Mipep (mitochondrial intermediate peptidase) - Rat Genome Database

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Gene: Mipep (mitochondrial intermediate peptidase) Rattus norvegicus
Analyze
Symbol: Mipep
Name: mitochondrial intermediate peptidase
RGD ID: 621680
Description: Enables endopeptidase activity. Predicted to be involved in peptide metabolic process and protein processing involved in protein targeting to mitochondrion. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 31. Orthologous to human MIPEP (mitochondrial intermediate peptidase); PARTICIPATES IN presequence pathway of mitochondrial protein import; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MIP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81539,102,301 - 39,227,915 (+)NCBIGRCr8
mRatBN7.21534,926,198 - 35,051,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,926,207 - 35,051,727 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1536,787,866 - 36,893,767 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,938,483 - 38,044,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01536,387,341 - 36,492,974 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01541,084,180 - 41,192,621 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1541,084,206 - 41,190,005 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01544,896,328 - 45,002,041 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41539,871,329 - 39,990,743 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11539,887,028 - 40,006,443 (+)NCBI
Celera1534,627,565 - 34,731,545 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
Brodifacoum  (EXP)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
finasteride  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
glafenine  (EXP)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
methapyrilene  (EXP,ISO)
methidathion  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
nitrofen  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phytoestrogen  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
Tanshinone I  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrial matrix  (IDA)
mitochondrion  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue. Isaya G, etal., Proc Natl Acad Sci U S A 1992 Sep 1;89(17):8317-21.
3. Rat liver mitochondrial intermediate peptidase (MIP): purification and initial characterization. Kalousek F, etal., EMBO J. 1992 Aug;11(8):2803-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Processing of mitochondrial presequences. Mossmann D, etal., Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):1098-106. doi: 10.1016/j.bbagrm.2011.11.007. Epub 2011 Dec 7.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:14651853   PMID:18614015  


Genomics

Comparative Map Data
Mipep
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81539,102,301 - 39,227,915 (+)NCBIGRCr8
mRatBN7.21534,926,198 - 35,051,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,926,207 - 35,051,727 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1536,787,866 - 36,893,767 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,938,483 - 38,044,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01536,387,341 - 36,492,974 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01541,084,180 - 41,192,621 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1541,084,206 - 41,190,005 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01544,896,328 - 45,002,041 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41539,871,329 - 39,990,743 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11539,887,028 - 40,006,443 (+)NCBI
Celera1534,627,565 - 34,731,545 (+)NCBICelera
Cytogenetic Map15p12NCBI
MIPEP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381323,730,189 - 23,889,400 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1323,730,189 - 23,889,400 (-)EnsemblGRCh38hg38GRCh38
GRCh371324,304,328 - 24,463,539 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361323,202,328 - 23,361,559 (-)NCBINCBI36Build 36hg18NCBI36
Build 341323,202,328 - 23,361,533NCBI
Celera135,366,999 - 5,526,241 (-)NCBICelera
Cytogenetic Map13q12.12NCBI
HuRef135,115,419 - 5,274,678 (-)NCBIHuRef
CHM1_11324,272,481 - 24,431,743 (-)NCBICHM1_1
T2T-CHM13v2.01322,936,639 - 23,095,878 (-)NCBIT2T-CHM13v2.0
Mipep
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391461,022,011 - 61,142,930 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1461,022,022 - 61,142,927 (+)EnsemblGRCm39 Ensembl
GRCm381460,784,562 - 60,905,481 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1460,784,573 - 60,905,478 (+)EnsemblGRCm38mm10GRCm38
MGSCv371461,403,403 - 61,522,450 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361459,738,692 - 59,859,588 (+)NCBIMGSCv36mm8
Celera1458,563,091 - 58,670,430 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1431.95NCBI
Mipep
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554974,062,677 - 4,196,889 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554974,065,090 - 4,196,999 (-)NCBIChiLan1.0ChiLan1.0
MIPEP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21423,344,721 - 23,512,342 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11314,451,978 - 14,624,321 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0135,040,237 - 5,207,674 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11323,334,266 - 23,500,582 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1323,334,267 - 23,500,582 (-)Ensemblpanpan1.1panPan2
MIPEP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12514,755,474 - 14,930,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2514,753,596 - 14,930,369 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2514,833,115 - 15,007,225 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02514,886,171 - 15,060,823 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2514,886,180 - 15,062,683 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12514,767,513 - 14,942,058 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02514,770,383 - 14,944,826 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02514,818,700 - 14,993,399 (+)NCBIUU_Cfam_GSD_1.0
Mipep
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945116,980,530 - 117,124,623 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366881,592,821 - 1,737,282 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366881,592,810 - 1,736,896 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIPEP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl112,670,000 - 2,790,727 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1112,675,604 - 2,790,760 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2112,039,126 - 2,144,089 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIPEP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.133,578,057 - 3,726,783 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl33,578,193 - 3,726,746 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605740,804,644 - 41,015,711 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mipep
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477613,880,417 - 14,037,610 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477613,877,579 - 14,034,875 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mipep
549 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:52
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000018845
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

Markers in Region
D15Rat86  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,924,510 - 34,924,750 (+)MAPPERmRatBN7.2
Rnor_6.01541,082,490 - 41,082,727NCBIRnor6.0
Rnor_5.01544,894,605 - 44,894,842UniSTSRnor5.0
RGSC_v3.41539,869,605 - 39,869,843RGDRGSC3.4
RGSC_v3.41539,869,606 - 39,869,843UniSTSRGSC3.4
RGSC_v3.11539,885,276 - 39,885,610RGD
Celera1534,625,858 - 34,626,095UniSTS
SHRSP x BN Map1527.8098RGD
SHRSP x BN Map1527.8098UniSTS
Cytogenetic Map15p12UniSTS
BE117302  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,999,339 - 34,999,499 (+)MAPPERmRatBN7.2
Rnor_6.01541,157,052 - 41,157,211NCBIRnor6.0
Rnor_5.01544,969,174 - 44,969,333UniSTSRnor5.0
RGSC_v3.41539,956,612 - 39,956,771UniSTSRGSC3.4
Celera1534,698,673 - 34,698,832UniSTS
RH 3.4 Map15229.5UniSTS
Cytogenetic Map15p12UniSTS
AU048566  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21535,003,975 - 35,004,185 (+)MAPPERmRatBN7.2
Rnor_6.01541,161,688 - 41,161,897NCBIRnor6.0
Rnor_5.01544,973,810 - 44,974,019UniSTSRnor5.0
RGSC_v3.41539,961,248 - 39,961,457UniSTSRGSC3.4
Celera1534,703,309 - 34,703,518UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR459947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM061883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM065705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM100741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM117087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FN806671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB965597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HD023007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M96633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018845   ⟹   ENSRNOP00000018845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1534,926,223 - 35,032,245 (+)Ensembl
Rnor_6.0 Ensembl1541,084,213 - 41,189,894 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085785   ⟹   ENSRNOP00000073167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1534,926,207 - 35,051,727 (+)Ensembl
Rnor_6.0 Ensembl1541,084,206 - 41,190,005 (+)Ensembl
RefSeq Acc Id: NM_031052   ⟹   NP_112314
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,327 - 39,208,348 (+)NCBI
mRatBN7.21534,926,220 - 35,032,246 (+)NCBI
Rnor_6.01541,084,197 - 41,189,926 (+)NCBI
Rnor_5.01544,896,328 - 45,002,041 (+)NCBI
RGSC_v3.41539,871,329 - 39,990,743 (+)RGD
Celera1534,627,565 - 34,731,545 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770779   ⟹   XP_008769001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,301 - 39,208,348 (+)NCBI
mRatBN7.21534,926,198 - 35,034,941 (+)NCBI
Rnor_6.01541,084,180 - 41,192,621 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093685   ⟹   XP_038949613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,301 - 39,227,915 (+)NCBI
mRatBN7.21534,926,198 - 35,051,722 (+)NCBI
RefSeq Acc Id: XM_063274693   ⟹   XP_063130763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,301 - 39,143,871 (+)NCBI
RefSeq Acc Id: NP_112314   ⟸   NM_031052
- Peptide Label: precursor
- UniProtKB: Q01992 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008769001   ⟸   XM_008770779
- Peptide Label: isoform X2
- UniProtKB: Q01992 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018845   ⟸   ENSRNOT00000018845
Ensembl Acc Id: ENSRNOP00000073167   ⟸   ENSRNOT00000085785
RefSeq Acc Id: XP_038949613   ⟸   XM_039093685
- Peptide Label: isoform X1
- UniProtKB: Q01992 (UniProtKB/Swiss-Prot),   A0A0G2K4T8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130763   ⟸   XM_063274693
- Peptide Label: isoform X3
Protein Domains
Peptidase M3A/M3B catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q01992-F1-model_v2 AlphaFold Q01992 1-710 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699737
Promoter ID:EPDNEW_R10261
Type:initiation region
Name:Mipep_1
Description:mitochondrial intermediate peptidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01541,084,197 - 41,084,257EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621680 AgrOrtholog
BioCyc Gene G2FUF-13517 BioCyc
Ensembl Genes ENSRNOG00000013876 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018845.5 UniProtKB/TrEMBL
  ENSRNOT00000085785.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1370.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.1370.40 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro M3A_MIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurolysin/TOP_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M3A_M3B UniProtKB/Swiss-Prot
  Pept_M3A_M3B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M3A_M3B UniProtKB/TrEMBL
NCBI Gene 81684 ENTREZGENE
PANTHER MITOCHONDRIAL INTERMEDIATE PEPTIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11804 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_M3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mipep PhenoGen
PROSITE ZINC_PROTEASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013876 RatGTEx
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K4T8 ENTREZGENE, UniProtKB/TrEMBL
  A6K6A6_RAT UniProtKB/TrEMBL
  A6K6A7_RAT UniProtKB/TrEMBL
  F1LPX0_RAT UniProtKB/TrEMBL
  MIPEP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Mipep  mitochondrial intermediate peptidase      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Mipep  mitochondrial intermediate peptidase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a HEXXH motif, typical of zinc metallopeptidases 728913
gene_protein 710 amino acids 728913