Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Burkitt lymphoma | | ISO | A4GALT (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:11482875 | |
|
Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Burkitt lymphoma | | ISO | A4GALT (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:11482875 | |
|
|
|
|
|
|
|
# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of alpha 1, 4-glycosyltransferases conserved in plants, insects, and mammals. | Keusch JJ, etal., J Biol Chem 2000 Aug 18;275(33):25315-21. |
4. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
5. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
6. | GOA pipeline | RGD automated data pipeline |
7. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
9. | The P blood group system: biochemical, serological, and clinical aspects. | Spitalnik PF and Spitalnik SL, Transfus Med Rev 1995 Apr;9(2):110-22. |
PMID:10747952 | PMID:10748143 | PMID:12477932 | PMID:16476743 | PMID:22875802 | PMID:23376485 |
A4galt (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4GALT (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4galt (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4galt (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4GALT (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4GALT (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4galt (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4GALT (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4GALT (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A4galt (Heterocephalus glaber - naked mole-rat) |
|
.
Variants in A4galt
130 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH131730 |
|
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 12 | 32 | 5 | |||||||||
Low | 20 | 11 | 2 | 11 | 2 | 8 | 3 | 24 | 1 | ||||
Below cutoff | 10 | 15 | 8 | 8 | 8 | 5 | 7 | 52 | 8 | 9 | 5 |
RefSeq Transcripts | NM_022240 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006242117 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006242118 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017595078 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017595079 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017595081 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC135486 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AF248544 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC097323 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473950 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000007 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000012914 ⟹ ENSRNOP00000064362 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000096640 ⟹ ENSRNOP00000095592 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000104849 ⟹ ENSRNOP00000084868 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000108253 ⟹ ENSRNOP00000081935 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | NM_022240 ⟹ NP_071576 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
|
||||||||||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006242117 ⟹ XP_006242179 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006242118 ⟹ XP_006242180 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_017595081 ⟹ XP_017450570 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
|
||||||||||||||||
Sequence: |
Protein RefSeqs | NP_071576 | (Get FASTA) | NCBI Sequence Viewer |
XP_006242179 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006242180 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017450570 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAF82758 | (Get FASTA) | NCBI Sequence Viewer |
AAH97323 | (Get FASTA) | NCBI Sequence Viewer | |
EDM15634 | (Get FASTA) | NCBI Sequence Viewer | |
EDM15635 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000064362.1 | ||
ENSRNOP00000081935 | |||
ENSRNOP00000081935.1 | |||
ENSRNOP00000084868.1 | |||
ENSRNOP00000095592 | |||
ENSRNOP00000095592.1 | |||
ENSRNOP00055044706 | |||
ENSRNOP00055044712 | |||
ENSRNOP00055044713 | |||
ENSRNOP00055044714 | |||
ENSRNOP00060044364 | |||
ENSRNOP00060044373 | |||
ENSRNOP00060044377 | |||
ENSRNOP00060044378 | |||
ENSRNOP00065046880 | |||
ENSRNOP00065046885 | |||
ENSRNOP00065046889 | |||
ENSRNOP00065046892 | |||
GenBank Protein | Q9JI93 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_071576 ⟸ NM_022240 |
- UniProtKB: | Q4QR98 (UniProtKB/Swiss-Prot), Q9JI93 (UniProtKB/Swiss-Prot), A6HT88 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006242179 ⟸ XM_006242117 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q4QR98 (UniProtKB/Swiss-Prot), Q9JI93 (UniProtKB/Swiss-Prot), A6HT88 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006242180 ⟸ XM_006242118 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q4QR98 (UniProtKB/Swiss-Prot), Q9JI93 (UniProtKB/Swiss-Prot), A6HT88 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017450570 ⟸ XM_017595081 |
- Peptide Label: | isoform X1 |
- UniProtKB: | Q4QR98 (UniProtKB/Swiss-Prot), Q9JI93 (UniProtKB/Swiss-Prot), A6HT88 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000064362 ⟸ ENSRNOT00000012914 |
RefSeq Acc Id: | ENSRNOP00000081935 ⟸ ENSRNOT00000108253 |
RefSeq Acc Id: | ENSRNOP00000095592 ⟸ ENSRNOT00000096640 |
RefSeq Acc Id: | ENSRNOP00000084868 ⟸ ENSRNOT00000104849 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9JI93-F1-model_v2 | AlphaFold | Q9JI93 | 1-360 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:621583 | AgrOrtholog |
BioCyc Gene | G2FUF-32606 | BioCyc |
BioCyc Pathway | PWY-7838 [globo-series glycosphingolipids biosynthesis] | BioCyc |
BioCyc Pathway Image | PWY-7838 | BioCyc |
Ensembl Genes | ENSRNOG00000009736 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
ENSRNOG00055031189 | UniProtKB/Swiss-Prot | |
ENSRNOG00060030725 | UniProtKB/Swiss-Prot | |
ENSRNOG00065033099 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000012914.6 | UniProtKB/Swiss-Prot |
ENSRNOT00000096640.1 | UniProtKB/Swiss-Prot | |
ENSRNOT00000104849.1 | UniProtKB/Swiss-Prot | |
ENSRNOT00000108253.1 | UniProtKB/Swiss-Prot | |
ENSRNOT00055054040 | UniProtKB/Swiss-Prot | |
ENSRNOT00055054051 | UniProtKB/Swiss-Prot | |
ENSRNOT00055054056 | UniProtKB/Swiss-Prot | |
ENSRNOT00055054060 | UniProtKB/Swiss-Prot | |
ENSRNOT00060053385 | UniProtKB/Swiss-Prot | |
ENSRNOT00060053401 | UniProtKB/Swiss-Prot | |
ENSRNOT00060053407 | UniProtKB/Swiss-Prot | |
ENSRNOT00060053410 | UniProtKB/Swiss-Prot | |
ENSRNOT00065056939 | UniProtKB/Swiss-Prot | |
ENSRNOT00065056944 | UniProtKB/Swiss-Prot | |
ENSRNOT00065056948 | UniProtKB/Swiss-Prot | |
ENSRNOT00065056951 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 3.90.550.20 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:7459302 | IMAGE-MGC_LOAD |
InterPro | A1-4-GlycosylTfrase_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
GlycoTrfase_DXD_sugar-bd_CS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Nucleotide-diphossugar_trans | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:63888 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MGC_CLONE | MGC:114326 | IMAGE-MGC_LOAD |
NCBI Gene | 63888 | ENTREZGENE |
PANTHER | LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Gb3_synth | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Gly_transf_sug | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | A4galt | PhenoGen |
RatGTEx | ENSRNOG00000009736 | RatGTEx |
ENSRNOG00055031189 | RatGTEx | |
ENSRNOG00060030725 | RatGTEx | |
ENSRNOG00065033099 | RatGTEx | |
Superfamily-SCOP | Nucleotide-diphospho-sugar transferases | UniProtKB/TrEMBL, UniProtKB/Swiss-Prot |
UniProt | A4GAT_RAT | UniProtKB/Swiss-Prot |
A6HT88 | ENTREZGENE, UniProtKB/TrEMBL | |
Q4QR98 | ENTREZGENE | |
Q9JI93 | ENTREZGENE | |
UniProt Secondary | Q4QR98 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2023-12-29 | A4galt | alpha 1,4-galactosyltransferase | A4galt | alpha 1,4-galactosyltransferase (P blood group) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2019-04-01 | A4galt | alpha 1,4-galactosyltransferase (P blood group) | A4galt | alpha 1,4-galactosyltransferase | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2004-09-10 | A4galt | alpha 1,4-galactosyltransferase | Gb3 | Gb3 synthase | Symbol and Name updated | 1299863 | APPROVED |
2002-08-07 | Gb3 | Gb3 synthase | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
---|---|---|
gene_expression | expressed in kidney, mesenteric lymph node, spleen, and brain | 632742 |
gene_protein | type II transmembrane glycosyltransferase of 360 amino acids | 632742 |