Zdhhc2 (zDHHC palmitoyltransferase 2) - Rat Genome Database

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Gene: Zdhhc2 (zDHHC palmitoyltransferase 2) Rattus norvegicus
Analyze
Symbol: Zdhhc2
Name: zDHHC palmitoyltransferase 2 (Ensembl:zinc finger DHHC-type palmitoyltransferase 2)
RGD ID: 628681
Description: Predicted to enable protein homodimerization activity and protein-cysteine S-acyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation of protein localization to membrane; and regulation of synaptic plasticity. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acyltransferase ZDHHC2; DHHC-2; DHHC2; membrane-associated DHHC2 zinc finger protein; palmitoyltransferase ZDHHC2; rec; small rec; srec; zinc finger DHHC domain-containing protein 2; zinc finger DHHC-type palmitoyltransferase 2; zinc finger, DHHC domain containing 2; zinc finger, DHHC-type containing 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81658,511,931 - 58,581,530 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1658,511,934 - 58,581,516 (-)EnsemblGRCr8
mRatBN7.21651,808,465 - 51,878,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1651,808,468 - 51,878,060 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1657,140,319 - 57,202,110 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01660,529,020 - 60,597,093 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01655,774,273 - 55,836,067 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01654,932,546 - 55,002,322 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1654,934,056 - 55,002,322 (-)Ensemblrn6Rnor6.0
Rnor_5.01654,636,702 - 54,704,963 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41655,155,221 - 55,225,216 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1649,701,871 - 49,769,092 (-)NCBICelera
RGSC_v3.11655,155,532 - 55,225,274 (-)NCBI
Cytogenetic Map16q12.1NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fipronil  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
hydroquinone O-beta-D-glucopyranoside  (ISO)
indole-3-methanol  (EXP)
L-ascorbic acid  (EXP)
lead(0)  (ISO)
maneb  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
phenylephrine  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rimonabant  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triadimefon  (EXP)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP,ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Identification of PSD-95 palmitoylating enzymes. Fukata M, etal., Neuron 2004 Dec 16;44(6):987-96.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein. Jia L, etal., J Biol Chem. 2011 Apr 15;286(15):13695-703. doi: 10.1074/jbc.M110.193763. Epub 2011 Feb 22.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95. Noritake J, etal., J Cell Biol. 2009 Jul 13;186(1):147-60. doi: 10.1083/jcb.200903101.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Information Derived from GenBank Report RGD, Sept. 2003
10. The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150. Woolfrey KM, etal., J Neurosci. 2015 Jan 14;35(2):442-56. doi: 10.1523/JNEUROSCI.2243-14.2015.
Additional References at PubMed
PMID:16647879   PMID:18296695   PMID:18508921   PMID:21471008   PMID:22034844   PMID:23034182   PMID:23793055  


Genomics

Comparative Map Data
Zdhhc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81658,511,931 - 58,581,530 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1658,511,934 - 58,581,516 (-)EnsemblGRCr8
mRatBN7.21651,808,465 - 51,878,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1651,808,468 - 51,878,060 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1657,140,319 - 57,202,110 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01660,529,020 - 60,597,093 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01655,774,273 - 55,836,067 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01654,932,546 - 55,002,322 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1654,934,056 - 55,002,322 (-)Ensemblrn6Rnor6.0
Rnor_5.01654,636,702 - 54,704,963 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41655,155,221 - 55,225,216 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1649,701,871 - 49,769,092 (-)NCBICelera
RGSC_v3.11655,155,532 - 55,225,274 (-)NCBI
Cytogenetic Map16q12.1NCBI
ZDHHC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38817,156,482 - 17,224,799 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl817,155,974 - 17,224,799 (+)Ensemblhg38GRCh38
GRCh37817,013,991 - 17,082,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36817,058,402 - 17,124,612 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34817,058,401 - 17,124,612NCBI
Celera815,979,980 - 16,046,302 (+)NCBICelera
Cytogenetic Map8p22NCBI
HuRef815,558,794 - 15,625,120 (+)NCBIHuRef
CHM1_1817,214,983 - 17,281,694 (+)NCBICHM1_1
T2T-CHM13v2.0817,424,063 - 17,492,390 (+)NCBIT2T-CHM13v2.0
Zdhhc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39840,876,526 - 40,946,178 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl840,876,856 - 40,963,309 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38840,423,485 - 40,489,592 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl840,423,815 - 40,510,268 (+)Ensemblmm10GRCm38
MGSCv37841,509,169 - 41,570,196 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36841,922,632 - 41,983,659 (+)NCBIMGSCv36mm8
Celera843,078,568 - 43,134,878 (+)NCBICelera
Cytogenetic Map8A4NCBI
cM Map823.89NCBI
Zdhhc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955463315,531 - 345,716 (-)Ensembl
ChiLan1.0NW_004955463315,531 - 345,712 (-)NCBIChiLan1.0ChiLan1.0
ZDHHC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2735,616,352 - 35,682,529 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1811,350,918 - 11,417,072 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0816,368,954 - 16,437,623 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1813,343,011 - 13,380,803 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl813,343,011 - 13,380,803 (+)EnsemblpanPan2panpan1.1
ZDHHC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11640,496,469 - 40,551,979 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1640,506,524 - 40,543,360 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1640,983,307 - 41,049,439 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01642,539,281 - 42,605,661 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1642,539,277 - 42,604,615 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11640,632,635 - 40,698,974 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01641,175,866 - 41,242,231 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01641,369,230 - 41,435,644 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Zdhhc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494338,862,294 - 38,926,352 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365736,216,078 - 6,282,052 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365736,216,084 - 6,280,142 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZDHHC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl174,855,345 - 4,928,664 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1174,855,129 - 4,928,109 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2175,249,301 - 5,321,889 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZDHHC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1815,241,100 - 15,311,431 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl815,270,598 - 15,303,323 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605226,967,582 - 27,040,155 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zdhhc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476922,080,073 - 22,151,626 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476922,078,361 - 22,151,679 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Zdhhc2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11346,990,896 - 47,053,866 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Zdhhc2
544 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:518
Count of miRNA genes:251
Interacting mature miRNAs:321
Transcripts:ENSRNOT00000036092
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)164445512389455123Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)163692878281928782Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)164199206486992064Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16423421266955197Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162846870173468701Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164909919691442908Rat
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)163236104377361043Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)163105803976058039Rat
1298529Arunc1Aerobic running capacity QTL 14exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)163439829479398294Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683908666195506Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683908666195506Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)163188527176885271Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)164445512389455123Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683908666195506Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161773081872536785Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)161590580260905802Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683908666195506Rat

Markers in Region
BE114229  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21651,808,520 - 51,808,676 (+)MAPPERmRatBN7.2
Rnor_6.01654,932,602 - 54,932,757NCBIRnor6.0
Rnor_5.01654,635,248 - 54,635,403UniSTSRnor5.0
Celera1649,700,417 - 49,700,572UniSTS
RH 3.4 Map16524.5UniSTS
Cytogenetic Map16q12.1UniSTS
AU047323  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21651,816,210 - 51,816,410 (+)MAPPERmRatBN7.2
Rnor_6.01654,940,292 - 54,940,489NCBIRnor6.0
Rnor_5.01654,642,938 - 54,643,135UniSTSRnor5.0
RGSC_v3.41655,161,440 - 55,161,637UniSTSRGSC3.4
Celera1649,708,107 - 49,708,304UniSTS
Cytogenetic Map16q12.1UniSTS
BM388073  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21651,809,478 - 51,809,638 (+)MAPPERmRatBN7.2
Rnor_6.01654,933,560 - 54,933,719NCBIRnor6.0
Rnor_5.01654,636,206 - 54,636,365UniSTSRnor5.0
RGSC_v3.41655,154,724 - 55,154,883UniSTSRGSC3.4
Celera1649,701,375 - 49,701,534UniSTS
RH 3.4 Map16520.51UniSTS
Cytogenetic Map16q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 355 192 11 141 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000036092   ⟹   ENSRNOP00000033473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1658,520,055 - 58,581,516 (-)Ensembl
mRatBN7.2 Ensembl1651,816,591 - 51,878,060 (-)Ensembl
Rnor_6.0 Ensembl1654,934,056 - 55,002,322 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119635   ⟹   ENSRNOP00000084203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1658,511,934 - 58,581,315 (-)Ensembl
mRatBN7.2 Ensembl1651,808,468 - 51,877,859 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000128608   ⟹   ENSRNOP00000099943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1658,511,934 - 58,581,315 (-)Ensembl
RefSeq Acc Id: NM_145096   ⟹   NP_659564
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,513,441 - 58,581,516 (-)NCBI
mRatBN7.21651,809,975 - 51,878,060 (-)NCBI
Rnor_6.01654,934,056 - 55,002,322 (-)NCBI
Rnor_5.01654,636,702 - 54,704,963 (-)NCBI
RGSC_v3.41655,155,221 - 55,225,216 (-)RGD
Celera1649,701,871 - 49,769,092 (-)RGD
Sequence:
RefSeq Acc Id: XM_008771288   ⟹   XP_008769510
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,511,931 - 58,581,530 (-)NCBI
mRatBN7.21651,808,465 - 51,878,043 (-)NCBI
Rnor_6.01654,932,546 - 55,002,236 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094197   ⟹   XP_038950125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81658,511,931 - 58,555,727 (-)NCBI
mRatBN7.21651,808,465 - 51,852,269 (-)NCBI
RefSeq Acc Id: NP_659564   ⟸   NM_145096
- UniProtKB: Q9JKR5 (UniProtKB/Swiss-Prot),   A0P8F1 (UniProtKB/Swiss-Prot),   Q2TGK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008769510   ⟸   XM_008771288
- Peptide Label: isoform X1
- UniProtKB: Q2TGK4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000033473   ⟸   ENSRNOT00000036092
RefSeq Acc Id: XP_038950125   ⟸   XM_039094197
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000084203   ⟸   ENSRNOT00000119635
Ensembl Acc Id: ENSRNOP00000099943   ⟸   ENSRNOT00000128608
Protein Domains
DHHC   Palmitoyltransferase DHHC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JKR5-F1-model_v2 AlphaFold Q9JKR5 1-366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700124
Promoter ID:EPDNEW_R10648
Type:initiation region
Name:Zdhhc2_1
Description:zinc finger, DHHC-type containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01655,002,322 - 55,002,382EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628681 AgrOrtholog
BioCyc Gene G2FUF-11242 BioCyc
Ensembl Genes ENSRNOG00000022686 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000119635 ENTREZGENE
  ENSRNOT00000119635.1 UniProtKB/Swiss-Prot
  ENSRNOT00000128608 ENTREZGENE
InterPro Palmitoyltrfase_DHHC UniProtKB/Swiss-Prot
  PFA4/ZDH16/20/ERF2-like UniProtKB/Swiss-Prot
KEGG Report rno:246326 UniProtKB/Swiss-Prot
NCBI Gene 246326 ENTREZGENE
PANTHER PALMITOYLTRANSFERASE ZDHHC16 UniProtKB/Swiss-Prot
Pfam DHHC UniProtKB/Swiss-Prot
PhenoGen Zdhhc2 PhenoGen
PROSITE DHHC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000022686 RatGTEx
UniProt A0A8L2QHK7_RAT UniProtKB/TrEMBL
  A0ABK0LER8_RAT UniProtKB/TrEMBL
  A0P8F1 ENTREZGENE
  A6JPV8_RAT UniProtKB/TrEMBL
  Q2TGK4 ENTREZGENE, UniProtKB/TrEMBL
  Q9JKR5 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0P8F1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Zdhhc2  zDHHC palmitoyltransferase 2  Zdhhc2  zinc finger DHHC-type palmitoyltransferase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-09-13 Zdhhc2  zinc finger DHHC-type palmitoyltransferase 2  Zdhhc2  zinc finger, DHHC-type containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-17 Zdhhc2  zinc finger, DHHC-type containing 2  Zdhhc2  zinc finger, DHHC domain containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Zdhhc2  zinc finger, DHHC domain containing 2      Symbol and Name status set to approved 625702 APPROVED
2003-02-27 Zdhhc2  zinc finger, DHHC domain containing 2      Symbol and Name status set to provisional 70820 PROVISIONAL