Mipep (mitochondrial intermediate peptidase) - Rat Genome Database

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Gene: Mipep (mitochondrial intermediate peptidase) Rattus norvegicus
Analyze
Symbol: Mipep
Name: mitochondrial intermediate peptidase
RGD ID: 621680
Description: Enables endopeptidase activity. Predicted to be involved in peptide metabolic process and protein processing involved in protein targeting to mitochondrion. Located in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 31. Orthologous to human MIPEP (mitochondrial intermediate peptidase); PARTICIPATES IN presequence pathway of mitochondrial protein import; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MIP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81539,102,301 - 39,227,915 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1539,102,115 - 39,227,914 (+)EnsemblGRCr8
mRatBN7.21534,926,198 - 35,051,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,926,207 - 35,051,727 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1536,787,866 - 36,893,767 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,938,483 - 38,044,388 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01536,387,341 - 36,492,974 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01541,084,180 - 41,192,621 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1541,084,206 - 41,190,005 (+)Ensemblrn6Rnor6.0
Rnor_5.01544,896,328 - 45,002,041 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41539,871,329 - 39,990,743 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1534,627,565 - 34,731,545 (+)NCBICelera
RGSC_v3.11539,887,028 - 40,006,443 (+)NCBI
Cytogenetic Map15p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
Brodifacoum  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
finasteride  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
glafenine  (EXP)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
methapyrilene  (EXP,ISO)
methidathion  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
nitrofen  (EXP)
nobiletin  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phytoestrogen  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
Tanshinone I  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrial matrix  (IDA,IEA)
mitochondrion  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue. Isaya G, etal., Proc Natl Acad Sci U S A 1992 Sep 1;89(17):8317-21.
3. Rat liver mitochondrial intermediate peptidase (MIP): purification and initial characterization. Kalousek F, etal., EMBO J. 1992 Aug;11(8):2803-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Processing of mitochondrial presequences. Mossmann D, etal., Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):1098-106. doi: 10.1016/j.bbagrm.2011.11.007. Epub 2011 Dec 7.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:14651853   PMID:18614015  


Genomics

Comparative Map Data
Mipep
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81539,102,301 - 39,227,915 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1539,102,115 - 39,227,914 (+)EnsemblGRCr8
mRatBN7.21534,926,198 - 35,051,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,926,207 - 35,051,727 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1536,787,866 - 36,893,767 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,938,483 - 38,044,388 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01536,387,341 - 36,492,974 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01541,084,180 - 41,192,621 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1541,084,206 - 41,190,005 (+)Ensemblrn6Rnor6.0
Rnor_5.01544,896,328 - 45,002,041 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41539,871,329 - 39,990,743 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1534,627,565 - 34,731,545 (+)NCBICelera
RGSC_v3.11539,887,028 - 40,006,443 (+)NCBI
Cytogenetic Map15p12NCBI
MIPEP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381323,730,189 - 23,889,400 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1323,730,176 - 23,889,448 (-)Ensemblhg38GRCh38
GRCh371324,304,328 - 24,463,539 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361323,202,328 - 23,361,559 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341323,202,328 - 23,361,533NCBI
Celera135,366,999 - 5,526,241 (-)NCBICelera
Cytogenetic Map13q12.12NCBI
HuRef135,115,419 - 5,274,678 (-)NCBIHuRef
CHM1_11324,272,481 - 24,431,743 (-)NCBICHM1_1
T2T-CHM13v2.01322,936,639 - 23,095,878 (-)NCBIT2T-CHM13v2.0
Mipep
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391461,022,011 - 61,142,930 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1461,022,022 - 61,142,927 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381460,784,562 - 60,905,481 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1460,784,573 - 60,905,478 (+)Ensemblmm10GRCm38
MGSCv371461,403,403 - 61,522,450 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361459,738,692 - 59,859,588 (+)NCBIMGSCv36mm8
Celera1458,563,091 - 58,670,430 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1431.95NCBI
Mipep
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554974,062,677 - 4,196,889 (-)Ensembl
ChiLan1.0NW_0049554974,065,090 - 4,196,999 (-)NCBIChiLan1.0ChiLan1.0
MIPEP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21423,344,721 - 23,512,342 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11314,451,978 - 14,624,321 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0135,040,237 - 5,207,674 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11323,334,266 - 23,500,582 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1323,334,267 - 23,500,582 (-)EnsemblpanPan2panpan1.1
MIPEP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12514,755,474 - 14,930,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2514,753,596 - 14,930,369 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2514,833,115 - 15,007,225 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02514,886,171 - 15,060,823 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2514,886,180 - 15,062,683 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12514,767,513 - 14,942,058 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02514,770,383 - 14,944,826 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02514,818,700 - 14,993,399 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mipep
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945116,980,530 - 117,124,623 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366881,592,821 - 1,737,282 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366881,592,810 - 1,736,896 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIPEP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl112,670,000 - 2,790,727 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1112,675,604 - 2,790,760 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2112,039,126 - 2,144,089 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIPEP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.133,578,057 - 3,726,783 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl33,578,193 - 3,726,746 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605740,804,644 - 41,015,711 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mipep
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477613,880,417 - 14,037,610 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477613,877,579 - 14,034,875 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mipep
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11263,544,212 - 63,647,748 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mipep
508 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:52
Interacting mature miRNAs:54
Transcripts:ENSRNOT00000018845
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat

Markers in Region
D15Rat86  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,924,510 - 34,924,750 (+)MAPPERmRatBN7.2
Rnor_6.01541,082,490 - 41,082,727NCBIRnor6.0
Rnor_5.01544,894,605 - 44,894,842UniSTSRnor5.0
RGSC_v3.41539,869,606 - 39,869,843UniSTSRGSC3.4
RGSC_v3.41539,869,605 - 39,869,843RGDRGSC3.4
Celera1534,625,858 - 34,626,095UniSTS
RGSC_v3.11539,885,276 - 39,885,610RGD
SHRSP x BN Map1527.8098UniSTS
SHRSP x BN Map1527.8098RGD
Cytogenetic Map15p12UniSTS
BE117302  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,999,339 - 34,999,499 (+)MAPPERmRatBN7.2
Rnor_6.01541,157,052 - 41,157,211NCBIRnor6.0
Rnor_5.01544,969,174 - 44,969,333UniSTSRnor5.0
RGSC_v3.41539,956,612 - 39,956,771UniSTSRGSC3.4
Celera1534,698,673 - 34,698,832UniSTS
RH 3.4 Map15229.5UniSTS
Cytogenetic Map15p12UniSTS
AU048566  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21535,003,975 - 35,004,185 (+)MAPPERmRatBN7.2
Rnor_6.01541,161,688 - 41,161,897NCBIRnor6.0
Rnor_5.01544,973,810 - 44,974,019UniSTSRnor5.0
RGSC_v3.41539,961,248 - 39,961,457UniSTSRGSC3.4
Celera1534,703,309 - 34,703,518UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR459947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM061883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM065705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM100741 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM117087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FN806671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB965597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HD023007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M96633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018845   ⟹   ENSRNOP00000018845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1539,102,320 - 39,208,347 (+)Ensembl
mRatBN7.2 Ensembl1534,926,223 - 35,032,245 (+)Ensembl
Rnor_6.0 Ensembl1541,084,213 - 41,189,894 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085785   ⟹   ENSRNOP00000073167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1539,102,320 - 39,227,914 (+)Ensembl
mRatBN7.2 Ensembl1534,926,207 - 35,051,727 (+)Ensembl
Rnor_6.0 Ensembl1541,084,206 - 41,190,005 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146427   ⟹   ENSRNOP00000098835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1539,102,329 - 39,211,042 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000162084   ⟹   ENSRNOP00000110169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1539,102,115 - 39,211,042 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000163454   ⟹   ENSRNOP00000104331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1539,102,317 - 39,211,042 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000164189   ⟹   ENSRNOP00000103623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1539,102,314 - 39,211,042 (+)Ensembl
RefSeq Acc Id: NM_031052   ⟹   NP_112314
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,327 - 39,208,348 (+)NCBI
mRatBN7.21534,926,220 - 35,032,246 (+)NCBI
Rnor_6.01541,084,197 - 41,189,926 (+)NCBI
Rnor_5.01544,896,328 - 45,002,041 (+)NCBI
RGSC_v3.41539,871,329 - 39,990,743 (+)RGD
Celera1534,627,565 - 34,731,545 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770779   ⟹   XP_008769001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,301 - 39,208,348 (+)NCBI
mRatBN7.21534,926,198 - 35,034,941 (+)NCBI
Rnor_6.01541,084,180 - 41,192,621 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039093685   ⟹   XP_038949613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,301 - 39,227,915 (+)NCBI
mRatBN7.21534,926,198 - 35,051,722 (+)NCBI
RefSeq Acc Id: XM_063274693   ⟹   XP_063130763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81539,102,301 - 39,143,871 (+)NCBI
RefSeq Acc Id: NP_112314   ⟸   NM_031052
- Peptide Label: precursor
- UniProtKB: Q01992 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008769001   ⟸   XM_008770779
- Peptide Label: isoform X2
- UniProtKB: Q01992 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018845   ⟸   ENSRNOT00000018845
Ensembl Acc Id: ENSRNOP00000073167   ⟸   ENSRNOT00000085785
RefSeq Acc Id: XP_038949613   ⟸   XM_039093685
- Peptide Label: isoform X1
- UniProtKB: Q01992 (UniProtKB/Swiss-Prot),   A0A0G2K4T8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130763   ⟸   XM_063274693
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000103623   ⟸   ENSRNOT00000164189
Ensembl Acc Id: ENSRNOP00000098835   ⟸   ENSRNOT00000146427
Ensembl Acc Id: ENSRNOP00000110169   ⟸   ENSRNOT00000162084
Ensembl Acc Id: ENSRNOP00000104331   ⟸   ENSRNOT00000163454
Protein Domains
Peptidase M3A/M3B catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q01992-F1-model_v2 AlphaFold Q01992 1-710 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699737
Promoter ID:EPDNEW_R10261
Type:initiation region
Name:Mipep_1
Description:mitochondrial intermediate peptidase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01541,084,197 - 41,084,257EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621680 AgrOrtholog
BioCyc Gene G2FUF-13517 BioCyc
Ensembl Genes ENSRNOG00000013876 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000085785 ENTREZGENE
  ENSRNOT00000162084 ENTREZGENE
  ENSRNOT00000163454 ENTREZGENE
Gene3D-CATH 1.10.1370.10 UniProtKB/Swiss-Prot
  3.40.390.10 UniProtKB/Swiss-Prot
InterPro M3A_MIP UniProtKB/Swiss-Prot
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot
  Neurolysin/TOP_dom2 UniProtKB/Swiss-Prot
  Pept_M3A_M3B UniProtKB/Swiss-Prot
  Pept_M3A_M3B UniProtKB/Swiss-Prot
NCBI Gene 81684 ENTREZGENE
PANTHER MITOCHONDRIAL INTERMEDIATE PEPTIDASE UniProtKB/Swiss-Prot
  PTHR11804 UniProtKB/Swiss-Prot
Pfam Peptidase_M3 UniProtKB/Swiss-Prot
PhenoGen Mipep PhenoGen
PROSITE ZINC_PROTEASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013876 RatGTEx
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot
UniProt A0A0G2K4T8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LCD1_RAT UniProtKB/TrEMBL
  A0ABK0LI23_RAT UniProtKB/TrEMBL
  A0ABK0LJA8_RAT UniProtKB/TrEMBL
  A0ABK0LY70_RAT UniProtKB/TrEMBL
  A6K6A6_RAT UniProtKB/TrEMBL
  A6K6A7_RAT UniProtKB/TrEMBL
  F1LPX0_RAT UniProtKB/TrEMBL
  MIPEP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Mipep  mitochondrial intermediate peptidase      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Mipep  mitochondrial intermediate peptidase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a HEXXH motif, typical of zinc metallopeptidases 728913
gene_protein 710 amino acids 728913