Tpt1 (tumor protein, translationally-controlled 1) - Rat Genome Database

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Gene: Tpt1 (tumor protein, translationally-controlled 1) Rattus norvegicus
Analyze
Symbol: Tpt1 (Ensembl: Tpt1l2)
Name: tumor protein, translationally-controlled 1 (Ensembl:tumor protein, translationally-controlled 1 like 2)
RGD ID: 621623
Description: Predicted to enable DNA-binding transcription factor binding activity and calcium ion binding activity. Involved in spermatogenesis. Predicted to be located in several cellular components, including microtubule cytoskeleton; multivesicular body; and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to several human genes including TPT1 (tumor protein, translationally-controlled 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,4,5,3',4',5'-Hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: lens epithelial protein; MGC105360; TCTP; translationally-controlled tumor protein
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Tpt1-ps1   Tpt1-ps2  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81557,562,217 - 57,568,968 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1557,566,067 - 57,569,554 (+)EnsemblGRCr8
mRatBN7.21551,156,728 - 51,159,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1551,146,154 - 51,159,625 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1555,314,971 - 55,317,799 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01556,433,295 - 56,436,123 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02143,694,853 - 143,695,646 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,891,680 - 57,894,504 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,891,680 - 57,894,504 (+)Ensemblrn6Rnor6.0
Rnor_5.01561,598,787 - 61,601,611 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41556,752,464 - 56,755,288 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1550,783,471 - 50,786,295 (+)NCBICelera
RGSC_v3.11556,768,246 - 56,771,068 (+)NCBI
Cytogenetic Map15q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(Z)-3-butylidenephthalide  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4,5,3',4',5'-Hexachlorobiphenyl  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aminoglutethimide  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
bufalin  (ISO)
cadmium dichloride  (ISO)
chlorogenic acid  (ISO)
chlorophyllin  (ISO)
chloropicrin  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
corn oil  (EXP)
Cuprizon  (EXP)
deoxynivalenol  (ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicyclanil  (ISO)
diuron  (EXP,ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
etoposide  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
methidathion  (ISO)
methomyl  (EXP)
miconazole  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
Osajin  (ISO)
ouabain  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorodecanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenanthrene  (ISO)
Pomiferin  (ISO)
potassium dichromate  (ISO)
pterostilbene  (ISO)
puerarin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
Rosavin  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
thapsigargin  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
zearalenone  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cellular distribution of translationally controlled tumor protein in rat and human testes. Guillaume E, etal., Proteomics 2001 Jul;1(7):880-9.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11156187   PMID:11368327   PMID:11598139   PMID:12477932   PMID:15162379   PMID:15319436   PMID:15489334   PMID:15958728   PMID:16548883   PMID:21076177   PMID:22658674   PMID:23533145  
PMID:24006456   PMID:26266488   PMID:27783042   PMID:29676587   PMID:31320615   PMID:32174219  


Genomics

Comparative Map Data
Tpt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81557,562,217 - 57,568,968 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1557,566,067 - 57,569,554 (+)EnsemblGRCr8
mRatBN7.21551,156,728 - 51,159,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1551,146,154 - 51,159,625 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1555,314,971 - 55,317,799 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01556,433,295 - 56,436,123 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02143,694,853 - 143,695,646 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,891,680 - 57,894,504 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,891,680 - 57,894,504 (+)Ensemblrn6Rnor6.0
Rnor_5.01561,598,787 - 61,601,611 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41556,752,464 - 56,755,288 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1550,783,471 - 50,786,295 (+)NCBICelera
RGSC_v3.11556,768,246 - 56,771,068 (+)NCBI
Cytogenetic Map15q11NCBI
TPT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381345,333,471 - 45,341,183 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1345,333,471 - 45,341,284 (-)Ensemblhg38GRCh38
GRCh371345,907,606 - 45,915,318 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361344,809,304 - 44,813,297 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341344,809,303 - 44,813,297NCBI
Celera1326,967,432 - 26,971,425 (-)NCBICelera
Cytogenetic Map13q14.13NCBI
HuRef1326,712,445 - 26,716,438 (-)NCBIHuRef
CHM1_11345,878,878 - 45,882,871 (-)NCBICHM1_1
T2T-CHM13v2.01344,553,718 - 44,561,430 (-)NCBIT2T-CHM13v2.0
Tpt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391476,082,771 - 76,085,743 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1476,082,533 - 76,085,965 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381475,845,256 - 75,848,303 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,845,093 - 75,848,525 (+)Ensemblmm10GRCm38
MGSCv371476,245,063 - 76,248,110 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361474,579,486 - 74,582,453 (+)NCBIMGSCv36mm8
Celera1473,346,596 - 73,349,642 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1440.29NCBI
TPT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21444,856,762 - 44,860,771 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11335,918,723 - 35,922,983 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01326,504,747 - 26,509,160 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13197,562,788 - 197,567,290 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3197,562,788 - 197,567,290 (+)EnsemblpanPan2panpan1.1
TPT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1225,711,076 - 5,715,254 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl225,711,071 - 5,715,069 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha225,700,382 - 5,704,539 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0225,829,066 - 5,833,209 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl225,829,061 - 5,923,975 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1225,611,060 - 5,615,216 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0225,674,049 - 5,678,187 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0225,679,693 - 5,683,850 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tpt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945155,519,429 - 155,523,389 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367911,440,004 - 1,443,959 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367911,439,997 - 1,443,959 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,929,221 - 21,932,691 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11121,929,294 - 21,932,905 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TPT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1323,428,523 - 23,432,846 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl323,429,044 - 23,433,108 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605720,628,861 - 20,633,369 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247489,657,037 - 9,660,923 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247489,657,041 - 9,660,924 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tpt1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11248,567,468 - 48,570,436 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tpt1
43 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:163
Count of miRNA genes:130
Interacting mature miRNAs:145
Transcripts:ENSRNOT00000001383
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1544806773104695021Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155720389580107161Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)154367724488677244Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)154046315285463152Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)154367724488677244Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)154367724488677244Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)154367724488677244Rat

Markers in Region
RH141654  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21551,159,762 - 51,159,965 (+)MAPPERmRatBN7.2
Rnor_6.01557,894,643 - 57,894,845NCBIRnor6.0
Rnor_5.01561,601,750 - 61,601,952UniSTSRnor5.0
RGSC_v3.41556,755,427 - 56,755,629UniSTSRGSC3.4
Celera1550,786,434 - 50,786,636UniSTS
Cytogenetic Map15q11UniSTS
MARC_2026-2027:991932441:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2119,107,509 - 19,107,862 (+)MAPPERmRatBN7.2
Rnor_6.0120,116,022 - 20,116,374NCBIRnor6.0
Rnor_5.0121,603,371 - 21,603,723UniSTSRnor5.0
RGSC_v3.4119,563,457 - 19,563,809UniSTSRGSC3.4
Celera117,499,214 - 17,499,566UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map15q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 13 84 217 91 90 59 152 59 6 485 279 22 195 116 124 31 34 34

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC086358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000001383   ⟹   ENSRNOP00000001383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1557,566,067 - 57,569,554 (+)Ensembl
mRatBN7.2 Ensembl1551,156,708 - 51,159,625 (+)Ensembl
Rnor_6.0 Ensembl1557,891,680 - 57,894,504 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106386   ⟹   ENSRNOP00000082883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1551,146,154 - 51,159,625 (+)Ensembl
RefSeq Acc Id: NM_053867   ⟹   NP_446319
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81557,566,144 - 57,568,968 (+)NCBI
mRatBN7.21551,156,800 - 51,159,624 (+)NCBI
Rnor_6.01557,891,680 - 57,894,504 (+)NCBI
Rnor_5.01561,598,787 - 61,601,611 (+)NCBI
RGSC_v3.41556,752,464 - 56,755,288 (+)RGD
Celera1550,783,471 - 50,786,295 (+)RGD
Sequence:
RefSeq Acc Id: XM_063273908   ⟹   XP_063129978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81557,566,045 - 57,568,968 (+)NCBI
RefSeq Acc Id: XM_063273909   ⟹   XP_063129979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81557,562,222 - 57,568,968 (+)NCBI
RefSeq Acc Id: XM_063273910   ⟹   XP_063129980
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81557,562,217 - 57,568,968 (+)NCBI
RefSeq Acc Id: XM_063273911   ⟹   XP_063129981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81557,566,045 - 57,568,057 (+)NCBI
RefSeq Acc Id: NP_446319   ⟸   NM_053867
- UniProtKB: P14701 (UniProtKB/Swiss-Prot),   P63029 (UniProtKB/Swiss-Prot),   A6HTT6 (UniProtKB/TrEMBL),   A0A8I5ZVT0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001383   ⟸   ENSRNOT00000001383
Ensembl Acc Id: ENSRNOP00000082883   ⟸   ENSRNOT00000106386
RefSeq Acc Id: XP_063129980   ⟸   XM_063273910
- Peptide Label: isoform X2
- UniProtKB: P14701 (UniProtKB/Swiss-Prot),   P63029 (UniProtKB/Swiss-Prot),   A6HTT6 (UniProtKB/TrEMBL),   A0A8I5ZVT0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129979   ⟸   XM_063273909
- Peptide Label: isoform X2
- UniProtKB: P14701 (UniProtKB/Swiss-Prot),   P63029 (UniProtKB/Swiss-Prot),   A6HTT6 (UniProtKB/TrEMBL),   A0A8I5ZVT0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063129978   ⟸   XM_063273908
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063129981   ⟸   XM_063273911
- Peptide Label: isoform X3
- UniProtKB: A6HTT8 (UniProtKB/TrEMBL)
Protein Domains
TCTP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63029-F1-model_v2 AlphaFold P63029 1-172 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699835
Promoter ID:EPDNEW_R10358
Type:multiple initiation site
Name:Tpt1_1
Description:tumor protein, translationally-controlled 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01557,891,651 - 57,891,711EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621623 AgrOrtholog
BioCyc Gene G2FUF-13106 BioCyc
Ensembl Genes ENSRNOG00000001049 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001383 ENTREZGENE
  ENSRNOT00000001383.8 UniProtKB/Swiss-Prot
Gene3D-CATH Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7303675 IMAGE-MGC_LOAD
InterPro Mss4-like_sf UniProtKB/Swiss-Prot
  Mss4/transl-control_tumour UniProtKB/Swiss-Prot
  TCTP UniProtKB/Swiss-Prot
  Translation_control_tumour_CS UniProtKB/Swiss-Prot
  Translational_control_tumour_p UniProtKB/Swiss-Prot
KEGG Report rno:116646 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105360 IMAGE-MGC_LOAD
NCBI Gene 116646 ENTREZGENE
PANTHER PTHR11991 UniProtKB/Swiss-Prot
  TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN UniProtKB/Swiss-Prot
Pfam TCTP UniProtKB/Swiss-Prot
PhenoGen Tpt1 PhenoGen
PRINTS TCTPROTEIN UniProtKB/Swiss-Prot
PROSITE TCTP_1 UniProtKB/Swiss-Prot
  TCTP_2 UniProtKB/Swiss-Prot
  TCTP_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001049 RatGTEx
Superfamily-SCOP SSF51316 UniProtKB/Swiss-Prot
UniProt A0A8I5ZVT0 ENTREZGENE
  A6HTT6 ENTREZGENE, UniProtKB/TrEMBL
  A6HTT8 ENTREZGENE, UniProtKB/TrEMBL
  P14701 ENTREZGENE
  P63029 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P14701 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Tpt1  tumor protein, translationally-controlled 1      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Tpt1  tumor protein, translationally-controlled 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression enriched in spermatogonia; present in Leydig, resident macrophage, peritubular and Sertoli cells 724749