Sec14l2 (SEC14-like lipid binding 2) - Rat Genome Database

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Gene: Sec14l2 (SEC14-like lipid binding 2) Rattus norvegicus
Analyze
Symbol: Sec14l2
Name: SEC14-like lipid binding 2
RGD ID: 621779
Description: Enables enzyme activator activity and transferase activity, transferring alkyl or aryl (other than methyl) groups. Involved in positive regulation of cholesterol biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Orthologous to human SEC14L2 (SEC14 like lipid binding 2); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alpha-tocopherol-associated protein; SEC14 (S. cerevisiae)-like 2; SEC14-like 2 (S. cerevisiae); SEC14-like protein 2; Spf; squalene transfer protein; supernatant protein factor; TAP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81483,197,384 - 83,222,059 (-)NCBIGRCr8
mRatBN7.21478,973,805 - 78,998,480 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,973,808 - 78,993,788 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1483,414,439 - 83,434,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,654,518 - 84,674,478 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01481,100,444 - 81,120,373 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01484,335,594 - 84,360,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1484,335,597 - 84,355,528 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01485,017,259 - 85,041,827 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,728,484 - 84,748,418 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,747,628 - 84,767,563 (-)NCBI
Celera1477,884,808 - 77,904,737 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(R)-linalyl acetate  (ISO)
1,8-cineole  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butoxyethanol  (ISO)
2-ethoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-terpineol  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-terpineol  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
flutamide  (EXP,ISO)
gamma-terpinene  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
inulin  (ISO)
ivermectin  (ISO)
limonene  (ISO)
linalool  (ISO)
linalyl acetate  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sotorasib  (ISO)
tea tree oil  (ISO)
terbufos  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trametinib  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
cytosol  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis. Shibata N, etal., Proc Natl Acad Sci U S A 2001 Feb 27;98(5):2244-9.
Additional References at PubMed
PMID:7364757   PMID:10829015   PMID:11444841   PMID:12477932   PMID:15581604   PMID:15680919   PMID:17092608   PMID:22871113   PMID:23533145   PMID:34008672  


Genomics

Comparative Map Data
Sec14l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81483,197,384 - 83,222,059 (-)NCBIGRCr8
mRatBN7.21478,973,805 - 78,998,480 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,973,808 - 78,993,788 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1483,414,439 - 83,434,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,654,518 - 84,674,478 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01481,100,444 - 81,120,373 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01484,335,594 - 84,360,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1484,335,597 - 84,355,528 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01485,017,259 - 85,041,827 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,728,484 - 84,748,418 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,747,628 - 84,767,563 (-)NCBI
Celera1477,884,808 - 77,904,737 (-)NCBICelera
Cytogenetic Map14q21NCBI
SEC14L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,397,018 - 30,425,303 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,396,941 - 30,425,303 (+)EnsemblGRCh38hg38GRCh38
GRCh372230,793,007 - 30,821,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,122,933 - 29,149,828 (+)NCBINCBI36Build 36hg18NCBI36
Build 342229,117,486 - 29,144,382NCBI
Celera2214,592,619 - 14,620,968 (+)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2213,754,252 - 13,782,494 (+)NCBIHuRef
CHM1_12230,752,095 - 30,780,850 (+)NCBICHM1_1
T2T-CHM13v2.02230,860,348 - 30,888,644 (+)NCBIT2T-CHM13v2.0
Sec14l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,047,039 - 4,068,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl114,047,039 - 4,073,415 (-)EnsemblGRCm39 Ensembl
GRCm38114,097,039 - 4,118,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,097,039 - 4,123,415 (-)EnsemblGRCm38mm10GRCm38
MGSCv37113,997,042 - 4,018,732 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,997,042 - 4,018,732 (-)NCBIMGSCv36mm8
Celera114,592,969 - 4,615,073 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.87NCBI
Sec14l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554554,636,709 - 4,660,058 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554554,637,062 - 4,660,064 (+)NCBIChiLan1.0ChiLan1.0
SEC14L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22340,363,958 - 40,390,569 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,062,594 - 43,090,650 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02211,432,608 - 11,460,973 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,234,162 - 29,261,937 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,234,162 - 29,261,937 (+)Ensemblpanpan1.1panPan2
LOC477539
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12623,542,555 - 23,563,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,413,626 - 23,433,383 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02623,926,643 - 23,946,387 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2623,926,486 - 23,946,800 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12623,628,117 - 23,647,869 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02623,890,926 - 23,910,663 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02623,951,320 - 23,971,099 (+)NCBIUU_Cfam_GSD_1.0
Sec14l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118116,457,964 - 116,479,252 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936904253,436 - 276,897 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936904254,979 - 276,267 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC14L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,370,055 - 47,392,499 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,369,663 - 47,391,335 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,454,593 - 50,475,848 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEC14L2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,276,712 - 13,302,737 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1913,276,913 - 13,305,003 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045112,841,789 - 112,869,976 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec14l2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247476,719,498 - 6,742,794 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247476,719,549 - 6,742,794 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sec14l2
78 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:575
Count of miRNA genes:257
Interacting mature miRNAs:309
Transcripts:ENSRNOT00000006542
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat

Markers in Region
BF387395  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21478,977,787 - 78,977,985 (+)MAPPERmRatBN7.2
Rnor_6.01484,339,577 - 84,339,774NCBIRnor6.0
Rnor_5.01485,021,242 - 85,021,439UniSTSRnor5.0
RGSC_v3.41484,732,467 - 84,732,664UniSTSRGSC3.4
Celera1477,888,791 - 77,888,988UniSTS
RH 3.4 Map14544.5UniSTS
Cytogenetic Map14q21UniSTS
RH139394  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21478,973,916 - 78,974,059 (+)MAPPERmRatBN7.2
Rnor_6.01484,335,706 - 84,335,848NCBIRnor6.0
Rnor_5.01485,017,371 - 85,017,513UniSTSRnor5.0
RGSC_v3.41484,728,596 - 84,728,738UniSTSRGSC3.4
Celera1477,884,920 - 77,885,062UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000006542   ⟹   ENSRNOP00000006542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1478,973,808 - 78,993,788 (-)Ensembl
Rnor_6.0 Ensembl1484,335,597 - 84,355,528 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095157   ⟹   ENSRNOP00000090393
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1478,978,352 - 78,993,788 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098251   ⟹   ENSRNOP00000079897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1478,973,808 - 78,991,813 (-)Ensembl
RefSeq Acc Id: NM_053801   ⟹   NP_446253
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81483,197,384 - 83,217,317 (-)NCBI
mRatBN7.21478,973,805 - 78,993,740 (-)NCBI
Rnor_6.01484,335,594 - 84,355,528 (-)NCBI
Rnor_5.01485,017,259 - 85,041,827 (-)NCBI
RGSC_v3.41484,728,484 - 84,748,418 (-)RGD
Celera1477,884,808 - 77,904,737 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251154   ⟹   XP_006251216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81483,197,384 - 83,222,059 (-)NCBI
mRatBN7.21478,973,805 - 78,998,480 (-)NCBI
Rnor_6.01484,335,594 - 84,360,354 (-)NCBI
Rnor_5.01485,017,259 - 85,041,827 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039091558   ⟹   XP_038947486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81483,197,384 - 83,218,258 (-)NCBI
mRatBN7.21478,973,805 - 78,994,692 (-)NCBI
RefSeq Acc Id: NP_446253   ⟸   NM_053801
- UniProtKB: Q5EBD0 (UniProtKB/TrEMBL),   F7F3C3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251216   ⟸   XM_006251154
- Peptide Label: isoform X1
- UniProtKB: F7F3C3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006542   ⟸   ENSRNOT00000006542
RefSeq Acc Id: XP_038947486   ⟸   XM_039091558
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ADK3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079897   ⟸   ENSRNOT00000098251
Ensembl Acc Id: ENSRNOP00000090393   ⟸   ENSRNOT00000095157
Protein Domains
CRAL-TRIO   GOLD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99MS0-F1-model_v2 AlphaFold Q99MS0 1-403 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699439
Promoter ID:EPDNEW_R9963
Type:initiation region
Name:Sec14l2_1
Description:SEC14-like lipid binding 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01484,355,534 - 84,355,594EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621779 AgrOrtholog
BioCyc Gene G2FUF-15186 BioCyc
Ensembl Genes ENSRNOG00000004672 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055029740 UniProtKB/Swiss-Prot
  ENSRNOG00060022120 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006542.5 UniProtKB/TrEMBL
  ENSRNOT00000095157.1 UniProtKB/TrEMBL
  ENSRNOT00000098251.1 UniProtKB/TrEMBL
  ENSRNOT00055051587 UniProtKB/Swiss-Prot
  ENSRNOT00060038673 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.525.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GOLD domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7322689 IMAGE-MGC_LOAD
InterPro CRAL-TRIO_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRAL-TRIO_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRAL/TRIO_N_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRAL/TRIO_N_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GOLD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GOLD_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC14/CRAL-TRIO_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116486 UniProtKB/TrEMBL
MGC_CLONE MGC:108628 IMAGE-MGC_LOAD
NCBI Gene 116486 ENTREZGENE
PANTHER SEC14 RELATED PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC14-LIKE PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CRAL_TRIO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CRAL_TRIO_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sec14l2 PhenoGen
PRINTS CRETINALDHBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CRAL_TRIO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GOLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004672 RatGTEx
  ENSRNOG00055029740 RatGTEx
  ENSRNOG00060022120 RatGTEx
SMART CRAL_TRIO_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF101576 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF46938 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52087 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6ADK3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5V9_RAT UniProtKB/TrEMBL
  A6IKE7_RAT UniProtKB/TrEMBL
  F7F3C3 ENTREZGENE, UniProtKB/TrEMBL
  Q5EBD0 ENTREZGENE, UniProtKB/TrEMBL
  Q99MS0 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-30 Sec14l2  SEC14-like lipid binding 2  Sec14l2  SEC14-like 2 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Sec14l2  SEC14-like 2 (S. cerevisiae)    SEC14 (S. cerevisiae)-like 2  Name updated 1299863 APPROVED
2002-08-07 Sec14l2  SEC14 (S. cerevisiae)-like 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed at high levels in liver and small intestine 727312
gene_product member of a family of cytosolic lipid-binding transfer proteins 727312