Rtn1 (reticulon 1) - Rat Genome Database

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Gene: Rtn1 (reticulon 1) Rattus norvegicus
Analyze
Symbol: Rtn1
Name: reticulon 1
RGD ID: 620986
Description: Predicted to be involved in endoplasmic reticulum tubular network formation; negative regulation of amyloid-beta formation; and nervous system development. Located in smooth endoplasmic reticulum. Orthologous to human RTN1 (reticulon 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neuroendocrine-specific protein; Nsp; reticulon-1; S-rex
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8696,499,137 - 96,719,340 (-)NCBIGRCr8
mRatBN7.2690,763,212 - 90,983,436 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl690,763,216 - 90,983,436 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx691,133,739 - 91,354,049 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0691,433,206 - 91,653,513 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0690,866,371 - 91,081,461 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0694,951,016 - 95,177,477 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl694,951,020 - 95,061,174 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06104,395,865 - 104,615,609 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4694,397,061 - 94,682,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1694,400,519 - 94,685,764 (-)NCBI
Celera689,223,752 - 89,441,412 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
amphotericin B  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
Butylbenzyl phthalate  (EXP)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlormequat chloride  (EXP)
chlorpyrifos  (ISO)
cobalt dichloride  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
dibutyl phthalate  (EXP)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (EXP)
isotretinoin  (ISO)
ivermectin  (ISO)
lithium chloride  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (ISO)
trichostatin A  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Intracellular compartmentalization of two differentially spliced s-rex/NSP mRNAs in neurons. Baka ID, etal., Mol Cell Neurosci 1996 Apr;7(4):289-303.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons. Kaya L, etal., Biochim Biophys Acta. 2013 Jun;1833(6):1421-33. doi: 10.1016/j.bbamcr.2013.02.012. Epub 2013 Feb 27.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Rat and chicken s-rex/NSP mRNA: nucleotide sequence of main transcripts and expression of splice variants in rat tissues. Ninkina NN, etal., Gene 1997 Jan 15;184(2):205-10.
8. A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family. Oertle T, etal., FASEB J 2003 Jul;17(10):1238-47.
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Differential display identifies neuroendocrine-specific protein-A (NSP-A) and interferon-inducible protein 10 (IP-10) as ethanol-responsive genes in the fetal rat brain. Yang J and Zoeller RT, Brain Res Dev Brain Res 2002 Oct 20;138(2):117-33.
Additional References at PubMed
PMID:9560466   PMID:12036513   PMID:12873973   PMID:17684057   PMID:26192016   PMID:28981095   PMID:29476059   PMID:30352262   PMID:30361391   PMID:31002913   PMID:33372676  


Genomics

Comparative Map Data
Rtn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8696,499,137 - 96,719,340 (-)NCBIGRCr8
mRatBN7.2690,763,212 - 90,983,436 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl690,763,216 - 90,983,436 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx691,133,739 - 91,354,049 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0691,433,206 - 91,653,513 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0690,866,371 - 91,081,461 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0694,951,016 - 95,177,477 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl694,951,020 - 95,061,174 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06104,395,865 - 104,615,609 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4694,397,061 - 94,682,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1694,400,519 - 94,685,764 (-)NCBI
Celera689,223,752 - 89,441,412 (-)NCBICelera
Cytogenetic Map6q24NCBI
RTN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381459,595,976 - 59,870,776 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1459,595,976 - 59,870,776 (-)EnsemblGRCh38hg38GRCh38
GRCh371460,062,694 - 60,337,494 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361459,132,447 - 59,407,310 (-)NCBINCBI36Build 36hg18NCBI36
Build 341459,132,446 - 59,264,184NCBI
Celera1440,111,786 - 40,386,796 (-)NCBICelera
Cytogenetic Map14q23.1NCBI
HuRef1440,226,493 - 40,501,076 (-)NCBIHuRef
CHM1_11460,000,887 - 60,276,505 (-)NCBICHM1_1
T2T-CHM13v2.01453,802,909 - 54,078,046 (-)NCBIT2T-CHM13v2.0
Rtn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391272,258,523 - 72,455,828 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1272,258,526 - 72,455,828 (-)EnsemblGRCm39 Ensembl
GRCm381272,211,749 - 72,409,054 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1272,211,752 - 72,409,054 (-)EnsemblGRCm38mm10GRCm38
MGSCv371273,312,739 - 73,509,926 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361273,130,590 - 73,327,777 (-)NCBIMGSCv36mm8
Celera1273,325,053 - 73,524,502 (-)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1230.2NCBI
Rtn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546613,290,419 - 13,454,387 (-)NCBIChiLan1.0ChiLan1.0
RTN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21560,728,297 - 61,002,261 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11459,944,811 - 60,218,775 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01440,198,279 - 40,472,255 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11458,463,335 - 58,737,309 (-)NCBIpanpan1.1PanPan1.1panPan2
RTN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1834,810,127 - 35,029,201 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl834,810,342 - 35,033,330 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha834,570,781 - 34,595,578 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0835,045,762 - 35,265,091 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl835,045,769 - 35,265,064 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1834,663,165 - 34,687,986 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0834,732,285 - 34,757,112 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0835,099,496 - 35,124,329 (-)NCBIUU_Cfam_GSD_1.0
Rtn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864070,033,442 - 70,258,046 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364953,933,605 - 4,158,571 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364953,933,652 - 4,158,269 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RTN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1188,704,260 - 188,926,054 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11188,704,260 - 188,925,855 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21209,727,826 - 209,941,920 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RTN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12436,821,989 - 37,092,718 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605325,071,786 - 25,339,134 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rtn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473441,274,546 - 41,530,090 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473441,274,072 - 41,529,134 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rtn1
1426 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:185
Count of miRNA genes:88
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000006373, ENSRNOT00000072262
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat

Markers in Region
D6Rat124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2690,871,403 - 90,871,645 (+)MAPPERmRatBN7.2
Rnor_6.0695,059,735 - 95,059,976NCBIRnor6.0
Rnor_5.06104,502,088 - 104,502,329UniSTSRnor5.0
Celera689,331,779 - 89,332,020UniSTS
SHRSP x BN Map655.6199RGD
SHRSP x BN Map655.6199UniSTS
Cytogenetic Map6q24UniSTS
RH130382  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2690,763,273 - 90,763,478 (+)MAPPERmRatBN7.2
Rnor_6.0694,951,074 - 94,951,278NCBIRnor6.0
Rnor_5.06104,395,923 - 104,396,127UniSTSRnor5.0
RGSC_v3.4694,397,119 - 94,397,323UniSTSRGSC3.4
Celera689,223,810 - 89,224,014UniSTS
RH 3.4 Map6652.7UniSTS
Cytogenetic Map6q24UniSTS
AU048830  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2690,858,936 - 90,859,098 (+)MAPPERmRatBN7.2
Rnor_6.0695,045,653 - 95,045,814NCBIRnor6.0
Rnor_5.06104,490,140 - 104,490,301UniSTSRnor5.0
Celera689,319,392 - 89,319,553UniSTS
Cytogenetic Map6q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 19
Medium 1 23 5 55 27
Low 2 20 46 30 14 30 8 11 35 14 11 8
Below cutoff 11 11 11

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006373   ⟹   ENSRNOP00000006373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl690,763,220 - 90,791,976 (-)Ensembl
Rnor_6.0 Ensembl694,951,020 - 94,980,004 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000072262   ⟹   ENSRNOP00000064845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl690,770,147 - 90,983,436 (-)Ensembl
Rnor_6.0 Ensembl694,951,776 - 95,061,174 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118381   ⟹   ENSRNOP00000087943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl690,763,216 - 90,983,436 (-)Ensembl
RefSeq Acc Id: NM_053865   ⟹   NP_446317
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8696,499,137 - 96,719,340 (-)NCBI
mRatBN7.2690,763,219 - 90,983,436 (-)NCBI
Rnor_6.0694,951,016 - 95,177,477 (-)NCBI
Rnor_5.06104,395,865 - 104,615,609 (-)NCBI
RGSC_v3.4694,397,061 - 94,682,308 (-)RGD
Celera689,223,752 - 89,441,412 (-)RGD
Sequence:
RefSeq Acc Id: XM_008764690   ⟹   XP_008762912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8696,499,137 - 96,528,200 (-)NCBI
mRatBN7.2690,763,212 - 90,792,050 (-)NCBI
Rnor_6.0694,951,019 - 94,980,032 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_446317   ⟸   NM_053865
- UniProtKB: Q64548 (UniProtKB/Swiss-Prot),   Q64547 (UniProtKB/Swiss-Prot),   A0A8I6GGJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762912   ⟸   XM_008764690
- Peptide Label: isoform X1
- UniProtKB: A6HC34 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006373   ⟸   ENSRNOT00000006373
RefSeq Acc Id: ENSRNOP00000064845   ⟸   ENSRNOT00000072262
RefSeq Acc Id: ENSRNOP00000087943   ⟸   ENSRNOT00000118381
Protein Domains
Reticulon

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64548-F1-model_v2 AlphaFold Q64548 1-777 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694659
Promoter ID:EPDNEW_R5180
Type:initiation region
Name:Rtn1_1
Description:reticulon 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0694,980,004 - 94,980,064EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620986 AgrOrtholog
BioCyc Gene G2FUF-37152 BioCyc
Ensembl Genes ENSRNOG00000004794 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006373.5 UniProtKB/Swiss-Prot
  ENSRNOT00000072262.4 UniProtKB/TrEMBL
  ENSRNOT00000118381 ENTREZGENE
  ENSRNOT00000118381.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.2480 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Reticulon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RTN1-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116644 UniProtKB/Swiss-Prot
NCBI Gene 116644 ENTREZGENE
PANTHER RETICULON-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RETICULON-LIKE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Reticulon UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rtn1 PhenoGen
PROSITE RETICULON UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004794 RatGTEx
UniProt A0A8I6GGJ4 ENTREZGENE, UniProtKB/TrEMBL
  A6HC33_RAT UniProtKB/TrEMBL
  A6HC34 ENTREZGENE, UniProtKB/TrEMBL
  M0R608_RAT UniProtKB/TrEMBL
  Q64547 ENTREZGENE
  Q64548 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q64547 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Rtn1  reticulon 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Rtn1  reticulon 1      Symbol and Name status set to provisional 70820 PROVISIONAL