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Gene: Nucks1 (nuclear casein kinase and cyclin-dependent kinase substrate 1) Rattus norvegicus

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Symbol:

Nucks1

Name:

nuclear casein kinase and cyclin-dependent kinase substrate 1

RGD ID:

620993

Description:

Enables single-stranded DNA binding activity. Predicted to be involved in several processes, including DNA metabolic process; cellular response to X-ray; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within glucose homeostasis and positive regulation of insulin receptor signaling pathway. Predicted to be located in chromatin and nucleus. Predicted to be active in cytoplasm. Orthologous to human NUCKS1 (nuclear casein kinase and cyclin dependent kinase substrate 1); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cyclin-dependent kinase substrate; LOC100910083; Nucks; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; nuclear ubiquitous casein and cyclin-dependent kinases substrate; nuclear ubiquitous casein and cyclin-dependent kinases substrate-like; nuclear ubiquitous casein kinase 2; nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	45,897,275 - 45,926,491 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	45,897,248 - 45,923,101 (+)	Ensembl				GRCr8
mRatBN7.2	13	43,345,091 - 43,374,316 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	43,345,115 - 43,370,229 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	45,948,109 - 45,973,171 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	47,236,246 - 47,261,320 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	44,501,087 - 44,526,215 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	48,679,726 - 48,709,663 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	48,679,774 - 48,705,575 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	53,753,029 - 53,782,671 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	142,904,062 - 142,905,783 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	43,682,215 - 43,706,828 (+)	NCBI		Celera
RGSC_v3.1	6	142,910,248 - 142,911,961 (+)	NCBI
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atrial fibrillation (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine (EXP)

17alpha-ethynylestradiol (ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-fluorouracil (ISO)

aconitine (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aflatoxin M1 (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

azoxystrobin (EXP)

benzo[e]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

bortezomib (ISO)

Brodifacoum (EXP)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cadmium sulfate (ISO)

caffeine (ISO)

calciol (ISO)

carbon nanotube (ISO)

chloropicrin (ISO)

chlorpyrifos (EXP,ISO)

clofibrate (ISO)

cobalt dichloride (ISO)

cocaine (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

CU-O LINKAGE (ISO)

cycloheximide (ISO)

deoxynivalenol (ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethanol (ISO)

finasteride (EXP)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

glyphosate (EXP)

heroin (ISO)

hexadecanoic acid (ISO)

hydrogen peroxide (ISO)

imidacloprid (EXP)

lipopolysaccharide (ISO)

lithium atom (ISO)

lithium hydride (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methapyrilene (EXP,ISO)

methyl methanesulfonate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nefazodone (EXP)

nickel dichloride (EXP)

okadaic acid (ISO)

oxaliplatin (EXP)

paracetamol (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propanal (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

rotenone (EXP)

Salinomycin (ISO)

SB 431542 (ISO)

selenium atom (ISO)

senecionine (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

Soman (EXP)

tamoxifen (ISO)

tetrachloromethane (ISO)

thiabendazole (EXP)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

topotecan (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to X-ray (ISO)

chromatin organization (ISO)

DNA damage response (IEA)

DNA repair (IEA)

double-strand break repair via homologous recombination (IBA,ISO)

glucose homeostasis (ISO)

interstrand cross-link repair (IBA,ISO)

intracellular glucose homeostasis (ISO)

positive regulation of insulin receptor signaling pathway (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of DNA replication (ISO)

regulation of DNA strand elongation (ISO)

regulation of insulin receptor signaling pathway (ISO)

replication fork processing (ISO)

Cellular Component

chromatin (ISO)

chromosome (IEA)

cytoplasm (IBA,ISO)

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (IEA,ISO,TAS)

Molecular Function

chromatin binding (ISO)

DNA-binding transcription factor binding (ISO)

double-stranded DNA binding (IBA,ISO,NAS,TAS)

protein binding (ISO)

single-stranded DNA binding (IBA,IDA,TAS)

transcription coactivator activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	A putative DNA-binding domain in the NUCKS protein.	Grundt K, etal., Arch Biochem Biophys 2002 Nov 15;407(2):168-75.
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	The phosphate groups of the high mobility group like protein P1 strengthens its affinity for DNA.	Ostvold AC, etal., Biochem Biophys Res Commun. 1992 Jun 30;185(3):1091-7.
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8.	Consequences of CK2 signaling to the nuclear matrix.	Yu S, etal., Mol Cell Biochem 2001 Nov;227(1-2):67-71.

Additional References at PubMed

PMID:1298022	PMID:3000779	PMID:11298763	PMID:15489334	PMID:15632090	PMID:16641100	PMID:17604136	PMID:22681889	PMID:24140890	PMID:24931609	PMID:25116364	PMID:26205492
PMID:26323318

Genomics

Comparative Map Data

Nucks1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	45,897,275 - 45,926,491 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	45,897,248 - 45,923,101 (+)	Ensembl				GRCr8
mRatBN7.2	13	43,345,091 - 43,374,316 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	43,345,115 - 43,370,229 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	45,948,109 - 45,973,171 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	47,236,246 - 47,261,320 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	44,501,087 - 44,526,215 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	48,679,726 - 48,709,663 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	48,679,774 - 48,705,575 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	53,753,029 - 53,782,671 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	142,904,062 - 142,905,783 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	43,682,215 - 43,706,828 (+)	NCBI		Celera
RGSC_v3.1	6	142,910,248 - 142,911,961 (+)	NCBI
Cytogenetic Map	13	q13	NCBI

NUCKS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	205,712,822 - 205,750,182 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	205,712,822 - 205,750,270 (-)	Ensembl			hg38	GRCh38
GRCh37	1	205,681,950 - 205,719,310 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	203,953,732 - 203,985,916 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	202,418,765 - 202,450,950	NCBI
Celera	1	178,818,181 - 178,855,596 (-)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	176,846,753 - 176,884,077 (-)	NCBI		HuRef
CHM1_1	1	207,105,250 - 207,142,880 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	204,977,487 - 205,014,861 (-)	NCBI		T2T-CHM13v2.0

Nucks1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	131,838,196 - 131,864,059 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	131,838,272 - 131,864,059 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	131,910,458 - 131,936,321 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	131,910,534 - 131,936,321 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	133,807,035 - 133,832,898 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	133,738,080 - 133,760,518 (+)	NCBI		MGSCv36	mm8
Celera	1	134,514,788 - 134,540,507 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	57.22	NCBI

Nucks1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	41,417,983 - 41,449,177 (-)	Ensembl
ChiLan1.0	NW_004955406	41,412,855 - 41,448,551 (-)	NCBI	ChiLan1.0	ChiLan1.0

NUCKS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	43,619,184 - 43,656,371 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	43,584,722 - 43,621,726 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	181,322,760 - 181,359,321 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	185,606,796 - 185,642,984 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	185,606,796 - 185,642,984 (-)	Ensembl			panPan2	panpan1.1

NUCKS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	2,157,109 - 2,188,543 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	2,160,233 - 2,170,560 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	2,247,878 - 2,281,320 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	2,151,877 - 2,185,307 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	2,147,942 - 2,185,365 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	2,146,543 - 2,180,007 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	2,538,314 - 2,571,710 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	2,738,657 - 2,772,120 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Nucks1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	69,472,785 - 69,487,729 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936557	6,713,095 - 6,722,808 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936557	6,713,065 - 6,728,011 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NUCKS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	66,398,227 - 66,435,517 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	66,398,845 - 66,435,548 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	72,663,549 - 72,701,529 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NUCKS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	23,597,210 - 23,634,262 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	23,597,464 - 23,629,169 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	24,292,825 - 24,330,137 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nucks1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624807	5,495,770 - 5,535,907 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Nucks1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	3,908,113 - 3,936,761 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Nucks1
72 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	336
Count of miRNA genes:	200
Interacting mature miRNAs:	227
Transcripts:	ENSRNOT00000075674
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	11866254	56866254	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	24853925	69853925	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
1300163	Cardf1	Cardiac cell morphology QTL 1	4.18		aorta morphology trait (VT:0000272)	artery lesion measurement (CMO:0000975)	13	12448421	47969993	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	17468282	62468282	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	12384320	57384320	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
61339	Bp24	Blood pressure QTL 24		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	6002008	47359539	Rat
2303032	Bp328	Blood pressure QTL 328			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	43736327	47969993	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	24335432	55601132	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37087983	82087983	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
2302275	Gluco37	Glucose level QTL 37	3.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	13	12448421	48744906	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	26244808	71244808	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	33794096	78794096	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	34834947	79834947	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	33794096	60914504	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	3088755	48088755	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	26244808	71244808	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	17711336	62711336	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	11866254	56866254	Rat

Markers in Region

RH131493

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	43,346,742 - 43,346,926 (+)	MAPPER	mRatBN7.2
mRatBN7.2	17	6,288,728 - 6,288,911 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	6,690,477 - 6,690,659	NCBI	Rnor6.0
Rnor_6.0	13	48,681,415 - 48,681,598	NCBI	Rnor6.0
Rnor_5.0	13	53,754,936 - 53,755,119	UniSTS	Rnor5.0
Rnor_5.0	17	8,894,850 - 8,895,032	UniSTS	Rnor5.0
RGSC_v3.4	17	12,219,543 - 12,219,725	UniSTS	RGSC3.4
Celera	17	6,398,439 - 6,398,621	UniSTS
Celera	13	43,683,783 - 43,683,966	UniSTS
Cytogenetic Map	6	q33	UniSTS
Cytogenetic Map	17	p14	UniSTS

RH143279

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	136,595,009 - 136,595,145 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	143,661,333 - 143,661,468	NCBI	Rnor6.0
Rnor_6.0	6	143,504,256 - 143,504,391	NCBI	Rnor6.0
Rnor_5.0	6	152,603,380 - 152,603,515	UniSTS	Rnor5.0
Rnor_5.0	6	152,451,046 - 152,451,181	UniSTS	Rnor5.0
RGSC_v3.4	6	142,904,197 - 142,904,332	UniSTS	RGSC3.4
Celera	6	134,266,292 - 134,266,427	UniSTS
RH 3.4 Map	6	938.0	UniSTS
Cytogenetic Map	6	q33	UniSTS

RH138087

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	6	152,416,475 - 152,416,620	NCBI	Rnor5.0
Rnor_5.0	6	152,603,994 - 152,604,139	NCBI	Rnor5.0
Rnor_5.0	13	53,777,622 - 53,777,767	NCBI	Rnor5.0
RGSC_v3.4	6	142,904,812 - 142,904,956	UniSTS	RGSC3.4
Celera	6	134,266,907 - 134,267,051	UniSTS
Cytogenetic Map	6	q33	UniSTS

RH139043

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	136,595,011 - 136,595,166 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	143,661,335 - 143,661,489	NCBI	Rnor6.0
Rnor_6.0	6	143,504,258 - 143,504,412	NCBI	Rnor6.0
Rnor_5.0	6	152,603,382 - 152,603,536	UniSTS	Rnor5.0
Rnor_5.0	6	152,451,048 - 152,451,202	UniSTS	Rnor5.0
RGSC_v3.4	6	142,904,199 - 142,904,353	UniSTS	RGSC3.4
Celera	6	134,266,294 - 134,266,448	UniSTS
RH 3.4 Map	6	916.0	UniSTS
Cytogenetic Map	6	q33	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ237669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000075674 ⟹ ENSRNOP00000065540

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	45,897,248 - 45,923,101 (+)	Ensembl
mRatBN7.2 Ensembl	13	43,345,129 - 43,370,198 (+)	Ensembl
Rnor_6.0 Ensembl	13	48,679,774 - 48,705,575 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079707 ⟹ ENSRNOP00000074382

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	45,908,475 - 45,923,101 (+)	Ensembl
mRatBN7.2 Ensembl	13	43,356,296 - 43,370,229 (+)	Ensembl
Rnor_6.0 Ensembl	13	48,689,962 - 48,704,771 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107058 ⟹ ENSRNOP00000090620

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	45,908,817 - 45,923,101 (+)	Ensembl
mRatBN7.2 Ensembl	13	43,356,638 - 43,370,229 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112895 ⟹ ENSRNOP00000076606

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	43,345,115 - 43,370,229 (+)	Ensembl

RefSeq Acc Id:

NM_022799 ⟹ NP_073636

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	45,897,327 - 45,922,405 (+)	NCBI
mRatBN7.2	13	43,345,145 - 43,370,229 (+)	NCBI
Rnor_6.0	13	48,679,774 - 48,705,577 (+)	NCBI
Rnor_5.0	13	53,753,029 - 53,782,671 (+)	NCBI
RGSC_v3.4	6	142,904,062 - 142,905,783 (+)	RGD
Celera	13	43,682,215 - 43,706,828 (+)	NCBI

Sequence:

show sequence

GGGCTCGTCAGATCCAGGGACCCGAAACAAGCAGCCGCGGACTCTGAGAAGCCAGCAGCTCCGG
GCTTGGCAGCAGCGGCCCCGCCGGCCGGAGCGGGGGGGTGGGGCGCCGAGTGCGCGGGGAGGGG
GGTCCTGGTCCTCGTCTCCTCGACTTGGTCGCGCCTCGACAACGAACATGTCTCGGCCTGTCAG
AAATAGGAAGGTCGTTGATTACTCACAGTTTCAGGAGTCAGATGATGCAGACGAAGATTATGGA
AGAGATTCAGGCCCTCCTGCTAAGAAGATTCGGTCATCTCCCCGAGAGGCTAAAAATAAGAGGC
GATCTGGCAAAAATTCACAAGAAGACAGTGAAGACTCAGAAGAAAAAGATGTGAAGACCAAGAA
GGATGATTCTCACTCAGCAGAAGACAGTGAGGATGAAAAAGATGACCATAAAAGTGTACGCCAG
CAGCGGCAGGCAGCATCAAAAGCAGCTTCTAAGCAGAGAGAGATGCTCTTGGAAGATGTGGGCA
GCGAGGAGGAGCCGGAAGAAGATGATGAGGCGCCATTCCAGGAGAAAGATTCTGGCAGCGACGA
AGATTTCCTAATGGAGGACGACGATGATAGTGATTATGGCAGTTCAAAAAAGAAAAACAAAAAG
ATGGTTAAGAAGTCCAAACCTGAGAGGAAAGAAAAGAAAATGCCCAAACCCAGACTAAAGGCTA
CAGTGACACCAAGTCCAGTGAAAGGCAAGGGGAAAGTGGGTCGCCCCACGGCTTCAAAGACATC
AAAGGAAAAAACTCCTTCTCCCAAAGAAGAGGACGAGGAAGCAGAAAGCCCTCCAGAAAAGAAG
ACATCTGCAAGCCCCCCACTCGAGAAGTCTGGAGATGAAGGGTCTGAAGATGAAGCGGCATCTG
GGGAAGATTAAAAGTGATACTGGGGAGAGGTTTTATTAAAAAAACAAAACAAAAAAGGAAACCT
ATGTAGGACACGGTTTGGGCTGTGGCTTGACTCATGGGCTTTCAGTGCTATTTCATTTGTCTAG
AATAATGTTTTTCTCTCTACCATCTATCTTTCTCAAAACCATTGTATGCTGATGTGTTTAAGTT
GCCATTTTGTCTCAGTCTTTTCTCTGCCAGCCCCCCCACCCCCACGAAAGCCATGTCAATCAAT
CACTGGATTGACCATTTCATGTGTTAATAGCAGGAAGGAATGCCACGGCCGCACAGCAGTAAGA
TTTGAGGTGGGCGCTATGGAAGCTGCTTTTTGCTAGCAACTTGAACAATAATCAAAAACAAAAA
TCTAGAAAGGTTTTAATTAAACAGTTGCTTTTTCTTCTCCTGTACTTTTGACAGACCAGTTGTC
ATTTAACATGAGCTTATATGTCTAAACTGTAAATGTCAAAAAGAATCATGACTCTAAATTTGTC
CGGTGAGGCAGTTGGGAGGCGAACATGAATTCTGGGTTGCTAACTCAGTACGCAGTTACTCCCG
GGTGTGGAGGGAGGCCGTCCTGGAACTCAGTGTACTCGCTGTTCTCAGAGACTCGGGTCCACCG
GTTCTTTCGTCTTGATAATGGGCTTCTGTCTTTTCTTACTGGGCCACCAGAATGAGTCTTAATT
TCATATTTCATTCATGTTTTCATTGATTCAAGTTTTTAAAGTACATCCTGTTTTCTGGTAAAGT
TTTACCAATGGTCAAAAATTAAAAAGATTTCTTTGAATTTCAATGACAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006249797 ⟹ XP_006249859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	45,897,275 - 45,926,491 (+)	NCBI
mRatBN7.2	13	43,345,091 - 43,374,316 (+)	NCBI
Rnor_6.0	13	48,679,726 - 48,709,663 (+)	NCBI
Rnor_5.0	13	53,753,029 - 53,782,671 (+)	NCBI

Sequence:

show sequence

ATTTTCGGCTGGTTTGATTCATCCATTTTGAAGAGACGGGGGAGCGGGGGGCTCGTCAGATCCA
GGGACCCGAAACAAGCAGCCGCGGACTCTGAGAAGCCAGCAGCTCCGGGCTTGGCAGCAGCGGC
CCCGCCGGCCGGAGCGGGGGGGTGGGGCGCCGAGTGCGCGGGGAGGGGGGTCCTGGTCCTCGTC
TCCTCGACTTGGTCGCGCCTCGACAACGAACATGTCTCGGCCTGTCAGAAATAGGAAGGTCGTT
GATTACTCACAGTTTCAGGAGTCAGATGATGCAGACGAAGATTATGGAAGAGATTCAGGCCCTC
CTGCTAAGAAGATTCGGTCATCTCCCCGAGAGGCTAAAAATAAGAGGCGATCTGGCAAAAATTC
ACAAGAAGACAGTGAAGACTCAGAAGAAAAAGATGTGAAGACCAAGAAGGATGATTCTCACTCA
GCAGAAGACAGTGAGGATGAAAAAGATGACCATAAAAGTGTACGCCAGCAGCGGCAGGCAGCAT
CAAAAGCAGCTTCTAAGCAGAGAGAGATGCTCTTGGAAGATGTGGGCAGCGAGGAGGAGCCGGA
AGAAGATGATGAGGCGCCATTCCAGGAGAATTCTGGCAGCGACGAAGATTTCCTAATGGAGGAC
GACGATGATAGTGATTATGGCAGTTCAAAAAAGAAAAACAAAAAGATGGTTAAGAAGTCCAAAC
CTGAGAGGAAAGAAAAGAAAATGCCCAAACCCAGACTAAAGGCTACAGTGACACCAAGTCCAGT
GAAAGGCAAGGGGAAAGTGGGTCGCCCCACGGCTTCAAAGACATCAAAGGAAAAAACTCCTTCT
CCCAAAGAAGAGGACGAGGAAGCAGAAAGCCCTCCAGAAAAGAAGACATCTGCAAGCCCCCCAC
TCGAGAAGTCTGGAGATGAAGGGTCTGAAGATGAAGCGGCATCTGGGGAAGATTAAAAGTGATA
CTGGGGAGAGGTTTTATTAAAAAAACAAAACAAAAAAGGAAACCTATGTAGGACACGGTTTGGG
CTGTGGCTTGACTCATGGGCTTTCAGTGCTATTTCATTTGTCTAGAATAATGTTTTTCTCTCTA
CCATCTATCTTTCTCAAAACCATTGTATGCTGATGTGTTTAAGTTGCCATTTTGTCTCAGTCTT
TTCTCTGCCAGCCCCCCCACCCCCACGAAAGCCATGTCAATCAATCACTGGATTGACCATTTCA
TGTGTTAATAGCAGGAAGGAATGCCACGGCCGCACAGCAGTAAGATTGAGGGTGGGCGCTATGG
AAGCTGCTTTTTGCTAGCAACTTGAACAATAATCAAAAACAAAAATCTAGAAAGGTTTTAATTA
AACAGTTGCTTTTTCTTCTCCTGTACTTTTGACAGACCAGTTGTCATTTAACATGAGCTTATAT
GTCTAAACTGTAAATGTCAAAAAGAATCATGACTCTAAATTTGTCCGGTGAGGCAGTTGGGAGG
CGAACATGAATTCTGGGTTGCTAACTCAGTACGCAGTTACTCCCGGGTGTGGAGGGAGGCCGTC
CTGGAACTCAGTGTACTCGCTGTTCTCAGAGACTCGGGTCCACCGGTTCTTTCGTCTTGATAAT
GGGCTTCTGTCTTTTCTTACTGGGCCACCAGAATGAGTCTTAATTTCATATTTCATTCATGTTT
TCATTGATTCAAGTTTTTAAAGTACATCCTGTTTTCTGGTAAAGTTTTACCAATGGTCAAAAAT
TAAAAAGATTTCTTTGAATTTCAATGACAAGATGAGTCTACACCTCCCAGTGCATTTATTTCTT
CATAAGCTGACGATATCAAAATTTTAAGCGAATAAAGGTTGAGTTAGTGTGAAGCTTGGATATA
AAGGGTTGAGGTTTATCCTTTATGAATACAAATATTTGAAATGAACCATGCTGTTTTTATTGGA
GATAGAAACAGCTTTTTCCTTTTGATGTTTAAATCTTTCCTTCAGAGTAACAGGATAATAATCT
CACAACTTCTGCTGCTGCTTCCATTCTCTGGAGTCGTTTGCTTCTTAGTCCATCTGACCCCTCC
TTTCCATTCATGTTTGTTTTTAAAACAAGAGCCTGAGCCTCAGCGGGATGAGTGAGCTGTTGTA
GGGTGCCTATGTGCCATTGATAACCCTCTAGAACCTTAGCAGAGCGGCAAGGACAGATCAGAGC
TTTGCTCCTCCGCATTCAGGCCCCGTTCGCCAATAGACGCAGAGATTAGGGGTCCTAATGCTAC
TAAATTAAAGATTTGGTGGAGTAATTTCTGTATATTTTTCTGCACTTGAGCTAAATTTGCTTCC
TCAGTATTCTGCTTTTGTGTTTTTTAAGTGACATGTTTGTCTCAGACAATGTCATTTTCTTAAT
AGGTGTTCGTAGGACAAAGGGTTATTTAAGAAATATTTTTACTCTGGTTTTTAAGACACTTTAA
AGAACATTCTTAGATCTGCTTTAAAATAAATAAATGAATAAATAAATAAAACACCTAGTGGCAG
TTATTTTAACCCTGCACTGCTAATAAATGAGTATTAACATGGCCAAAAATAGAAACTTGAACAC
AAACAGTTGGATTATTGTATTCTGTAATGGGTTATATATATAGTTGTGAGCTGTGTAGTGGGTA
TTACAGATTATTCTGTTTGCTGTGGTGGGCTTGCTCAGGAACCCGTCCTTAAAGAAGAGACTCA
CCATCTCCACCAGGCATCTCCCTTTTAGAGGTTTATAATTCAGTCTACATTCCTAGTGACATTT
GGGCTTTTCTTAGGTTATGTTTTATGAAAAATTGTGGGTAGGGTCCCTTTCAACTTAAGCCTCA
AATTTTTTTAAGTCTCTTTAATAATCTGCATTAACATCTCTGATTTTATCTACCTATAATTGAG
AAATAATGCTATCTTCTAGGTTACTTGTGTAAAAGATGTGTCGATTGGACTTCTTGTTTAGAAT
CCCTTTTAAAACCAATTCATTAGATTGAAGATATATTTTCTAATTACAGGTCGGTTGGGTTAAT
GGTGTCTCAAGTGAGCACACAGGCTCTAAGTGACCTTTGTTTTCACTTTTTTTTAGTGGTTTAT
AACACTCTGGTCTTCCCTTCAAATCATGCATGCAAATAAGGAAGACTTAACGTGCTCAACTGGA
AACAGGTGCTCAGCAGTTAGGTGTAGTAACACACGAGGATATGTCCGTGTGTTCATAATGACTG
GCCCTTGACACCTCCATGGCTTACTCTCCGTCCTCTTTCTTTCGTCTTTTTTTCTCTACTGTGC
CTATAGTGAAGTGGCAATGTATTCACTGTCTTAGTTTGCAGTGCTCAGGAACGGAATGTTCGTT
TGAAGGTCTTGTCTGTTACGGAAGCTCAGCTAGGTTTACCTCTTTAATAGATGCAGTGGCTCAG
CTAACACTACATTCTAGTTCTCCAGACTCTGGTTAAAGCCTTTGTCTCCTCCTTCGAGAAATGG
TAGCCTCTGTGTTACCCAGTGGCAATTTACTGCTGCTTTTAGCCATCCACCACTGATGGGATTT
GGGAGAGAGGACCCAAAGGGTGTATTTTAAATATCTGCTGAATCACTTACCTGCTTTCAGTACC
TCCCTCTCCATAGTAACCTTAGAAAGGAAAACTAATGGTAGGATGAACGTTTTTGTTTTTGTTT
TTTCTAGAGTAGTGAGAAAATCCCCCACAAACATCTTACCAAAACCCCAGTATTTTGTGTACCC
CAGGCTGGCCTCAAACTTGCTACATGGCTGATCGTAAACTCATTGTTTTGTTTTTTTCAAAATA
ACTGATTTTTCTTCTGTCTTCAATGTTTATATATGGTACTAGTTCAGATAGCATTTTCTTCCAT
ATAAAAATCAGTGGAATTTGAGGTTATAATCTAGAAGGACTTTTGATTAATGGTCAATTGATCT
TGAGGCCTGGTTTTAGTTTGTAGTCCAGCTGGGAGTCCTCCTCCCCCTCCCCCTCACACTGCTA
GGATTAATGCCACCATGACCGGTGACACTTTTCAAAATGGGCTTTGTTTATTTTTATGTCCACA
AATGTGTAGGTGGCAGGTTGGAAAGGGAAGTAGTGTAAACAAAACTCAGGTTTAGGGGCCCCTG
CCAGAGCAGACGAGAATAGAAGCAGCAGAAAGCTTGCTGCTGTGGAATCAGTGCCTGTTTGGAC
AGTTCTCTACTGCTAGCACCAGAAGCCACACCAGAACATTGCCACCTGTGACTGGGTAAGAAGA
AATGCAGGCTAGGCACTTCATGGTGTGGGGATGGAGGTCAGAAACACAGTACACGCTTCTTGCC
AAAGGGGAGGGAAAGTTAAAGCCACTGGTTGCTCTTGAGGGTAGAATATTGTTATTTTCTCTCT
GGAGGAAGCTGCTGAGTTACTTGAAGATGGGGATTGTGGGGTTTTTGTTTTTTTGAGCATTGTG
ATGCCAAGCTGTCAATAGCCATGTTGCTATTTGAACCTCCTTTCCCTTTTGTCTTAGAAAATAC
ATGATTCTGAATATCAAATCCATAGGTTATACTTTTGTTCAAAGCCTAATTCACAGTAGTGTGA
TTGTACTAAACACTAGGAGGGTCCCATATGCCTGCCTGTCGCCATGCCAATGAAGAATGAACTG
GCGACATCTGAGCATGCTCTGTGACTGTAGGGCATCACAGTTGTGCAGACACTTTGTATATTGG
GTGAGGGGGGTTTTCTAGTTTATGGGGGAGGATGAATTGATTTGGGGGGGTCATTTTTTCCCCC
AGTTTTGGGGCTTTTTGTTTTGGTTTGTTTTGGGGTTTTTTGTTTTTGTTTTTTTTTTTTTTTT
TTGGGTTGTTTCTGGTTTTGCTTTTTGTGGAGGGTTGGGGAAGTATAGTACTCAGTTATGCCCT
AAAAATAACATGTATAAAACCCTGAAGTGTGACGTGGGTATGTGTGAGTGTGTATTTGTAAATG
TCTGGCAATTCAACCTTTGTCTTCTGGAAGTTAGTGATTTTCCCCCGTTCTCTGGAAGTATTTG
TTACAAGATTTGTAAACAAAAGCTCTACATAGTCGGTGTACCATGAACATATTGCAGCAAACCT
TAGATGCTTCATTCCTGCAAGGCTTAAGACGTCACCAGGTTGCTCAGCCGCCACGATCAGTTTG
CCTTGATTCATCTTTTAGATTTAATTCGCCAGTTCTAAAGACTCCTAGTCTTCCTCGGTTTTAG
TCTTTAATCTTTCGTGTTCTGAGCAGAAAGTGAGAAAGCTAGCCTGTCTGAGGCCATGGGCTGA
GAACCTGGCATCGTTTTCTTCATACTGCAGTGTGGCTTGATACATGATTAAACATCAGAGTGCT
GGGCGTTCTTGCAATACCTTAGCAGTGCTGAAATCTGCAGCCTGGTACTAAGGAAGCTAAAGTT
GGAATGTAACCACTTTAAGGTTTTTTTTTTTTTCTTTAATTTAAATGAAACCGAGTTGGACATG
GTTTTGTTGACCATGTTCATGATTTATAGATGCAACATGCATTGGTGGACTCATGTGATGGTCT
GACGTGATACTTCGTTTCGTACATTTACCTATCCCGGTCTGTACACATTTGCTTAAACAACAAC
AAACTCCTGCCTTGCTCCAACTGAAGGATTTCCAGGACTGCTGTCGGCTCCTGAACTCTGTTTT
AAGTATGCGTGTCCTTTGCTTGTATTTTGTACTAAGAAATAAGGAAAAGAACCCCTTTTTGTTG
AGCATGTTGGTATTGTCCCCCCCCCCCCCTTTTTTTTTCCTCTTGGGGACATATGAAGCAAGTT
ACTCTTTTCTGTATCCTTTTCTTTTGTAAACCTTTTGGTTTGTTTTGTTTAAAAATGGCTTTAT
AAAAGGGCTTTTGTAACCCA

hide sequence

RefSeq Acc Id:

XM_063272581 ⟹ XP_063128651

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	45,897,386 - 45,920,318 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_073636	(Get FASTA)	NCBI Sequence Viewer
	XP_006249859	(Get FASTA)	NCBI Sequence Viewer
	XP_063128651	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78818	(Get FASTA)	NCBI Sequence Viewer
	CAC20862	(Get FASTA)	NCBI Sequence Viewer
	EDL89067	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000065540
	ENSRNOP00000076606.1
GenBank Protein	Q9EPJ0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_073636 ⟸ NM_022799

- UniProtKB:

Q9EPJ0 (UniProtKB/Swiss-Prot), A0A8L2UNR4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEK
DVKTKKDDSHSAEDSEDEKDDHKSVRQQRQAASKAASKQREMLLEDVGSEEEPEEDDEAPFQEK
DSGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRP
TASKTSKEKTPSPKEEDEEAESPPEKKTSASPPLEKSGDEGSEDEAASGED

hide sequence

RefSeq Acc Id:	XP_006249859 ⟸ XM_006249797
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2UNR4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEK DVKTKKDDSHSAEDSEDEKDDHKSVRQQRQAASKAASKQREMLLEDVGSEEEPEEDDEAPFQEN SGSDEDFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPT ASKTSKEKTPSPKEEDEEAESPPEKKTSASPPLEKSGDEGSEDEAASGED hide sequence

Ensembl Acc Id:

ENSRNOP00000074382 ⟸ ENSRNOT00000079707

Ensembl Acc Id:

ENSRNOP00000065540 ⟸ ENSRNOT00000075674

Ensembl Acc Id:

ENSRNOP00000090620 ⟸ ENSRNOT00000107058

Ensembl Acc Id:

ENSRNOP00000076606 ⟸ ENSRNOT00000112895

RefSeq Acc Id:	XP_063128651 ⟸ XM_063272581
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9EPJ0-F1-model_v2	AlphaFold	Q9EPJ0	1-243	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698803

Promoter ID:

EPDNEW_R9328

Type:

initiation region

Name:

Nucks1_1

Description:

nuclear casein kinase and cyclin-dependent kinase substrate 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	48,679,746 - 48,679,806	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620993	AgrOrtholog
BioCyc Gene	G2FUF-18332	BioCyc
Ensembl Genes	ENSRNOG00000047287	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000075674	ENTREZGENE
	ENSRNOT00000112895.1	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7128528	IMAGE-MGC_LOAD
InterPro	HR_DNA-Binding_Protein	UniProtKB/Swiss-Prot
KEGG Report	rno:64709	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93427	IMAGE-MGC_LOAD
NCBI Gene	64709	ENTREZGENE
PANTHER	PTHR15361:SF1	UniProtKB/Swiss-Prot
	RAD51/NUKS-INTERACTING PROTEIN	UniProtKB/Swiss-Prot
PhenoGen	Nucks1	PhenoGen
RatGTEx	ENSRNOG00000047287	RatGTEx
UniProt	A0A0G2K7X3_RAT	UniProtKB/TrEMBL
	A0A8I6ANM3_RAT	UniProtKB/TrEMBL
	A0A8L2UNR4	ENTREZGENE, UniProtKB/TrEMBL
	NUCKS_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-04-17	Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	LOC100910083	nuclear ubiquitous casein and cyclin-dependent kinases substrate-like	Data merged from RGD:6499947	737654	PROVISIONAL
2012-07-05	LOC100910083	nuclear ubiquitous casein and cyclin-dependent kinases substrate-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-02-22	Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1	Nucks	nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Nucks	nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate			Symbol and Name status set to approved	1299863	APPROVED
2004-04-20		nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate	Nucks	nuclear ubiquitous casein kinase 2	Name updated	625702	PROVISIONAL
2002-08-07	Nucks	nuclear ubiquitous casein kinase 2			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	located in nucleus in interphase cells and throughout cytoplasm during mitosis	1298022
gene_domains	contains a GRP domain in the DNA binding AT hook	1298022
gene_expression	expressed in all tissues and cell types examined	1298022
gene_physical_interaction	phosphorylation inhibits binding in metaphase cells	1298022
gene_process	substrate for several kinases involved in cell growth and survival	1298022
gene_transcript	three transcripts of 1.5, 2.2, 7.0 kb	1298022

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD