Rnf34 (ring finger protein 34) - Rat Genome Database

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Gene: Rnf34 (ring finger protein 34) Rattus norvegicus
Analyze
Symbol: Rnf34
Name: ring finger protein 34
RGD ID: 628636
Description: Enables ubiquitin protein ligase activity. Involved in regulation of postsynaptic neurotransmitter receptor internalization. Is active in GABA-ergic synapse; postsynaptic specialization; and presynapse. Orthologous to human RNF34 (ring finger protein 34); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase RNF34; MGC93980; Momo; ring finger protein 34, E3 ubiquitin protein ligase; RING finger protein MOMO; RING-type E3 ubiquitin transferase RNF34
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,364,461 - 39,385,391 (-)NCBIGRCr8
mRatBN7.21233,703,655 - 33,724,606 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,703,673 - 33,724,586 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1234,882,808 - 34,902,193 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,494,172 - 35,513,557 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,545,596 - 34,566,473 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,164,290 - 39,185,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,164,290 - 39,185,168 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,057,289 - 41,078,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,805,137 - 34,826,016 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11234,668,524 - 34,689,404 (-)NCBI
Celera1235,382,479 - 35,403,370 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO,ISS)
cytosol  (IEA)
endomembrane system  (IEA)
GABA-ergic synapse  (IDA,IMP)
nuclear body  (ISO)
nuclear speck  (IEA)
nucleoplasm  (ISO)
nucleus  (ISO,ISS)
plasma membrane  (IBA,IEA,ISO,ISS)
postsynaptic specialization  (IDA)
presynapse  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A palmitoylated RING finger ubiquitin ligase and its homologue in the brain membranes. Araki K, etal., J Neurochem 2003 Aug;86(3):749-62.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Ring finger protein 34 (RNF34) interacts with and promotes gamma-aminobutyric acid type-A receptor degradation via ubiquitination of the gamma2 subunit. Jin H, etal., J Biol Chem. 2014 Oct 17;289(42):29420-36. doi: 10.1074/jbc.M114.603068. Epub 2014 Sep 5.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15069192   PMID:15489334   PMID:17121812   PMID:18382127   PMID:22064484   PMID:25012219   PMID:28902127  


Genomics

Comparative Map Data
Rnf34
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,364,461 - 39,385,391 (-)NCBIGRCr8
mRatBN7.21233,703,655 - 33,724,606 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,703,673 - 33,724,586 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1234,882,808 - 34,902,193 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,494,172 - 35,513,557 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,545,596 - 34,566,473 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,164,290 - 39,185,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,164,290 - 39,185,168 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,057,289 - 41,078,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,805,137 - 34,826,016 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11234,668,524 - 34,689,404 (-)NCBI
Celera1235,382,479 - 35,403,370 (-)NCBICelera
Cytogenetic Map12q16NCBI
RNF34
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812121,400,118 - 121,424,348 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12121,400,083 - 121,430,623 (+)EnsemblGRCh38hg38GRCh38
GRCh3712121,837,921 - 121,862,151 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612120,322,285 - 120,346,538 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412120,300,621 - 120,324,875NCBI
Celera12121,475,573 - 121,499,826 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12118,847,675 - 118,871,945 (+)NCBIHuRef
CHM1_112121,806,339 - 121,830,742 (+)NCBICHM1_1
T2T-CHM13v2.012121,366,860 - 121,415,781 (+)NCBIT2T-CHM13v2.0
Rnf34
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395122,988,270 - 123,007,008 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5122,988,111 - 123,009,354 (+)EnsemblGRCm39 Ensembl
GRCm385122,850,112 - 122,868,945 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5122,850,048 - 122,871,291 (+)EnsemblGRCm38mm10GRCm38
MGSCv375123,300,197 - 123,318,954 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365123,110,805 - 123,129,562 (+)NCBIMGSCv36mm8
Celera5119,936,301 - 119,955,549 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.62NCBI
Rnf34
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,891,546 - 6,905,139 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,889,112 - 6,905,139 (-)NCBIChiLan1.0ChiLan1.0
RNF34
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210129,466,369 - 129,509,485 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112129,462,743 - 129,505,859 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,998,436 - 119,022,823 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112122,373,125 - 122,396,579 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12122,373,172 - 122,402,693 (+)Ensemblpanpan1.1panPan2
RNF34
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,746,460 - 7,767,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,744,924 - 7,767,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha267,905,034 - 7,932,810 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,997,181 - 8,024,945 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,001,662 - 8,024,896 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1267,928,632 - 7,956,393 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,015,897 - 8,043,664 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,971,921 - 7,999,702 (-)NCBIUU_Cfam_GSD_1.0
Rnf34
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118156,560,433 - 156,577,926 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365582,901,512 - 2,919,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365582,901,386 - 2,918,976 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF34
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1431,206,674 - 31,229,484 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11431,202,030 - 31,229,529 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RNF34
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111116,777,294 - 116,800,816 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11116,777,419 - 116,800,035 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037128,233,321 - 128,257,267 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf34
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474721,904,667 - 21,920,778 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474721,904,652 - 21,920,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf34
83 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:258
Count of miRNA genes:184
Interacting mature miRNAs:203
Transcripts:ENSRNOT00000001799
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)122806443340130419Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)122860752637691617Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)122806455740218380Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961088935682913Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat

Markers in Region
RH128319  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21233,703,873 - 33,704,064 (+)MAPPERmRatBN7.2
Rnor_6.01239,164,491 - 39,164,681NCBIRnor6.0
Rnor_5.01241,057,490 - 41,057,680UniSTSRnor5.0
RGSC_v3.41234,805,338 - 34,805,528UniSTSRGSC3.4
Celera1235,382,680 - 35,382,870UniSTS
Cytogenetic Map12q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000001799   ⟹   ENSRNOP00000001799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1233,703,676 - 33,724,569 (-)Ensembl
Rnor_6.0 Ensembl1239,164,290 - 39,185,168 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103449   ⟹   ENSRNOP00000080689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1233,703,673 - 33,724,586 (-)Ensembl
RefSeq Acc Id: NM_001004075   ⟹   NP_001004075
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,340 (-)NCBI
mRatBN7.21233,703,673 - 33,724,554 (-)NCBI
Rnor_6.01239,164,290 - 39,185,168 (-)NCBI
Rnor_5.01241,057,289 - 41,078,204 (-)NCBI
RGSC_v3.41234,805,137 - 34,826,016 (-)RGD
Celera1235,382,479 - 35,403,370 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249360   ⟹   XP_006249422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,384,210 (-)NCBI
mRatBN7.21233,703,756 - 33,722,284 (-)NCBI
Rnor_6.01239,164,290 - 39,182,431 (-)NCBI
Rnor_5.01241,057,289 - 41,078,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249361   ⟹   XP_006249423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,391 (-)NCBI
mRatBN7.21233,703,655 - 33,724,606 (-)NCBI
Rnor_6.01239,164,290 - 39,185,209 (-)NCBI
Rnor_5.01241,057,289 - 41,078,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063271103   ⟹   XP_063127173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,391 (-)NCBI
RefSeq Acc Id: XM_063271104   ⟹   XP_063127174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,391 (-)NCBI
RefSeq Acc Id: NP_001004075   ⟸   NM_001004075
- UniProtKB: Q8CIP0 (UniProtKB/Swiss-Prot),   Q6AYH3 (UniProtKB/Swiss-Prot),   A6J174 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249423   ⟸   XM_006249361
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006249422   ⟸   XM_006249360
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G4W4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001799   ⟸   ENSRNOT00000001799
Ensembl Acc Id: ENSRNOP00000080689   ⟸   ENSRNOT00000103449
RefSeq Acc Id: XP_063127174   ⟸   XM_063271104
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G4W4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063127173   ⟸   XM_063271103
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G4W4 (UniProtKB/TrEMBL)
Protein Domains
RING-type   SAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYH3-F1-model_v2 AlphaFold Q6AYH3 1-381 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698638
Promoter ID:EPDNEW_R9161
Type:initiation region
Name:Rnf34_1
Description:ring finger protein 34
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01239,185,158 - 39,185,218EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628636 AgrOrtholog
BioCyc Gene G2FUF-19277 BioCyc
Ensembl Genes ENSRNOG00000001331 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001799.6 UniProtKB/Swiss-Prot
  ENSRNOT00000103449.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.720.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7115027 IMAGE-MGC_LOAD
InterPro CARP1_2_FYVE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CARP1_FYVE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RING-FYVE_E3_ubiquitin-ligase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:282845 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93980 IMAGE-MGC_LOAD
NCBI Gene 282845 ENTREZGENE
PANTHER CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE RNF34 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FYVE_CARP1-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf34 PhenoGen
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001331 RatGTEx
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF68906 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6G4W4 ENTREZGENE, UniProtKB/TrEMBL
  A6J174 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYH3 ENTREZGENE
  Q8CIP0 ENTREZGENE
  RNF34_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q8CIP0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 Rnf34  ring finger protein 34  Rnf34  ring finger protein 34, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-15 Rnf34  ring finger protein 34, E3 ubiquitin protein ligase  Rnf34  ring finger protein 34  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rnf34  ring finger protein 34      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Rnf34  ring finger protein 34      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains two zinc finger motifs and a RING finger domain 708308
gene_expression expressed in brain 708308