Ttl (tubulin tyrosine ligase) - Rat Genome Database

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Gene: Ttl (tubulin tyrosine ligase) Rattus norvegicus
Analyze
Symbol: Ttl
Name: tubulin tyrosine ligase
RGD ID: 621113
Description: Enables tubulin-tyrosine ligase activity. Predicted to be involved in several processes, including positive regulation of mitotic cell cycle; post-translational protein modification; and regulation of metaphase plate congression. Predicted to act upstream of or within regulation of axon extension. Predicted to be active in spindle microtubule. Orthologous to human TTL (tubulin tyrosine ligase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: tubulin--tyrosine ligase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83136,752,025 - 136,781,758 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3136,752,000 - 136,781,758 (+)EnsemblGRCr8
mRatBN7.23116,298,813 - 116,328,538 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,298,797 - 116,328,538 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3120,196,066 - 120,222,520 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03128,791,655 - 128,818,105 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03126,452,127 - 126,478,585 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03121,596,773 - 121,626,581 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,596,791 - 121,624,048 (+)Ensemblrn6Rnor6.0
Rnor_5.03128,388,189 - 128,417,974 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43116,671,419 - 116,697,989 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3115,124,248 - 115,150,813 (+)NCBICelera
RGSC_v3.13116,576,991 - 116,603,562 (+)NCBI
Cytogenetic Map3q36NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
microtubule  (IEA)
spindle microtubule  (IBA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Tubulin tyrosine ligase: protein and mRNA expression in developing rat skeletal muscle. Arregui CO, etal., Dev Growth Differ 1997 Apr;39(2):167-78.
2. Characterization of the tubulin-tyrosine ligase. Ersfeld K, etal., J Cell Biol 1993 Feb;120(3):725-32.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12512949   PMID:15899979   PMID:25908662  


Genomics

Comparative Map Data
Ttl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83136,752,025 - 136,781,758 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3136,752,000 - 136,781,758 (+)EnsemblGRCr8
mRatBN7.23116,298,813 - 116,328,538 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,298,797 - 116,328,538 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3120,196,066 - 120,222,520 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03128,791,655 - 128,818,105 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03126,452,127 - 126,478,585 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03121,596,773 - 121,626,581 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,596,791 - 121,624,048 (+)Ensemblrn6Rnor6.0
Rnor_5.03128,388,189 - 128,417,974 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43116,671,419 - 116,697,989 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3115,124,248 - 115,150,813 (+)NCBICelera
RGSC_v3.13116,576,991 - 116,603,562 (+)NCBI
Cytogenetic Map3q36NCBI
TTL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382112,482,156 - 112,541,739 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2112,482,113 - 112,541,739 (+)Ensemblhg38GRCh38
GRCh372113,239,733 - 113,299,316 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362112,956,214 - 113,006,694 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342112,956,128 - 113,006,212NCBI
Celera2106,625,279 - 106,675,764 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2105,693,725 - 105,744,724 (+)NCBIHuRef
CHM1_12113,243,890 - 113,294,368 (+)NCBICHM1_1
T2T-CHM13v2.02112,908,795 - 112,968,389 (+)NCBIT2T-CHM13v2.0
Ttl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392128,907,867 - 128,938,203 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2128,907,862 - 128,938,203 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382129,065,947 - 129,096,283 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,065,942 - 129,096,283 (+)Ensemblmm10GRCm38
MGSCv372128,891,683 - 128,922,019 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362128,757,430 - 128,785,190 (+)NCBIMGSCv36mm8
Celera2130,293,491 - 130,323,607 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.65NCBI
Ttl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,743,751 - 1,774,512 (-)Ensembl
ChiLan1.0NW_0049554701,747,217 - 1,774,512 (-)NCBIChiLan1.0ChiLan1.0
TTL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,591,253 - 15,632,233 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,594,017 - 15,635,068 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,526,022 - 89,567,068 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A113,505,416 - 113,546,896 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,505,416 - 113,546,896 (+)EnsemblpanPan2panpan1.1
TTL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11736,735,836 - 36,770,292 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1736,735,788 - 36,767,016 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1736,504,890 - 36,539,300 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01737,511,436 - 37,545,848 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,511,409 - 37,545,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,649,169 - 36,683,745 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,703,448 - 36,738,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01736,917,312 - 36,951,900 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ttl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,096,219 - 82,130,048 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936783989,269 - 1,025,690 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936783989,269 - 1,024,537 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl343,977,265 - 44,022,635 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1343,980,634 - 44,022,611 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2345,574,533 - 45,617,612 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TTL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11415,500,417 - 15,540,252 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1415,500,520 - 15,538,184 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660804,140,168 - 4,186,856 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474912,549,969 - 12,595,490 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474912,550,017 - 12,595,397 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ttl
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15107,838,403 - 107,863,158 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ttl
400 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:53
Count of miRNA genes:46
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000024694
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)3125814931139636791Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
D3Uwm5  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83136,760,357 - 136,760,573 (+)Marker Load Pipeline
mRatBN7.23116,307,136 - 116,307,352 (+)MAPPERmRatBN7.2
Rnor_6.03121,605,101 - 121,605,316NCBIRnor6.0
Rnor_5.03128,409,454 - 128,409,669UniSTSRnor5.0
RGSC_v3.43116,679,702 - 116,679,917UniSTSRGSC3.4
RGSC_v3.43116,679,701 - 116,679,917RGDRGSC3.4
Celera3115,132,531 - 115,132,747UniSTS
RGSC_v3.13116,585,274 - 116,585,490RGD
Cytogenetic Map3q36UniSTS
RH133188  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83136,778,948 - 136,779,124 (+)Marker Load Pipeline
mRatBN7.23116,325,728 - 116,325,904 (+)MAPPERmRatBN7.2
Rnor_6.03121,623,772 - 121,623,947NCBIRnor6.0
Rnor_5.03128,390,823 - 128,390,998UniSTSRnor5.0
RGSC_v3.43116,698,294 - 116,698,469UniSTSRGSC3.4
Celera3115,151,118 - 115,151,293UniSTS
RH 3.4 Map3997.3UniSTS
Cytogenetic Map3q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000024694   ⟹   ENSRNOP00000024695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3136,752,010 - 136,781,758 (+)Ensembl
mRatBN7.2 Ensembl3116,298,835 - 116,328,538 (+)Ensembl
Rnor_6.0 Ensembl3121,596,791 - 121,624,048 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109318   ⟹   ENSRNOP00000090593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3136,752,058 - 136,776,422 (+)Ensembl
mRatBN7.2 Ensembl3116,298,797 - 116,328,538 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000143777   ⟹   ENSRNOP00000109763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3136,752,000 - 136,779,185 (+)Ensembl
RefSeq Acc Id: NM_138536   ⟹   NP_612545
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83136,752,075 - 136,778,644 (+)NCBI
mRatBN7.23116,298,854 - 116,325,424 (+)NCBI
Rnor_6.03121,596,818 - 121,623,467 (+)NCBI
Rnor_5.03128,388,189 - 128,417,974 (-)NCBI
RGSC_v3.43116,671,419 - 116,697,989 (+)RGD
Celera3115,124,248 - 115,150,813 (+)RGD
Sequence:
RefSeq Acc Id: XM_006234946   ⟹   XP_006235008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83136,752,030 - 136,781,758 (+)NCBI
mRatBN7.23116,298,813 - 116,328,538 (+)NCBI
Rnor_6.03121,596,773 - 121,626,581 (+)NCBI
Rnor_5.03128,388,189 - 128,417,974 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104213   ⟹   XP_038960141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83136,752,025 - 136,781,758 (+)NCBI
mRatBN7.23116,298,813 - 116,328,538 (+)NCBI
Protein Sequences
Protein RefSeqs NP_612545 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235008 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960141 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD10402 (Get FASTA)   NCBI Sequence Viewer  
  AAF18465 (Get FASTA)   NCBI Sequence Viewer  
  EDL80147 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024695
  ENSRNOP00000090593
GenBank Protein Q9QXJ0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_612545   ⟸   NM_138536
- UniProtKB: Q9Z1E5 (UniProtKB/Swiss-Prot),   Q9QXJ0 (UniProtKB/Swiss-Prot),   G3V8C8 (UniProtKB/TrEMBL),   A6HQ46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235008   ⟸   XM_006234946
- Peptide Label: isoform X1
- UniProtKB: Q9Z1E5 (UniProtKB/Swiss-Prot),   Q9QXJ0 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024695   ⟸   ENSRNOT00000024694
RefSeq Acc Id: XP_038960141   ⟸   XM_039104213
- Peptide Label: isoform X2
- UniProtKB: Q9Z1E5 (UniProtKB/Swiss-Prot),   Q9QXJ0 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000090593   ⟸   ENSRNOT00000109318
Ensembl Acc Id: ENSRNOP00000109763   ⟸   ENSRNOT00000143777
Protein Domains
TTL

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QXJ0-F1-model_v2 AlphaFold Q9QXJ0 1-377 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692418
Promoter ID:EPDNEW_R2943
Type:initiation region
Name:Ttl_1
Description:tubulin tyrosine ligase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03121,596,796 - 121,596,856EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621113 AgrOrtholog
BioCyc Gene G2FUF-47927 BioCyc
Ensembl Genes ENSRNOG00000018205 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000024694 ENTREZGENE
  ENSRNOT00000109318 ENTREZGENE
Gene3D-CATH 3.40.50.11480 UniProtKB/Swiss-Prot
  ATP-grasp fold, B domain UniProtKB/Swiss-Prot
InterPro TTL/TTLL_fam UniProtKB/Swiss-Prot
  Tubulin-tyrosine_ligase UniProtKB/Swiss-Prot
KEGG Report rno:171572 UniProtKB/Swiss-Prot
NCBI Gene 171572 ENTREZGENE
PANTHER TUBULIN--TYROSINE LIGASE UniProtKB/Swiss-Prot
  TUBULIN--TYROSINE LIGASE UniProtKB/Swiss-Prot
Pfam TTL UniProtKB/Swiss-Prot
PhenoGen Ttl PhenoGen
PROSITE TTL UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018205 RatGTEx
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/Swiss-Prot
UniProt A0A8I6GIC1_RAT UniProtKB/TrEMBL
  A0ABK0LG40_RAT UniProtKB/TrEMBL
  A6HQ46 ENTREZGENE, UniProtKB/TrEMBL
  G3V8C8 ENTREZGENE, UniProtKB/TrEMBL
  Q9QXJ0 ENTREZGENE
  Q9Z1E5 ENTREZGENE
  TTL_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q9Z1E5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ttl  tubulin tyrosine ligase      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ttl  tubulin tyrosine ligase      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression highly expressed in both undifferentiated myoblasts and cross-striated, contractile myotubes 634442