Nmur2 (neuromedin U receptor 2) - Rat Genome Database

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Pathways
Gene: Nmur2 (neuromedin U receptor 2) Rattus norvegicus
Analyze
Symbol: Nmur2
Name: neuromedin U receptor 2
RGD ID: 621155
Description: Enables neuropeptide receptor activity. Involved in regulation of sensory perception of pain. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human NMUR2 (neuromedin U receptor 2); INTERACTS WITH 17alpha-ethynylestradiol; alpha-Zearalanol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FM-4; G-protein coupled receptor TGR-1; G-protein-coupled receptor FM-4; neuromedin-U receptor 2; NMU-R2; Nmu2r
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81040,666,824 - 40,682,679 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1040,645,101 - 40,682,679 (-)EnsemblGRCr8
mRatBN7.21040,166,223 - 40,182,078 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1040,166,226 - 40,182,078 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1044,837,317 - 44,853,315 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01044,327,462 - 44,343,460 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01039,831,122 - 39,847,120 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01041,392,663 - 41,408,518 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1041,392,666 - 41,408,518 (-)Ensemblrn6Rnor6.0
Rnor_5.01041,219,613 - 41,235,468 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41041,471,179 - 41,485,043 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1039,485,666 - 39,501,503 (-)NCBICelera
RGSC_v3.11041,484,803 - 41,498,666 (-)NCBI
Cytogenetic Map10q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification and functional characterization of a novel subtype of neuromedin U receptor. Hosoya M, etal., J Biol Chem 2000 Sep 22;275(38):29528-32.
3. Identification of receptors for neuromedin U and its role in feeding. Howard AD, etal., Nature 2000 Jul 6;406(6791):70-4.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. Mori K, etal., EMBO J 2005 Jan 26;24(2):325-35. Epub 2005 Jan 6.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Pro-nociceptive effects of neuromedin U in rat. Yu XH, etal., Neuroscience. 2003;120(2):467-74.
Additional References at PubMed
PMID:8889548   PMID:10899166   PMID:15631899   PMID:17030627   PMID:17110433   PMID:18180374   PMID:18698496   PMID:21296417   PMID:23423171   PMID:24269937   PMID:30227148   PMID:30914203  
PMID:31069918  


Genomics

Comparative Map Data
Nmur2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81040,666,824 - 40,682,679 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1040,645,101 - 40,682,679 (-)EnsemblGRCr8
mRatBN7.21040,166,223 - 40,182,078 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1040,166,226 - 40,182,078 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1044,837,317 - 44,853,315 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01044,327,462 - 44,343,460 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01039,831,122 - 39,847,120 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01041,392,663 - 41,408,518 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1041,392,666 - 41,408,518 (-)Ensemblrn6Rnor6.0
Rnor_5.01041,219,613 - 41,235,468 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41041,471,179 - 41,485,043 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1039,485,666 - 39,501,503 (-)NCBICelera
RGSC_v3.11041,484,803 - 41,498,666 (-)NCBI
Cytogenetic Map10q22NCBI
NMUR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385152,391,546 - 152,405,279 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5152,391,542 - 152,433,368 (-)Ensemblhg38GRCh38
GRCh375151,771,107 - 151,784,840 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365151,751,302 - 151,765,017 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345151,751,302 - 151,765,017NCBI
Celera5147,846,463 - 147,860,200 (-)NCBICelera
Cytogenetic Map5q33.1NCBI
HuRef5146,910,244 - 146,923,981 (-)NCBIHuRef
CHM1_15151,203,649 - 151,217,384 (-)NCBICHM1_1
T2T-CHM13v2.05152,924,513 - 152,938,245 (-)NCBIT2T-CHM13v2.0
Nmur2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,915,816 - 55,931,813 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,915,813 - 55,931,836 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381156,024,990 - 56,040,987 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1156,024,987 - 56,041,010 (-)Ensemblmm10GRCm38
MGSCv371155,838,492 - 55,854,489 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361155,868,413 - 55,884,410 (-)NCBIMGSCv36mm8
Celera1160,806,131 - 60,822,188 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1133.39NCBI
Nmur2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554086,862,243 - 6,872,805 (-)NCBIChiLan1.0ChiLan1.0
NMUR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24147,616,118 - 147,630,526 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15145,755,664 - 145,770,047 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05147,811,260 - 147,825,659 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15153,813,004 - 153,826,791 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5153,811,055 - 153,827,176 (-)EnsemblpanPan2panpan1.1
NMUR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1456,994,731 - 57,018,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl456,994,886 - 57,008,384 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha456,885,634 - 56,909,684 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0457,442,833 - 57,466,883 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl457,430,442 - 57,456,458 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1457,258,890 - 57,282,940 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0457,369,114 - 57,393,157 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0457,860,086 - 57,885,818 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
NMUR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1670,659,563 - 70,673,347 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11670,659,732 - 70,672,346 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21676,522,957 - 76,535,804 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NMUR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12354,934,525 - 55,217,859 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2354,933,683 - 54,948,055 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603422,739,585 - 22,752,597 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nmur2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473336,597,431 - 36,611,439 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473336,597,310 - 36,612,589 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Nmur2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1939,046,659 - 39,062,326 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Nmur2
116 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:30
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000018967
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103589345164140567Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103621155669161158Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103589326364653589Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2298480Eau7Experimental allergic uveoretinitis QTL 70.0049uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103550938380509383Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103589326352293000Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880050Am10Aortic mass QTL 100.016aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)103950348784503487Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)103550938388177745Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Got62  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,173,747 - 40,173,901 (+)MAPPERmRatBN7.2
Rnor_6.01041,400,188 - 41,400,341NCBIRnor6.0
Rnor_5.01041,227,138 - 41,227,291UniSTSRnor5.0
RGSC_v3.41041,476,712 - 41,476,866RGDRGSC3.4
RGSC_v3.41041,476,713 - 41,476,866UniSTSRGSC3.4
Celera1039,493,187 - 39,493,340UniSTS
RGSC_v3.11041,490,336 - 41,490,489RGD
RH 3.4 Map10432.5RGD
RH 3.4 Map10432.5UniSTS
Cytogenetic Map10q22UniSTS
D10Got203  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,180,373 - 40,180,612 (+)MAPPERmRatBN7.2
Rnor_6.01041,406,814 - 41,407,052NCBIRnor6.0
Rnor_5.01041,233,764 - 41,234,002UniSTSRnor5.0
RGSC_v3.41041,483,339 - 41,483,577UniSTSRGSC3.4
Celera1039,499,801 - 39,500,037UniSTS
Cytogenetic Map10q22UniSTS
RH144592  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,172,903 - 40,173,058 (+)MAPPERmRatBN7.2
Rnor_6.01041,399,344 - 41,399,498NCBIRnor6.0
Rnor_5.01041,226,294 - 41,226,448UniSTSRnor5.0
RGSC_v3.41041,475,869 - 41,476,023UniSTSRGSC3.4
Celera1039,492,343 - 39,492,497UniSTS
RH 3.4 Map10428.5UniSTS
Cytogenetic Map10q22UniSTS
AU046743  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21040,173,745 - 40,173,982 (+)MAPPERmRatBN7.2
Rnor_6.01041,400,186 - 41,400,422NCBIRnor6.0
Rnor_5.01041,227,136 - 41,227,372UniSTSRnor5.0
RGSC_v3.41041,476,711 - 41,476,947UniSTSRGSC3.4
Celera1039,493,185 - 39,493,421UniSTS
Cytogenetic Map10q22UniSTS
BM390633  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81040,667,289 - 40,667,497 (+)Marker Load Pipeline
mRatBN7.21040,166,688 - 40,166,896 (+)MAPPERmRatBN7.2
Rnor_6.01041,393,129 - 41,393,336NCBIRnor6.0
Rnor_5.01041,220,079 - 41,220,286UniSTSRnor5.0
RGSC_v3.41041,469,654 - 41,469,861UniSTSRGSC3.4
Celera1039,486,132 - 39,486,339UniSTS
RH 3.4 Map10426.2UniSTS
Cytogenetic Map10q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 1 4 78 9 25 3 7 3 1 31 13 2 75 5 75 22 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000018967   ⟹   ENSRNOP00000018967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1040,666,827 - 40,682,679 (-)Ensembl
mRatBN7.2 Ensembl1040,166,226 - 40,182,078 (-)Ensembl
Rnor_6.0 Ensembl1041,392,666 - 41,408,518 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000153674   ⟹   ENSRNOP00000110811
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1040,645,101 - 40,682,679 (-)Ensembl
RefSeq Acc Id: NM_022275   ⟹   NP_071611
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81040,666,824 - 40,682,679 (-)NCBI
mRatBN7.21040,166,223 - 40,182,078 (-)NCBI
Rnor_6.01041,392,663 - 41,408,518 (-)NCBI
Rnor_5.01041,219,613 - 41,235,468 (-)NCBI
RGSC_v3.41041,471,179 - 41,485,043 (-)RGD
Celera1039,485,666 - 39,501,503 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063269806   ⟹   XP_063125876
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81040,666,824 - 40,682,673 (-)NCBI
Protein Sequences
Protein RefSeqs NP_071611 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125876 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF82756 (Get FASTA)   NCBI Sequence Viewer  
  BAB13722 (Get FASTA)   NCBI Sequence Viewer  
  EDM04491 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018967
GenBank Protein Q9ESQ4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071611   ⟸   NM_022275
- UniProtKB: Q9JIB1 (UniProtKB/Swiss-Prot),   Q9ESQ4 (UniProtKB/Swiss-Prot),   A0A8L2QAH3 (UniProtKB/TrEMBL),   A6HEN6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018967   ⟸   ENSRNOT00000018967
RefSeq Acc Id: XP_063125876   ⟸   XM_063269806
- Peptide Label: isoform X1
- UniProtKB: Q9JIB1 (UniProtKB/Swiss-Prot),   Q9ESQ4 (UniProtKB/Swiss-Prot),   A0A8L2QAH3 (UniProtKB/TrEMBL),   A6HEN6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110811   ⟸   ENSRNOT00000153674
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ESQ4-F1-model_v2 AlphaFold Q9ESQ4 1-395 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621155 AgrOrtholog
BioCyc Gene G2FUF-25069 BioCyc
Ensembl Genes ENSRNOG00000014081 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000018967 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  NeuromedU_rcpt UniProtKB/Swiss-Prot
  NeuromedU_rcpt_2 UniProtKB/Swiss-Prot
  NMU-R2_C UniProtKB/Swiss-Prot
KEGG Report rno:64042 UniProtKB/Swiss-Prot
NCBI Gene 64042 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
  NEUROMEDIN-U RECEPTOR 2 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
  NmU-R2_C_term UniProtKB/Swiss-Prot
PhenoGen Nmur2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  NEUROMEDINUR UniProtKB/Swiss-Prot
  NEUROMEDNU2R UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014081 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0A8L2QAH3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M6D3_RAT UniProtKB/TrEMBL
  A6HEN6 ENTREZGENE, UniProtKB/TrEMBL
  NMUR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JIB1 ENTREZGENE
UniProt Secondary Q9JIB1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Nmur2  neuromedin U receptor 2  Nmu2r    Symbol updated 1299863 APPROVED
2004-02-26 Nmu2r  neuromedin U receptor 2      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Nmu2r  neuromedin U receptor 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the ventromedial hypothalamus 632965