Chrnb3 (cholinergic receptor nicotinic beta 3 subunit) - Rat Genome Database

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Gene: Chrnb3 (cholinergic receptor nicotinic beta 3 subunit) Rattus norvegicus
Analyze
Symbol: Chrnb3
Name: cholinergic receptor nicotinic beta 3 subunit
RGD ID: 621544
Description: Enables acetylcholine binding activity. Contributes to heterocyclic compound binding activity. Predicted to be involved in several processes, including presynaptic modulation of chemical synaptic transmission; response to nicotine; and synaptic signaling. Part of acetylcholine-gated channel complex. Biomarker of depressive disorder. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human CHRNB3 (cholinergic receptor nicotinic beta 3 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-nicotine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cholinergic receptor, nicotinic beta 3; cholinergic receptor, nicotinic, beta 3; cholinergic receptor, nicotinic, beta 3 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 3; neuronal acetylcholine receptor subunit beta-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81671,411,847 - 71,454,225 (-)NCBIGRCr8
mRatBN7.21664,713,438 - 64,751,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1664,714,169 - 64,751,360 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1670,005,948 - 70,034,159 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01673,412,292 - 73,440,503 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01668,649,563 - 68,686,751 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01668,876,442 - 68,913,628 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1668,875,709 - 68,913,628 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01668,502,911 - 68,539,031 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,028,625 - 69,069,274 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11669,028,830 - 69,069,480 (-)NCBI
Celera1662,637,536 - 62,674,782 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mammalian nicotinic acetylcholine receptors: from structure to function. Albuquerque EX, etal., Physiol Rev. 2009 Jan;89(1):73-120. doi: 10.1152/physrev.00015.2008.
2. Beta 3: a new member of nicotinic acetylcholine receptor gene family is expressed in brain. Deneris ES, etal., J Biol Chem 1989 Apr 15;264(11):6268-72.
3. Formation of oligomers containing the beta3 and beta4 subunits of the rat nicotinic receptor. Forsayeth JR and Kobrin E, J Neurosci. 1997 Mar 1;17(5):1531-8.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Han S, etal., Sci Rep. 2017 Apr 18;7(1):900. doi: 10.1038/s41598-017-01088-6.
6. Nicotinic cholinergic receptors in the rat retina: simple and mixed heteromeric subtypes. Marritt AM, etal., Mol Pharmacol. 2005 Dec;68(6):1656-68. Epub 2005 Aug 29.
7. Expression of acetylcholine receptors by experimental rat renal allografts. Meixner M, etal., Biomed Res Int. 2014;2014:289656. doi: 10.1155/2014/289656. Epub 2014 Jul 9.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14657161   PMID:18266937   PMID:23846688   PMID:24398291  


Genomics

Comparative Map Data
Chrnb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81671,411,847 - 71,454,225 (-)NCBIGRCr8
mRatBN7.21664,713,438 - 64,751,360 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1664,714,169 - 64,751,360 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1670,005,948 - 70,034,159 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01673,412,292 - 73,440,503 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01668,649,563 - 68,686,751 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01668,876,442 - 68,913,628 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1668,875,709 - 68,913,628 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01668,502,911 - 68,539,031 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,028,625 - 69,069,274 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11669,028,830 - 69,069,480 (-)NCBI
Celera1662,637,536 - 62,674,782 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
CHRNB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38842,697,366 - 42,737,407 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl842,697,366 - 42,737,407 (+)EnsemblGRCh38hg38GRCh38
GRCh37842,552,509 - 42,592,550 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36842,671,719 - 42,711,366 (+)NCBINCBI36Build 36hg18NCBI36
Build 34842,671,718 - 42,711,366NCBI
Celera841,499,567 - 41,540,205 (+)NCBICelera
Cytogenetic Map8p11.21NCBI
HuRef841,074,730 - 41,114,440 (+)NCBIHuRef
CHM1_1842,599,470 - 42,639,116 (+)NCBICHM1_1
T2T-CHM13v2.0842,965,410 - 43,005,503 (+)NCBIT2T-CHM13v2.0
Chrnb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39827,858,688 - 27,889,758 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl827,858,739 - 27,889,758 (+)EnsemblGRCm39 Ensembl
GRCm38827,368,711 - 27,399,730 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl827,368,711 - 27,399,730 (+)EnsemblGRCm38mm10GRCm38
MGSCv37828,479,183 - 28,510,202 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36828,834,647 - 28,865,665 (+)NCBIMGSCv36mm8
Celera828,858,231 - 28,889,248 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map816.0NCBI
Chrnb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955536190,949 - 232,424 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955536189,881 - 229,835 (-)NCBIChiLan1.0ChiLan1.0
CHRNB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2761,155,811 - 61,195,012 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1836,871,869 - 36,911,058 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0841,947,062 - 41,987,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1839,390,959 - 39,430,267 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl839,391,001 - 39,429,926 (+)Ensemblpanpan1.1panPan2
CHRNB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11623,021,652 - 23,040,907 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1623,021,645 - 23,048,347 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1623,524,646 - 23,545,471 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01624,771,003 - 24,791,610 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1624,772,988 - 24,791,545 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11623,139,564 - 23,160,813 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01623,704,601 - 23,725,844 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01623,755,352 - 23,776,571 (-)NCBIUU_Cfam_GSD_1.0
Chrnb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494346,089,677 - 46,116,077 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493678546,796 - 72,640 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493678546,076 - 72,529 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRNB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1711,687,557 - 11,722,183 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11711,687,646 - 11,714,357 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21712,667,001 - 12,693,124 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRNB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1840,695,061 - 40,730,127 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl840,706,666 - 40,728,963 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660521,043,203 - 1,065,050 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chrnb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624780487,006 - 510,056 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624780481,836 - 510,192 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chrnb3
396 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:107
Count of miRNA genes:96
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000016656
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70215Niddm29Non-insulin dependent diabetes mellitus QTL 293.54blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)161900443575226532Rat
2302057Pia29Pristane induced arthritis QTL 293.60.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)162173597566735975Rat
8694453Bw172Body weight QTL 1728.330.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)162432551369325513Rat
6903294Stl30Serum triglyceride level QTL 302.60.0013blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)162515279370152793Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat

Markers in Region
PMC18423P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21664,718,406 - 64,719,062 (+)MAPPERmRatBN7.2
Rnor_6.01668,880,679 - 68,881,334NCBIRnor6.0
Rnor_5.01668,507,148 - 68,507,803UniSTSRnor5.0
RGSC_v3.41669,032,862 - 69,033,517UniSTSRGSC3.4
Celera1662,641,773 - 62,642,428UniSTS
Cytogenetic Map16q12.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 5
Low 37 3
Below cutoff 1 5 3 2 3 3 17 8 17 9 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016656   ⟹   ENSRNOP00000016656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1664,714,169 - 64,751,360 (-)Ensembl
Rnor_6.0 Ensembl1668,875,709 - 68,913,628 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110724   ⟹   ENSRNOP00000086782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1664,714,169 - 64,751,360 (-)Ensembl
RefSeq Acc Id: NM_133597   ⟹   NP_598281
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81671,417,039 - 71,454,225 (-)NCBI
mRatBN7.21664,714,169 - 64,751,360 (-)NCBI
Rnor_6.01668,876,442 - 68,913,628 (-)NCBI
Rnor_5.01668,502,911 - 68,539,031 (-)NCBI
RGSC_v3.41669,028,625 - 69,069,274 (-)RGD
Celera1662,637,536 - 62,674,782 (-)RGD
Sequence:
RefSeq Acc Id: XM_039094178   ⟹   XP_038950106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81671,411,847 - 71,438,853 (-)NCBI
mRatBN7.21664,713,438 - 64,736,011 (-)NCBI
RefSeq Acc Id: XM_039094179   ⟹   XP_038950107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81671,411,847 - 71,441,648 (-)NCBI
mRatBN7.21664,713,438 - 64,738,736 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_598281   ⟸   NM_133597
- Peptide Label: precursor
- UniProtKB: P12391 (UniProtKB/Swiss-Prot),   A6IVW9 (UniProtKB/TrEMBL),   Q6PW48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016656   ⟸   ENSRNOT00000016656
RefSeq Acc Id: XP_038950107   ⟸   XM_039094179
- Peptide Label: isoform X1
- UniProtKB: Q6PW48 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950106   ⟸   XM_039094178
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000086782   ⟸   ENSRNOT00000110724
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P12391-F1-model_v2 AlphaFold P12391 1-464 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621544 AgrOrtholog
BioCyc Gene G2FUF-11040 BioCyc
Ensembl Genes ENSRNOG00000012448 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055007994 UniProtKB/Swiss-Prot
  ENSRNOG00060012244 UniProtKB/Swiss-Prot
  ENSRNOG00065002722 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016656 ENTREZGENE
  ENSRNOT00000016656.5 UniProtKB/Swiss-Prot
  ENSRNOT00000110724.1 UniProtKB/TrEMBL
  ENSRNOT00055013476 UniProtKB/Swiss-Prot
  ENSRNOT00060020760 UniProtKB/Swiss-Prot
  ENSRNOT00065003705 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Neur_chan_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nicotinic_acetylcholine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171131 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 171131 ENTREZGENE
PANTHER NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18945 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Chrnb3 PhenoGen
PRINTS NICOTINICR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012448 RatGTEx
  ENSRNOG00055007994 RatGTEx
  ENSRNOG00060012244 RatGTEx
  ENSRNOG00065002722 RatGTEx
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A6P7_RAT UniProtKB/TrEMBL
  A6IVW9 ENTREZGENE, UniProtKB/TrEMBL
  ACHB3_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6PW48 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-11 Chrnb3  cholinergic receptor nicotinic beta 3 subunit  Chrnb3  cholinergic receptor, nicotinic beta 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-09 Chrnb3  cholinergic receptor, nicotinic beta 3  Chrnb3  cholinergic receptor, nicotinic, beta 3 (neuronal)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-16 Chrnb3  cholinergic receptor, nicotinic, beta 3 (neuronal)  Chrnb3  cholinergic receptor, nicotinic, beta 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-29 Chrnb3  cholinergic receptor, nicotinic, beta 3  Chrnb3  cholinergic receptor, nicotinic, beta polypeptide 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Chrnb3  cholinergic receptor, nicotinic, beta polypeptide 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Chrnb3  cholinergic receptor, nicotinic, beta polypeptide 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain 724745