Trim23 (tripartite motif-containing 23)

Gene: Trim23 (tripartite motif-containing 23) Rattus norvegicus

Analyze

Symbol:

Trim23

Name:

tripartite motif-containing 23

RGD ID:

621587

Description:

Enables GTP binding activity. Involved in positive regulation of protein modification process. Predicted to be located in Golgi membrane and nucleus. Predicted to be active in lysosomal membrane and plasma membrane. Orthologous to human TRIM23 (tripartite motif containing 23); INTERACTS WITH aflatoxin B1; ammonium chloride; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ADP-ribosylation factor domain protein 1 64kD; ADP-ribosylation factor domain protein 1, 64kD; ADP-ribosylation factor domain-containing protein 1; Ard1; Arfd1; E3 ubiquitin-protein ligase TRIM23; GTP-binding protein ARD-1; nucleotide binding protein; RING-type E3 ubiquitin transferase TRIM23; tripartite motif protein 23; tripartite motif-containing protein 23

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRIM23 (tripartite motif containing 23)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Trim23 (tripartite motif-containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Trim23 (tripartite motif containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRIM23 (tripartite motif containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRIM23 (tripartite motif containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Trim23 (tripartite motif containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRIM23 (tripartite motif containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRIM23 (tripartite motif containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Trim23 (tripartite motif containing 23)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ZNF503 (zinc finger protein 503)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Trim23 (tripartite motif-containing 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TRIM23 (tripartite motif containing 23)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	trim23 (tripartite motif containing 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	arc-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	trim23	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	37,036,193 - 37,069,024 (+)	NCBI		GRCr8
mRatBN7.2	2	35,302,405 - 35,335,746 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	35,302,409 - 35,335,743 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	42,415,324 - 42,448,196 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	40,474,019 - 40,506,883 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	35,330,679 - 35,363,505 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	34,255,300 - 34,288,140 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	34,255,305 - 34,288,139 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	53,383,587 - 53,416,926 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	35,101,019 - 35,135,028 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	35,021,536 - 35,053,519 (+)	NCBI
Celera	2	31,278,878 - 31,311,698 (+)	NCBI		Celera
Cytogenetic Map	2	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-nitropyrene (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

5-aza-2'-deoxycytidine (ISO)

aflatoxin B1 (EXP)

ammonium chloride (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

C60 fullerene (EXP)

cadmium dichloride (EXP)

chlorpyrifos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dicrotophos (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

gefitinib (ISO)

genistein (ISO)

gentamycin (EXP)

gold atom (ISO)

gold(0) (ISO)

haloperidol (EXP)

ketoconazole (ISO)

lead(0) (ISO)

leflunomide (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

naphthalene (ISO)

nickel atom (ISO)

paracetamol (EXP,ISO)

phenobarbital (ISO)

pirinixic acid (EXP)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

Soman (EXP)

thimerosal (ISO)

torcetrapib (ISO)

trichostatin A (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular protein transport (IBA)

positive regulation of autophagy (IEA,ISO)

positive regulation of protein modification process (IDA)

protein ubiquitination (IEA,ISO,ISS)

vesicle-mediated transport (IBA)

Cellular Component

cytoplasm (ISO)

Golgi membrane (IEA,ISO,ISS)

lysosomal membrane (IBA,IEA,ISO,ISS)

nucleus (IEA,ISO)

plasma membrane (IBA)

Molecular Function

GDP binding (IEA,ISO,ISS)

GTP binding (IDA,IEA,ISO,ISS)

GTPase activity (IEA,ISO,ISS)

identical protein binding (IEA,ISO)

protein binding (ISO)

transferase activity (IEA)

ubiquitin protein ligase activity (IEA,ISO)

ubiquitin-protein transferase activity (ISO,ISS)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ARD 1, a 64-kDa guanine nucleotide-binding protein with a carboxyl-terminal ADP-ribosylation factor domain.	Mishima K, etal., J Biol Chem 1993 Apr 25;268(12):8801-7.
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8700863	PMID:8889548	PMID:9671726	PMID:11331580	PMID:15684077	PMID:16189514	PMID:22493164	PMID:22871113	PMID:23376485	PMID:25416956	PMID:31621984	PMID:37495427

Genomics

Comparative Map Data

Trim23
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	37,036,193 - 37,069,024 (+)	NCBI		GRCr8
mRatBN7.2	2	35,302,405 - 35,335,746 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	35,302,409 - 35,335,743 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	42,415,324 - 42,448,196 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	40,474,019 - 40,506,883 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	35,330,679 - 35,363,505 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	34,255,300 - 34,288,140 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	34,255,305 - 34,288,139 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	53,383,587 - 53,416,926 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	35,101,019 - 35,135,028 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	35,021,536 - 35,053,519 (+)	NCBI
Celera	2	31,278,878 - 31,311,698 (+)	NCBI		Celera
Cytogenetic Map	2	q13	NCBI

TRIM23
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	65,589,690 - 65,624,333 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	65,589,690 - 65,625,975 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	64,885,517 - 64,920,160 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	64,921,263 - 64,955,943 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	61,883,967 - 61,918,646 (-)	NCBI		Celera
Cytogenetic Map	5	q12.3	NCBI
HuRef	5	61,841,543 - 61,876,240 (-)	NCBI		HuRef
CHM1_1	5	64,885,060 - 64,919,737 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	66,411,457 - 66,448,919 (-)	NCBI		T2T-CHM13v2.0

Trim23
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	104,315,187 - 104,339,983 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	104,315,305 - 104,339,880 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	104,178,839 - 104,203,475 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	104,178,797 - 104,203,372 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	104,969,178 - 104,992,128 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	105,299,480 - 105,322,430 (+)	NCBI		MGSCv36	mm8
Celera	13	108,571,875 - 108,594,822 (+)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI
cM Map	13	56.35	NCBI

Trim23
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	3,479,858 - 3,509,050 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955446	3,480,177 - 3,509,050 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRIM23
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	48,297,784 - 48,332,434 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	46,451,411 - 46,486,044 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	48,382,696 - 48,417,349 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	50,036,475 - 50,071,457 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	50,036,475 - 50,071,457 (+)	Ensembl	panpan1.1		panPan2

TRIM23
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	51,323,341 - 51,360,193 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	51,325,038 - 51,360,117 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	48,278,874 - 48,316,065 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	51,814,356 - 51,851,549 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	51,814,365 - 51,851,549 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	48,874,086 - 48,911,283 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	49,663,193 - 49,700,381 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	50,555,618 - 50,592,810 (-)	NCBI		UU_Cfam_GSD_1.0

Trim23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	194,621,173 - 194,657,440 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	3,556,592 - 3,592,984 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	3,557,699 - 3,593,514 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIM23
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	44,103,789 - 44,146,280 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	44,103,339 - 44,146,291 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	47,452,599 - 47,495,545 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM23
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	61,781,880 - 61,816,670 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	61,784,002 - 61,816,638 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	10,424,835 - 10,459,559 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trim23
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624815	4,246,884 - 4,287,316 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624815	4,246,939 - 4,289,262 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Trim23
84 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	477
Count of miRNA genes:	215
Interacting mature miRNAs:	252
Transcripts:	ENSRNOT00000016596, ENSRNOT00000016649
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631682	Bp115	Blood pressure QTL 115	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	1	37410502	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	41244106	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	7887772	42804738	Rat
738012	Anxrr3	Anxiety related response QTL 3	3.8		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	2	9023519	54023519	Rat
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	11591100	56591100	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	11852062	49003364	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	16491740	61491740	Rat
1357990	Ael1	Aortic elastin QTL 1	3.1	0.00091	aorta elastin amount (VT:0003905)	aortic elastin	2	19076825	64076825	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	20304672	65304672	Rat
2300168	Bmd47	Bone mineral density QTL 47	6.6	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	2	20662448	65662448	Rat
10402051	Gdil2	Gastrointestinal dilation QTL 2			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	24903853	74786777	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	81754745	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	127469484	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	26917817	136917119	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26999571	43154682	Rat
1643006	Pain1	Pain QTL 1	3.63	0.005	mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	2	26999571	48268661	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	27157160	72157160	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	29971593	51729300	Rat
10755434	Coatc7	Coat color QTL 7		0.04794	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	30648065	75648065	Rat
731179	Mamtr3	Mammary tumor resistance QTL 3		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	32373770	43665178	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	35023117	80023117	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	35134841	88029593	Rat

Markers in Region

RH129699

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	35,334,954 - 35,335,135 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	34,287,853 - 34,288,033	NCBI	Rnor6.0
Rnor_5.0	2	53,416,639 - 53,416,819	UniSTS	Rnor5.0
RGSC_v3.4	2	35,134,112 - 35,134,292	UniSTS	RGSC3.4
Celera	2	31,311,411 - 31,311,591	UniSTS
RH 3.4 Map	2	152.7	UniSTS
Cytogenetic Map	2	q13	UniSTS

RH144040

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	35,336,067 - 35,336,250 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	34,288,966 - 34,289,148	NCBI	Rnor6.0
Rnor_5.0	2	53,417,752 - 53,417,934	UniSTS	Rnor5.0
RGSC_v3.4	2	35,135,225 - 35,135,407	UniSTS	RGSC3.4
Celera	2	31,312,524 - 31,312,706	UniSTS
RH 3.4 Map	2	154.4	UniSTS
Cytogenetic Map	2	q13	UniSTS

MARC_15693-15694:1017691889:1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	35,330,423 - 35,331,042 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	34,283,322 - 34,283,940	NCBI	Rnor6.0
Rnor_5.0	2	53,412,054 - 53,412,672	UniSTS	Rnor5.0
RGSC_v3.4	2	35,129,582 - 35,130,200	UniSTS	RGSC3.4
Celera	2	31,306,890 - 31,307,508	UniSTS
Cytogenetic Map	2	q13	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		40	34	18	17	18	8	10	74	32	40	11	8
Low	3	3	23	23	2	23		1		3	1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA965268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC129167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB696360	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK470479	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DV726798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM052834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM085917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L04760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000016596 ⟹ ENSRNOP00000016597

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	35,302,451 - 35,335,231 (+)	Ensembl
Rnor_6.0 Ensembl	2	34,255,317 - 34,286,858 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000016649 ⟹ ENSRNOP00000016647

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	35,302,409 - 35,335,239 (+)	Ensembl
Rnor_6.0 Ensembl	2	34,255,305 - 34,288,139 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106700 ⟹ ENSRNOP00000088434

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	35,302,452 - 35,335,743 (+)	Ensembl

RefSeq Acc Id:

NM_001100637 ⟹ NP_001094107

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	37,036,193 - 37,069,024 (+)	NCBI
mRatBN7.2	2	35,302,405 - 35,335,242 (+)	NCBI
Rnor_6.0	2	34,255,305 - 34,288,140 (+)	NCBI
Rnor_5.0	2	53,383,587 - 53,416,926 (+)	NCBI
Celera	2	31,278,878 - 31,311,698 (+)	NCBI

Sequence:

show sequence

GCGGCACGCGCCGAGGCTTCTGGGTAGGTCGCTCAACCCCTCCTCTCAGTTAAAGGCTCTACTG
CAGCTGTGCCGCTGCTCCTTCCAGGATGGCTGCCCTCGCTGTAAACAAGCCCGGAGCAGGAGTA
GACAGTGGGCGGCAGGGCAGCCGGGGGACGGCTGTGGTGAAGGTTCTGGAGTGTGGTGTTTGTG
AAGATGTCTTCTCTCTGCAAGGAGATAAAGTTCCTCGCCTTCTCCTTTGTGGCCACACAGTCTG
TCATGACTGTCTCTCTCGCTTGCCTCTGCATGGAAGAGCAATACGTTGCCCATTTGATCGACAA
GTGACAGACCTAGGAGATTCAGGTGTCTGGGGTTTGAAAAAAAATTTTGCTTTACTGGAGCTTT
TAGAACGTTTGCAAAATGGACATATTGGTCAGTATGGAGCTGCAGAAGAAGCCCTTGGGATATC
TGGAGAGAGTATCATTCGCTGTGATGAAGATGAAGCTCACGTTGCATCTGTGTACTGCACTGTG
TGTGCGACTCACTTGTGCTCAGAGTGTTCTCAAGTCACTCATTCTACAAAGACTCTGGCCAAGC
ATAGGCGAGTGCCTCTAGCTGATAAACCTCATGAGAAGACCATGTGCTGTCAGCACCAGGTACA
TGCCATTGAGTTTGTTTGCTTGGAAGAAGCTTGTCAAACTAGTCCTCTCATGTGCTGTGTCTGC
AAAGAATATGGAAAACACCAGGGTCACAAGCACTCAGTACTGGAGCCAGAAGCTAACCAGATCC
GAGCGTCAATTTTAGACATGGCTCACTGCATACGAACCTTCACTGAGGAGATCTCAGATTATTC
CAGAAAATTAGTTGGGATTGTTCAGCACATTGAAGGAGGAGAACAAATAGTGGAAGATGGAATT
GGAATGGCTCACACGGAACACGTCCCAGGTACTGCAGAGAATGCACGATCATGTGTCAGAGCTT
ATTTTTCTGATTTGCATGAAACTCTTTGTCGTCAAGAAGAAATGGCTCTCAGTGTTGTTGATGC
CCATGTTCGAGAAAAACTGATTTGGCTTAGGCAGCAACAAGAGGATATGACTATTCTCTTGTCC
CAGGTTTCAACAGCCTGTCTCCATTGTGAAAAGACTTTGCAGCAGGATGATTGCAGAGTTGTCT
TGGCAAAACAAGAAATCACAAGATTATTAGAAACACTGCAGAAACAGCAGCAGCAGTTTACAGA
AGTTGCAGATCATATTCAGTTGGATGCCAGTATTCCAGTCACTTTTACAAAGGACAACAGAGTT
TATATTGGACCCAAAATGGAAATACGAGTAGTCACATTAGGATTAGATGGTGCTGGAAAAACTA
CTATTTTGTTCAAGTTAAAACAAGATGAATTTATGCAGCCTATTCCAACAATTGGTTTTAATGT
GGAAACTGTGGAATACAAAAATCTAAAATTCACCATTTGGGATGTGGGTGAAAAACACAAATTA
AGACCATTGTGGAAACATTATTACCTCAATACACAAGCTGTTGTATTTGTTGTTGACAGCAGTC
ACAGAGACAGAATTAGTGAAGCACACAGTGAACTTGCGAAGTTGTTAACAGAAAAAGAACTTCG
AGATGCCTTACTCTTGATTTTTGCTAACAAACAGGATGTCGCTGGGGCACTTTCGGTTGAAGAA
ATCACCGAACTTCTCAGTCTCCATAAATTATGCTGCGGAAGGAGCTGGTATATTCAGGGCTGTG
ATGCTCGAAGTGGTATGGGGCTCTACGAAGGGTTGGACTGGCTGTCCCGGCAACTTGTGGCTGC
CGGAGTGTTGGATGTTGCTTGATTCTATTGCAGCAGTTGTTTCGAGCTTATGGTTAAAAGTTAC
TTTGCATGTAATGCATTCTAAGAAATTCTACATCTCAAGTATGATAATTTAGTATGTGTACGTA
TGAATCCTGGACTGAGAAATGTACCATTGCTTTTAAAAATTATTCTGTGGCAAATTTAAGTGAT
CCTGTTACATTGGTTAAATAGTTTTGCTTTTGTTTTTTTTTGGATATAAACTTTTAAAAGGTAC
ATTAGGCATTGGAAACTTTGTACACTTTGTGTATGACCTGTACATTGGGAGAGAAGTGGCCACA
GAGAATGAGTAGAAGCTCCTTTATTTTATTGAAAAAATAGGCAGTGGAGTGCCTAACAGAACTT
ATGGAAACATGGCTTCTTTACCCCTCCTTTTTACTCATTGTTGGCAGTCGTGGACTAGAATTTA
AGCTGTACTGGGGTAACAGGATTACCTGACTTTCACATTCAGCATAACATCTATTAGTGCTGGG
GACCATCAAATACAGAAAATCAGGGTTTTTTTCCCCTACAGTTTTATTATAACGCTCTCCTAAA
GCATTCTGCATAACGCACAATGAGAATGAATGTTATCTAAGTGGACCTGAGCATTAGACCCGAA
CTAAATTACGAACAATAGAACTGTGAAAGTTGTTTGATCTTCACTCATAAAAACCATTTCTAGG
ACTGGGCCTAGGTTTATTTCCTAGGTCAAAGCCCTAAATTGGTCCTTTCGTTCACACTTACTTA
GGCTAAGTAATAGTGCATCCTCTGTTGGTAAAGTGCCACAAGTCACATGAAGAACCAGTCACCT
TTACATAAACACACAGAGACCTAAATAGAAAACGGCCTAGACCTTAGGAAAGGTTTTCACACAG
TGGGGAATGCTAATTTCTTTAACATGGTTCCCAAGTTAAGTGCATTTACTAGACTATAAAAAAG
ATCAAGGCTCTTTAGGACAAGGTCTCAGTTAAAAGGAAGAACACATCTAAAGTAAAAGAAACTT
AAAAAGTTTACATTTATTACGGGAGTGTTATGAATAAAAGTTAAATTTTGTGTTCTCTATAGTT
TCTTATTTGTAAGATACTCTTATTATGGAAGCATGATTTCTTATATTTAAATAGGTAGATTTCT
TGTTATTAATGCTTTCACTTTAGGATGAAGTTGAGAGCTAAATCTTAGTGCAATTGTTAAAAGG
ACAGTGATGTCTGACAATAGGATGTGATTTTTAGGTGGCAATGTTCTGGTTCAGTTTTTCTCAA
ATAACCCTTTTTTTTAACTTAGAAAACAGCACTACAAAAAGTCCATCGAACATTATGGGCAACA
TGTAAATAAAAATATAATAATTTTCCCTTTTTCAAGAGTGTAACAACACGCTGTTACACATAGC
TTGTGTGCATATGTAATACACTGTAATTAAATTATTTAATTTTGACTGATTTTAGTAACTGTGA
AAAATAAAGACGTTGCGTTTATTTGTGAGAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008760683 ⟹ XP_008758905

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	37,036,205 - 37,069,022 (+)	NCBI
mRatBN7.2	2	35,302,417 - 35,335,746 (+)	NCBI
Rnor_6.0	2	34,255,301 - 34,288,138 (+)	NCBI

Sequence:

show sequence

GAGGGCGGCACGCGCCGAGGCTTCTGGGTAGGTCGCTCAACCCCTCCTCTCAGTTAAAGGCTCT
ACTGCAGCTGTGCCGCTGCTCCTTCCAGGATGGCTGCCCTCGCTGTAAACAAGCCCGGAGCAGG
AGTAGACAGTGGGCGGCAGGGCAGCCGGGGGACGGCTGTGGTGAAGACTATACATGAAATATTA
GCCCATGGACCTGAGTGTCAGAGTGAGCCAGTTCTCGCAGCTTTTCTTCCTCACTATCTTTCAG
TTCTGGAGTGTGGTGTTTGTGAAGATGTCTTCTCTCTGCAAGGAGATAAAGTTCCTCGCCTTCT
CCTTTGTGGCCACACAGTCTGTCATGACTGTCTCACACGCTTGCCTCTGCATGGAAGAGCAATA
CGTTGCCCATTTGATCGACAAGTGACAGACCTAGGAGATTCAGGTGTCTGGGGTTTGAAAAAAA
ATTTTGCTTTACTGGAGCTTTTAGAACGTTTGCAAAATGGACATATTGGTCAGTATGGAGCTGC
AGAAGAAGCCCTTGGGATATCTGGAGAGAGTATCATTCGCTGTGATGAAGATGAAGCTCACGTT
GCATCTGTGTACTGCACTGTGTGTGCGACTCACTTGTGCTCAGAGTGTTCTCAAGTCACACATT
CTACAAAGACACTGGCCAAGCATAGGCGAGTGCCTCTAGCTGATAAACCTCATGAGAAGACCAT
GTGCTGTCAGCACCAGGTACATGCCATTGAGTTTGTTTGCTTGGAAGAAGCTTGTCAAACTAGT
CCTCTCATGTGCTGTGTCTGCAAAGAATATGGAAAACACCAGGGTCACAAGCACTCAGTACTGG
AGCCAGAAGCTAACCAGATCCGAGCGTCAATTTTAGACATGGCTCACTGCATACGAACCTTCAC
TGAGGAGATCTCAGATTATTCCAGAAAATTAGTTGGGATTGTTCAGCACATTGAAGGAGGAGAA
CAAATAGTGGAAGATGGAATTGGAATGGCTCACACGGAACACGTCCCAGGTACTGCAGAGAATG
CACGATCATGTGTCAGAGCTTATTTTTCTGATTTGCATGAAACTCTTTGTCGTCAAGAAGAAAT
GGCTCTCAGTGTTGTTGATGCCCATGTTCGAGAAAAACTGATTTGGCTTAGGCAGCAACAAGAG
GATATGACTATTCTCTTGTCCCAGGTTTCAACAGCCTGTCTCCATTGTGAAAAGACTTTGCAGC
AGGATGATTGCAGAGTTGTCTTGGCAAAACAAGAAATCACAAGATTATTAGAAACACTGCAGAA
ACAGCAGCAGCAGTTTACAGAAGTTGCAGATCATATTCAGTTGGATGCCAGTATTCCAGTCACT
TTTACAAAGGACAACAGAGTTCATATTGGACCCAAAATGGAAATCCGAGTAGTCACATTAGGAT
TAGATGGTGCTGGAAAAACTACTATTTTGTTCAAGTTAAAACAAGATGAATTTATGCAGCCTAT
TCCAACAATTGGTTTTAATGTGGAAACTGTGGAATACAAAAATCTAAAATTCACCATTTGGGAT
GTGGGTGGAAAACACAAATTAAGACCATTGTGGAAACATTATTACCTCAATACACAAGCTGTTG
TATTTGTTGTTGACAGCAGTCACAGAGACAGAATTAGTGAAGCACACAGTGAACTTGCGAAGTT
GTTAACAGAAAAAGAACTTCGAGATGCCTTACTCTTGATTTTTGCTAACAAACAGGATGTCGCT
GGGGCACTTTCGGTTGAAGAAATCACCGAACTTCTCAGTCTCCATAAATTATGCTGCGGAAGGA
GCTGGTATATTCAGGGCTGTGATGCTCGAAGTGGTATGGGGCTCTACGAAGGGTTGGACTGGCT
GTCCCGGCAACTTGTGGCTGCCGGAGTGTTGGATGTTGCTTGATTCTATTGCAGCAGTTGTTTC
GAGCTTATGGTTAAAAGTTACTTTGCATGTAATGCATTCTAAGAAATTCTACATCTCAAGTATG
ATAATTTAGTATGTGTACGTATGAATCCTGGACTGAGAAATGTACCATTGCTTTTAAAAATTAT
TCTGTGGCAAATTTAAGTGATCCTGTTACATTGGTTAAATAGTTTTGCTTTTGTTTTTTTTTGG
ATATAAACTTTTAAAAGGTACATTAGGCATTGGAAACTTTGTACACTTTGTGTATGACCTGTAC
ATTGGGAGAGAAGTGGCCACAGAGAATGAGTAGAAGCTCCTTTATTTTATTGAAAAAATAGGCA
GTGGAGTGCCTAACAGAACTTATGGAAACATGGCTTCTTTACCCCTCCTTTTTACTCATTGTTG
GCAGTCGTGGACTAGAATTTAAGCTGTACTGGGGTAACAGGATTACCTGACTTTCACATTCAGC
ATAACATCTATTAGTGCTGGGGACCATCAAATACAGAAAATCAGGGTTTTTTTCCCCTACAGTT
TTATTATAACGCTCTCCTAAAGCATTCTGCATAACGCACAATGAGAATGAATGTTATCTAAGTG
GACCTGAGCATTAGACCCGAACTAAATTACGAACAATAGAACTGTGAAAGTTGTTTGATCTTCA
CTCATAAAAACCATTTCTAGGACTGGGCCTAGGTTTATTTCCTAGGTCAAAGCCCTAAATTGGT
CCTTTCGTTCACACTTACTTAGGCTAAGTAATAGTGCATCCTCTGTTGGTAAAGTGCCACAAGT
CACATGAAGAACCAGTCACCTTTACATAAACACACAGAGACCTAAATAGAAAACGGCCTAGACC
TTAGGAAAGGTTTTCACACAGTGGGGAATGCTAATTTCTTTAACATGGTTCCCAAGTTAAGTGC
ATTTACTAGACTATAAAAAAGATCAAGGCTCTTTAGGACAAGGTCTCAGTTAAAAGGAAGAACA
CATCTAAAGTAAAAGAAACTTAAAAAGTTTACATTTATTACGGGAGTGTTATGAATAAAAGTTA
AATTTTGTGTTCTCTATAGTTTCTTATTTGTAAGATACTCTTATTATGGAAGCATGATTTCTTA
TATTTAAATAGGTAGATTTCTTGTTATTAATGCTTTCACTTTAGGATGAAGTTGAGAGCTAAAT
CTTAGTGCAATTGTTAAAAGGACAGTGATGTCTGACAATAGGATGTGATTTTTAGGTGGCAATG
TTCTGGTTCAGTTTTTCTCAAATAACCCTTTTTTTTAACTTAGAAAACAGCACTACAAAAAGTC
CATCGAACATTATGGGCAACATGTAAATAAAAATATAATAATTTTCCCTTTTTCAAGAGTGTAA
CAACACGCTGTTACACATAGCTTGTGTGCATATGTAATACACTGTAATTAAATTATTTAATTTT
GACTGATTTTAGTAACTGTGAAAAATAAAGACGTTGCGTTTATTTGTGA

hide sequence

RefSeq Acc Id:

XM_008760684 ⟹ XP_008758906

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	37,036,204 - 37,069,022 (+)	NCBI
mRatBN7.2	2	35,302,416 - 35,335,746 (+)	NCBI
Rnor_6.0	2	34,255,300 - 34,288,138 (+)	NCBI

Sequence:

show sequence

TGAGGGCGGCACGCGCCGAGGCTTCTGGGTAGGTCGCTCAACCCCTCCTCTCAGTTAAAGGCTC
TACTGCAGCTGTGCCGCTGCTCCTTCCAGGATGGCTGCCCTCGCTGTAAACAAGCCCGGAGCAG
GAGTAGACAGTGGGCGGCAGGGCAGCCGGGGGACGGCTGTGGTGAAGACTATACATGAAATATT
AGCCCATGGACCTGAGTGTCAGAGTGAGCCAGTTCTCGCAGCTTTTCTTCCTCACTATCTTTCA
GTTCTGGAGTGTGGTGTTTGTGAAGATGTCTTCTCTCTGCAAGGAGATAAAGTTCCTCGCCTTC
TCCTTTGTGGCCACACAGTCTGTCATGACTGTCTCACACGCTTGCCTCTGCATGGAAGAGCAAT
ACGTTGCCCATTTGATCGACAAGTGACAGACCTAGGAGATTCAGGTGTCTGGGGTTTGAAAAAA
AATTTTGCTTTACTGGAGCTTTTAGAACGTTTGCAAAATGGACATATTGGTCAGTATGGAGCTG
CAGAAGAAGCCCTTGGGATATCTGGAGAGAGTATCATTCGCTGTGATGAAGATGAAGCTCACGT
TGCATCTGTGTACTGCACTGTGTGTGCGACTCACTTGTGCTCAGAGTGTTCTCAAGTCACACAT
TCTACAAAGACACTGGCCAAGCATAGGCGAGTGCCTCTAGCTGATAAACCTCATGAGAAGACCA
TGTGCTGTCAGCACCAGCACTCAGTACTGGAGCCAGAAGCTAACCAGATCCGAGCGTCAATTTT
AGACATGGCTCACTGCATACGAACCTTCACTGAGGAGATCTCAGATTATTCCAGAAAATTAGTT
GGGATTGTTCAGCACATTGAAGGAGGAGAACAAATAGTGGAAGATGGAATTGGAATGGCTCACA
CGGAACACGTCCCAGGTACTGCAGAGAATGCACGATCATGTGTCAGAGCTTATTTTTCTGATTT
GCATGAAACTCTTTGTCGTCAAGAAGAAATGGCTCTCAGTGTTGTTGATGCCCATGTTCGAGAA
AAACTGATTTGGCTTAGGCAGCAACAAGAGGATATGACTATTCTCTTGTCCCAGGTTTCAACAG
CCTGTCTCCATTGTGAAAAGACTTTGCAGCAGGATGATTGCAGAGTTGTCTTGGCAAAACAAGA
AATCACAAGATTATTAGAAACACTGCAGAAACAGCAGCAGCAGTTTACAGAAGTTGCAGATCAT
ATTCAGTTGGATGCCAGTATTCCAGTCACTTTTACAAAGGACAACAGAGTTCATATTGGACCCA
AAATGGAAATCCGAGTAGTCACATTAGGATTAGATGGTGCTGGAAAAACTACTATTTTGTTCAA
GTTAAAACAAGATGAATTTATGCAGCCTATTCCAACAATTGGTTTTAATGTGGAAACTGTGGAA
TACAAAAATCTAAAATTCACCATTTGGGATGTGGGTGGAAAACACAAATTAAGACCATTGTGGA
AACATTATTACCTCAATACACAAGCTGTTGTATTTGTTGTTGACAGCAGTCACAGAGACAGAAT
TAGTGAAGCACACAGTGAACTTGCGAAGTTGTTAACAGAAAAAGAACTTCGAGATGCCTTACTC
TTGATTTTTGCTAACAAACAGGATGTCGCTGGGGCACTTTCGGTTGAAGAAATCACCGAACTTC
TCAGTCTCCATAAATTATGCTGCGGAAGGAGCTGGTATATTCAGGGCTGTGATGCTCGAAGTGG
TATGGGGCTCTACGAAGGGTTGGACTGGCTGTCCCGGCAACTTGTGGCTGCCGGAGTGTTGGAT
GTTGCTTGATTCTATTGCAGCAGTTGTTTCGAGCTTATGGTTAAAAGTTACTTTGCATGTAATG
CATTCTAAGAAATTCTACATCTCAAGTATGATAATTTAGTATGTGTACGTATGAATCCTGGACT
GAGAAATGTACCATTGCTTTTAAAAATTATTCTGTGGCAAATTTAAGTGATCCTGTTACATTGG
TTAAATAGTTTTGCTTTTGTTTTTTTTTGGATATAAACTTTTAAAAGGTACATTAGGCATTGGA
AACTTTGTACACTTTGTGTATGACCTGTACATTGGGAGAGAAGTGGCCACAGAGAATGAGTAGA
AGCTCCTTTATTTTATTGAAAAAATAGGCAGTGGAGTGCCTAACAGAACTTATGGAAACATGGC
TTCTTTACCCCTCCTTTTTACTCATTGTTGGCAGTCGTGGACTAGAATTTAAGCTGTACTGGGG
TAACAGGATTACCTGACTTTCACATTCAGCATAACATCTATTAGTGCTGGGGACCATCAAATAC
AGAAAATCAGGGTTTTTTTCCCCTACAGTTTTATTATAACGCTCTCCTAAAGCATTCTGCATAA
CGCACAATGAGAATGAATGTTATCTAAGTGGACCTGAGCATTAGACCCGAACTAAATTACGAAC
AATAGAACTGTGAAAGTTGTTTGATCTTCACTCATAAAAACCATTTCTAGGACTGGGCCTAGGT
TTATTTCCTAGGTCAAAGCCCTAAATTGGTCCTTTCGTTCACACTTACTTAGGCTAAGTAATAG
TGCATCCTCTGTTGGTAAAGTGCCACAAGTCACATGAAGAACCAGTCACCTTTACATAAACACA
CAGAGACCTAAATAGAAAACGGCCTAGACCTTAGGAAAGGTTTTCACACAGTGGGGAATGCTAA
TTTCTTTAACATGGTTCCCAAGTTAAGTGCATTTACTAGACTATAAAAAAGATCAAGGCTCTTT
AGGACAAGGTCTCAGTTAAAAGGAAGAACACATCTAAAGTAAAAGAAACTTAAAAAGTTTACAT
TTATTACGGGAGTGTTATGAATAAAAGTTAAATTTTGTGTTCTCTATAGTTTCTTATTTGTAAG
ATACTCTTATTATGGAAGCATGATTTCTTATATTTAAATAGGTAGATTTCTTGTTATTAATGCT
TTCACTTTAGGATGAAGTTGAGAGCTAAATCTTAGTGCAATTGTTAAAAGGACAGTGATGTCTG
ACAATAGGATGTGATTTTTAGGTGGCAATGTTCTGGTTCAGTTTTTCTCAAATAACCCTTTTTT
TTAACTTAGAAAACAGCACTACAAAAAGTCCATCGAACATTATGGGCAACATGTAAATAAAAAT
ATAATAATTTTCCCTTTTTCAAGAGTGTAACAACACGCTGTTACACATAGCTTGTGTGCATATG
TAATACACTGTAATTAAATTATTTAATTTTGACTGATTTTAGTAACTGTGAAAAATAAAGACGT
TGCGTTTATTTGTGA

hide sequence

RefSeq Acc Id:

XM_063282615 ⟹ XP_063138685

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	37,036,194 - 37,069,022 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001094107	(Get FASTA)	NCBI Sequence Viewer
	XP_008758905	(Get FASTA)	NCBI Sequence Viewer
	XP_008758906	(Get FASTA)	NCBI Sequence Viewer
	XP_063138685	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41301	(Get FASTA)	NCBI Sequence Viewer
	EDM10262	(Get FASTA)	NCBI Sequence Viewer
	EDM10263	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000016597
	ENSRNOP00000016597.7
	ENSRNOP00000016647
	ENSRNOP00000016647.5
	ENSRNOP00000088434.1
GenBank Protein	P36407	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001094107 ⟸ NM_001100637

- UniProtKB:

D3ZT39 (UniProtKB/Swiss-Prot), P36407 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAALAVNKPGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLSRLP
LHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGHIGQYGAAEEALGISGESIIRCD
EDEAHVASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCCQHQVHAIEFVCLE
EACQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQ
HIEGGEQIVEDGIGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIW
LRQQQEDMTILLSQVSTACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLD
ASIPVTFTKDNRVYIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNL
KFTIWDVGEKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFA
NKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA

hide sequence

RefSeq Acc Id:	XP_008758905 ⟸ XM_008760683
- Peptide Label:	isoform X1
- UniProtKB:	P36407 (UniProtKB/Swiss-Prot), D3ZT39 (UniProtKB/Swiss-Prot), F1LSC5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAALAVNKPGAGVDSGRQGSRGTAVVKTIHEILAHGPECQSEPVLAAFLPHYLSVLECGVCEDV FSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLER LQNGHIGQYGAAEEALGISGESIIRCDEDEAHVASVYCTVCATHLCSECSQVTHSTKTLAKHRR VPLADKPHEKTMCCQHQVHAIEFVCLEEACQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRAS ILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCVRAYFS DLHETLCRQEEMALSVVDAHVREKLIWLRQQQEDMTILLSQVSTACLHCEKTLQQDDCRVVLAK QEITRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTIL FKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRD RISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDAR SGMGLYEGLDWLSRQLVAAGVLDVA hide sequence

RefSeq Acc Id:	XP_008758906 ⟸ XM_008760684
- Peptide Label:	isoform X2
- UniProtKB:	P36407 (UniProtKB/Swiss-Prot), D3ZT39 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAALAVNKPGAGVDSGRQGSRGTAVVKTIHEILAHGPECQSEPVLAAFLPHYLSVLECGVCEDV FSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLER LQNGHIGQYGAAEEALGISGESIIRCDEDEAHVASVYCTVCATHLCSECSQVTHSTKTLAKHRR VPLADKPHEKTMCCQHQHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGE QIVEDGIGMAHTEHVPGTAENARSCVRAYFSDLHETLCRQEEMALSVVDAHVREKLIWLRQQQE DMTILLSQVSTACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLDASIPVT FTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWD VGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVA GALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA hide sequence

RefSeq Acc Id:

ENSRNOP00000016597 ⟸ ENSRNOT00000016596

RefSeq Acc Id:

ENSRNOP00000016647 ⟸ ENSRNOT00000016649

RefSeq Acc Id:

ENSRNOP00000088434 ⟸ ENSRNOT00000106700

RefSeq Acc Id:	XP_063138685 ⟸ XM_063282615
- Peptide Label:	isoform X3

Protein Domains

B box-type C2H2-type RING-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P36407-F1-model_v2	AlphaFold	P36407	1-573	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691125

Promoter ID:

EPDNEW_R1646

Type:

initiation region

Name:

Trim23_1

Description:

tripartite motif-containing 23

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	34,255,352 - 34,255,412	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621587	AgrOrtholog
BioCyc Gene	G2FUF-54554	BioCyc
Ensembl Genes	ENSRNOG00000012354	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000016596	ENTREZGENE
	ENSRNOT00000016596.7	UniProtKB/TrEMBL
	ENSRNOT00000016649.7	UniProtKB/TrEMBL
	ENSRNOT00000106700.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Bbox_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Small_GTPase_ARF/SAR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf-RING_LisH	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_B-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:81002	UniProtKB/Swiss-Prot
NCBI Gene	81002	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE TRIM23	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN CBG20824	UniProtKB/TrEMBL
	PTHR11711	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RING-TYPE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Arf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-B_box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	zf-RING_UBOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Trim23	PhenoGen
PRINTS	SAR1GTPBP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ARF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_BBOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000012354	RatGTEx
SMART	ARF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BBC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	BBOX	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RAB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	B-box zinc-binding domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RING/U-box	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6AIW0_RAT	UniProtKB/TrEMBL
	A6I5F4_RAT	UniProtKB/TrEMBL
	A6I5F5_RAT	UniProtKB/TrEMBL
	D3ZT39	ENTREZGENE
	F1LSC5	ENTREZGENE, UniProtKB/TrEMBL
	H9KVE7_RAT	UniProtKB/TrEMBL
	P36407	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	D3ZT39	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-24	Trim23	tripartite motif-containing 23	Trim23	tripartite motif protein 23	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-12-14	Trim23	tripartite motif protein 23	Arfd1	ADP-ribosylation factor domain protein 1, 64kD	Symbol and Name updated	1299863	APPROVED
2002-08-07	Arfd1				Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a ADP-ribosylation factor (ARF) domain	727255
gene_homology	96% amino acid identity to human homolog	727255
gene_protein	64 kDa	727255

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar