Lin7c (lin-7 cell polarity scaffold C) - Rat Genome Database

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Gene: Lin7c (lin-7 cell polarity scaffold C) Rattus norvegicus
Analyze
Symbol: Lin7c
Name: lin-7 cell polarity scaffold C (Ensembl:lin-7 homolog C, crumbs cell polarity complex component)
RGD ID: 621164
Description: Enables PDZ domain binding activity. Predicted to be involved in several processes, including morphogenesis of an epithelial sheet; regulation of synaptic assembly at neuromuscular junction; and synaptic vesicle transport. Located in cell-cell junction. Is active in glutamatergic synapse. Orthologous to human LIN7C (lin-7 homolog C, crumbs cell polarity complex component); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lin 7 homolog C; lin 7 homolog C (C. elegans); lin-7 homolog C; lin-7 homolog C (C. elegans); lin-7 homolog C, crumbs cell polarity complex component; lin-7-C; lin-7C; MALS-3; mammalian lin-seven protein 3; veli-3 protein; Veli3; vertebrate lin-7 homolog 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83116,859,425 - 116,872,363 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3116,860,282 - 116,872,363 (+)EnsemblGRCr8
mRatBN7.2396,406,800 - 96,417,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl396,406,813 - 96,417,728 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx399,967,159 - 99,974,467 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03108,566,119 - 108,573,427 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03106,329,474 - 106,336,786 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03101,010,923 - 101,018,235 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3101,010,899 - 101,018,433 (+)Ensemblrn6Rnor6.0
Rnor_5.03107,611,032 - 107,618,344 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4395,327,942 - 95,335,254 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera395,431,335 - 95,438,647 (+)NCBICelera
RGSC_v3.1395,224,369 - 95,231,682 (+)NCBI
Cytogenetic Map3q34NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. CASK associates with glutamate receptor interacting protein and signaling molecules. Hong CJ and Hsueh YP, Biochem Biophys Res Commun. 2006 Dec 22;351(3):771-6. Epub 2006 Oct 30.
3. Isolation and characterization of mammalian homologues of Caenorhabditis elegans lin-7: localization at cell-cell junctions. Irie M, etal., Oncogene 1999 May 6;18(18):2811-7.
4. A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels. Leonoudakis D, etal., J Biol Chem 2004 Apr 30;279(18):19051-63. Epub 2004 Feb 11.
5. Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. Leonoudakis D, etal., J Biol Chem. 2004 May 21;279(21):22331-46. Epub 2004 Mar 15.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16186258   PMID:17237226   PMID:17604280   PMID:17987659   PMID:18403412   PMID:20702775   PMID:23201090   PMID:23376485   PMID:35352799  


Genomics

Comparative Map Data
Lin7c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83116,859,425 - 116,872,363 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3116,860,282 - 116,872,363 (+)EnsemblGRCr8
mRatBN7.2396,406,800 - 96,417,779 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl396,406,813 - 96,417,728 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx399,967,159 - 99,974,467 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03108,566,119 - 108,573,427 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03106,329,474 - 106,336,786 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03101,010,923 - 101,018,235 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3101,010,899 - 101,018,433 (+)Ensemblrn6Rnor6.0
Rnor_5.03107,611,032 - 107,618,344 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4395,327,942 - 95,335,254 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera395,431,335 - 95,438,647 (+)NCBICelera
RGSC_v3.1395,224,369 - 95,231,682 (+)NCBI
Cytogenetic Map3q34NCBI
LIN7C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381127,494,418 - 27,506,769 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1127,494,418 - 27,506,769 (-)Ensemblhg38GRCh38
GRCh371127,515,965 - 27,528,316 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,472,699 - 27,484,879 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341127,472,699 - 27,484,879NCBI
Celera1127,661,655 - 27,674,034 (-)NCBICelera
Cytogenetic Map11p14.1NCBI
HuRef1127,214,688 - 27,227,063 (-)NCBIHuRef
CHM1_11127,515,302 - 27,527,664 (-)NCBICHM1_1
T2T-CHM13v2.01127,634,869 - 27,647,239 (-)NCBIT2T-CHM13v2.0
Lin7c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392109,721,205 - 109,731,348 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2109,721,198 - 109,731,348 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382109,890,878 - 109,900,937 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2109,890,853 - 109,901,003 (+)Ensemblmm10GRCm38
MGSCv372109,731,035 - 109,741,094 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362109,691,717 - 109,701,776 (+)NCBIMGSCv36mm8
Celera2111,051,913 - 111,061,966 (+)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.65NCBI
Lin7c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554766,650,106 - 6,658,817 (-)Ensembl
ChiLan1.0NW_0049554766,650,539 - 6,658,811 (-)NCBIChiLan1.0ChiLan1.0
LIN7C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2929,705,210 - 29,717,388 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11129,705,738 - 29,717,917 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,458,735 - 27,471,068 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11127,361,291 - 27,373,440 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1127,361,301 - 27,373,440 (-)EnsemblpanPan2panpan1.1
Lin7c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494736,572,620 - 36,582,951 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365405,727,435 - 5,737,924 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365405,727,463 - 5,736,696 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIN7C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl232,845,208 - 32,856,322 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1232,844,928 - 32,855,166 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2235,428,346 - 35,438,699 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIN7C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1137,598,442 - 37,610,568 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl137,598,475 - 37,606,392 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038134,908,426 - 134,920,431 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lin7c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476617,161,179 - 17,167,073 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476617,159,205 - 17,167,119 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Lin7c
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1588,185,026 - 88,195,889 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Lin7c
157 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:366
Count of miRNA genes:206
Interacting mature miRNAs:268
Transcripts:ENSRNOT00000073258
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)381541464126563126Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1582252Sual1Serum uric acid level QTL 13.40.0123blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)3116582412122654872Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
D3Rat290  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,411,234 - 96,411,356 (+)MAPPERmRatBN7.2
Rnor_6.03101,015,333 - 101,015,454NCBIRnor6.0
Rnor_5.03107,615,442 - 107,615,563UniSTSRnor5.0
RGSC_v3.4395,332,351 - 95,332,473RGDRGSC3.4
RGSC_v3.4395,332,352 - 95,332,473UniSTSRGSC3.4
Celera395,435,745 - 95,435,866UniSTS
RGSC_v3.1395,228,779 - 95,228,901RGD
FHH x ACI Map355.57RGD
FHH x ACI Map355.57UniSTS
Cytogenetic Map3q33UniSTS
BE106900  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2396,416,119 - 96,416,317 (+)MAPPERmRatBN7.2
Rnor_6.03101,020,218 - 101,020,415NCBIRnor6.0
Rnor_5.03107,620,327 - 107,620,524UniSTSRnor5.0
RGSC_v3.4395,337,237 - 95,337,434UniSTSRGSC3.4
Celera395,440,630 - 95,440,827UniSTS
RH 3.4 Map3757.1UniSTS
Cytogenetic Map3q33UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000073258   ⟹   ENSRNOP00000065941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3101,010,899 - 101,018,433 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103172   ⟹   ENSRNOP00000093334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3116,861,463 - 116,872,363 (+)Ensembl
mRatBN7.2 Ensembl396,406,813 - 96,417,728 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107137   ⟹   ENSRNOP00000077925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3116,864,709 - 116,872,363 (+)Ensembl
mRatBN7.2 Ensembl396,410,125 - 96,417,728 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111185   ⟹   ENSRNOP00000095729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl396,409,946 - 96,417,728 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000156464   ⟹   ENSRNOP00000106167
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3116,860,282 - 116,869,037 (+)Ensembl
RefSeq Acc Id: NM_021851   ⟹   NP_068623
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,861,384 - 116,872,363 (+)NCBI
mRatBN7.2396,406,800 - 96,417,779 (+)NCBI
Rnor_6.03101,010,923 - 101,018,235 (+)NCBI
Rnor_5.03107,611,032 - 107,618,344 (+)NCBI
RGSC_v3.4395,327,942 - 95,335,254 (+)RGD
Celera395,431,335 - 95,438,647 (+)RGD
Sequence:
RefSeq Acc Id: XM_063284463   ⟹   XP_063140533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,860,297 - 116,872,363 (+)NCBI
RefSeq Acc Id: XM_063284464   ⟹   XP_063140534
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83116,859,425 - 116,872,363 (+)NCBI
Protein Sequences
Protein RefSeqs NP_068623 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140533 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140534 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC78075 (Get FASTA)   NCBI Sequence Viewer  
  EDL79758 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000093334
  ENSRNOP00000093334.1
  ENSRNOP00000106167
GenBank Protein Q792I0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_068623   ⟸   NM_021851
- UniProtKB: Q792I0 (UniProtKB/Swiss-Prot),   A6HP07 (UniProtKB/TrEMBL),   A0A8I5Y1R3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065941   ⟸   ENSRNOT00000073258
Ensembl Acc Id: ENSRNOP00000095729   ⟸   ENSRNOT00000111185
Ensembl Acc Id: ENSRNOP00000077925   ⟸   ENSRNOT00000107137
Ensembl Acc Id: ENSRNOP00000093334   ⟸   ENSRNOT00000103172
RefSeq Acc Id: XP_063140534   ⟸   XM_063284464
- Peptide Label: isoform X1
- UniProtKB: Q792I0 (UniProtKB/Swiss-Prot),   A0A8I5Y1R3 (UniProtKB/TrEMBL),   A6HP07 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140533   ⟸   XM_063284463
- Peptide Label: isoform X1
- UniProtKB: Q792I0 (UniProtKB/Swiss-Prot),   A0A8I5Y1R3 (UniProtKB/TrEMBL),   A6HP07 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106167   ⟸   ENSRNOT00000156464
Protein Domains
L27   PDZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q792I0-F1-model_v2 AlphaFold Q792I0 1-197 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692280
Promoter ID:EPDNEW_R2805
Type:multiple initiation site
Name:Lin7c_1
Description:lin-7 homolog C, crumbs cell polarity complex component
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03101,010,898 - 101,010,958EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621164 AgrOrtholog
BioCyc Gene G2FUF-48478 BioCyc
Ensembl Genes ENSRNOG00000045698 Ensembl
  ENSRNOG00000062543 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000103172 ENTREZGENE
  ENSRNOT00000103172.1 UniProtKB/Swiss-Prot
  ENSRNOT00000156464 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot
  L27 domain UniProtKB/Swiss-Prot
InterPro L27_C UniProtKB/Swiss-Prot
  L27_dom UniProtKB/Swiss-Prot
  L27_dom_sf UniProtKB/Swiss-Prot
  LIN7 UniProtKB/Swiss-Prot
  MAM_complex_regulator UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:60442 UniProtKB/Swiss-Prot
NCBI Gene 60442 ENTREZGENE
PANTHER PROTEIN LIN-7 HOMOLOG UniProtKB/Swiss-Prot
Pfam L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
PhenoGen Lin7c PhenoGen
PIRSF Lin-7_homologue UniProtKB/Swiss-Prot
PROSITE L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000045698 RatGTEx
  ENSRNOG00000062543 RatGTEx
SMART L27 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF101288 UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
UniProt A0A8I5Y1R3 ENTREZGENE, UniProtKB/TrEMBL
  A6HP07 ENTREZGENE, UniProtKB/TrEMBL
  LIN7C_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Lin7c  lin-7 cell polarity scaffold C  Lin7c  lin-7 homolog C, crumbs cell polarity complex component  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-01 Lin7c  lin-7 homolog C, crumbs cell polarity complex component  Lin7c  lin-7 homolog C (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Lin7c  lin-7 homolog C (C. elegans)    lin-7-C  Name updated 1299863 APPROVED
2002-08-07 Lin7c  lin-7-C      Symbol and Name status set to provisional 70820 PROVISIONAL