Gene: Kcnk6 (potassium two pore domain channel subfamily K member 6) Rattus norvegicus
Analyze
Symbol:
Kcnk6
Name:
potassium two pore domain channel subfamily K member 6
RGD ID:
621450
Description:
Enables potassium channel activity. Involved in regulation of lysosome size. Located in late endosome membrane and lysosomal membrane. Biomarker of brain infarction. Orthologous to human KCNK6 (potassium two pore domain channel subfamily K member 6); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
LOC100909725; potassium channel subfamily K member 6; potassium channel subfamily K member 6 (TWIK-2); potassium channel subfamily K member 6-like; potassium channel, subfamily K, member 6; potassium channel, subfamily K, member 6 (TWIK-2); potassium channel, two pore domain subfamily K, member 6; potassium inwardly-rectifying channel, subfamily K, member 6; Twik-2; Twik2
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
KCNK6 (potassium two pore domain channel subfamily K member 6)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):
Kcnk6 (potassium inwardly-rectifying channel, subfamily K, member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Kcnk6 (potassium two pore domain channel subfamily K member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
KCNK6 (potassium two pore domain channel subfamily K member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
KCNK6 (potassium two pore domain channel subfamily K member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Kcnk6 (potassium two pore domain channel subfamily K member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
KCNK6 (potassium two pore domain channel subfamily K member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
KCNK6 (potassium two pore domain channel subfamily K member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Kcnk6 (potassium two pore domain channel subfamily K member 6)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
KCNK6 (potassium two pore domain channel subfamily K member 6)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Kcnk6 (potassium inwardly-rectifying channel, subfamily K, member 6)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
kcnk6 (potassium channel, subfamily K, member 6)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG1688
Alliance
DIOPT (InParanoid|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
TOK1
Alliance
DIOPT (Ensembl Compara|PANTHER|SonicParanoid)
Caenorhabditis elegans (roundworm):
twk-46
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
kcnk6
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER|PhylomeDB)
Latest Assembly:
mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 93,652,888 - 93,661,419 (-) NCBI GRCr8 mRatBN7.2 1 84,525,613 - 84,533,948 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 84,525,590 - 84,534,677 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 89,937,040 - 89,945,285 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 98,396,659 - 98,404,888 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 91,692,885 - 91,701,131 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 88,168,438 - 88,176,610 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 88,169,378 - 88,176,610 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 87,166,109 - 87,174,821 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 89,343,864 - 89,352,036 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 84,359,738 - 84,367,910 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 84,404,339 - 84,446,021 (-) NCBI Celera 1 78,912,886 - 78,921,054 (-) NCBI Celera Cytogenetic Map 1 q21 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Kcnk6 Rat 1,2-dimethylhydrazine decreases expression ISO Kcnk6 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of KCNK6 mRNA CTD PMID:22206623 Kcnk6 Rat 1,2-dimethylhydrazine multiple interactions ISO Kcnk6 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KCNK6 mRNA CTD PMID:22206623 Kcnk6 Rat 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of KCNK6 mRNA CTD PMID:21983209 Kcnk6 Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of KCNK6 mRNA CTD PMID:17557909 Kcnk6 Rat 17beta-estradiol multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of KCNK6 mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of KCNK6 mRNA CTD PMID:20404318 and PMID:30165855 Kcnk6 Rat 17beta-estradiol increases expression ISO KCNK6 (Homo sapiens) 6480464 Estradiol results in increased expression of KCNK6 mRNA CTD PMID:31614463 Kcnk6 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Kcnk6 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of KCNK6 mRNA CTD PMID:19933214 Kcnk6 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of KCNK6 mRNA CTD PMID:33387578 Kcnk6 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Kcnk6 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of KCNK6 mRNA CTD PMID:21570461 Kcnk6 Rat 4,4'-sulfonyldiphenol increases expression ISO Kcnk6 (Mus musculus) 6480464 bisphenol S results in increased expression of KCNK6 mRNA CTD PMID:30951980 Kcnk6 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of KCNK6 mRNA CTD PMID:24780913 Kcnk6 Rat actinomycin D multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of KCNK6 mRNA CTD PMID:38460933 Kcnk6 Rat actinomycin D increases expression ISO KCNK6 (Homo sapiens) 6480464 Dactinomycin results in increased expression of KCNK6 mRNA CTD PMID:38460933 Kcnk6 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of KCNK6 mRNA CTD PMID:16483693 Kcnk6 Rat aristolochic acid A increases expression ISO KCNK6 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of KCNK6 mRNA CTD PMID:33212167 Kcnk6 Rat arsenous acid decreases expression ISO KCNK6 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of KCNK6 mRNA CTD PMID:22521957 Kcnk6 Rat benzo[a]pyrene multiple interactions ISO Kcnk6 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to KCNK6 promoter] CTD PMID:19654925 Kcnk6 Rat benzo[a]pyrene increases expression ISO KCNK6 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of KCNK6 mRNA CTD PMID:32234424 Kcnk6 Rat benzo[a]pyrene decreases methylation ISO KCNK6 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of KCNK6 promoter CTD PMID:27901495 Kcnk6 Rat bis(2-ethylhexyl) phthalate increases expression ISO KCNK6 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of KCNK6 mRNA CTD PMID:31163220 Kcnk6 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of KCNK6 mRNA CTD PMID:25181051 Kcnk6 Rat bisphenol A increases expression ISO KCNK6 (Homo sapiens) 6480464 bisphenol A results in increased expression of KCNK6 mRNA CTD PMID:32387340 Kcnk6 Rat Bisphenol B increases expression ISO KCNK6 (Homo sapiens) 6480464 bisphenol B results in increased expression of KCNK6 mRNA CTD PMID:32387340 Kcnk6 Rat camptothecin increases expression ISO KCNK6 (Homo sapiens) 6480464 Camptothecin results in increased expression of KCNK6 mRNA CTD PMID:38460933 Kcnk6 Rat cyclosporin A increases expression ISO KCNK6 (Homo sapiens) 6480464 Cyclosporine results in increased expression of KCNK6 mRNA CTD PMID:27989131 Kcnk6 Rat diarsenic trioxide decreases expression ISO KCNK6 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of KCNK6 mRNA CTD PMID:22521957 Kcnk6 Rat Dibutyl phosphate affects expression ISO KCNK6 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of KCNK6 mRNA CTD PMID:37042841 Kcnk6 Rat dibutyl phthalate increases expression ISO Kcnk6 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of KCNK6 mRNA CTD PMID:17361019 and PMID:21266533 Kcnk6 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of KCNK6 mRNA CTD PMID:21266533 Kcnk6 Rat dimethylarsinic acid multiple interactions ISO Kcnk6 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of KCNK6 mRNA CTD PMID:34876320 Kcnk6 Rat dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of KCNK6 mRNA CTD PMID:33729688 Kcnk6 Rat dorsomorphin multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Kcnk6 Rat doxorubicin decreases expression ISO KCNK6 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of KCNK6 mRNA CTD PMID:29803840 Kcnk6 Rat entinostat increases expression ISO KCNK6 (Homo sapiens) 6480464 entinostat results in increased expression of KCNK6 mRNA CTD PMID:26272509 and PMID:27188386 Kcnk6 Rat entinostat multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KCNK6 mRNA CTD PMID:27188386 Kcnk6 Rat folic acid multiple interactions ISO Kcnk6 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of KCNK6 mRNA CTD PMID:22206623 Kcnk6 Rat furan decreases methylation EXP 6480464 furan results in decreased methylation of KCNK6 gene CTD PMID:27387713 Kcnk6 Rat furan increases expression EXP 6480464 furan results in increased expression of KCNK6 mRNA CTD PMID:27387713 Kcnk6 Rat lithium chloride increases expression ISO KCNK6 (Homo sapiens) 6480464 Lithium Chloride results in increased expression of KCNK6 mRNA CTD PMID:23527032 Kcnk6 Rat methylarsonic acid multiple interactions ISO Kcnk6 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of KCNK6 mRNA CTD PMID:34876320 Kcnk6 Rat mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of KCNK6 mRNA CTD PMID:16809437 Kcnk6 Rat N-methyl-4-phenylpyridinium increases expression ISO KCNK6 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of KCNK6 mRNA CTD PMID:24810058 Kcnk6 Rat nickel atom increases expression ISO KCNK6 (Homo sapiens) 6480464 Nickel results in increased expression of KCNK6 mRNA CTD PMID:24768652 and PMID:25583101 Kcnk6 Rat nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of KCNK6 mRNA CTD PMID:33484710 Kcnk6 Rat Nutlin-3 multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of KCNK6 mRNA CTD PMID:38460933 Kcnk6 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of KCNK6 mRNA CTD PMID:33387578 Kcnk6 Rat perfluorooctanoic acid multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] results in decreased expression of KCNK6 mRNA CTD PMID:33325755 Kcnk6 Rat phenobarbital decreases expression ISO Kcnk6 (Mus musculus) 6480464 Phenobarbital results in decreased expression of KCNK6 mRNA CTD PMID:19482888 Kcnk6 Rat phenobarbital multiple interactions ISO Kcnk6 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of KCNK6 mRNA] CTD PMID:19482888 Kcnk6 Rat phytoestrogen multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [Plasticizers co-treated with Cosmetics co-treated with Flame Retardants co-treated with perfluorooctanoic acid co-treated with Phytoestrogens] results in decreased expression of KCNK6 mRNA CTD PMID:33325755 Kcnk6 Rat picene decreases expression ISO KCNK6 (Homo sapiens) 6480464 picene results in decreased expression of KCNK6 mRNA CTD PMID:32251684 Kcnk6 Rat progesterone increases expression ISO KCNK6 (Homo sapiens) 6480464 Progesterone results in increased expression of KCNK6 mRNA CTD PMID:20864642 Kcnk6 Rat propanal increases expression ISO KCNK6 (Homo sapiens) 6480464 propionaldehyde results in increased expression of KCNK6 mRNA CTD PMID:26079696 Kcnk6 Rat rotenone increases expression ISO Kcnk6 (Mus musculus) 6480464 Rotenone results in increased expression of KCNK6 mRNA CTD PMID:32937126 Kcnk6 Rat SB 431542 multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Kcnk6 Rat sodium arsenate multiple interactions ISO Kcnk6 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of KCNK6 mRNA CTD PMID:34876320 Kcnk6 Rat sodium arsenite multiple interactions ISO Kcnk6 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of KCNK6 mRNA CTD PMID:34876320 Kcnk6 Rat testosterone decreases expression ISO Kcnk6 (Mus musculus) 6480464 Testosterone deficiency results in decreased expression of KCNK6 mRNA CTD PMID:33848595 Kcnk6 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of KCNK6 mRNA CTD PMID:34492290 Kcnk6 Rat trichloroethene affects expression EXP 6480464 Trichloroethylene affects the expression of KCNK6 mRNA CTD PMID:33387578 Kcnk6 Rat trichostatin A increases expression ISO KCNK6 (Homo sapiens) 6480464 trichostatin A results in increased expression of KCNK6 mRNA CTD PMID:24935251 Kcnk6 Rat triclosan increases expression ISO KCNK6 (Homo sapiens) 6480464 Triclosan results in increased expression of KCNK6 mRNA CTD PMID:30510588 Kcnk6 Rat valproic acid increases methylation ISO KCNK6 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of KCNK6 gene CTD PMID:29154799 Kcnk6 Rat valproic acid affects expression ISO KCNK6 (Homo sapiens) 6480464 Valproic Acid affects the expression of KCNK6 mRNA CTD PMID:25979313 Kcnk6 Rat valproic acid increases expression ISO KCNK6 (Homo sapiens) 6480464 Valproic Acid results in increased expression of KCNK6 mRNA CTD PMID:23179753 more ... Kcnk6 Rat valproic acid multiple interactions ISO KCNK6 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KCNK6 mRNA CTD PMID:27188386
References
References - curated
#
Reference Title
Reference Citation
1.
Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.
Bobak N, etal., Sci Rep. 2017 Apr 5;7(1):649. doi: 10.1038/s41598-017-00640-8.
2.
Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke.
Buga AM, etal., PLoS One. 2012;7(12):e50985. doi: 10.1371/journal.pone.0050985. Epub 2012 Dec 12.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
5.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
6.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.
TWIK-2, an inactivating 2P domain K+ channel.
Patel AJ, etal., J Biol Chem 2000 Sep 15;275(37):28722-30.
8.
GOA pipeline
RGD automated data pipeline
9.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
Genomics
Comparative Map Data
Kcnk6 (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 93,652,888 - 93,661,419 (-) NCBI GRCr8 mRatBN7.2 1 84,525,613 - 84,533,948 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 84,525,590 - 84,534,677 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 89,937,040 - 89,945,285 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 98,396,659 - 98,404,888 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 91,692,885 - 91,701,131 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 88,168,438 - 88,176,610 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 88,169,378 - 88,176,610 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 87,166,109 - 87,174,821 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 89,343,864 - 89,352,036 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 84,359,738 - 84,367,910 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 84,404,339 - 84,446,021 (-) NCBI Celera 1 78,912,886 - 78,921,054 (-) NCBI Celera Cytogenetic Map 1 q21 NCBI
KCNK6 (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 38,319,845 - 38,332,076 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 38,319,845 - 38,332,076 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 38,810,485 - 38,822,716 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 43,502,322 - 43,511,494 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 43,502,323 - 43,511,487 NCBI Celera 19 35,612,720 - 35,621,891 (+) NCBI Celera Cytogenetic Map 19 q13.2 NCBI HuRef 19 35,258,112 - 35,267,183 (+) NCBI HuRef CHM1_1 19 38,810,843 - 38,820,013 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 41,122,020 - 41,134,251 (+) NCBI T2T-CHM13v2.0
Kcnk6 (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 28,921,353 - 28,931,947 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 28,921,351 - 28,931,940 (-) Ensembl GRCm39 Ensembl GRCm38 7 29,221,928 - 29,232,522 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 29,221,926 - 29,232,515 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 30,006,947 - 30,017,541 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 7 28,930,688 - 28,941,253 (-) NCBI MGSCv36 mm8 Celera 7 23,793,186 - 23,803,782 (-) NCBI Celera Cytogenetic Map 7 B1 NCBI cM Map 7 16.94 NCBI
Kcnk6 (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955468 1,108,025 - 1,117,366 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955468 1,108,025 - 1,117,366 (-) NCBI ChiLan1.0 ChiLan1.0
KCNK6 (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 20 44,604,902 - 44,623,635 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 19 46,475,224 - 46,495,898 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 19 35,409,752 - 35,422,490 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 19 43,984,592 - 43,995,374 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 19 43,985,074 - 43,995,374 (+) Ensembl panpan1.1 panPan2
KCNK6 (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 1 114,665,958 - 114,677,845 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 1 114,666,476 - 114,677,639 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 1 114,070,430 - 114,081,304 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 1 115,268,446 - 115,279,326 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 1 115,267,617 - 115,279,326 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 1 114,841,288 - 114,852,160 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 1 114,458,924 - 114,469,776 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 1 115,497,600 - 115,508,474 (-) NCBI UU_Cfam_GSD_1.0
Kcnk6 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024409349 12,927,338 - 12,937,848 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936801 1,092,692 - 1,103,210 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936801 1,092,694 - 1,101,940 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
KCNK6 (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 6 47,238,685 - 47,249,136 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 6 47,237,665 - 47,249,178 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 6 42,739,715 - 42,747,510 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
KCNK6 (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 6 32,959,275 - 32,977,601 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 6 32,962,535 - 32,973,196 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666073 10,904,586 - 10,921,256 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Kcnk6 (Heterocephalus glaber - naked mole-rat)
.
miRNA Target Status
Predicted Target Of
Count of predictions: 204 Count of miRNA genes: 150 Interacting mature miRNAs: 163 Transcripts: ENSRNOT00000027974, ENSRNOT00000032394 Prediction methods: Microtar, Miranda, Rnahybrid Result types: miRGate_prediction
QTLs in Region (mRatBN7.2)
2313059 Bss55 Bone structure and strength QTL 55 3.2 0.0001 tibia size trait (VT:0100001) tibia midshaft cross-sectional area (CMO:0001717) 1 43284731 118944897 Rat 631688 Hcas2 Hepatocarcinoma susceptibility QTL 2 3 0.0001 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 5925874 115540829 Rat 1578649 Bmd8 Bone mineral density QTL 8 4.9 femur mineral mass (VT:0010011) trabecular volumetric bone mineral density (CMO:0001729) 1 49393172 94393172 Rat 1582234 Gluco18 Glucose level QTL 18 3.4 0.0003 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 78479925 123479925 Rat 1358359 Sradr1 Stress Responsive Adrenal Weight QTL 1 4.74 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 1 30882023 123479925 Rat 634314 Niddm44 Non-insulin dependent diabetes mellitus QTL 44 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 49393289 199050459 Rat 1578780 Cm52 Cardiac mass QTL 52 3.3 0.0001 heart mass (VT:0007028) heart wet weight (CMO:0000069) 1 81591954 219808434 Rat 1578654 Bss10 Bone structure and strength QTL 10 4 femur morphology trait (VT:0000559) femoral neck cortical cross-sectional area (CMO:0001702) 1 49393172 159356837 Rat 1554320 Bmd1 Bone mineral density QTL 1 12.2 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 1 509108 86060548 Rat 2302059 Pia36 Pristane induced arthritis QTL 36 3.8 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 1 43333002 88333002 Rat 1300121 Hrtrt1 Heart rate QTL 1 3.7 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 1 65789093 115540829 Rat 7421628 Bp361 Blood pressure QTL 361 0.001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 1 66023617 118608521 Rat 631495 Bp96 Blood pressure QTL 96 4.52 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 22340647 102268831 Rat 70225 Bp58 Blood pressure QTL 58 3.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32356093 162846471 Rat 631512 Scl6 Serum cholesterol level QTL 6 9.6 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 1 72197680 90508767 Rat 2298545 Neuinf8 Neuroinflammation QTL 8 4.6 nervous system integrity trait (VT:0010566) spinal cord beta-2 microglobulin mRNA level (CMO:0002125) 1 57336763 151090257 Rat 2313072 Bss53 Bone structure and strength QTL 53 4.3 0.0001 tibia length (VT:0004357) tibia length (CMO:0000450) 1 43284731 118944897 Rat 10059597 Bp377 Blood pressure QTL 377 3.42 0.025 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 32737458 199368955 Rat 2313078 Bss54 Bone structure and strength QTL 54 3.5 0.0001 tibia area (VT:1000281) tibia midshaft cross-sectional area (CMO:0001717) 1 43284731 118944897 Rat 1549903 Bp267 Blood pressure QTL 267 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 77876254 106047988 Rat 2313083 Bmd74 Bone mineral density QTL 74 4 0.0001 tibia mineral mass (VT:1000283) total volumetric bone mineral density (CMO:0001728) 1 82174743 118944897 Rat 2313402 Anxrr24 Anxiety related response QTL 24 aggression-related behavior trait (VT:0015014) tameness/aggressiveness composite score (CMO:0002136) 1 48963584 144267916 Rat 4889494 Scort2 Serum corticosterone level QTL 2 4.2 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 1 80592172 125592172 Rat 61342 Bp27 Blood pressure QTL 27 3.4 0.0006 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 56732668 98773277 Rat 1300172 Bp172 Blood pressure QTL 172 3.56 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 1 32737273 90665040 Rat 61344 Bp29 Blood pressure QTL 29 7.5 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 1 78350581 123350581 Rat 1358192 Ept13 Estrogen-induced pituitary tumorigenesis QTL 13 3.4 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 1 77494165 122494165 Rat 2313094 Bss58 Bone structure and strength QTL 58 3.7 0.0001 tibia strength trait (VT:1000284) tibia total energy absorbed before break (CMO:0001736) 1 43284731 118944897 Rat 6903308 Scl36 Serum cholesterol QTL 36 2 0.0125 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 1 53863041 90532583 Rat 2300164 Bmd44 Bone mineral density QTL 44 5.4 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 1 56949932 101949932 Rat 2313099 Bss56 Bone structure and strength QTL 56 2.4 0.0001 tibia size trait (VT:0100001) tibia midshaft endosteal cross-sectional area (CMO:0001716) 1 43284731 118944897 Rat 2313098 Bmd70 Bone mineral density QTL 70 3.6 0.0001 tibia mineral mass (VT:1000283) compact volumetric bone mineral density (CMO:0001730) 1 43284731 118944897 Rat 738022 Anxrr13 Anxiety related response QTL 13 4.6 0.00039 locomotor behavior trait (VT:0001392) number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514) 1 83547917 128547917 Rat 152025249 Scl82 Serum cholesterol level QTL 82 4.77 blood cholesterol amount (VT:0000180) 1 50343510 99980958 Rat 10054135 Gmadr2 Adrenal mass QTL 2 1.97 0.0129 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 1 77857876 122857876 Rat 7411712 Strs4 Sensitivity to stroke QTL 4 8.7 cerebrum integrity trait (VT:0010549) percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932) 1 78430536 123430536 Rat 2313051 Bss57 Bone structure and strength QTL 57 3.7 0.0001 tibia strength trait (VT:1000284) bone polar moment of inertia (CMO:0001558) 1 43284731 118944897 Rat 61433 Cia2 Collagen induced arthritis QTL 2 5 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 1 78430754 91209302 Rat
Markers in Region
AI012809
Rat Assembly Chr Position (strand) Source JBrowse Rnor_5.0 1 153,151,053 - 153,151,545 NCBI Rnor5.0 Rnor_5.0 1 88,347,237 - 88,347,729 NCBI Rnor5.0 Rnor_5.0 1 89,344,028 - 89,344,520 NCBI Rnor5.0 RGSC_v3.4 1 84,359,903 - 84,360,394 UniSTS RGSC3.4 RGSC_v3.4 X 159,307,255 - 159,307,746 UniSTS RGSC3.4 Celera 1 78,913,051 - 78,913,542 UniSTS Celera 1 136,762,666 - 136,763,157 UniSTS RH 3.4 Map 1 885.0 UniSTS Cytogenetic Map 1 q21 UniSTS
Expression
RNA-SEQ Expression
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
12
12
55
63
55
31
12
31
12
104
48
31
13
37
24
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Sequence
Ensembl Acc Id:
ENSRNOT00000027974 ⟹ ENSRNOP00000027973
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 1 84,525,590 - 84,534,677 (-) Ensembl Rnor_6.0 Ensembl 1 87,166,109 - 87,174,821 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000032394 ⟹ ENSRNOP00000061815
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 1 88,169,378 - 88,176,610 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000089578 ⟹ ENSRNOP00000068630
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 1 87,167,395 - 87,174,530 (-) Ensembl
RefSeq Acc Id:
NM_053806 ⟹ NP_446258
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 93,653,247 - 93,661,419 (-) NCBI mRatBN7.2 1 84,525,775 - 84,533,948 (-) NCBI Rnor_6.0 1 88,168,438 - 88,176,610 (-) NCBI Rnor_5.0 1 89,343,864 - 89,352,036 (-) NCBI RGSC_v3.4 1 84,359,738 - 84,367,910 (-) RGD Celera 1 78,912,886 - 78,921,054 (-) RGD
Sequence:
ATGCGGCGGGGCGCGCTCCTGGCTAGCGCCCTGGTCGCCTACGCCGGGTACCTGGCGCTCGGCGCGCTGCTTGTGGCGCGGCTGGAGCGGCCGCACGAAGCCCGGCTGCGGGCAGAGCTGGGGACGCT GCGGGAGCAGCTGCTGCGGCACAGCCCGTGCGTGGCGGCTCACGCCCTGGACGCCTTCGTGGAGCGGGTGCTGGCGGCAGGACGGCTGGGGCGCGCAGTGCTGGCCAACGCATCGGGACCCGCCAACG CTTCGGACCCCGCGTGGGACTTTGCCTCGGCGCTCTTCTTCGCCAGCACGCTAGTCACCACCGTGGGCTATGGCTACACGACCCCACTGACGGATGCAGGCAAAGCCTTCTCCATCGTTTTTGCACTC CTGGGCGTGCCTATCACCATGCTACTTCTGACTGCCTCAGCCCAGCGCCTGTCACTGCTGCTCACCCACGCACCCCTGTCCTGGCTGAGCCTGCGCTGGGGCTGGCACCCGCAGCGGGCAGCCCGCTG GCACCTGGTGGCCCTACTGATGGTCATAGTGGCTATATTTTTCCTGATCCCGGCTGCGGTCTTCGCCTACCTTGAGGAGGCCTGGAGCTTTCTGGATGCTTTCTATTTCTGCTTCATCTCTCTGTCCA CCATTGGCCTGGGGGACTATGTGCCTGGGGAAGCCCCGGGCCAGCCTTACCGATCCCTCTACAAGGTGCTTGTCACAGCATACCTCTTCCTCGGCCTTGTTGCCATGGTGCTGGTGTTGCAGACTTTC CGCCGTGTTTCTGACCTCCATGGCCTCACTGAACTCATCTTGCTGCCGGATCCCGACCCTGCCAGGCTCCACCAGGATGAGGATGACCAGGTGGACATTCTGGATGCCCGGACAGATCTGCATCAGCA TCTCTCTGCTGCCTCCCACGCTAATTACGCCTCCATCCCCAGGTAGCTGTCGACCTGGACACACCTGGCCTGGGCTTTGGGCCCCATGTGATTAGATCAACTAGAAAGCCCACTCACACTCTCCACTG GGAGGTGAGGAGTAGCCGCTTTGCTCCTGTGTCCTCCGCTCCTCAGGGCCCTGACACAGTCATTTTCTCCTCCTATCTTTTCTCCCATTTCTTCTCAGACTCTGACCGTTTGGGCTTTCTGACTTTGT GAGAGTGGTGGTTTCTATGCCTTTTTGTTTTGTTTTGTTCTTGTTCTTCTGTATCTCACTCTCTTGCATAGTACATCTGGCACATCCAGTTCTTCTGGGCTCCAACCCTGGGCTCCATTTCAGCCAGT GAGGTAAACTGACCGACTGGTCCCTTGACAGTGACAAGCTCCAGTGGGCACCAGAAGAGGCAAGAGTAGCCAGGACTGAGGAGTGAACCTGATATGTTCAGGGTTATCTTTCCTGGGGACAGGAACTA ACCCAAGACCTGCTAGTCAAGAGAAAAAATAGTCCCTTCTCCTCAGGTGTCTATGGGCCATAGTACCTGTGGGAAGAGGCCTGCAATGGGCCAGCATCTCCCTCAGTGACTTAACAGGCAAGGAACTG ACCCAGGATATGAGCCGAGATCCAAGTGGCATGAGACAAGCAGCTTAGCGTAGTTCCTGTGGTGATACCATGTCTTTTACTGGGCATTGATGGCCGTGGGCTCTGGAGCCAGTCTTCCTGGGCGTGCC CTGTGACTGGGCCATGTTTCACCAATGCATTTGGACGGTCACTCTACCTTTCAGACTCTGTCTCCTAAATGGTGACCATAATAACGCTTACTCTAAAAGGCGAACTCAACCAGTAGCACATGCCTGTA ACCTGAGCTGAAGCAGGAGGCTTGAGAGTTCAAAGGCAGGAGCCAGGCAATAAAACAATGTAAGCAATAAAATAATAATAATGATGATGAAAAAAAAAAAAAAAAA
hide sequence
RefSeq Acc Id:
XM_039109439 ⟹ XP_038965367
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 93,652,888 - 93,661,237 (-) NCBI mRatBN7.2 1 84,525,613 - 84,533,762 (-) NCBI
RefSeq Acc Id:
XM_039109467 ⟹ XP_038965395
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 93,652,888 - 93,661,238 (-) NCBI mRatBN7.2 1 84,525,613 - 84,533,768 (-) NCBI
RefSeq Acc Id:
XM_039109523 ⟹ XP_038965451
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 1 93,652,888 - 93,661,222 (-) NCBI mRatBN7.2 1 84,525,613 - 84,533,760 (-) NCBI
RefSeq Acc Id:
NP_446258 ⟸ NM_053806
- UniProtKB:
Q9ERU4 (UniProtKB/Swiss-Prot), G3V8R8 (UniProtKB/TrEMBL), Q9ERU5 (UniProtKB/TrEMBL), A6J9P6 (UniProtKB/TrEMBL)
- Sequence:
MRRGALLASALVAYAGYLALGALLVARLERPHEARLRAELGTLREQLLRHSPCVAAHALDAFVERVLAAGRLGRAVLANASGPANASDPAWDFASALFFASTLVTTVGYGYTTPLTDAGKAFSIVFAL LGVPITMLLLTASAQRLSLLLTHAPLSWLSLRWGWHPQRAARWHLVALLMVIVAIFFLIPAAVFAYLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRSLYKVLVTAYLFLGLVAMVLVLQTF RRVSDLHGLTELILLPDPDPARLHQDEDDQVDILDARTDLHQHLSAASHANYASIPR
hide sequence
Ensembl Acc Id:
ENSRNOP00000061815 ⟸ ENSRNOT00000032394
RefSeq Acc Id:
XP_038965395 ⟸ XM_039109467
- Peptide Label:
isoform X1
RefSeq Acc Id:
XP_038965367 ⟸ XM_039109439
- Peptide Label:
isoform X1
RefSeq Acc Id:
XP_038965451 ⟸ XM_039109523
- Peptide Label:
isoform X1
Ensembl Acc Id:
ENSRNOP00000068630 ⟸ ENSRNOT00000089578
Ensembl Acc Id:
ENSRNOP00000027973 ⟸ ENSRNOT00000027974
Promoters
RGD ID: 13689901
Promoter ID: EPDNEW_R426
Type: initiation region
Name: Kcnk6_1
Description: potassium two pore domain channel subfamily K member 6
SO ACC ID: SO:0000170
Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ )
Experiment Methods: Single-end sequencing.
Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 1 88,176,613 - 88,176,673 EPDNEW
Additional Information
External Database Links
Database
Acc Id
Source(s)
AGR Gene
RGD:621450
AgrOrtholog
BioCyc Gene
G2FUF-60187
BioCyc
Ensembl Genes
ENSRNOG00000020598
Ensembl, UniProtKB/Swiss-Prot
ENSRNOG00000049868
Ensembl
ENSRNOG00055033381
UniProtKB/Swiss-Prot
ENSRNOG00060032841
UniProtKB/Swiss-Prot
ENSRNOG00065034067
UniProtKB/Swiss-Prot
Ensembl Transcript
ENSRNOT00000027974.6
UniProtKB/Swiss-Prot
ENSRNOT00055057721
UniProtKB/Swiss-Prot
ENSRNOT00060056907
UniProtKB/Swiss-Prot
ENSRNOT00065058534
UniProtKB/Swiss-Prot
Gene3D-CATH
1.10.287.70
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro
2pore_dom_K_chnl
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
2pore_dom_K_chnl_TASK
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
2pore_dom_K_chnl_TWIK
UniProtKB/Swiss-Prot
2pore_dom_K_chnl_TWIK2
UniProtKB/Swiss-Prot
Ion_trans_2
UniProtKB/TrEMBL
K_chnl_2pore_TWIK
UniProtKB/TrEMBL
K_chnl_2pore_TWIK2
UniProtKB/TrEMBL
K_chnl_dom
UniProtKB/Swiss-Prot
KEGG Report
rno:116491
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene
116491
ENTREZGENE
PANTHER
POTASSIUM CHANNEL SUBFAMILY K MEMBER 6
UniProtKB/Swiss-Prot
POTASSIUM CHANNEL, SUBFAMILY K
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PTHR11003:SF28
UniProtKB/TrEMBL
Pfam
Ion_trans_2
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen
Kcnk6
PhenoGen
PIRSF
K_channel_subfamily_K_type
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS
2POREKCHANEL
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TWIK2CHANNEL
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TWIKCHANNEL
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx
ENSRNOG00000020598
RatGTEx
ENSRNOG00000049868
RatGTEx
ENSRNOG00055033381
RatGTEx
ENSRNOG00060032841
RatGTEx
ENSRNOG00065034067
RatGTEx
Superfamily-SCOP
Voltage-gated potassium channels
UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt
A6J9P6
ENTREZGENE, UniProtKB/TrEMBL
G3V8R8
ENTREZGENE, UniProtKB/Swiss-Prot
Q9ERU4
ENTREZGENE
Q9ERU5
ENTREZGENE
UniProt Secondary
Q9ERU4
UniProtKB/Swiss-Prot
Q9ERU5
UniProtKB/Swiss-Prot
Nomenclature History
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2021-03-09
Kcnk6
potassium two pore domain channel subfamily K member 6
LOC100909725
potassium channel subfamily K member 6-like
Data merged from RGD:6501929
737654
PROVISIONAL
2016-02-11
Kcnk6
potassium two pore domain channel subfamily K member 6
Kcnk6
potassium channel, two pore domain subfamily K, member 6
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2015-01-26
Kcnk6
potassium channel, two pore domain subfamily K, member 6
Kcnk6
potassium channel, subfamily K, member 6
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2012-07-05
LOC100909725
potassium channel subfamily K member 6-like
Symbol and Name status set to provisional
70820
PROVISIONAL
2010-04-20
Kcnk6
potassium channel, subfamily K, member 6
Kcnk6
potassium inwardly-rectifying channel, subfamily K, member 6
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2008-02-22
Kcnk6
potassium inwardly-rectifying channel, subfamily K, member 6
Kcnk6
potassium channel, subfamily K, member 6
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2005-01-20
Kcnk6
potassium channel, subfamily K, member 6
potassium channel, subfamily K, member 6 (TWIK-2)
Name updated
1299863
APPROVED
2002-08-07
Kcnk6
potassium channel, subfamily K, member 6 (TWIK-2)
Symbol and Name status set to provisional
70820
PROVISIONAL
RGD Curation Notes
Note Type
Note
Reference
gene_domains
contains 2P domains
633163
gene_other
shows an extremely low conductance
633163