Hnrnph1 (heterogeneous nuclear ribonucleoprotein H1) - Rat Genome Database

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Gene: Hnrnph1 (heterogeneous nuclear ribonucleoprotein H1) Rattus norvegicus
Analyze
Symbol: Hnrnph1 (Ensembl: Hnrnph2)
Name: heterogeneous nuclear ribonucleoprotein H1 (Ensembl:heterogeneous nuclear ribonucleoprotein H2)
RGD ID: 620840
Description: Enables enzyme binding activity. Involved in cellular response to peptide. Located in nucleoplasm. Is active in postsynaptic density. Human ortholog(s) of this gene implicated in Sjogren's syndrome. Orthologous to human HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1-bromopropane; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: heterogeneous nuclear ribonucleoprotein H; hnRNP H; Hnrph; Hnrph1; MGC124573; ratsg1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,187,412 - 35,203,909 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1035,193,890 - 35,203,906 (+)EnsemblGRCr8
mRatBN7.21034,692,868 - 34,702,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,693,555 - 34,702,846 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1039,365,683 - 39,374,987 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,904,939 - 7,914,243 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,359,365 - 34,368,669 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,872,619 - 35,879,911 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,870,232 - 35,879,910 (+)Ensemblrn6Rnor6.0
Rnor_5.01035,644,079 - 35,651,370 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41035,922,840 - 35,930,132 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1034,044,661 - 34,051,957 (+)NCBICelera
RGSC_v3.11035,923,888 - 35,931,180 (+)NCBI
Cytogenetic Map10q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-bromopropane  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3',5'-cyclic UMP  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aminoglutethimide  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP,ISO)
bufalin  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
ceruletide  (EXP)
chlorophyllin  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (EXP)
gentamycin  (EXP)
herbicide  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
metolachlor  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
progesterone  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sarin  (EXP)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tolcapone  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
2. Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors. Chettouh H, etal., Cancer Res. 2013 Jul 1;73(13):3974-86. doi: 10.1158/0008-5472.CAN-12-3824. Epub 2013 Apr 30.
3. Identification of immunodominant autoantigens in rat autoimmune orchitis. Fijak M, etal., J Pathol. 2005 Oct;207(2):127-38.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: relationship of heterogeneous nuclear ribonucleoproteins with prognosis. Hope NR and Murray GI, Hum Pathol. 2011 Mar;42(3):393-402. doi: 10.1016/j.humpath.2010.08.006. Epub 2010 Dec 30.
7. Proteomics analysis of rat brain postsynaptic density. Implications of the diverse protein functional groups for the integration of synaptic physiology. Li KW, etal., J Biol Chem. 2004 Jan 9;279(2):987-1002. doi: 10.1074/jbc.M303116200. Epub 2003 Oct 7.
8. Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction. Mantha AK, etal., J Neurosci Res. 2012 Jun;90(6):1230-9. doi: 10.1002/jnr.23018. Epub 2012 Feb 20.
9. The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. Matunis MJ, etal., Nucleic Acids Res 1994 Mar 25;22(6):1059-67.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus. Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
14. Heterogeneous nuclear ribonucleoprotein h1, a novel nuclear autoantigen. Van den Bergh K, etal., Clin Chem. 2009 May;55(5):946-54. doi: 10.1373/clinchem.2008.115626. Epub 2009 Mar 5.
15. Differentially expressed proteins in cerulein-stimulated pancreatic acinar cells: implication for acute pancreatitis. Yu JH, etal., Int J Biochem Cell Biol. 2008;40(3):503-16. Epub 2007 Sep 16.
Additional References at PubMed
PMID:1302261   PMID:11991638   PMID:12477932   PMID:16854843   PMID:16946708   PMID:18573884   PMID:19946888   PMID:22658674   PMID:22681889   PMID:24625528   PMID:24910439   PMID:26316108  
PMID:27117401   PMID:29476059   PMID:29581031   PMID:30361391   PMID:31505169   PMID:35352799  


Genomics

Comparative Map Data
Hnrnph1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,187,412 - 35,203,909 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1035,193,890 - 35,203,906 (+)EnsemblGRCr8
mRatBN7.21034,692,868 - 34,702,849 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1034,693,555 - 34,702,846 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1039,365,683 - 39,374,987 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0107,904,939 - 7,914,243 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,359,365 - 34,368,669 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01035,872,619 - 35,879,911 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1035,870,232 - 35,879,910 (+)Ensemblrn6Rnor6.0
Rnor_5.01035,644,079 - 35,651,370 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41035,922,840 - 35,930,132 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1034,044,661 - 34,051,957 (+)NCBICelera
RGSC_v3.11035,923,888 - 35,931,180 (+)NCBI
Cytogenetic Map10q22NCBI
HNRNPH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385179,614,178 - 179,634,784 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5179,614,170 - 179,634,784 (-)Ensemblhg38GRCh38
GRCh375179,041,179 - 179,061,785 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365178,973,786 - 178,983,276 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345178,973,785 - 178,983,276NCBI
Celera5174,670,146 - 174,679,127 (-)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,768,106 - 173,777,652 (-)NCBIHuRef
CHM1_15178,473,644 - 178,483,178 (-)NCBICHM1_1
T2T-CHM13v2.05180,168,628 - 180,189,994 (-)NCBIT2T-CHM13v2.0
Hnrnph1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,266,084 - 50,277,355 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,267,817 - 50,277,355 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381150,375,257 - 50,386,528 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,376,990 - 50,386,528 (+)Ensemblmm10GRCm38
MGSCv371150,191,221 - 50,200,030 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361150,221,186 - 50,229,948 (+)NCBIMGSCv36mm8
Celera1154,938,368 - 54,947,177 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.56NCBI
Hnrnph1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955408936,595 - 948,064 (+)Ensembl
ChiLan1.0NW_004955408937,706 - 944,969 (+)NCBIChiLan1.0ChiLan1.0
HNRNPH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24174,553,279 - 174,563,705 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,692,818 - 172,703,189 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,764,771 - 174,775,201 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15182,044,229 - 182,053,647 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5182,044,549 - 182,053,635 (-)EnsemblpanPan2panpan1.1
HNRNPH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1112,050,753 - 2,059,999 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl112,050,871 - 2,059,999 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha112,173,488 - 2,182,754 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0112,025,055 - 2,034,321 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl112,025,089 - 2,034,094 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1111,996,529 - 2,005,793 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0112,075,126 - 2,084,395 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0112,315,878 - 2,325,144 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hnrnph1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213119,925,451 - 119,934,866 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367391,135,289 - 1,144,643 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367391,135,282 - 1,144,643 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HNRNPH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl278,963,309 - 78,969,949 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1278,961,456 - 78,971,799 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2280,528,404 - 80,538,405 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HNRNPH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12381,330,777 - 81,340,470 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2381,330,351 - 81,339,882 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607512,697,976 - 12,708,643 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hnrnph1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473342,538,159 - 42,548,249 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473342,538,286 - 42,547,911 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hnrnph1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1933,035,385 - 33,044,599 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hnrnph1
193 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:118
Count of miRNA genes:55
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000059190, ENSRNOT00000067188
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
AA900513  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21034,702,518 - 34,702,702 (+)MAPPERmRatBN7.2
Rnor_6.01035,879,583 - 35,879,766NCBIRnor6.0
Rnor_5.01035,651,042 - 35,651,225UniSTSRnor5.0
RGSC_v3.41035,929,804 - 35,929,987UniSTSRGSC3.4
Celera1034,051,629 - 34,051,812UniSTS
RH 3.4 Map10369.2UniSTS
Cytogenetic Map10q22UniSTS
G43520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21034,697,502 - 34,697,636 (+)MAPPERmRatBN7.2
Rnor_6.01035,874,567 - 35,874,700NCBIRnor6.0
Rnor_5.01035,646,027 - 35,646,160UniSTSRnor5.0
RGSC_v3.41035,924,788 - 35,924,921UniSTSRGSC3.4
Celera1034,046,609 - 34,046,742UniSTS
Cytogenetic Map10q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_080896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF367468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000059190   ⟹   ENSRNOP00000055962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1035,194,607 - 35,203,906 (+)Ensembl
mRatBN7.2 Ensembl1034,693,602 - 34,702,846 (+)Ensembl
Rnor_6.0 Ensembl1035,872,619 - 35,879,910 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000067188   ⟹   ENSRNOP00000063584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1035,193,890 - 35,203,906 (+)Ensembl
mRatBN7.2 Ensembl1034,693,618 - 34,702,846 (+)Ensembl
Rnor_6.0 Ensembl1035,870,682 - 35,879,910 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000078505   ⟹   ENSRNOP00000068707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1035,193,933 - 35,199,789 (+)Ensembl
mRatBN7.2 Ensembl1034,693,555 - 34,701,513 (+)Ensembl
Rnor_6.0 Ensembl1035,870,232 - 35,878,775 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096910   ⟹   ENSRNOP00000093858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1035,193,890 - 35,203,906 (+)Ensembl
mRatBN7.2 Ensembl1034,693,632 - 34,702,845 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119006   ⟹   ENSRNOP00000079947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1035,194,689 - 35,203,906 (+)Ensembl
mRatBN7.2 Ensembl1034,693,632 - 34,702,845 (+)Ensembl
RefSeq Acc Id: NM_080896   ⟹   NP_543172
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,194,633 - 35,203,909 (+)NCBI
mRatBN7.21034,693,573 - 34,702,849 (+)NCBI
Rnor_6.01035,872,619 - 35,879,911 (+)NCBI
Rnor_5.01035,644,079 - 35,651,370 (+)NCBI
RGSC_v3.41035,922,840 - 35,930,132 (+)RGD
Celera1034,044,661 - 34,051,957 (+)RGD
Sequence:
RefSeq Acc Id: XM_039085094   ⟹   XP_038941022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,194,549 - 35,203,907 (+)NCBI
mRatBN7.21034,693,489 - 34,702,847 (+)NCBI
RefSeq Acc Id: XM_039085095   ⟹   XP_038941023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,194,689 - 35,203,907 (+)NCBI
mRatBN7.21034,693,695 - 34,702,277 (+)NCBI
RefSeq Acc Id: XM_039085096   ⟹   XP_038941024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,187,412 - 35,203,907 (+)NCBI
mRatBN7.21034,692,868 - 34,702,277 (+)NCBI
RefSeq Acc Id: XM_039085097   ⟹   XP_038941025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,194,696 - 35,203,907 (+)NCBI
mRatBN7.21034,693,636 - 34,702,277 (+)NCBI
RefSeq Acc Id: XM_039085099   ⟹   XP_038941027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,194,548 - 35,203,907 (+)NCBI
mRatBN7.21034,693,489 - 34,702,847 (+)NCBI
RefSeq Acc Id: XM_039085101   ⟹   XP_038941029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,194,549 - 35,203,345 (+)NCBI
mRatBN7.21034,693,489 - 34,702,847 (+)NCBI
RefSeq Acc Id: XM_063268352   ⟹   XP_063124422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,187,412 - 35,203,345 (+)NCBI
RefSeq Acc Id: XM_063268353   ⟹   XP_063124423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81035,196,897 - 35,203,907 (+)NCBI
RefSeq Acc Id: NP_543172   ⟸   NM_080896
- UniProtKB: Q8VHV7 (UniProtKB/Swiss-Prot),   A1L1J1 (UniProtKB/Swiss-Prot),   A6HE17 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063584   ⟸   ENSRNOT00000067188
Ensembl Acc Id: ENSRNOP00000068707   ⟸   ENSRNOT00000078505
Ensembl Acc Id: ENSRNOP00000055962   ⟸   ENSRNOT00000059190
RefSeq Acc Id: XP_038941024   ⟸   XM_039085096
- Peptide Label: isoform X1
- UniProtKB: Q8VHV7 (UniProtKB/Swiss-Prot),   A1L1J1 (UniProtKB/Swiss-Prot),   A0A8I6G5X8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941029   ⟸   XM_039085101
- Peptide Label: isoform X4
- UniProtKB: Q8VHV7 (UniProtKB/Swiss-Prot),   A1L1J1 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038941027   ⟸   XM_039085099
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AGL3 (UniProtKB/TrEMBL),   G3V9Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941022   ⟸   XM_039085094
- Peptide Label: isoform X1
- UniProtKB: Q8VHV7 (UniProtKB/Swiss-Prot),   A1L1J1 (UniProtKB/Swiss-Prot),   A0A8I6G5X8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941025   ⟸   XM_039085097
- Peptide Label: isoform X1
- UniProtKB: Q8VHV7 (UniProtKB/Swiss-Prot),   A1L1J1 (UniProtKB/Swiss-Prot),   A0A8I6G5X8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941023   ⟸   XM_039085095
- Peptide Label: isoform X1
- UniProtKB: Q8VHV7 (UniProtKB/Swiss-Prot),   A1L1J1 (UniProtKB/Swiss-Prot),   A0A8I6G5X8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079947   ⟸   ENSRNOT00000119006
Ensembl Acc Id: ENSRNOP00000093858   ⟸   ENSRNOT00000096910
RefSeq Acc Id: XP_063124422   ⟸   XM_063268352
- Peptide Label: isoform X3
- UniProtKB: Q8VHV7 (UniProtKB/Swiss-Prot),   A1L1J1 (UniProtKB/Swiss-Prot),   A6HE17 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124423   ⟸   XM_063268353
- Peptide Label: isoform X5
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VHV7-F1-model_v2 AlphaFold Q8VHV7 1-449 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697161
Promoter ID:EPDNEW_R7679
Type:multiple initiation site
Name:Hnrnph1_1
Description:heterogeneous nuclear ribonucleoprotein H1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01035,870,672 - 35,870,732EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620840 AgrOrtholog
BioCyc Gene G2FUF-25239 BioCyc
Ensembl Genes ENSRNOG00000003399 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000059190 ENTREZGENE
  ENSRNOT00000067188 ENTREZGENE
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:8363754 IMAGE-MGC_LOAD
InterPro ESRP UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  RRM_dom UniProtKB/Swiss-Prot
  Znf_CHHC UniProtKB/Swiss-Prot
KEGG Report rno:140931 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156600 IMAGE-MGC_LOAD
NCBI Gene 140931 ENTREZGENE
PANTHER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED UniProtKB/Swiss-Prot
Pfam RRM_1 UniProtKB/Swiss-Prot
  zf-RNPHF UniProtKB/Swiss-Prot
PhenoGen Hnrnph1 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003399 RatGTEx
SMART RRM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot
UniProt A0A8I6AGL3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5X8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABZ3NNF1_RAT UniProtKB/TrEMBL
  A1L1J1 ENTREZGENE
  A6HE17 ENTREZGENE, UniProtKB/TrEMBL
  G3V9Q3 ENTREZGENE, UniProtKB/TrEMBL
  HNRH1_RAT UniProtKB/Swiss-Prot
  Q499R8_RAT UniProtKB/TrEMBL
  Q8VHV7 ENTREZGENE
UniProt Secondary A1L1J1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-01 Hnrnph1  heterogeneous nuclear ribonucleoprotein H1  Hnrph1  heterogeneous nuclear ribonucleoprotein H1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Hnrph1  heterogeneous nuclear ribonucleoprotein H1  Hnrnph1    Symbol updated 1299863 APPROVED
2002-08-07 Hnrnph1  heterogeneous nuclear ribonucleoprotein H1      Symbol and Name status set to provisional 70820 PROVISIONAL