Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lin7c | Rat | (S)-nicotine | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | Nicotine results in decreased expression of LIN7C mRNA | CTD | PMID:21955143 | Lin7c | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LIN7C mRNA | CTD | PMID:22206623 | Lin7c | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of LIN7C mRNA | CTD | PMID:29097150 | Lin7c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LIN7C mRNA | CTD | PMID:32109520 | Lin7c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LIN7C mRNA | CTD | PMID:33387578 | Lin7c | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of LIN7C mRNA | CTD | PMID:21346803 | Lin7c | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LIN7C mRNA | CTD | PMID:30851411 | Lin7c | Rat | acrylamide | affects expression | EXP | | 6480464 | Acrylamide affects the expression of LIN7C mRNA | CTD | PMID:28959563 | Lin7c | Rat | aflatoxin B1 | increases expression | ISO | Lin7c (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of LIN7C mRNA | CTD | PMID:19770486 | Lin7c | Rat | aflatoxin M1 | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of LIN7C mRNA | CTD | PMID:30928695 | Lin7c | Rat | all-trans-retinoic acid | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of LIN7C mRNA | CTD | PMID:33167477 | Lin7c | Rat | Aroclor 1254 | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of LIN7C mRNA | CTD | PMID:23650126 | Lin7c | Rat | arsenous acid | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of LIN7C mRNA | CTD | PMID:20458559 | Lin7c | Rat | benzo[a]pyrene | increases expression | ISO | Lin7c (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of LIN7C mRNA | CTD | PMID:22228805 | Lin7c | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of LIN7C mRNA | CTD | PMID:25181051 | Lin7c | Rat | bisphenol A | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | bisphenol A results in decreased expression of LIN7C mRNA | CTD | PMID:33221593 | Lin7c | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LIN7C mRNA | CTD | PMID:29097150 | Lin7c | Rat | chlorpyrifos | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of LIN7C mRNA | CTD | PMID:37019170 | Lin7c | Rat | cisplatin | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of LIN7C mRNA | CTD | PMID:27594783 | Lin7c | Rat | cocaine | increases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Cocaine results in increased expression of LIN7C mRNA | CTD | PMID:18000554 | Lin7c | Rat | coumestrol | increases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Coumestrol results in increased expression of LIN7C mRNA | CTD | PMID:19167446 | Lin7c | Rat | diarsenic trioxide | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of LIN7C mRNA | CTD | PMID:20458559 | Lin7c | Rat | Dibutyl phosphate | affects expression | ISO | LIN7C (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of LIN7C mRNA | CTD | PMID:37042841 | Lin7c | Rat | dioxygen | increases expression | ISO | Lin7c (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of LIN7C mRNA | CTD | PMID:24205000 | Lin7c | Rat | doxorubicin | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of LIN7C mRNA | CTD | PMID:29803840 | Lin7c | Rat | enzyme inhibitor | multiple interactions | ISO | LIN7C (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of LIN7C protein | CTD | PMID:23301498 | Lin7c | Rat | ethanol | increases expression | ISO | Lin7c (Mus musculus) | 6480464 | Ethanol results in increased expression of LIN7C mRNA | CTD | PMID:21955143 | Lin7c | Rat | ethanol | affects expression | ISO | Lin7c (Mus musculus) | 6480464 | Ethanol affects the expression of LIN7C mRNA | CTD | PMID:30319688 | Lin7c | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of LIN7C mRNA | CTD | PMID:33387578 | Lin7c | Rat | hydrogen peroxide | affects expression | ISO | LIN7C (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of LIN7C mRNA | CTD | PMID:20044591 | Lin7c | Rat | ivermectin | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LIN7C protein | CTD | PMID:32959892 | Lin7c | Rat | methylparaben | increases expression | ISO | LIN7C (Homo sapiens) | 6480464 | methylparaben results in increased expression of LIN7C mRNA | CTD | PMID:38568856 | Lin7c | Rat | miconazole | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | Miconazole results in decreased expression of LIN7C mRNA | CTD | PMID:27462272 | Lin7c | Rat | morphine | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | Morphine results in decreased expression of LIN7C mRNA | CTD | PMID:21955143 | Lin7c | Rat | nickel dichloride | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | nickel chloride results in decreased expression of LIN7C mRNA | CTD | PMID:17312168 | Lin7c | Rat | nicotine | decreases expression | ISO | Lin7c (Mus musculus) | 6480464 | Nicotine results in decreased expression of LIN7C mRNA | CTD | PMID:21955143 | Lin7c | Rat | paracetamol | affects expression | ISO | Lin7c (Mus musculus) | 6480464 | Acetaminophen affects the expression of LIN7C mRNA | CTD | PMID:17562736 | Lin7c | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of LIN7C mRNA | CTD | PMID:27153767 | Lin7c | Rat | phenobarbital | affects expression | ISO | Lin7c (Mus musculus) | 6480464 | Phenobarbital affects the expression of LIN7C mRNA | CTD | PMID:19136022 | Lin7c | Rat | pirinixic acid | affects expression | ISO | Lin7c (Mus musculus) | 6480464 | pirinixic acid affects the expression of LIN7C mRNA | CTD | PMID:19136022 | Lin7c | Rat | pirinixic acid | increases expression | ISO | Lin7c (Mus musculus) | 6480464 | pirinixic acid results in increased expression of LIN7C mRNA | CTD | PMID:17426115 | Lin7c | Rat | rac-lactic acid | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of LIN7C mRNA | CTD | PMID:30851411 | Lin7c | Rat | resveratrol | multiple interactions | ISO | LIN7C (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of LIN7C mRNA | CTD | PMID:23557933 | Lin7c | Rat | sarin | increases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Sarin results in increased expression of LIN7C mRNA | CTD | PMID:19522546 | Lin7c | Rat | sodium arsenate | increases expression | ISO | Lin7c (Mus musculus) | 6480464 | sodium arsenate results in increased expression of LIN7C mRNA | CTD | PMID:21795629 | Lin7c | Rat | sodium arsenite | affects methylation | ISO | LIN7C (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of LIN7C gene | CTD | PMID:28589171 | Lin7c | Rat | sodium arsenite | decreases expression | ISO | LIN7C (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of LIN7C mRNA | CTD | PMID:38568856 | Lin7c | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of LIN7C mRNA | CTD | PMID:22110744 | Lin7c | Rat | sunitinib | increases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Sunitinib results in increased expression of LIN7C mRNA | CTD | PMID:31533062 | Lin7c | Rat | tetrachloromethane | affects expression | ISO | Lin7c (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of LIN7C mRNA | CTD | PMID:17484886 | Lin7c | Rat | thimerosal | increases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Thimerosal results in increased expression of LIN7C mRNA | CTD | PMID:27188386 | Lin7c | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of LIN7C mRNA | CTD | PMID:34492290 | Lin7c | Rat | topotecan | affects response to substance | ISO | LIN7C (Homo sapiens) | 6480464 | LIN7C protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | Lin7c | Rat | toxaphene | increases expression | EXP | | 6480464 | Toxaphene results in increased expression of LIN7C mRNA | CTD | PMID:23153324 | Lin7c | Rat | valproic acid | increases expression | ISO | LIN7C (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LIN7C mRNA | CTD | PMID:29154799 | Lin7c | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of LIN7C mRNA | CTD | PMID:23034163 | |