Rnf34 (ring finger protein 34) - Rat Genome Database

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Gene: Rnf34 (ring finger protein 34) Rattus norvegicus
Analyze
Symbol: Rnf34
Name: ring finger protein 34
RGD ID: 628636
Description: Enables ubiquitin protein ligase activity. Involved in regulation of postsynaptic neurotransmitter receptor internalization. Is active in GABA-ergic synapse; postsynaptic specialization; and presynapse. Orthologous to human RNF34 (ring finger protein 34); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E3 ubiquitin-protein ligase RNF34; MGC93980; Momo; ring finger protein 34, E3 ubiquitin protein ligase; RING finger protein MOMO; RING-type E3 ubiquitin transferase RNF34
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,364,461 - 39,385,391 (-)NCBIGRCr8
mRatBN7.21233,703,655 - 33,724,606 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,703,673 - 33,724,586 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1234,882,808 - 34,902,193 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,494,172 - 35,513,557 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,545,596 - 34,566,473 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,164,290 - 39,185,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,164,290 - 39,185,168 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,057,289 - 41,078,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,805,137 - 34,826,016 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11234,668,524 - 34,689,404 (-)NCBI
Celera1235,382,479 - 35,403,370 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
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Original Reference(s)
Rnf34Ratshort chain acyl-CoA dehydrogenase deficiency  ISORNF34 (Homo sapiens)8554872ClinVar Annotator: match by term: Deficiency of butyryl-CoA dehydrogenaseClinVarPMID:28492532
Object Symbol
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Original Reference(s)
Rnf34RatColonic Neoplasms  ISORNF34 (Homo sapiens)11554173CTD Direct Evidence: therapeuticCTDPMID:16270526

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Original Reference(s)
Rnf34Rat(+)-catechin multiple interactionsISORNF34 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of RNF34 mRNACTDPMID:24763279
Rnf34Rat(-)-demecolcine increases expressionISORNF34 (Homo sapiens)6480464Demecolcine results in increased expression of RNF34 mRNACTDPMID:23649840
Rnf34Rat1,2-dimethylhydrazine multiple interactionsISORnf34 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RNF34 mRNACTDPMID:22206623
Rnf34Rat1,2-dimethylhydrazine decreases expressionISORnf34 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of RNF34 mRNACTDPMID:22206623
Rnf34Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORnf34 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RNF34 mRNACTDPMID:21570461
Rnf34Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of RNF34 mRNACTDPMID:21346803
Rnf34Rat5-fluorouracil multiple interactionsISORNF34 (Homo sapiens)6480464[Fluorouracil co-treated with RNF34 protein] results in increased expression of BCL2 mRNA more ...CTDPMID:16080519 more ...
Rnf34Rat5-fluorouracil decreases response to substanceISORNF34 (Homo sapiens)6480464RNF34 protein results in decreased susceptibility to Fluorouracil and RNF34 protein results in decreased susceptibility to Fluorouracil analogCTDPMID:16080519 more ...
Rnf34Rataflatoxin B1 increases expressionISORnf34 (Mus musculus)6480464Aflatoxin B1 results in increased expression of RNF34 mRNACTDPMID:19770486
Rnf34Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of RNF34 mRNACTDPMID:16483693
Rnf34Ratarsane affects methylationISORNF34 (Homo sapiens)6480464Arsenic affects the methylation of RNF34 geneCTDPMID:25304211
Rnf34Ratarsenic atom affects methylationISORNF34 (Homo sapiens)6480464Arsenic affects the methylation of RNF34 geneCTDPMID:25304211
Rnf34Ratarsenous acid increases expressionISORNF34 (Homo sapiens)6480464Arsenic Trioxide results in increased expression of RNF34 mRNACTDPMID:20458559
Rnf34Ratbenzo[a]pyrene multiple interactionsISORnf34 (Mus musculus)6480464AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RNF34 mRNA]CTDPMID:22228805
Rnf34Ratbeta-lapachone decreases expressionISORNF34 (Homo sapiens)6480464beta-lapachone results in decreased expression of RNF34 mRNACTDPMID:38218311
Rnf34Ratbis(2-ethylhexyl) phthalate increases expressionISORnf34 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of RNF34 mRNACTDPMID:34319233
Rnf34Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of RNF34 mRNACTDPMID:25181051
Rnf34Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of RNF34 geneCTDPMID:28505145
Rnf34Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of RNF34 mRNACTDPMID:30816183 and PMID:32528016
Rnf34Ratcadmium dichloride decreases expressionEXP 6480464Cadmium Chloride results in decreased expression of RNF34 mRNACTDPMID:33453195

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Biological Process
1 to 20 of 36 rows

  
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Original Reference(s)
Rnf34Ratapoptotic process involved_inIEAUniProtKB-KW:KW-00531600115GO_REF:0000043UniProtGO_REF:0000043
Rnf34Ratcellular response to cold involved_inIEAUniProtKB:Q99KR6 and ensembl:ENSMUSP000000314341600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratcellular response to cold involved_inISORnf34 (Mus musculus)1624291 PMID:22064484RGDPMID:22064484
Rnf34Ratnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors involved_inISORNF34 (Homo sapiens)1624291 PMID:15069192RGDPMID:15069192
Rnf34Ratnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors involved_inIBAPANTHER:PTN001028628 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rnf34Ratnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors involved_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors involved_inISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratnegative regulation of signal transduction by p53 class mediator involved_inISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratnegative regulation of signal transduction by p53 class mediator involved_inISORNF34 (Homo sapiens)1624291 PMID:17121812RGDPMID:17121812
Rnf34Ratnegative regulation of signal transduction by p53 class mediator involved_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratnucleotide-binding domain, leucine rich repeat containing receptor signaling pathway involved_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratnucleotide-binding domain, leucine rich repeat containing receptor signaling pathway involved_inISORNF34 (Homo sapiens)1624291 PMID:25012219RGDPMID:25012219
Rnf34Ratnucleotide-binding domain, leucine rich repeat containing receptor signaling pathway involved_inISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inISORNF34 (Homo sapiens)1624291 PMID:15069192 more ...RGDPMID:15069192 more ...
Rnf34Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIBAFB:FBgn0033783 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rnf34Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:Q99KR6 and ensembl:ENSMUSP000000314341600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inISORnf34 (Mus musculus)1624291 PMID:22064484RGDPMID:22064484
Rnf34Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratprotein K48-linked ubiquitination involved_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
1 to 20 of 28 rows

  
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Original Reference(s)
Rnf34Ratcytoplasm located_inISORNF34 (Homo sapiens)1624291 PMID:15069192RGDPMID:15069192
Rnf34Ratcytoplasm located_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratcytoplasm is_active_inIBAMGI:1914588 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rnf34Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Rnf34Ratcytoplasm located_inISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Rnf34Ratendomembrane system located_inIEAUniProtKB-SubCell:SL-01471600115GO_REF:0000044UniProtGO_REF:0000044
Rnf34RatGABA-ergic synapse is_active_inIDA 10047328PMID:25193658SynGO 
Rnf34RatGABA-ergic synapse is_active_inIMP 10047328PMID:25193658SynGO 
Rnf34Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Rnf34Ratnuclear body located_inISORNF34 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Rnf34Ratnuclear body located_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratnuclear speck located_inIEAUniProtKB-SubCell:SL-01861600115GO_REF:0000044UniProtGO_REF:0000044
Rnf34Ratnucleoplasm located_inISORNF34 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Rnf34Ratnucleoplasm located_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratnucleus located_inISORNF34 (Homo sapiens)1624291 PMID:22064484RGDPMID:22064484
Rnf34Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Rnf34Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Rnf34Ratnucleus located_inISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratnucleus located_inIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
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Original Reference(s)
Rnf34Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Rnf34Ratp53 binding enablesISORNF34 (Homo sapiens)1624291UniProtKB:P04637 more ...RGDPMID:17121812 and PMID:18382127
Rnf34Ratp53 binding enablesIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratphosphatidylinositol phosphate binding enablesIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratphosphatidylinositol phosphate binding enablesISORNF34 (Homo sapiens)1624291 PMID:15069192RGDPMID:15069192
Rnf34Ratphosphatidylinositol phosphate binding enablesISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratprotein binding enablesISORNF34 (Homo sapiens)1624291UniProtKB:G5E9A7 more ...RGDPMID:15069192 more ...
Rnf34Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
Rnf34Ratubiquitin protein ligase activity enablesIDA 10047328PMID:25193658CACAO 
Rnf34Ratubiquitin protein ligase activity enablesIBAFB:FBgn0033783 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rnf34Ratubiquitin protein ligase activity enablesISORNF34 (Homo sapiens)1624291 PMID:15069192 more ...RGDPMID:15069192 more ...
Rnf34Ratubiquitin protein ligase activity enablesIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratubiquitin protein ligase activity enablesISSUniProtKB:Q969K31600115GO_REF:0000024UniProtGO_REF:0000024
Rnf34Ratubiquitin protein ligase binding enablesISORNF34 (Homo sapiens)1624291UniProtKB:Q00987 and PMID:18382127RGDPMID:18382127
Rnf34Ratubiquitin protein ligase binding enablesIEAUniProtKB:Q969K3 and ensembl:ENSP000003551371600115GO_REF:0000107EnsemblGO_REF:0000107
Rnf34Ratubiquitin-protein transferase activity  IDA 708308 RGD 
Rnf34Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
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#
Reference Title
Reference Citation
1. A palmitoylated RING finger ubiquitin ligase and its homologue in the brain membranes. Araki K, etal., J Neurochem 2003 Aug;86(3):749-62.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Ring finger protein 34 (RNF34) interacts with and promotes gamma-aminobutyric acid type-A receptor degradation via ubiquitination of the gamma2 subunit. Jin H, etal., J Biol Chem. 2014 Oct 17;289(42):29420-36. doi: 10.1074/jbc.M114.603068. Epub 2014 Sep 5.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:15069192   PMID:15489334   PMID:17121812   PMID:18382127   PMID:22064484   PMID:25012219   PMID:28902127  



Rnf34
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81239,364,461 - 39,385,391 (-)NCBIGRCr8
mRatBN7.21233,703,655 - 33,724,606 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,703,673 - 33,724,586 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1234,882,808 - 34,902,193 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01235,494,172 - 35,513,557 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01234,545,596 - 34,566,473 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01239,164,290 - 39,185,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1239,164,290 - 39,185,168 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01241,057,289 - 41,078,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,805,137 - 34,826,016 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11234,668,524 - 34,689,404 (-)NCBI
Celera1235,382,479 - 35,403,370 (-)NCBICelera
Cytogenetic Map12q16NCBI
RNF34
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812121,400,118 - 121,424,348 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12121,400,083 - 121,430,623 (+)EnsemblGRCh38hg38GRCh38
GRCh3712121,837,921 - 121,862,151 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612120,322,285 - 120,346,538 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412120,300,621 - 120,324,875NCBI
Celera12121,475,573 - 121,499,826 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12118,847,675 - 118,871,945 (+)NCBIHuRef
CHM1_112121,806,339 - 121,830,742 (+)NCBICHM1_1
T2T-CHM13v2.012121,366,860 - 121,415,781 (+)NCBIT2T-CHM13v2.0
Rnf34
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395122,988,270 - 123,007,008 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5122,988,111 - 123,009,354 (+)EnsemblGRCm39 Ensembl
GRCm385122,850,112 - 122,868,945 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5122,850,048 - 122,871,291 (+)EnsemblGRCm38mm10GRCm38
MGSCv375123,300,197 - 123,318,954 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365123,110,805 - 123,129,562 (+)NCBIMGSCv36mm8
Celera5119,936,301 - 119,955,549 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map562.62NCBI
Rnf34
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,891,546 - 6,905,139 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,889,112 - 6,905,139 (-)NCBIChiLan1.0ChiLan1.0
RNF34
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210129,466,369 - 129,509,485 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112129,462,743 - 129,505,859 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012118,998,436 - 119,022,823 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112122,373,125 - 122,396,579 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12122,373,172 - 122,402,693 (+)Ensemblpanpan1.1panPan2
RNF34
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,746,460 - 7,767,967 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl267,744,924 - 7,767,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha267,905,034 - 7,932,810 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,997,181 - 8,024,945 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,001,662 - 8,024,896 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1267,928,632 - 7,956,393 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0268,015,897 - 8,043,664 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,971,921 - 7,999,702 (-)NCBIUU_Cfam_GSD_1.0
Rnf34
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118156,560,433 - 156,577,926 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365582,901,512 - 2,919,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365582,901,386 - 2,918,976 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF34
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1431,206,674 - 31,229,484 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11431,202,030 - 31,229,529 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RNF34
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111116,777,294 - 116,800,816 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11116,777,419 - 116,800,035 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037128,233,321 - 128,257,267 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf34
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474721,904,667 - 21,920,778 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474721,904,652 - 21,920,579 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rnf34
83 total Variants

Predicted Target Of
Summary Value
Count of predictions:258
Count of miRNA genes:184
Interacting mature miRNAs:203
Transcripts:ENSRNOT00000001799
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
8693635Alc28Alcohol consumption QTL 282.70.439drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)122308134044726024Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat

1 to 10 of 51 rows
RH128319  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21233,703,873 - 33,704,064 (+)MAPPERmRatBN7.2
Rnor_6.01239,164,491 - 39,164,681NCBIRnor6.0
Rnor_5.01241,057,490 - 41,057,680UniSTSRnor5.0
RGSC_v3.41234,805,338 - 34,805,528UniSTSRGSC3.4
Celera1235,382,680 - 35,382,870UniSTS
Cytogenetic Map12q16UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000001799   ⟹   ENSRNOP00000001799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1233,703,676 - 33,724,569 (-)Ensembl
Rnor_6.0 Ensembl1239,164,290 - 39,185,168 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103449   ⟹   ENSRNOP00000080689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1233,703,673 - 33,724,586 (-)Ensembl
RefSeq Acc Id: NM_001004075   ⟹   NP_001004075
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,340 (-)NCBI
mRatBN7.21233,703,673 - 33,724,554 (-)NCBI
Rnor_6.01239,164,290 - 39,185,168 (-)NCBI
Rnor_5.01241,057,289 - 41,078,204 (-)NCBI
RGSC_v3.41234,805,137 - 34,826,016 (-)RGD
Celera1235,382,479 - 35,403,370 (-)RGD
Sequence:
RefSeq Acc Id: XM_006249360   ⟹   XP_006249422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,384,210 (-)NCBI
mRatBN7.21233,703,756 - 33,722,284 (-)NCBI
Rnor_6.01239,164,290 - 39,182,431 (-)NCBI
Rnor_5.01241,057,289 - 41,078,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006249361   ⟹   XP_006249423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,391 (-)NCBI
mRatBN7.21233,703,655 - 33,724,606 (-)NCBI
Rnor_6.01239,164,290 - 39,185,209 (-)NCBI
Rnor_5.01241,057,289 - 41,078,204 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063271103   ⟹   XP_063127173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,391 (-)NCBI
RefSeq Acc Id: XM_063271104   ⟹   XP_063127174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81239,364,461 - 39,385,391 (-)NCBI
RefSeq Acc Id: NP_001004075   ⟸   NM_001004075
- UniProtKB: Q8CIP0 (UniProtKB/Swiss-Prot),   Q6AYH3 (UniProtKB/Swiss-Prot),   A6J174 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006249423   ⟸   XM_006249361
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006249422   ⟸   XM_006249360
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G4W4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001799   ⟸   ENSRNOT00000001799
Ensembl Acc Id: ENSRNOP00000080689   ⟸   ENSRNOT00000103449
RING-type   SAP

Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYH3-F1-model_v2 AlphaFold Q6AYH3 1-381 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13698638
Promoter ID:EPDNEW_R9161
Type:initiation region
Name:Rnf34_1
Description:ring finger protein 34
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01239,185,158 - 39,185,218EPDNEW


1 to 38 of 38 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-19277 BioCyc
Ensembl Genes ENSRNOG00000001331 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001799 ENTREZGENE
  ENSRNOT00000001799.6 UniProtKB/Swiss-Prot
  ENSRNOT00000103449 ENTREZGENE
Gene3D-CATH 1.10.720.140 UniProtKB/Swiss-Prot
  1.10.720.30 UniProtKB/Swiss-Prot
  3.30.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7115027 IMAGE-MGC_LOAD
InterPro CARP1_2_FYVE UniProtKB/Swiss-Prot
  CARP1_FYVE UniProtKB/Swiss-Prot
  RING-FYVE_E3_ubiquitin-ligase UniProtKB/Swiss-Prot
  RNF34L-like_HeH UniProtKB/Swiss-Prot
  SAP_dom_sf UniProtKB/Swiss-Prot
  Znf_FYVE_PHD UniProtKB/Swiss-Prot
  Znf_RING UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
KEGG Report rno:282845 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93980 IMAGE-MGC_LOAD
NCBI Gene 282845 ENTREZGENE
PANTHER CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING UniProtKB/Swiss-Prot
  E3 UBIQUITIN-PROTEIN LIGASE RNF34 UniProtKB/Swiss-Prot
Pfam FYVE_CARP1-2 UniProtKB/Swiss-Prot
  RNF34L-like_3rd UniProtKB/Swiss-Prot
  zf-C3HC4_3 UniProtKB/Swiss-Prot
PhenoGen Rnf34 PhenoGen
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001331 RatGTEx
SMART RING UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF57903 UniProtKB/Swiss-Prot
  SSF68906 UniProtKB/Swiss-Prot
UniProt A0A8I6G4W4 ENTREZGENE, UniProtKB/TrEMBL
  A6J174 ENTREZGENE, UniProtKB/TrEMBL
  Q6AYH3 ENTREZGENE
  Q8CIP0 ENTREZGENE
  RNF34_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q8CIP0 UniProtKB/Swiss-Prot
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 Rnf34  ring finger protein 34  Rnf34  ring finger protein 34, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-15 Rnf34  ring finger protein 34, E3 ubiquitin protein ligase  Rnf34  ring finger protein 34  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rnf34  ring finger protein 34      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Rnf34  ring finger protein 34      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_domains contains two zinc finger motifs and a RING finger domain 708308
gene_expression expressed in brain 708308