Slc25a27 (solute carrier family 25, member 27) - Rat Genome Database

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Gene: Slc25a27 (solute carrier family 25, member 27) Rattus norvegicus
Analyze
Symbol: Slc25a27
Name: solute carrier family 25, member 27
RGD ID: 620787
Description: Predicted to enable chloride transmembrane transporter activity; protein homodimerization activity; and proton transmembrane transporter activity. Involved in several processes, including intracellular triglyceride homeostasis; negative regulation of mitochondrial calcium ion concentration; and negative regulation of mitochondrial membrane potential. Located in apical part of cell and neuronal cell body. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SLC25A27 (solute carrier family 25 member 27); INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: mitochondrial uncoupling protein 4; Ucp4; uncoupling protein UCP-4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,804,183 - 24,831,219 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl924,804,185 - 24,831,217 (+)EnsemblGRCr8
mRatBN7.2917,306,898 - 17,333,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,307,023 - 17,332,731 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx925,896,938 - 25,922,631 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,971,478 - 30,997,179 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,260,717 - 29,286,408 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,880,468 - 19,907,506 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,880,473 - 19,907,458 (+)Ensemblrn6Rnor6.0
Rnor_5.0918,758,140 - 18,785,173 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4913,002,823 - 13,028,534 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera915,030,555 - 15,056,284 (+)NCBICelera
RGSC_v3.1913,000,144 - 13,025,851 (+)NCBI
Cytogenetic Map9q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2,4-trimethylbenzene  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aldehydo-D-glucose  (EXP)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
glucose  (EXP)
hydrogen peroxide  (EXP)
L-methionine  (EXP,ISO)
lead(0)  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
tunicamycin  (ISO)
undecane  (EXP)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. UCP4 overexpression improves fatty acid oxidation and insulin sensitivity in L6 myocytes. Gao CL, etal., J Bioenerg Biomembr. 2011 Apr;43(2):109-18. doi: 10.1007/s10863-011-9344-9. Epub 2011 May 24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress. Liu D, etal., Neuromolecular Med. 2006;8(3):389-414.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development. Smorodchenko A, etal., Biochim Biophys Acta. 2009 Oct;1788(10):2309-19. Epub 2009 Jul 30.
11. Role of mitochondrial uncoupling protein 4 in rat inner ear. Smorodchenko A, etal., Mol Cell Neurosci. 2011 Aug;47(4):244-53. Epub 2011 Mar 11.
12. Mitochondrial proton leak and the uncoupling protein 1 homologues. Stuart JA, etal., Biochim Biophys Acta 2001 Mar 1;1504(1):144-58.
13. Domoic acid induced spinal cord lesions in adult mice: evidence for the possible molecular pathways of excitatory amino acids in spinal cord lesions. Xu R, etal., Neurotoxicology. 2008 Jul;29(4):700-7. Epub 2008 May 1.
14. Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia. Yasuno K, etal., Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5;144B(2):250-3.
15. Overexpression of uncoupling protein 4 promotes proliferation and inhibits apoptosis and differentiation of preadipocytes. Zhang M, etal., Life Sci. 2006 Sep 5;79(15):1428-35. Epub 2006 Apr 27.
Additional References at PubMed
PMID:10025957   PMID:14651853   PMID:15464300   PMID:18614015   PMID:18992805   PMID:23266757   PMID:23800309  


Genomics

Comparative Map Data
Slc25a27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,804,183 - 24,831,219 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl924,804,185 - 24,831,217 (+)EnsemblGRCr8
mRatBN7.2917,306,898 - 17,333,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,307,023 - 17,332,731 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx925,896,938 - 25,922,631 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0930,971,478 - 30,997,179 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,260,717 - 29,286,408 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0919,880,468 - 19,907,506 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl919,880,473 - 19,907,458 (+)Ensemblrn6Rnor6.0
Rnor_5.0918,758,140 - 18,785,173 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4913,002,823 - 13,028,534 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera915,030,555 - 15,056,284 (+)NCBICelera
RGSC_v3.1913,000,144 - 13,025,851 (+)NCBI
Cytogenetic Map9q13NCBI
SLC25A27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,652,975 - 46,678,190 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,652,915 - 46,678,190 (+)Ensemblhg38GRCh38
GRCh37646,620,712 - 46,645,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,728,638 - 46,753,886 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34646,728,638 - 46,752,935NCBI
Celera648,173,194 - 48,198,451 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef646,343,936 - 46,369,200 (+)NCBIHuRef
CHM1_1646,624,101 - 46,649,353 (+)NCBICHM1_1
T2T-CHM13v2.0646,490,625 - 46,515,839 (+)NCBIT2T-CHM13v2.0
Slc25a27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,948,630 - 43,978,105 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,952,782 - 43,978,105 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381743,637,739 - 43,667,214 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,641,891 - 43,667,214 (-)Ensemblmm10GRCm38
MGSCv371743,778,849 - 43,803,964 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361743,104,955 - 43,130,070 (-)NCBIMGSCv36mm8
Celera1747,064,995 - 47,089,821 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.75NCBI
Slc25a27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543711,497,308 - 11,514,208 (+)Ensembl
ChiLan1.0NW_00495543711,497,308 - 11,514,208 (+)NCBIChiLan1.0ChiLan1.0
SLC25A27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2561,148,173 - 61,175,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1657,014,392 - 57,041,789 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0646,235,558 - 46,287,015 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,507,685 - 47,556,964 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,504,836 - 47,532,655 (+)EnsemblpanPan2panpan1.1
SLC25A27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,818,385 - 14,846,688 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,818,541 - 14,846,700 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1214,849,780 - 14,872,673 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01215,318,189 - 15,346,646 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1215,318,244 - 15,343,998 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,833,979 - 14,856,823 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01214,922,871 - 14,945,764 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01215,019,528 - 15,042,410 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc25a27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494650,262,753 - 50,288,115 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647613,671,860 - 13,697,451 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647613,674,153 - 13,697,449 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl741,426,170 - 41,457,883 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1741,426,161 - 41,457,887 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,092,192 - 48,121,659 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11725,596,757 - 25,621,202 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1725,598,242 - 25,621,238 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604446,671,344 - 46,695,785 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475413,961,734 - 13,980,090 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475413,961,601 - 13,980,089 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc25a27
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1486,175,434 - 86,202,203 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc25a27
152 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:567
Count of miRNA genes:267
Interacting mature miRNAs:338
Transcripts:ENSRNOT00000052068
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)9131250552Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)949664545496645Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9141763315Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9671488829567695Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)949664545496645Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)92103143049025574Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)949664545496645Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 69 154 91 90 59 73 59 6 336 175 11 134 78 92 31 18 18

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006244612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063267787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ300162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ300163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ300164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY512661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000052068   ⟹   ENSRNOP00000039207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl924,804,185 - 24,831,217 (+)Ensembl
mRatBN7.2 Ensembl917,307,023 - 17,332,731 (+)Ensembl
Rnor_6.0 Ensembl919,880,473 - 19,907,458 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098372   ⟹   ENSRNOP00000094770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl924,805,206 - 24,831,217 (+)Ensembl
mRatBN7.2 Ensembl917,308,863 - 17,332,731 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098398   ⟹   ENSRNOP00000082945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,308,863 - 17,332,731 (+)Ensembl
RefSeq Acc Id: NM_053500   ⟹   NP_445952
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,308 - 24,830,017 (+)NCBI
mRatBN7.2917,307,023 - 17,332,736 (+)NCBI
Rnor_6.0919,880,593 - 19,906,304 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
RGSC_v3.4913,002,823 - 13,028,534 (+)RGD
Celera915,030,555 - 15,056,284 (+)RGD
Sequence:
RefSeq Acc Id: XM_006244610   ⟹   XP_006244672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,328,614 (+)NCBI
Rnor_6.0919,880,468 - 19,901,907 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244611   ⟹   XP_006244673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,333,942 (+)NCBI
Rnor_6.0919,880,468 - 19,907,506 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006244612   ⟹   XP_006244674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,333,942 (+)NCBI
Rnor_6.0919,880,468 - 19,907,506 (+)NCBI
Rnor_5.0918,758,140 - 18,785,173 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008766882   ⟹   XP_008765104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,938 - 24,831,219 (+)NCBI
mRatBN7.2917,307,658 - 17,328,614 (+)NCBI
Rnor_6.0919,881,230 - 19,907,506 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039084299   ⟹   XP_038940227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,183 - 24,831,219 (+)NCBI
mRatBN7.2917,306,898 - 17,328,614 (+)NCBI
RefSeq Acc Id: XM_039084300   ⟹   XP_038940228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,471 - 24,831,219 (+)NCBI
mRatBN7.2917,307,184 - 17,328,614 (+)NCBI
RefSeq Acc Id: XM_039084302   ⟹   XP_038940230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,805,443 - 24,831,219 (+)NCBI
mRatBN7.2917,309,099 - 17,328,614 (+)NCBI
RefSeq Acc Id: XM_039084303   ⟹   XP_038940231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,395 - 24,831,219 (+)NCBI
mRatBN7.2917,307,110 - 17,331,294 (+)NCBI
RefSeq Acc Id: XM_063267787   ⟹   XP_063123857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,804,475 - 24,831,219 (+)NCBI
RefSeq Acc Id: NP_445952   ⟸   NM_053500
- UniProtKB: Q9EPH7 (UniProtKB/TrEMBL),   A6JJ30 (UniProtKB/TrEMBL),   A6JJ28 (UniProtKB/TrEMBL),   F7F692 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244673   ⟸   XM_006244611
- Peptide Label: isoform X2
- UniProtKB: Q9EPH6 (UniProtKB/TrEMBL),   A0A8I6ALR4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244674   ⟸   XM_006244612
- Peptide Label: isoform X4
- UniProtKB: A6JJ28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244672   ⟸   XM_006244610
- Peptide Label: isoform X1
- UniProtKB: Q9EPH5 (UniProtKB/TrEMBL),   A6JJ28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008765104   ⟸   XM_008766882
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000039207   ⟸   ENSRNOT00000052068
RefSeq Acc Id: XP_038940227   ⟸   XM_039084299
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038940231   ⟸   XM_039084303
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038940228   ⟸   XM_039084300
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038940230   ⟸   XM_039084302
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000094770   ⟸   ENSRNOT00000098372
Ensembl Acc Id: ENSRNOP00000082945   ⟸   ENSRNOT00000098398
RefSeq Acc Id: XP_063123857   ⟸   XM_063267787
- Peptide Label: isoform X6
- UniProtKB: Q6R5J6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6R5J6-F1-model_v2 AlphaFold Q6R5J6 1-275 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620787 AgrOrtholog
BioCyc Gene G2FUF-28118 BioCyc
Ensembl Genes ENSRNOG00000010592 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000052068 ENTREZGENE
  ENSRNOT00000052068.5 UniProtKB/TrEMBL
  ENSRNOT00000098372 ENTREZGENE
  ENSRNOT00000098372.2 UniProtKB/TrEMBL
Gene3D-CATH 1.50.40.10 UniProtKB/TrEMBL
InterPro Mito_Metabolite_Transporter UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/TrEMBL
  Mt_carrier_dom UniProtKB/TrEMBL
KEGG Report rno:85262 UniProtKB/TrEMBL
NCBI Gene 85262 ENTREZGENE
PANTHER MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/TrEMBL
PhenoGen Slc25a27 PhenoGen
PROSITE SOLCAR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010592 RatGTEx
Superfamily-SCOP Mitoch_carrier UniProtKB/TrEMBL
UniProt A0A8I6ALR4 ENTREZGENE, UniProtKB/TrEMBL
  A6JJ28 ENTREZGENE, UniProtKB/TrEMBL
  A6JJ30 ENTREZGENE, UniProtKB/TrEMBL
  F7F692 ENTREZGENE, UniProtKB/TrEMBL
  Q6R5J6 ENTREZGENE, UniProtKB/TrEMBL
  Q9EPH5 ENTREZGENE, UniProtKB/TrEMBL
  Q9EPH6 ENTREZGENE, UniProtKB/TrEMBL
  Q9EPH7 ENTREZGENE
UniProt Secondary Q9EPH7 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Slc25a27  solute carrier family 25, member 27  Ucp4  uncoupling protein UCP-4  Symbol and Name updated 1299863 APPROVED
2002-08-07 Ucp4  uncoupling protein UCP-4      Symbol and Name status set to provisional 70820 PROVISIONAL