTGAGACAGGGCAGTGCGTTTGTAAGCCCA
GTGTTGGAGGGAGACGATGTAGTGAGTGTAAAGAAGGGTACTTCAACCTACGTCAGAATGATTC
CCACCTCTGCTTACCTTGTAACTGTGAGAAGACCGGGACAGTAAACGGCTCTCTACTGTGTGAC
AAGTCAACTGGGCAGTGTCCCTGCAAATTAGGGGTAACTGGTCTACGCTGCCATCAGTGTGAGC
CTCACAGGTTCAATTTGACGGTGGACAACCTTCAAGGGTGTCAGGCGTGCGAGTGTGACTCCTT
GGGGACATTACCTGGAAGCACTTGTGACCCCGTCAGTGGCCAGTGCCTATGCCTACCTCATCGA
CAAGGAAGAAGGTGTGAGCGGTGTCAGCCAGGCTTTTACAGTTCTCCCGGCAATGCCACTGGCT
GTCTGCCATGCTCATGCCACACAGCTGGCGCTGTAAGCCACATCTGTAATAGTGTCACCGGGCA
GTGCTCTTGCCGCGATCCCTCCACCACTGGGCAGAGCTGTCACCAGTGTCAAGACCATTACTTT
GGATTTGATCCCAGGACCGGAAGATGCCAGCCTTGTCATTGTCATCTAGAAGGAGCCTTGAATG
AAACGTGTGATGTGGTCACAGGCCAGTGTTTCTGCAAAGAGTTTGTCACTGGCTCAAAATGTGA
CATTTGTGTTCCCGGAGCAAGCCACTTGGATGTCAACAATCTATTCGGCTGCAGCAAAACTCCA
TCCCAGCAACCTCCACCCAGAGGACGGGTTCAAAGCTCTTCTGCCATCAATCTCTCCTGGAGTC
CACCTGATTTTCCCAATGCACACTGGCTTACATACACTCTGTTCAGGGATGATTCCGAGATCTA
CACAACTGACGATCAGCACCCTTACTATACTCAGTACTTCTTGGACACTAGTCTGTCACCGCAC
ACAGCATATTCATATTACATAGAGACCTCCAATGTGCACAGTTCAACAAGGAGCATTCCTGTGA
TTTACAAGACAAAGCCAGAGGGCTCAGAAGGCCACTTGAACTTGACTCACATCATTCCTGTGGC
CTCAGACTCCATTACACTTGTCTGGACTGGACTCTCCAACCACTCTGGTCCTATAGAGAAGTAT
GTTTTATCATGCACACCTGTGGACCACACTGAGCCCTGTGTCTCTTATGAAGGTCCAGAGACCT
CAGCTACCATCAGGAATCTGGTTCCATTCACCCAGTACTGTTTCTCTGTCCAGGGCTGTACTAA
TGGGAGCTGTTTATATAGCTCACCTATTACAGTAACCACAGCCCAAGCGCCTCCCCAAAGGCAG
GAGCCACCTACAGTATGGAAAATCAGTCCCACAGAACTCAAAGTAGAATGGTCTCGGCCAGTGG
ATTCAAATGGTGTAATTATCAGGTATGAGTTATACATGAAGAGATGGCCGTCCACAGAGGAGAG
TCTCGTGTTTGAGAGCCATGGTTGGTTCCATTCTCACCCAGCCTCACCGTCAGCCAATCAGAGT
GAGAATGTGCTTCAGGATCCCCAAGTCAGCACAGTCCTCTCTGGCTTGGACCCACACACAGAGT
ATGCATTTAGGGTGTTGGCTGTGAATATGGCTGGCAGTGTGTCATCTGCCTGGGCTTCAGAAAG
AACAGGAGAATCAGCACCTGTGTTCATGGCTGCTCCTTCAGTCTCTCCACTCTCACCATACTCC
CTCAGTGTCTCCTGGGAGAAGCCAGCAGAAAACTTTACAAGAGGAGAGATTATAGGGTACAAGA
TCAGCATGGTTTCTGAACGTTCCCCTCAACGAGATGTTCCAGTCATGTGTTCAAAGCTGGTGCA
TTTTGCTGAGTCCCAAGACCAGTCTTACATCGTTCAGAGACTCAAGCCTTATAGGACCTACAGT
TTTACTGTCTCCCTCTGCTATTCAGTGGGCTGTGTAACCAGTGCTTTGGGAGAAGGACAAACGC
TAGCAGCAGCCCCTGCTCAGCTAAGGTCTCCCATGGTAACAGGAGTTACCAGCACTACAGTCCA
TATCAGGTGGCTTCCTCCTGCAGAAGTCAATGGCCCACCTCCCTTGTACCGTCTAGAAAGGAGG
GAGTCCTTTCTCCCAGCTGCCACGGCTGCGAGGACAAAGGGAACCCGCTTCATGGGAGACGGTT
ACTGCAGATTTCCCAGAACGGCTCACCCAGATTTTATAGGCATCAAGGCCAGCTTCTGGACAAG
GGTGCCTGAAGGGCTGATCCTCCTGGCACTGCACCCCGACAACCAGGAAGAGTATTTCGCCCTT
CAGTTGAAGAGTGGCCGTCCATACTTTCTTTACAACCCCCAGGGATCACTAGTGGAAGTTACCA
CAGCTGATGATCACAGTCAACAATACAGTGACGGACAGTGGCATGAAATCACAGCAATCAGACA
TCAGTCTTTTGGCCAGATCACTCTTGATGAGCAGTACACAGACTCCTCAGCTTCTCTGAACGGA
AGCTCCGTGACGGGAGGCTACACCAGACTGTTTGTAGGTGGGCTGCCACAAGGTCATACCATCC
TCCAGAAGAGGCCTGAGATAGTCCGAAGAGGCTTCGTGGGCTGCCTCAAGGATGTGTCCATCCT
GAAGGGTTCCAGCCCCTCTGGGACATGGCTACCTTTGGATTGGCAGAGCTCTGAGGAGCAGGTC
AATGTACATCACAGCTGGGAGGGGTGCCCCACCGACCTAGAAGAAGGAGTTCAGTTCCTGGGTG
CAGGATTTCTGGAGCTTCGTTCAGATACGTTTCATGCTGCAAAGGACTTTGAGATTTCCCTGAA
GTTTCAAACAGACCAACTAAATGGATTGCTTCTTTTCATTCACAATACAGAGGGTCTGGATTTT
CTTGCTATGGAGCTGAAGAGCGGGCTGCTGAGCTTCCAGTTAAATTCCAGCCGTATCTTGACAC
GCGTGGAGGTCAGGCTGGGACGGACCCACTGTGACGGAAAGTGGAATAGAGTCACTATCAGAAG
GGAGGGCTCCATGGTGTCAGTTGGTGTGAATGAACTTACGAAGAGCACCTCACGGGCCGGGGAC
CAGCCTCCGCTGCTGACTTCACCTGTCTATCTGGGTGGGATCCCACAGGAACTACAGGCCTCCT
ATAGACATTTGACTCTGGAGCAAGGGTTCCGTGGTTGCGTGAAGGAAGTTGCATTTACACGGGG
TGCTGTCGTTAACTTGGCATCTGTGTCCAGCCGTGCTGTCAGAGTCAATCAGGATGGATGCCTA
TCAAGTGACAGTACTGTTAACTGTGGGGGAAACGACTCCATCCTGGTTTATCGGGGAAGCCGGC
AGAGTGTTTACGAGAGCGGTCTCCAGCCCTTTACAGAATACCTGTATCGGGTCACAGCCTCACA
CAAAGGAGGTTCAGTATCCAGCGATTGGAGTCGGGGACGTACATTGGGCTCAGCTCCACACAGT
GTGCCAACTCCCTCAAGAGCCCAGAGCATAAATGGATACAGCGTTGAGGTGGCCTGGAATGAAC
CCGCTATGGTTAAGGGTGTCCTGGAGAAGTACATTCTGAAAGCCTACAGTGAAGACAGCGCCCA
ACCCCACATGCCCTCAGCCAGCACTGAGTTTAACAACACCGACATCCGCACAGGCATACTGACA
GGACTGCATCCCTTCCACAGCTACGCAGTAACCCTGACTGCTTGTTCTCGGGCGGGCTGCACCG
AGAGCTCACGTGCACTGAGCATCTCCACTCCACAAGAAGCACCCCAAGAGGTTCAGGCACCAGT
CGCCGAGGCCCTTCCCAATTCCCTGTCATTCTTCTGGAGTCCACCCAGACAAGCAAATGGAATT
ATTACACAGTACTCCCTATACATGGATGGGAGGCTGGTCTACACCGGCAAGGGACAGAACTACA
CAGTCACAGATTTAAGAGTATTCACGGCCTATGAGATTACAGTTGGTGCATGCACACGTGCGGG
GTGCACCAACAGCTCTCGAGTGATCCTGCACACAGCACAGCTGCCGCCAGAGCGAGTGGATCCC
CCAGTTTTGGCTATCCTGGATTCTAGGACTGTACACATACAATGGAAACAACCAAGGCAACTAA
ATGGAATCCTGGAGCGCTACATATTATATACATTGAATCCTACCCATAACTCCACAGTGTGGGA
TGTTGTCTACAACAGCACAGAAAACCTCCAGACCCACCTGCTCTACCACCTTTCCCCTGGGTGC
CTGTACCTCATCAAGCTGGGAGCGTGTACCGGCGGCGGCTGTACAACCAGTGAGCCTAGCCAAG
CCCTGATGGACGAGACTGTTCCAGAAGGAGTGCCAGCCCCCAGAGCCCACTCCCACTCACCAGA
CTCCTTTAACATCTCCTGGACAGAGCCTGGGCATCCGAATGGGGTGATCACAACATATGAGTTA
TATCTAGATGGTACTCTGATTCACAATTCTTCGGAACTGAGCTGCCATGCCTATGGATTTGACC
CTGGGAGCTTACACACCTTCCAAGTTCAAGCGTGCACAGCGAAGGGTTGTGCTCTTGGCCCATT
GGTAGAAAATCGGACTCTAGAAGCTCCTCCGGAAGGCACGGTCAATCTGTTTGTCAAACCTGAG
GGATCTCGGGAAGCTGCTGTGAGGTGGGATGCTCCTCCTCACCCTAATGGGCGCTTAACCTACT
CAGTCCTTATCACTGGAAATTTCTATGCAGATCAAGCAGGAGACAACTACACCCTTCTCAGCAG
CACAAAAACCGTGCACAGCAGCAAAGGAGACCGGCTCTGGGTGCTGGTGGACAGACTGGTTCCT
TGCTCGAATTACACTGTACAAGTGAATGCTTCCAATAGCCAAGGGAGCGTGCTCAGTGACCGCG
TCTCTGTTGAAATGCCTCCTGGCGCTCCAGATGGCCTGCTGTCTCCTAGGCTTGCAGCTGCCAC
TCCAACCAGTCTTCAGGTTGTCTGGTCTACACCAGCTCGCAACAATGCTCCGGGCTCTCCCAGA
TACCAGCTCCAGATGAGGCCTGACCCCTCCACCCGCGGCCTTCTAGAATTATTCCCCATTCCTT
CTGCATTATTAAGCTATGAAGTGACCGGTCTCCAGCCGTTCACAGTGTATGAGTTTCGGTTGGT
TGCCACCAATGGCTTTGGCAGTGCATACAGCGATTGGACTCCACTCATGACTACAGAAGACAAG
CCTGGACCTATGGACGCTCCTGTTCTAAATGTGAAAGCAGGGATGATGTCGGTTGCCTGGCGGA
AGCCTACAGAGTGCAATGGGGCCATCACCCATTATAACATTTACCAGCATGGCCGCCTCTACTT
AACAGTCTCTGGAGGGGTCACTAACTGCACTGTGGTCCATCTGCGGCCTCACACGGCCTATCAG
TTCCAGATAGAAGCCTGCTCCTCCAAAGGGTGCTCCATGTCACCAGCGTCTGAGACTGTGTGGA
CACTCCCAGGAACTCCAGAAGGTATCCCAGGCCCAGAGCTGTTGCCATACACTCCAACCAAGAT
CATAGTATCTTGGCAACCCCCGACGCACCTCGATGGCTTGGTTGAGAACATTACCATCGAGAGA
CGGGTCAAAGAGCAAGAGGAAGTTAGGAGCCTGGTGATCCTTCCAAGAAGTCAAGCCGTGAGGT
TTATAGATAATGATCCCGCCCTCCGCCCTTGGACACACTATGAATACCGGGTTCTGGGGAGCAC
TCTTAATGGAGGCACAAACAGCAGTGCTTGGGTGGAAGTGACCACAAGACCATCCCGTCCTTCC
GGAGTGCAGCCGCCCACGGTGCATGTGCTGGGACCGGATGCAGTCGAGGTCACTTGGAAAGCCC
CGCTAATCCGGAACGGAGACATAGTGAGCTATGAAATCCGAATGCCAGACCCGCTCATCGAAAT
AACCAATGTGACCTCGTTTGTGTTGAGTCATCTGGTCAAGCATCTGATTCCTTTCACTAACTAT
TCAGTCAGCATCGTTGCTTGCTCTGGAGGTCATGGGTACCTAGGAGGATGCACGGAGAGCCTAC
CTACCTTTGCAACTACCCACCCGGCCCTGCCTCAGGAACTGACCCCGCTGTCTATCAGTCTTCT
AGGCCAATCTTATGTTGGGATTTCTTGGCAGCCACCATCCAAACCAAATGGACCAAATTTGAGA
TACGAGCTTCTGAGACGTAAAATCCAGCAGCCACTTGCTTCAAATCCCCCAGAAGATTTAAATC
TGTGGCACAATATTTATTCAGGAACTCGGCGGTTTTACGAAGATAAGGGTCTTAGCAGGTTCAC
AACGTACGAATACAAGCTCTTCGTACACAACAGCCTGGGCTTTACACCGAGCCAGGAAGTGACA
GTCACCACCTTAGCTGGCTCTCCAGAGAGAGGAGCCACTGTCACCGCAAGCATCCTTAATCACA
CGGCCATAGACGTGAGATGGAAGAGACCAACATTTCAAGATCTGCAAGGTGATGTGGAATATTA
CACGCTGTTTTGGAGTTCTGGGACCTCGGTGGAGTCTCTGAAAATCTTCCCAGATGTAGACTTT
CACGTCATTGGCCACTTAGCCCCAAACGTGGAGTACCAGGTTTTCCTCTTGGTCTTCAATGGAG
TCCATGCAATCAACAGTACAGTAGTGCGAGTGACCACGTGGGAGGAAGAGCCTCGGGGCATGCG
TCCCCCAGAGGTTGTCATCATCAACAGTACAGCTGTACGTGTCATCTGGACATCGCCTTCAAAC
CCAAATGCCGTCATCACCGAGTCTTCTGTCTATGCAAATAACGAGCTCCACAAGGCTGGAGCGG
GCGCGCCGGGGTCGTTCACTCTGGAAGACCTGTCTCCCTTCACTATCTATGACATTCAGGTGGA
AGTCTGCACAAAAGACGCCTGTGTGAAAAGCAGTGGCACCCAAGTCAGCACAGCGGAAGATACT
CCAAGTGGCATTTCAATACCTATAATCCGTGATATTACTTCAAGATCCCTCCAAATAGATTGGA
CAGCACCAGGAAATCCAAATGGTATCATTCTTGGGTATGACGTTTTACGGAAAACATGGCGCCT
GTGCTCTGAAACCCAGAAGTTAACAGACAAACCCAGGGATGAGCTTTGCAAAGCAGTCAAGTGC
CAATACCCTGGAAATGTCTGTGGACACACTTGCTACTCTCCAGGAACTAAGGTATGTTGTGACG
GGCTTCTGTATGACCCTCAGCCTGGATACAGCTGCTGTGAGGAGAAATACATCGCACTCCTTCC
TAATTCCACTGGAGTTTGCTGTGGAGGGCGACAGCGGGAGGCACAGCCAGACCACCAGTGCTGC
TCCGGCCATTACATTAGAATCCTTCCAGGAGAGATATGCTGTCCCGATGAGAGGCACAACCGGG
TGTCTGTCGGCTTTGGTGATGCCTGCTGCGGCACAATGCCTTATGCCACCTCCGGGAGCCAGGT
GTGCTGTGCTGGGAAGCTCCAGGATGGCTACAGACGGCAGTGCTGTGGGGGAGAGATGGTGAGC
CAAGATTTCAAGTGCTGTGGTGGAGGAGAAGAGGGCATGGTATACAGTTCCCTCCCAGGAATGC
TGTGTTGCGGGCAGGATTATGTGAATATGTCGGATACCATATGCTGTTCAGCTTCCAGTGGAGA
CTCTAAAGCACACGTTAGAGGGAGTGACCCCATGCCAGTGAGATGCTGCCACACTGAACTTATT
CCAGAGAGCCAGCAATGCTGTGATGGAGTTGGATATAATCCCGTGAAATACGTTTGCTCTGATG
AGATTTCAGCGGGAATGGCGACGGAGGAAACCAGAGTATGTGCCACTGTCTGCCCAGCAACCAT
GAGAGCCACAGCACACTGTGGCCAGTGCGACTTCAACGCCACCACCCATATCTGCACGGTGTCG
AGAGGGCCTCTCAATCCCATAGGGAAGGAAACAGCAGAAGGACTGTGTTCCACAGCAGAGGAAA
TAGTTCATTCTGGAGATGAAAATACACGCTCTTTCATAGACACAGACCTGGAGCCCAGCACTGT
GTATGAATATAGGGTTTCTGTGTGGAACAGCTACGGGCGAGGATTCAGCCAGTCTGTTAGAGCC
AGCACAAGAGAAGATGTGCCTCAAGGCGTCACGGCCCCTAGGTGGGCTAGGACAGGCAATCATG
AAGATGTTATTTTCTTGACGTGGAAGGAACCCACACAGTCAAATGGTCCTATTACTCACTATAT
TCTCCTCCGAGACGGAAGGGAGCGCTTTCAGGGAGCAGCGCTGAGTTTCACGGACACACAGGGA
ATTCAGCCACTCCAGGAATATTCATACCAGCTGAAGGCTTGCACAGCCGCTGGCTGTGCCGACA
GTTGCAAGGTAGTCGCCACTGCCACCCGAGGAGTCCTGGAGAGTGTCCCACCACCAAACATCAC
AGCCCAGAGCCCGGAGACCCTGCACCTCAGCTGGAGTGTCCCTGAGAAAAGGAATGATGCCATT
AAAGAGTACCAGCTCTGGCTGGATGGGAAAGGGCTCATCTACACTGACACAAATGACAGGAGGC
AGCATACGGTCACAGGTCTCCAGCCACACACAAACTACAGCTTCACACTCTCGGCTTGTACATC
TGTCGGATGCACTTCCAGTGAGCCCTCTGTAGGTCAGACTCTGCAGGCTGCCCCTCAAGGAGTT
TGGGTGACACCGCGACACATTATCATCAATTCTACAACCGTGGAATTATATTGGAATCCTCCGG
AAAGGCCCAACGGTGTCATTTCTCAGTATCGGCTGAGACGTAATGGAAGCTTGCTTCTTGTGGG
TGGCAGAGATGATCAGAGTTTCACTGATAAAAACCTGGAGCCCAACAGCAGGTACATTTACACA
CTAGAAGCAAGAACTGGAGGTGGTAGCAGTTTGAGTGAGGAGTACCTTGTCCAGATGCCTATGT
GGACCCCAGAAGACGTCCATCCGCCGTGCAACGTCACCGTGCTGGGCTCCGATTCCATATTTGT
TGCATGGCCAGCACCAGGGATCCTGCTTCCCAAGATTCCAGTGGAGTACAGCATCTTACTCAGC
GGTGGGAACATGATGCTCTTAACTTTCTCGGTTGGACTCCGTCAGTCTGCATACCTGAAAAACC
TGGCCCCATTCACACAATATGAAATACGGATACAGGCCTGCCAAGAGGTAGGCTGTGGAGTTAG
CCCTGGGACACATGTCAGAACGCTTGAAGCAGCACCAGTGGGTCTAATGCCCCCTCTCCTGAAG
GCTCTGGGGTCACATTGCATAGAGGTGAAGTGGACGCCACCTACGAGACCCAATGGAATCATCA
CCAGCTATGTCATTCACAGGCGTCCTGCTGACACTGAAGAGGAGTCTCTGCTCTTTGTCTGGTC
AGAAGGAGCTCTTGAGTTCACTGATGACACAGACACTCTGCGGCCTTTTACCCTGTATGAGTAC
CGAGTGAGAGCCTGGAACTCCAAGGGTGTAGTGGACAGCCCGTGGTCATCAGTACAGACCTTGG
AAGCCCCACCTCAAGACCTCCCAGCACCATGGGTTCAAGTCACCAGTGCTCATTCAGTCCTGCT
AAACTGGACAGAGCCAGAGGCCCCCAATGGCCTTATCTCCCAGTACCATGTGATCTACCAAGAG
AGACCAGATGAGGCAGCGCCCGGCAGTTCTACCGTGCATGCGTTCACAGTGAAGGGATCAAGCC
GTCAAGCCCATCTCTTTGGCTTGGAACCATTCACGACGTACCACATCGGTGTGGCAGCTGTCAA
CCGTGCAGGGAAGGTGTCAAGCCCCTGGACCCTAATTAAGACTTTAGAGTCTGCCCCAAGCGGA
CTGATGAACTTCACAGCAGAGCAGAGAGAAGGCGGCCGGGCTCTGCTGCTGCAGTGGTCAGAGC
CAGTAAGGACCAACGGAGTGATCAAGGCATACAACGTCTTCAGCGATGGGCTCCCAGAGTACTC
AGGCCTGGGTCGACAGTTTCTCTTCCGGCGCTTGGCCCCCTTCACTCTCTACATCTTGACCCTG
GAGGCCTGCACAGCAGCGGGCTGTGCTCACTCGGTGCCCCAGACTCTCTGGACAGAGGAAGCTC
CTCCAGATTCTCAAATGGCTCCTACCATCCAGTCTGTGGAGCCCACCAGTGTAAGGCTGCACTG
GTCTCAGCCCGCTAACCCCAATGGGAAGATAATTCGTTATGAAGTGATCCGCAGACGCTTGCAG
GGAGAGGACTGGGGGAACAGGACAGTGCAGGCAGACGAGAACACTGTCTTCACGGAATACAACA
CAGAAGGGAATGGGTGGGTATGTACTGACACAGGCCTGCAGCCATGGGGGCTATACTCGTACAG
AATCTGCACTTGGAATTCCGCAGGGCACACCTGTAGCTCTTGGAGTGTGGTAAGAACATCGCAA
GCACCCCCAGACGGCCTCTCTCCACCAGAGGTATCCTACGTGTCTACGAGTCCCCTCCAACTGT
TGATTTCCTGGTTTGCACCCCGACACACTAATGGTGTCATCCAGTCCTACAGACTTCAAAGGAA
TGGAGTGTTCGCTGCTGCCAGTTTCAACTCCAGCACCTTCAGCTACACGGATGGCCAGCTGCTT
CCCTTTACAACTTACAGTTACGCTGTCCTTGCCTGCACGGGTGGTGGGTGCTGTACCAGTGAGC
CCACCAACATCACTACTCCTGAGGCATCTCCAGCAGGAGTCAGCCCTCCGGTTCTTTGGGCCAT
CGGTGCCCACCAGATAAATGTGTCTTGGTCCCCACCATCAGTCCCAAATGGAAAGATTGCTAAA
TATTTGCTTCACTGTGATGGCGAGGAGCACTTGGCTGGGCAGGACCTGTCCTTGCTGCTCTCCA
ACCTGCGGCCTTTCACCCAGTACAATGTCTCCCTGGTAGCCTGCACAAAGGGAGGGTGCACTGC
TAGTAGGGTCGCATCTGCCTGGACAATGGAGGCCCCACCAGAGGACATGGACCCGCCCACACTG
CACGTCATGGGCCCAGAATCAATAGAAATTACATGGGCACCTCCAAGAAACCCACATGGCCAGA
TCAGAAGTTATGAGCTTCGGAGAGATGGAGCCATTGTGTATATAGGCCTGGAAACTCGCTACCA
TGATTTTATCCTTACTCCAGGTGTCCAATATGGCTACACAGTGACTGCCACCAACAGCCGGGGC
AGTGTCTTGAGCCCACTTGTCAAGGGTCAAACCAGCCCCTCAGCTCCCTCAGGTTTACAGCCCC
CAAAGCTCCGTGCAGGGGAAGCTCTTGAGCTCTTAGTGAATTGGAACCCTCCAGTGAGGACAAA
CGGCAAGATCACCAACTACACGCTCTTCATCCGCGAGCTGTTGGAAGGAGAAATCAGAACTATG
TGTATTAACACAACACACAGTTCTTTTGGCACACGGTCACTCGCAGTAAAGCACCTGAAGCCGT
TTCACAGGTATGAAGTGCGTGTCCAAGCCTGCACGGCCCTCGGATGTACCTCCAGTGAGTGGAC
ACCTACCCAAACCTCAGAGATCCCACCTCTGCTGCAGCCAGCCCCACATCTGGAGGTGCAGACA
GCTGCAGGGGGATTTCAGCCCATAGTAGCCGTGTGGTGGGCAGGGCCCCTCCAGCCACACGGAA
AAATCGTACGCTTTGAATTGTACAGAAGACAGACCGCGTCCTGGCCTGGCACGTCCAGTCCGCT
GTTAATCTATAATGGCAGCTTAAGCTCCTTCACGGATCGAGAACTACTACCTTTCACGGAGTAC
GAATACCAGGTATGGGCAGTGAATTCTGCAGGCAAAGTGGCAAGTAACTGGACATGGTGTAGAA
CCGGACCTGCCCCGCCGGAAGGTCTCAAGGCGCCCACATTCCACACTGTCTCCTCCACCCAAGC
GGTGGTCAACATCAGTGCACCGTCGAAACCCAATGGGAACATCAGCCTCTTCAGGGTCTTCTCC
AACTCCAGCGGGACGCATGTCATGCTGTCTGAAGGCATGGCCACCCAGCAGACCCTTCATGACC
TGAGACCCTTCACCACATACGCCATTGGAGTTGAGGCTTGCACTTGTTTCAACTGCTGCAGCCG
AGGGCCGACAGCTGAGCTGAGGACCCATCCTGCCCCACCCTCAGGGCTGTCTCCTCCCCAGGTC
CAGACGCTGGGCTCAAGGATGGCCTCCTTCCAGTGGGCTCCCCCTCAGCTCCCCAATGGTGTCA
TTCACAGCTATGAACTGCAGCTGCACCGGGCTTGCCCTCCGGATTCAGCCCCACATTGCCCTCC
CAGTCCCACGGAGAGGAAGTACTGGGGCCCTGGGCACAGAGCCAGCCTGGCAGGGCTTCAGCCT
AATACGGCCTACGGGGTGCAAGTGGTGGCCCACAATGAAGCGGGCAGCACGGCTTCCGGGTGGA
CCAGCTTCCGCACCAAGAAGGAAATGCCTCAGTACCAAGCCCTGTTCTCAGTGGACAGCAATGC
ATCCACAGTGTGGGTAGACTGGAGTGGCACCTTTGTCCTGAATGGCCAGCTAAAGGAGTACGTG
GTCACCGACGGAGGACGGAGGGTGTACAGCGGCCTAGACACCACCCTCTACATACCAAGGACGG
TGGATAAAACTTTCTTCTTCCAGGTCACCTGCACGACAGACATTGGAAGTGTTAAGACTCCATT
GGTCCAGTATGATGCCACTACTGGATTTGGCCTGGTGCTGACAACTCCTGGAGGAAAGAAGGGA
GCAGGCACCAAAAGCACAGAGTTCTACAGTGAGCTGTGGTTCATTATGGTAATGGCCATACTGG
GCCTGATCTTGCTGGCCATTTTCCTGTCCTTAATTCTACAAAGAAAAATCCACAAGGAGCCATG
TATCAGAGAGAGACCTCCCTTGGTACCTCTTCAGAAACGAATGGCTCCACTGAGCGTCCACCCA
CCAGGGGAAACCCATGTGGGATTAGCCGACACCAGACTCCCTAGGTCTGGGACGCCTGTGAGTA
TTCGGAGCAGCCAAAGTGTGTCAGTACTGCGGATTCCAAGTCAAAGCCAACTGAGCCACGCCTA
CTCCCAGGGTTCTCTCCACCGCAGCGTCAGCCAGCTCATGGATAGTCCAGACAAGAAGGCCTTG
ACGGAGGACTCACTGTGGGAAACTATTATGGGCCACAGCAGTGGACTGTGTGTGGATGAAGAGG
AGCTTATGAACGCCATCAAGGGTTTCAGCTCCGTGACCAAGGAGCACACCGCCTTTACTGACAC
CCACCTGTAAACAACTGAGGTTAGAACATGGAACCCTGGGGTGCATGTTCTATACCCTCCTTTT
TTGCCCAGTTATCACATGTGATAAAAGCTGAAAAACACTGAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001289148	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL78289	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004992
GenBank Protein	Q8K3K1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001289148 ⟸ NM_001302219
- Peptide Label:	precursor
- UniProtKB:	Q8K3K1 (UniProtKB/Swiss-Prot), F1M2F9 (UniProtKB/Swiss-Prot), A0A5H1ZRU3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYYLALSSGFLGQAIKTSILAYLASVLLAASQGVFPRLENVGAFKKVSIVPTHATCGYPGPSTF CRSAVAAEHAQLCAERLCIQDCPYRSASPPYTALLEGLRSCIPADHGDLHPYSRSNSTSFIFGS HKNCPSLQAPRLAAEFTLAVWLKPERGSTMCVLEKTADGQIVFKVTISERETMFYYRTVNGLQP PIKVMTPGRILMKKWIHLSVQVHETEVSFFVDGLEENSTAFDTRTLRDSITDSAPSTVLIGQSL NGSELFVGRMQDFRLYNVSLTNREILELFSGDLPHLHIQSHCRCPGSHPRVHPSVQQYCIPNGV EDTLQHRVSRLNPEAHPLSFINDDDVATSWISHVFTDITQLNQGVAISIDLENGQYQVFQITIR FSSPQPVAMRIQRKKADKSLWEDWQYFARNCSVWGMKNNGDLENPNSVNCLQFPDFIPFSHGNV TFDLLTSGQKHRPGDYDFYNSSLLQEFMTATQIRLYFRGLFYPAWHTVDSRHRYYAVDEITIIG RCQCHGHAETCDRTRRPYQCLCSPHSFTEGPQCGRCSPLYNDKPFRSGNKVHAFNCKPCQCHGH ASSCHYDASMDPFPLEYNRGGGGVCDDCQHHTTGRNCESCQDYFYRPIGADPADPEVCKHCDCN RDGTRNGSLLCDLVGGQCDCKRRVSGRRCFRCHIGFYGLQALDPDGCRPCDCNPSGTVDGDITC HHNSGQCSCKANVIGLRCDRCSFGFKFLRSLNADGCEPCHCNLHGSVNQLCDPLSGQCVCKKEA KGLRCDVCRENFYGLPWSACEVCDCNRAGTQAGTVCDAETGQCVCKPSVGGRRCSECKEGYFNL RQNDSHLCLPCNCEKTGTVNGSLLCDKSTGQCPCKLGVTGLRCHQCEPHRFNLTVDNLQGCQAC ECDSLGTLPGSTCDPVSGQCLCLPHRQGRRCERCQPGFYSSPGNATGCLPCSCHTAGAVSHICN SVTGQCSCRDPSTTGQSCHQCQDHYFGFDPRTGRCQPCHCHLEGALNETCDVVTGQCFCKEFVT GSKCDICVPGASHLDVNNLFGCSKTPSQQPPPRGRVQSSSAINLSWSPPDFPNAHWLTYTLFRD DSEIYTTDDQHPYYTQYFLDTSLSPHTAYSYYIETSNVHSSTRSIPVIYKTKPEGSEGHLNLTH IIPVASDSITLVWTGLSNHSGPIEKYVLSCTPVDHTEPCVSYEGPETSATIRNLVPFTQYCFSV QGCTNGSCLYSSPITVTTAQAPPQRQEPPTVWKISPTELKVEWSRPVDSNGVIIRYELYMKRWP STEESLVFESHGWFHSHPASPSANQSENVLQDPQVSTVLSGLDPHTEYAFRVLAVNMAGSVSSA WASERTGESAPVFMAAPSVSPLSPYSLSVSWEKPAENFTRGEIIGYKISMVSERSPQRDVPVMC SKLVHFAESQDQSYIVQRLKPYRTYSFTVSLCYSVGCVTSALGEGQTLAAAPAQLRSPMVTGVT STTVHIRWLPPAEVNGPPPLYRLERRESFLPAATAARTKGTRFMGDGYCRFPRTAHPDFIGIKA SFWTRVPEGLILLALHPDNQEEYFALQLKSGRPYFLYNPQGSLVEVTTADDHSQQYSDGQWHEI TAIRHQSFGQITLDEQYTDSSASLNGSSVTGGYTRLFVGGLPQGHTILQKRPEIVRRGFVGCLK DVSILKGSSPSGTWLPLDWQSSEEQVNVHHSWEGCPTDLEEGVQFLGAGFLELRSDTFHAAKDF EISLKFQTDQLNGLLLFIHNTEGLDFLAMELKSGLLSFQLNSSRILTRVEVRLGRTHCDGKWNR VTIRREGSMVSVGVNELTKSTSRAGDQPPLLTSPVYLGGIPQELQASYRHLTLEQGFRGCVKEV AFTRGAVVNLASVSSRAVRVNQDGCLSSDSTVNCGGNDSILVYRGSRQSVYESGLQPFTEYLYR VTASHKGGSVSSDWSRGRTLGSAPHSVPTPSRAQSINGYSVEVAWNEPAMVKGVLEKYILKAYS EDSAQPHMPSASTEFNNTDIRTGILTGLHPFHSYAVTLTACSRAGCTESSRALSISTPQEAPQE VQAPVAEALPNSLSFFWSPPRQANGIITQYSLYMDGRLVYTGKGQNYTVTDLRVFTAYEITVGA CTRAGCTNSSRVILHTAQLPPERVDPPVLAILDSRTVHIQWKQPRQLNGILERYILYTLNPTHN STVWDVVYNSTENLQTHLLYHLSPGCLYLIKLGACTGGGCTTSEPSQALMDETVPEGVPAPRAH SHSPDSFNISWTEPGHPNGVITTYELYLDGTLIHNSSELSCHAYGFDPGSLHTFQVQACTAKGC ALGPLVENRTLEAPPEGTVNLFVKPEGSREAAVRWDAPPHPNGRLTYSVLITGNFYADQAGDNY TLLSSTKTVHSSKGDRLWVLVDRLVPCSNYTVQVNASNSQGSVLSDRVSVEMPPGAPDGLLSPR LAAATPTSLQVVWSTPARNNAPGSPRYQLQMRPDPSTRGLLELFPIPSALLSYEVTGLQPFTVY EFRLVATNGFGSAYSDWTPLMTTEDKPGPMDAPVLNVKAGMMSVAWRKPTECNGAITHYNIYQH GRLYLTVSGGVTNCTVVHLRPHTAYQFQIEACSSKGCSMSPASETVWTLPGTPEGIPGPELLPY TPTKIIVSWQPPTHLDGLVENITIERRVKEQEEVRSLVILPRSQAVRFIDNDPALRPWTHYEYR VLGSTLNGGTNSSAWVEVTTRPSRPSGVQPPTVHVLGPDAVEVTWKAPLIRNGDIVSYEIRMPD PLIEITNVTSFVLSHLVKHLIPFTNYSVSIVACSGGHGYLGGCTESLPTFATTHPALPQELTPL SISLLGQSYVGISWQPPSKPNGPNLRYELLRRKIQQPLASNPPEDLNLWHNIYSGTRRFYEDKG LSRFTTYEYKLFVHNSLGFTPSQEVTVTTLAGSPERGATVTASILNHTAIDVRWKRPTFQDLQG DVEYYTLFWSSGTSVESLKIFPDVDFHVIGHLAPNVEYQVFLLVFNGVHAINSTVVRVTTWEEE PRGMRPPEVVIINSTAVRVIWTSPSNPNAVITESSVYANNELHKAGAGAPGSFTLEDLSPFTIY DIQVEVCTKDACVKSSGTQVSTAEDTPSGISIPIIRDITSRSLQIDWTAPGNPNGIILGYDVLR KTWRLCSETQKLTDKPRDELCKAVKCQYPGNVCGHTCYSPGTKVCCDGLLYDPQPGYSCCEEKY IALLPNSTGVCCGGRQREAQPDHQCCSGHYIRILPGEICCPDERHNRVSVGFGDACCGTMPYAT SGSQVCCAGKLQDGYRRQCCGGEMVSQDFKCCGGGEEGMVYSSLPGMLCCGQDYVNMSDTICCS ASSGDSKAHVRGSDPMPVRCCHTELIPESQQCCDGVGYNPVKYVCSDEISAGMATEETRVCATV CPATMRATAHCGQCDFNATTHICTVSRGPLNPIGKETAEGLCSTAEEIVHSGDENTRSFIDTDL EPSTVYEYRVSVWNSYGRGFSQSVRASTREDVPQGVTAPRWARTGNHEDVIFLTWKEPTQSNGP ITHYILLRDGRERFQGAALSFTDTQGIQPLQEYSYQLKACTAAGCADSCKVVATATRGVLESVP PPNITAQSPETLHLSWSVPEKRNDAIKEYQLWLDGKGLIYTDTNDRRQHTVTGLQPHTNYSFTL SACTSVGCTSSEPSVGQTLQAAPQGVWVTPRHIIINSTTVELYWNPPERPNGVISQYRLRRNGS LLLVGGRDDQSFTDKNLEPNSRYIYTLEARTGGGSSLSEEYLVQMPMWTPEDVHPPCNVTVLGS DSIFVAWPAPGILLPKIPVEYSILLSGGNMMLLTFSVGLRQSAYLKNLAPFTQYEIRIQACQEV GCGVSPGTHVRTLEAAPVGLMPPLLKALGSHCIEVKWTPPTRPNGIITSYVIHRRPADTEEESL LFVWSEGALEFTDDTDTLRPFTLYEYRVRAWNSKGVVDSPWSSVQTLEAPPQDLPAPWVQVTSA HSVLLNWTEPEAPNGLISQYHVIYQERPDEAAPGSSTVHAFTVKGSSRQAHLFGLEPFTTYHIG VAAVNRAGKVSSPWTLIKTLESAPSGLMNFTAEQREGGRALLLQWSEPVRTNGVIKAYNVFSDG LPEYSGLGRQFLFRRLAPFTLYILTLEACTAAGCAHSVPQTLWTEEAPPDSQMAPTIQSVEPTS VRLHWSQPANPNGKIIRYEVIRRRLQGEDWGNRTVQADENTVFTEYNTEGNGWVCTDTGLQPWG LYSYRICTWNSAGHTCSSWSVVRTSQAPPDGLSPPEVSYVSTSPLQLLISWFAPRHTNGVIQSY RLQRNGVFAAASFNSSTFSYTDGQLLPFTTYSYAVLACTGGGCCTSEPTNITTPEASPAGVSPP VLWAIGAHQINVSWSPPSVPNGKIAKYLLHCDGEEHLAGQDLSLLLSNLRPFTQYNVSLVACTK GGCTASRVASAWTMEAPPEDMDPPTLHVMGPESIEITWAPPRNPHGQIRSYELRRDGAIVYIGL ETRYHDFILTPGVQYGYTVTATNSRGSVLSPLVKGQTSPSAPSGLQPPKLRAGEALELLVNWNP PVRTNGKITNYTLFIRELLEGEIRTMCINTTHSSFGTRSLAVKHLKPFHRYEVRVQACTALGCT SSEWTPTQTSEIPPLLQPAPHLEVQTAAGGFQPIVAVWWAGPLQPHGKIVRFELYRRQTASWPG TSSPLLIYNGSLSSFTDRELLPFTEYEYQVWAVNSAGKVASNWTWCRTGPAPPEGLKAPTFHTV SSTQAVVNISAPSKPNGNISLFRVFSNSSGTHVMLSEGMATQQTLHDLRPFTTYAIGVEACTCF NCCSRGPTAELRTHPAPPSGLSPPQVQTLGSRMASFQWAPPQLPNGVIHSYELQLHRACPPDSA PHCPPSPTERKYWGPGHRASLAGLQPNTAYGVQVVAHNEAGSTASGWTSFRTKKEMPQYQALFS VDSNASTVWVDWSGTFVLNGQLKEYVVTDGGRRVYSGLDTTLYIPRTVDKTFFFQVTCTTDIGS VKTPLVQYDATTGFGLVLTTPGGKKGAGTKSTEFYSELWFIMVMAILGLILLAIFLSLILQRKI HKEPCIRERPPLVPLQKRMAPLSVHPPGETHVGLADTRLPRSGTPVSIRSSQSVSVLRIPSQSQ LSHAYSQGSLHRSVSQLMDSPDKKALTEDSLWETIMGHSSGLCVDEEELMNAIKGFSSVTKEHT AFTDTHL hide sequence

Ensembl Acc Id:

ENSRNOP00000004992 ⟸ ENSRNOT00000004992

Protein Domains

Fibronectin type-III Laminin EGF-like Laminin G Laminin G-like Laminin N-terminal

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:628777	AgrOrtholog
BioCyc Gene	G2FUF-16924	BioCyc
Ensembl Genes	ENSRNOG00000003738	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000004992	ENTREZGENE
Gene3D-CATH	2.60.120.200	UniProtKB/Swiss-Prot
	2.60.40.10	UniProtKB/Swiss-Prot
	Galactose-binding domain-like	UniProtKB/Swiss-Prot
	Laminin	UniProtKB/Swiss-Prot
	Tie2 ligand-binding domain superfamily	UniProtKB/Swiss-Prot
InterPro	ConA-like_dom_sf	UniProtKB/Swiss-Prot
	FN3_dom	UniProtKB/Swiss-Prot
	FN3_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	LamG-like	UniProtKB/Swiss-Prot
	Laminin_EGF	UniProtKB/Swiss-Prot
	Laminin_G	UniProtKB/Swiss-Prot
	Laminin_N	UniProtKB/Swiss-Prot
	RTP_Phos/Ushers	UniProtKB/Swiss-Prot
NCBI Gene	Ush2a	ENTREZGENE
PANTHER	CYTOKINE RECEPTOR	UniProtKB/Swiss-Prot
	USHERIN	UniProtKB/Swiss-Prot
Pfam	fn3	UniProtKB/Swiss-Prot
	Laminin_EGF	UniProtKB/Swiss-Prot
	Laminin_G_2	UniProtKB/Swiss-Prot
	Laminin_G_3	UniProtKB/Swiss-Prot
	Laminin_N	UniProtKB/Swiss-Prot
PhenoGen	Ush2a	PhenoGen
PRINTS	EGFLAMININ	UniProtKB/Swiss-Prot
PROSITE	EGF_1	UniProtKB/Swiss-Prot
	EGF_LAM_1	UniProtKB/Swiss-Prot
	EGF_LAM_2	UniProtKB/Swiss-Prot
	FN3	UniProtKB/Swiss-Prot
	LAM_G_DOMAIN	UniProtKB/Swiss-Prot
	LAMININ_NTER	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000003738	RatGTEx
SMART	EGF_Lam	UniProtKB/Swiss-Prot
	FN3	UniProtKB/Swiss-Prot
	LamG	UniProtKB/Swiss-Prot
	LamGL	UniProtKB/Swiss-Prot
	LamNT	UniProtKB/Swiss-Prot
Superfamily-SCOP	EGF/Laminin	UniProtKB/Swiss-Prot
	SSF49265	UniProtKB/Swiss-Prot
	SSF49899	UniProtKB/Swiss-Prot
UniProt	A0A5H1ZRU3	ENTREZGENE, UniProtKB/TrEMBL
	F1M2F9	ENTREZGENE
	Q8K3K1	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	F1M2F9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Ush2a	usherin	LOC102554234	usherin-like	Data merged from RGD:7673532	737654	PROVISIONAL
2016-06-03	Ush2a	usherin	Ush2a	Usher syndrome 2A (autosomal recessive, mild)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-12-18	LOC102554234	usherin-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2012-10-02	Ush2a	Usher syndrome 2A (autosomal recessive, mild)	Ush2a	Usher syndrome 2A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-26	Ush2a	Usher syndrome 2A	Ush2a	Usher syndrome 2A homolog (human)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-12-16	Ush2a	Usher syndrome 2A homolog (human)	RGD1560269	similar to usherin isoform B	Data merged from RGD:1560269	737654	APPROVED
2008-12-15	Ush2a	Usher syndrome 2A homolog (human)	Ush2a	Usher syndrome 2A (autosomal recessive, mild) homolog (human)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1560269	similar to usherin isoform B	RGD1560269_predicted	similar to usherin isoform B (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1560269_predicted	similar to usherin isoform B (predicted)	LOC289369	similar to usherin isoform B	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC289369	similar to usherin isoform B			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-07-08	Ush2a	Usher syndrome 2A (autosomal recessive, mild) homolog (human)		Usher syndrome 2A (autosomal recessive, mild)	Name updated	1299863	APPROVED
2003-02-27	Ush2a	Usher syndrome 2A (autosomal recessive, mild)			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a leader sequence, an amino-terminal globular domain, 10 laminin epidermal growth factor domains, and four carboxy-terminal fibronectin type III motifs	634438

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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