Myo9a (myosin IXA) - Rat Genome Database

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Gene: Myo9a (myosin IXA) Rattus norvegicus
Analyze
Symbol: Myo9a
Name: myosin IXA
RGD ID: 621395
Description: Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in several processes, including establishment of epithelial cell apical/basal polarity; postsynaptic specialization organization; and regulation of neuron projection arborization. Is active in glutamatergic synapse and postsynapse. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome. Orthologous to human MYO9A (myosin IXA); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: myosin-IXa; myr 7; unconventional myosin-9a; unconventional myosin-IXa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Myo9aTn(sb-T2/Bart3)2.186Mcwi  
Genetic Models: F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi
Candidate Gene For: Vetf5
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8869,044,853 - 69,248,094 (+)NCBIGRCr8
mRatBN7.2860,149,234 - 60,352,330 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl860,149,234 - 60,350,514 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx865,671,483 - 65,874,440 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0863,944,409 - 64,147,367 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0861,813,862 - 62,016,821 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0864,573,248 - 64,777,607 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl864,573,358 - 64,777,543 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0864,335,907 - 64,534,890 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4863,578,001 - 63,783,813 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1863,597,054 - 63,802,860 (+)NCBI
Celera859,592,114 - 59,790,799 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Myosin IXa Binds AMPAR and Regulates Synaptic Structure, LTP, and Cognitive Function. Folci A, etal., Front Mol Neurosci. 2016 Jan 20;9:1. doi: 10.3389/fnmol.2016.00001. eCollection 2016.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:22891260   PMID:27259756  


Genomics

Comparative Map Data
Myo9a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8869,044,853 - 69,248,094 (+)NCBIGRCr8
mRatBN7.2860,149,234 - 60,352,330 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl860,149,234 - 60,350,514 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx865,671,483 - 65,874,440 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0863,944,409 - 64,147,367 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0861,813,862 - 62,016,821 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0864,573,248 - 64,777,607 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl864,573,358 - 64,777,543 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0864,335,907 - 64,534,890 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4863,578,001 - 63,783,813 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1863,597,054 - 63,802,860 (+)NCBI
Celera859,592,114 - 59,790,799 (+)NCBICelera
Cytogenetic Map8q24NCBI
MYO9A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381571,822,291 - 72,118,600 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1571,822,291 - 72,118,577 (-)EnsemblGRCh38hg38GRCh38
GRCh371572,114,632 - 72,410,491 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361569,905,405 - 70,197,476 (-)NCBINCBI36Build 36hg18NCBI36
Build 341569,905,416 - 70,197,245NCBI
Celera1549,004,720 - 49,296,754 (-)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1548,948,830 - 49,240,766 (-)NCBIHuRef
CHM1_11572,236,489 - 72,528,413 (-)NCBICHM1_1
T2T-CHM13v2.01569,641,241 - 69,935,336 (-)NCBIT2T-CHM13v2.0
Myo9a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39959,658,128 - 59,836,149 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl959,658,179 - 59,836,149 (+)EnsemblGRCm39 Ensembl
GRCm38959,750,848 - 59,928,866 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl959,750,896 - 59,928,866 (+)EnsemblGRCm38mm10GRCm38
MGSCv37959,598,981 - 59,776,673 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36959,549,191 - 59,726,872 (+)NCBIMGSCv36mm8
Celera956,978,493 - 57,156,228 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.13NCBI
Myo9a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554505,049,864 - 5,252,721 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554505,049,797 - 5,256,934 (+)NCBIChiLan1.0ChiLan1.0
MYO9A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21661,085,423 - 61,383,454 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11565,249,695 - 65,547,657 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01550,771,747 - 51,069,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11569,537,071 - 69,833,597 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1569,541,318 - 69,760,771 (-)Ensemblpanpan1.1panPan2
MYO9A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13035,386,299 - 35,606,993 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3035,389,424 - 35,606,859 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3035,322,734 - 35,586,056 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03035,592,114 - 35,853,053 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3035,592,118 - 35,852,421 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13035,542,999 - 35,806,184 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03035,570,983 - 35,834,592 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03035,825,200 - 36,087,946 (-)NCBIUU_Cfam_GSD_1.0
Myo9a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640113,407,324 - 113,700,707 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647131,259,652 - 31,473,926 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647131,255,387 - 31,548,819 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYO9A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1169,374,311 - 169,596,412 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11169,370,028 - 169,596,771 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21188,117,293 - 188,197,196 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYO9A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12611,339,033 - 11,640,982 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2611,339,246 - 11,639,956 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048129,926,660 - 130,235,887 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myo9a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247811,967,671 - 2,175,150 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247811,900,669 - 2,179,269 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myo9a
513 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:154
Count of miRNA genes:129
Interacting mature miRNAs:140
Transcripts:ENSRNOT00000015963
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83084815461290444Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815461290444Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)81629044461290444Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat

Markers in Region
STS-F03912  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2860,315,682 - 60,315,785 (+)MAPPERmRatBN7.2
Rnor_6.0864,743,310 - 64,743,412NCBIRnor6.0
Rnor_5.0864,503,072 - 64,503,174UniSTSRnor5.0
RGSC_v3.4863,780,939 - 63,781,041UniSTSRGSC3.4
Celera859,758,103 - 59,758,205UniSTS
Cytogenetic Map8q24UniSTS
RH143491  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2860,219,959 - 60,220,201 (+)MAPPERmRatBN7.2
Rnor_6.0864,643,166 - 64,643,407NCBIRnor6.0
Rnor_5.0864,405,402 - 64,405,643UniSTSRnor5.0
RGSC_v3.4863,648,517 - 63,648,758UniSTSRGSC3.4
Celera859,662,759 - 59,663,004UniSTS
RH 3.4 Map8701.89UniSTS
Cytogenetic Map8q24UniSTS
MYO9A_8489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2860,348,323 - 60,349,101 (+)MAPPERmRatBN7.2
Rnor_6.0864,777,203 - 64,777,980NCBIRnor6.0
Rnor_5.0864,534,488 - 64,535,265UniSTSRnor5.0
Celera859,790,397 - 59,791,174UniSTS
Cytogenetic Map8q24UniSTS


Genetic Models
This gene Myo9a is modified in the following models/strains:
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000015963   ⟹   ENSRNOP00000015963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl860,149,234 - 60,350,514 (+)Ensembl
Rnor_6.0 Ensembl864,610,952 - 64,777,345 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000083558   ⟹   ENSRNOP00000070271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl860,149,234 - 60,350,514 (+)Ensembl
Rnor_6.0 Ensembl864,573,358 - 64,777,543 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103923   ⟹   ENSRNOP00000078500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl860,149,234 - 60,350,514 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104304   ⟹   ENSRNOP00000093434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl860,149,234 - 60,350,514 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118561   ⟹   ENSRNOP00000086148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl860,149,234 - 60,350,514 (+)Ensembl
RefSeq Acc Id: NM_134335   ⟹   NP_599162
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,045,014 - 69,248,094 (+)NCBI
mRatBN7.2860,149,234 - 60,352,330 (+)NCBI
Rnor_6.0864,573,248 - 64,777,607 (+)NCBI
Rnor_5.0864,335,907 - 64,534,890 (+)NCBI
RGSC_v3.4863,578,001 - 63,783,813 (+)RGD
Celera859,592,114 - 59,790,799 (+)RGD
Sequence:
RefSeq Acc Id: XM_063264814   ⟹   XP_063120884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264815   ⟹   XP_063120885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264816   ⟹   XP_063120886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264817   ⟹   XP_063120887
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264818   ⟹   XP_063120888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,853 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264819   ⟹   XP_063120889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264820   ⟹   XP_063120890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264821   ⟹   XP_063120891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,248,094 (+)NCBI
RefSeq Acc Id: XM_063264822   ⟹   XP_063120892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,111,860 - 69,248,094 (+)NCBI
RefSeq Acc Id: XR_010053925
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,202,512 (+)NCBI
RefSeq Acc Id: XR_010053926
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8869,044,864 - 69,202,512 (+)NCBI
RefSeq Acc Id: NP_599162   ⟸   NM_134335
- UniProtKB: Q9Z1N3 (UniProtKB/Swiss-Prot),   F1LMQ1 (UniProtKB/TrEMBL),   A6J540 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070271   ⟸   ENSRNOT00000083558
Ensembl Acc Id: ENSRNOP00000015963   ⟸   ENSRNOT00000015963
Ensembl Acc Id: ENSRNOP00000078500   ⟸   ENSRNOT00000103923
Ensembl Acc Id: ENSRNOP00000093434   ⟸   ENSRNOT00000104304
Ensembl Acc Id: ENSRNOP00000086148   ⟸   ENSRNOT00000118561
RefSeq Acc Id: XP_063120888   ⟸   XM_063264818
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063120884   ⟸   XM_063264814
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120885   ⟸   XM_063264815
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JXH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120886   ⟸   XM_063264816
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063120890   ⟸   XM_063264820
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A5W4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120891   ⟸   XM_063264821
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063120889   ⟸   XM_063264819
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063120887   ⟸   XM_063264817
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063120892   ⟸   XM_063264822
- Peptide Label: isoform X9
Protein Domains
IQ   Myosin motor   Phorbol-ester/DAG-type   Ras-associating   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1N3-F1-model_v2 AlphaFold Q9Z1N3 1-2626 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696049
Promoter ID:EPDNEW_R6568
Type:single initiation site
Name:Myo9a_1
Description:myosin IXA
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0864,573,432 - 64,573,492EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621395 AgrOrtholog
BioCyc Gene G2FUF-30229 BioCyc
Ensembl Genes ENSRNOG00000011619 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015963.7 UniProtKB/TrEMBL
  ENSRNOT00000083558.2 UniProtKB/TrEMBL
  ENSRNOT00000103923.1 UniProtKB/TrEMBL
  ENSRNOT00000104304.1 UniProtKB/TrEMBL
  ENSRNOT00000118561.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.20.240.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IQ_motif_EF-hand-BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myo9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYO9A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYSc_Myo9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171296 UniProtKB/Swiss-Prot
NCBI Gene 171296 ENTREZGENE
PANTHER PTHR46184:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myosin_head UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00612 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00788 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myo9a PhenoGen
PRINTS MYOSINHEAVY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011619 RatGTEx
SMART MYSc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00314 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57889 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JXH4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A5W4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AIZ2_RAT UniProtKB/TrEMBL
  A0A8I6G310_RAT UniProtKB/TrEMBL
  A6J540 ENTREZGENE, UniProtKB/TrEMBL
  A6J541_RAT UniProtKB/TrEMBL
  F1LMQ1 ENTREZGENE, UniProtKB/TrEMBL
  MYO9A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Myo9a  myosin IXA      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Myo9a  myosin IXA      Symbol and Name status set to provisional 70820 PROVISIONAL